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Bibliometric analysis of phosphoglycerate kinase 1 expression in breast cancer and its distinct upregulation in triple-negative breast cancer

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World Journal of Clinical Oncology 2024年第7期15卷 867-894页

作者： jing-yu chen Jian-Di Li Rong-Quan He Zhi-Guang Huang Gang chen Wen Zou Department of Pathology First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Medical Oncology First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Phosphoglycerate kinase 1(PGK1)has been identified as a possible biomarker for breast cancer(BC)and may play a role in the development and advancement of triple-negative BC(TNBC).AIM To explore the PGK1 and BC research status and PGK1 expression and mecha-nism differences among TNBC,non-TNBC,and normal breast *** PGK1 and BC related literature was downloaded from Web of Science Core Co-llection Core *** counts,key-word frequency,cooperation networks,and theme trends were *** breast,TNBC,and non-TNBC mRNA data were gathered,and differentially expressed genes *** under the summary receiver operating characteristic curves,sensitivity and specificity of PGK1 expression were *** Meier revealed PGK1’s prognostic ***1 co-expressed genes were explored,and Gene Onto-logy,Kyoto Encyclopedia of Genes and Genomes,and Disease Ontology ***-protein interaction networks were *** genes *** PGK1 and BC related publications have surged since 2020,with China leading the *** most frequent keyword was“Expression”.Collaborative networks were found among co-citations,countries,institutions,and ***1 expression and BC progression were research hotspots,and PGK1 expression and BC survival were research *** 16 TNBC vs non-cancerous breast and 15 TNBC vs non-TNBC datasets,PGK1 mRNA levels were higher in 1159 TNBC than 1205 non-cancerous breast cases[standardized mean differences(SMD):0.85,95%confidence interval(95%CI):0.54-1.16,I²=86%,P<0.001].PGK1 expression was higher in 1520 TNBC than 7072 non-TNBC cases(SMD:0.25,95%CI:0.03-0.47,I²=91%,P=0.02).Recurrence free survival was lower in PGK1-high-expression than PGK1-low-expression group(hazard ratio:1.282,P=0.023).PGK1 co-expressed genes were concentrated in ATP metabolic process,HIF-1 signaling,and glycolysis/gluconeogenesis *** PGK1 expression is a research hotspot and frontier dire

关键词： Phosphoglycerate kinase 1 Breast cancer Triple-negative breast cancer Bibliometric analysis Computational pathology

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探究地球物理勘查技术在铝矿地质勘查中的应用

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世界有色金属 2024年第10期 163-165页

作者：景晨宇河北省煤田地质局第二地质队(河北省干热岩研究中心) 河北邢台054000

本文将率先介绍地球物理勘查技术的主要类型,再通过专业的研究与调查,精准找出该技术在铝矿地质勘查中的实践运用,应用内容包括密集空间勘查、地下水资源勘查、地球物理测井、地质遥感勘查及地震勘查等,然后以某区域金属矿产地质勘查为... 详细信息

本文将率先介绍地球物理勘查技术的主要类型,再通过专业的研究与调查,精准找出该技术在铝矿地质勘查中的实践运用,应用内容包括密集空间勘查、地下水资源勘查、地球物理测井、地质遥感勘查及地震勘查等,然后以某区域金属矿产地质勘查为例,详细阐述地球物理勘查技术在地质勘查中的应用过程,全面展现该项技术的使用优势,保障铝矿地质勘查质量。

关键词：地质勘查铝矿物理勘查技术

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Dual-wavelength dual-indicator catalytic kinetic spectrophotometry for determination of trace Ru(Ⅲ)

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Rare Metals 2013年第6期32卷 605-608页

作者： Hai-Yan chen yu-jing chen Ming Zhang School of Chemistry and Chemical Engineering Yangzhou University Department of Chemical Engineering Yangzhou Polytechnic InstituteYangzhou 225127 China School of Chemistry and Materials Science Ludong University

A new dual-wavelength dual-indicator catalytic kinetic spectrophotometric method for the determination of trace Ru(III)was *** method was based on Ru(III)-catalyzing oxidation of Arsenazo I and indigo carmine by potassium bromate in sulfuric *** absorbances of the catalytic and noncatalytic systems were measured at 510 and610 nm,*** the optimum conditions,the linear range of determination is 0–0.12 lgáml-1and the detection limit is 1.21 9 10-4lgá*** method was applied for the determination of trace Ru(III)in ore samples with satisfactory results.

关键词： Dual-wavelength Catalytic spectrophotometry Ru(III) Arsenazo I Indigo carmine

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Bilateral lung transplantation,a new option for pulmonary metastasis from hepatocellular carcinoma?

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Hepatobiliary & Pancreatic Diseases International 2023年第1期22卷 96-98页

作者： Zi-Tao Wang jing-yu chen Department of Thoracic Surgery Wuxi Lung Transplant CenterWuxi People’s Hospital Affiliated to Nanjing Medical UniversityWuxi 214023China Department of Lung Transplant the Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China

To the Editor:The lung is the most frequent site of extrahepatic hepatocellular carcinoma(HCC)recurrence after liver transplantation(LT).Pulmonary metastasis from hepatocellular carcinoma(PM-HCC)carries a poor prognosis as the patient could finally die of pulmonary failure secondary to the tumor despite maintaining ideal liver function.

关键词： metastasis hepatocellular lung

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Weighted cooperative routing for wireless mobile Ad-hoc network

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The Journal of China Universities of Posts and Telecommunications 2007年第1期14卷 16-21页

作者： ZHAO Xian-jing ZHENG Bao-yu chen Chao Institute of Signal and Information Processing Nanjing University of Posts and Telecommunications Nanjing 210003 China

A novel weighted cooperative routing algorithm （WCRA） is proposed in this article, which was on the basis of a weighted metric with maximal remaining energy （MRE） of the relays and the maximal received SNR （MRS） of the nodes. Moreover, a cooperative routing protocol was implemented on the basis of WCRA. Then simulation is done on network simulation （NS-2） platform to compare the performances of MRS, MRE and WCRA with that of noncooperative destination-sequenced destination-sequenced distance-vector （DSDV） protocol. The simulative results show that WCRA obtains a performance tradeoff between MRE and MRS in terms of delivery ratio and network lifetime, which can effectively improve the network lifetime at an acceptable loss of delivery ratio.

关键词： weighted cooperative routing Ad-hoc networks,quality of service DSDV routing protocol

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Cross-talk between MEK1/2-ERK1/2 signaling and G protein-couple signaling in synoviocytes of collagen-induced arthritis rats

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Chinese Medical Journal 2008年第22期121卷 2278-2283页

作者： ZHANG Ling-ling WEI Wei WANG Qing-tong chen jing-yu chen Yin Institute of Clinical Pharmacology Anhui Medical University Key Laboratory of Anti-inflammatory and Immuno-pharmacology in Anhui Province Key Laboratory of Research & Development of Chinese Medicine in Anhui Province Hefei Anhui 230032 China

Background Signaling pathways that regulate the production of cytokines and destructive enzymes have been implicated in rheumatoid arthritis （RA） pathogenesis. There are co-relations between signaling pathways. The aim of this study was to investigate interactions and cross-talks between MEK1/2-extracellular signal-related kinase （ERK1/2） signaling and G protein-couple signaling in synoviocytes of collagen-induced arthritis （CIA） rats by the stimulation of interleukin-1 （IL-1）, U0126, isoprenaline hydrochloride and aminophyline respectively. Methods Twenty Sprague-Dawley （SD） rats were induced by chicken type II collagen. Synoviocytes of CIA rats were isolated and cultured. The expressions of Gi, phosphorylated MEK1/2 （p-MEK1/2） and phosphorylated ERK1/2 （p-ERK1/2） were detected by Western blotting, cAMP level and protein kinase A （PKA） activity were measured by radioimmunoassay and kinase-glo luminescent kinase assay respectively. Results There was remarkable inflammation in CIA rats accompanied by swelling paws, hyperplastic synovium, pannus and cartilage erosion, cAMP level and PKA activity of synoviocytes decreased. Gi, p-ERK1/2 and p-MEK1/2 increased, rlL-la improved the expression of Gi, p-ERK1/2 and p-MEK1/2, cAMP and PKA increased with stimulation of rlL-1α. U0126 inhibited Gi, cAMP and PKA of synoviocytes stimulated by rlL-la. Isoprenaline hydrochloride enhanced Gi, cAMP and PKA, but had no effects on p-MEK1/2 and p-ERK1/2. Aminophyline increased cAMP and PKA, but inhibited p-MEK1/2 and p-ERK1/2. Conclusions Mitogen-activated protein kinases （MAPKs） and G protein-couple signaling are associated with synovitis. There are cross talks between MAPKs and G protein-couple signaling. The two signaling pathways represent potential therapeutic targets for RA.

关键词： arthritis signaling cross-talk G protein MAP kinases

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Pediatric case report:successful bilateral lung transplantation performed to treat an 8-year-old girl with pulmonary interstitial fibrosis due to surfactant protein(SP)-C gene mutation

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Chinese Medical Journal 2021年第4期134卷 498-500页

作者： Feng Liu yu-Lin Jin Hui-Xing Li yuan chen Bo Wu Lin-Zhi Shi jing-yu chen Lung Transplant Center Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxiJiangsu 214023China

To the Editor:Pediatric lung transplantation is a highly specialized therapy for end stage pulmonary disease in children,and is performed in only a handful of transplant centers around the *** the past decade,about 100 cases of pediatric lung transplantation have been performed annually all over the *** centers perform 1 to 4 pediatric lung transplantations annually,with only five centers performing more than five per *** 2007,our team has performed lung transplantations in 12 pediatric patients,among whom 11 were over 10 years old.

关键词： lung Pediatric annually

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Advancement in porphyrin/phthalocyanine compounds-based perovskite solar cells

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结构化学 2024年第3期43卷 55-66页

作者： chen Lu Zefeng yu jing Cao State Key Laboratory of Applied Organic Chemistry Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu ProvinceCollege of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou730000PR China

Porphyrin and phthalocyanine compounds belong to a class of large and aromatic macrocyclic *** to their unique structures and electronic properties,they have found widespread applications in optoelectronic *** recent years,the doping of porphyrins and phthalocyanines into perovskite solar cells(PSCs)has emerged as an effective strategy to enhance device performance and *** doping strategy enables the modulation of perovskite film crystallization and surface defects,thereby improving charge transfer and enhancing the photo-conversion *** sensitizers,porphyrins and phthalocyanines absorb light in the visible and near-infrared spectral ranges,providing an advantage to the light absorption characteristics of ***,their roles in interface modification and defect repair contribute to the long-term stability of the *** central metal of porphyrin can also adsorb ions and prevent the migration of harmful *** review summarizes the recent progress in the research on porphyrin and phthalocyanine-doped PSCs,empha-sizing their potential value in enhancing optoelectronic performance,increasing stability and expanding the application scope of these devices.

关键词： Porphyrin Phthalocyanine Charge transport Interfacial chemistry Perovskite solar cells

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Expression of PIN Genes in Rice （Oryza sativa L.）： Tissue Specificity and Regulation by Hormones

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Molecular Plant 2009年第4期2卷 823-831页

作者： Ji-Rong Wang Han Hu Gao-Hang Wang jing Li Jie-yu chen Ping Wu State Key Laboratory of Plant Physiology and Biochemistry College of Life Sciences Zi Jin Gang Campus Zhejiang University Hangzhou 310058 People's Republic of China

Twelve genes of the PIN family in rice were analyzed for gene and protein structures and an evolutionary relationship with reported AtPINs in Arabidopsis. Four members of PIN1 （designated as OsPINla-d）, one gene paired with AtPIN2 （OsPIN2）, three members of PIN5 （OsPIN5a-c）, one gene paired with AtPIN8 （OsPIN8）, and three monocot-specific PINs （OsPIN9, OsPINIOa, and b） were identified from the phylogenetic analysis. Tissue-specific expression patterns of nine PIN genes among them were investigated using RT-PCR and GUS reporter. The wide variations in the expression domain in different tissues of the PIN genes were observed. In general, PIN genes are up-regulated by exogenous auxin, while different responses of different PIN genes to other hormones were found.

关键词： Oryza sativa L. PIN family expression pattern.

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Pulmonary arterial stent for pulmonary trunk stenosis after size-mismatched lung transplantation

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Chinese Medical Journal 2019年第10期132卷 1247-1249页

作者： Fei Xiao Chao-Yang Liang Wen-Hui chen Min Li Xin-Cao Tao He chen jing-yu chen Department of Thoracic Surgery China-Japan Friendship Hospital Beijing 100029 China Department of Lung Transplantation China-Japan Friendship Hospital Beijing 100029 China Department of Pulmonary and Critical Care Medicine China-Japan Friendship Hospital Beijing 100029 China Department of Radiology China-Japan Friendship Hospital Beijing 100029 China

To the Editor: Appropriate donor-to-recipient size matching is of crucial importance in lung transplantation. Although tailoring of the lung has been described as a successful means of overcoming size disparities, its merits and demerits remain unclear. Here, we present a case of recurrent hypoxemia after unmatched single lung transplantation.

关键词： pulmonary trunk stenosis Pulmonary arterial lung transplantation

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