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Lactobacillus levels and prognosis of patients with acute myocardial infarction

Journal of Geriatric Cardiology 2022年第2期19卷 101-114页

作者： jing-jing CAI Yin LIU Jie wang jing-xian wang Yuan wang Shi-Bo XU Zhuang CUI jing GAO Graduate School Tianjin Medical UniversityTianjinChina Department of Cardiology Xing’anmeng People’s HospitalInner MongoliaChina Clinical School of Thoracic Tianjin Medical UniversityTianjinChina Department of Cardiology Tianjin Chest HospitalTianjinChina School of Public Health Tianjin Medical UniversityTianjinChina Cardiovascular Institute Tianjin Chest HospitalTianjinChina

OBJECTIVE To explore the relationship between Lactobacillus and prognosis of acute myocardial infarction(AMI)patients treated by percutaneous coronary intervention(PCI)and its correlation with clinical *** Consecutive patients with AMI in the coronary care unit of Tianjin Chest Hospital in China who received emergency PCI between July 2017 and December 2018 were ***’fecal 16 S r DNA gene sequencing data were analyzed and subjects were categorized into low,medium and high level groups according to stool Lactobacillus *** primary endpoints were major adverse cardiac *** regression analysis was used to analyze the relationship between Lactobacillus and *** correlation analysis and trend tests were used to assess the relationship between Lactobacillus and the clinical *** The data of 254 patients were included in the *** age was 65.90±11.56 years,and 152 patients(59.84%)were ***-up time was 652(548.25-753.00)*** Cox regression analysis showed a significantly lower risk of major adverse cardiac events in patients with Lactobacillus>7.1 copies/g[adjusted hazard ratio(HR)=0.216,95%CI:0.094-0.493,P<0.001]compared to patients with Lactobacillus≤3.6 copies/*** significant differences were shown in ST-segment elevation myocardial infarction(STEMI)(HR=0.217,95%CI:0.085-0.551,P=0.001).Lactobacillus was a protective factor for male smokers aged over 60 years whose brain natriuretic peptide was over 1,000 pg/m *** correlation analysis showed that Lactobacillus correlated negatively with white blood cells,neutrophils,high-sensitivity C-reactive protein,Troponin T,creatine kinase,creatine kinase-MB and brain natriuretic peptide(downward trend),and correlated positively with left ventricular ejection fraction(upward trend).CONCLUSIONS This study is the first to reveal the correlation between Lactobacillus and inflammation and myocardial damage after STEMI.

关键词： patients infarction prognosis

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ELECTROSTATIC INTERACTION HYBRIDS FROM WATER-BORNE CONDUCTIVE POLYANILINE AND INORGANIC PRECURSOR CONTAINING CARBOXYL GROUP

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Chinese Journal of Polymer Science 2007年第2期25卷 181-186页

作者： jing Luo xian-hong wang Ji Li Xiao-jiang Zhao Fo-song wang State Key Laboratory of Polymer Physicsand Chemistry Changchun Institute of Applied Chermstry Graduate School of Chinese Academy of Sciences Changchun 130022 China

Electrostatic interaction conductive hybrids were prepared in water/ethanol solution by the sol-gel process from inorganic sol containing carboxyl group and water-borne conductive polyaniline （cPANI）. The electrostatic interaction hybrids film displayed 1-2 orders of magnitude higher electrical conductivity in comparison with common hybrids film, showing remarkable conductivity stability against water soaking. Most strikingly, it displayed ideal electrochemical activity even in a solution with pH = 14, which enlarged the conducting polyaniline application window to strong alkaline media.

关键词： Water-borne conductive polyaniline Sol-gel Electrostatic interaction.

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Combined fascia iliaca compartment block and monitored anesthesia care for geriatric patients with hip fracture: Two case reports

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World Journal of Clinical Cases 2021年第27期9卷 8268-8273页

作者： Li Zhan Yu-Jie Zhang jing-xian wang Department of Anesthesiology Lu’an Affiliated Hospital of Anhui Medical UniversityAnhui Medical UniversityLu’an 237005Anhui ProvinceChina

BACKGROUND Major hip surgery usually requires neuraxial or general anesthesia with tracheal intubation and may be supplemented with a nerve block to provide intraoperative and postoperative pain *** SUMMARY This report established that hip surgical procedures can be performed with a fascia iliaca compartment block(FICB)and monitored anesthesia care(MAC)while avoiding neuraxial or general *** was a preliminary experience with two geriatric patients with hip fracture,American Society of Anesthesiologists status III,and with many *** patient could be operated on within 48 h after *** general anesthesia and neuraxial anesthesia were high-risk procedures and had ***,we chose nerve block combined with a small amount of *** analgesia was provided by single-injection ultrasound-guided *** intravenous sedation was *** exposure was satisfactory,and neither patient complained of any symptoms during the *** This report showed that hip surgery for geriatric patients can be performed with FICB and MAC,although complications and contraindications are *** anesthetic program was accompanied by stable respiratory and circulatory system responses and satisfactory analgesia while avoiding the adverse effects and problems associated with either neuraxial or general anesthesia.

关键词： Fascia iliaca compartment block Monitored anesthesia care Geriatric Hip fracture Ultrasound-guided Case report

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Clinical observation of vitrectomy combined with endolaser photocoagulation at the edge of posterior scleral staphyloma for macular hole retinal detachment in high myopia

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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1650-1656页

作者： Xiao-Tian Zhang jing-xian wang Song Chen Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300020China Tianjin Eye Hospital Tianjin 300020China Tianjin Key Laboratory of Ophthalmology and Visual Science Tianjin300020China Tianjin Medical University Tianjin 300070China

AIM: To observe the clinical effect of pars plana vitrectomy(PPV) and silicone oil filling surgery combined with intraoperative posterior scleral staphyloma(PS) marginal retinal photocoagulation in the treatment of high myopic macular hole retinal detachment(MHRD) with ***: This was a retrospective clinical study. From May 2017 to March 2020, 62 MHRD patients with PS(62 eyes) were enrolled in the study. Patients were divided into 23 G PPV combined with PS marginal retina intraoperative photocoagulation group(combined group) and conventional surgery group(conventional group), with 31 eyes in each. Triamcinolone acetonide and indocyanine green were used to remove the epiretinal membrane and the posterior macular inner limiting membrane(ILM). In the combined group, 2 to 3 rows of retinal photocoagulation were performed on the edge of the PS. The patients were followed up for an average of 8.34±3.21 mo. The first retinal reattachment rate, macular hole closure rate, Duration of silicone oil tamponade, best corrected visual acuity(BCVA) and average number of operations were observed and compared between the two ***: The first retinal reattachment rates of the eyes in the combined group and the conventional group were 96.7%(29/31) and 67.7%(21/31), respectively(χ~2=6.613, P=0.010). The macular hole closure rates in the combined group and the conventional group were 74.2%(23/31) and 67.7%(21/31), respectively(χ~2=0.128, P=0.721). The Duration of silicone oil tamponade of the patients in the combined group was lower than that of the routine group(t=-41.962, P≤0.001). Postoperative log MAR BCVA values of patients in the combined group and the conventional group were 1.27±0.12 and 1.26±0.11, compared with the log MAR BCVA before surgery, each group was improved(t=19.947, t=-19.517, P≤0.001, P≤0.001). There was no significant difference in the log MAR BCVA between the eyes of the two groups(t=-0.394, P=0.695). The average numbers of operations on the eyes in

关键词： macular hole retinal detachment high myopia posterior scleral staphyloma retinal photocoagulation vitrectomy

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Development of a Multiplex PCR for Diagnosis of Staphylococcus aureus, Escherichia coli and Bacillus cereus from Cows with Endometritis

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Agricultural Sciences in China 2011年第10期10卷 1624-1629页

作者： SUN Dong-bo WU Rui HE xian-jing wang Shuang LIN Yun-cheng HAN Xu wang Yue-qiang GUOTing-ting WU Guo-jun YANG Ke-li College of Animal Science and Veterinary Medicine Heilongjiang Bayi Agricultural University Daqing 163319 P.R.China

Staphylococcus aureus, Escherichia coli and Bacillus cereus are the major agents of cow endometritis in dairy cows. A multiplex PCR （SEB-mPCR） was established based on the conserved genes of S. aureus, E. coli and B. cereus, and the detection limits were 103, 102 and 103 CFU mL-1, respectively. SEB-mPCR could not amplify genomic DNA of pathogenic bacteria of other common bovine diseases. A total of 309 vaginal discharge samples from cows with endometritis were tested by SEB-mPCR. Of the samples, 23.95% had the three kinds of bacteria detected, 17.15% had S. aureu and E. coli, 9.39% had E. coli and B. cereus, and 9.71% had S. aureus and B. cereus. The rates of infections with S. aureus, E. coli and B. cereus were 11.35, 16.18 and 9.06%, respectively. Therefore, SEB-mPCR has a potential as a diagnosis tool for endometritis in dairy cows.

关键词： bovine endometritis multiplex PCR S. aureus E. coli B. cereus

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Balanced nitrogen–iron sufficiency boosts grain yield and nitrogen use efficiency by promoting tillering

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Molecular Plant 2023年第12期16卷 1661-1677页

作者： Ying Song Guang-Yu Wan jing-xian wang Zi-Sheng Zhang Jin-Qiu Xia Liang-Qi Sun Jie Lu Chuan-Xi Ma Lin-Hui Yu Cheng-Bin xiang Jie Wu Division of Life Sciences and Medicine Division of Molecular&Cell BiophysicsHefei National Science Center for Interdisciplinary Sciences at the MicroscaleMOE Key Laboratory for Membraneless Organelles and Cellular DynamicsUniversity of Science and Technology of ChinaThe Innovation Academy of Seed DesignChinese Academy of SciencesHefeiAnhui Province 230027China School of Agronomy Anhui Agricultural UniversityHefeiAnhui Province 230036China State Key Laboratory of Crop Stress Biology for Arid Areas and Institute of Future Agriculture Northwest A&F UniversityYanglingShaanxi 712100China

Crop yield plays a critical role in global food *** optimal plant growth and maximal crop yields,nutrients must be ***,the potential significance of balanced nitrogen-iron(N-Fe)for improving crop yield and nitrogen use efficiency(NUE)has not previously been ***,we show that balanced N-Fe sufficiency significantly increases tiller number and boosts yield and NUE in rice and ***-like protein 4(OsNLP4)plays a pivotal role in maintaining the N-Fe balance by coordinately regulating the expression of multiple genes involved in N and Fe metabolism and ***4 also suppresses OsD3 expression and strigolactone(SL)signaling,thereby promoting *** N-Fe sufficiency promotes the nuclear localization of OsNLP4 by reducing H_(2)O_(2) levels,reinforcing the functions of ***,we found that OsNLP4 upregulates the expression of a set of H2O2-scavenging genes to promote its own accumulation in the ***,we demonstrated that foliar spraying of balanced N-Fe fertilizer at the tillering stage can effectively increase tiller number,yield,and NUE of both rice and wheat in the ***,these findings reveal the previously unrecognized effects of N-Fe balance on grain yield and NUE as well as the molecular mechanism by which the OsNLP4-OsD3 module integrates N-Fe nutrient signals to downregulate SL signaling and thereby promote rice *** study sheds light on how N-Fe nutrient signals modulate rice tillering and provide potential innovative approaches that improve crop yield with reduced N fertilizer input for benefitting sustainable agriculture worldwide.

关键词： nitrogen-iron balance tller NUE grain yield OsNLP4 rice

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Discussion on the Fundamental Role of Traditional Culture in the Development of Traditional Chinese Medicine--Using Ophthalmology As An Example

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History & Philosophy of Medicine 2019年第1期1卷 8-12页

作者： Li-Hao Chen Shu-Yan Zhang Jiang-Wei Li xian-jing wang Hunan University of Traditional Chinese medicine Changsha410208China

Traditional Chinese medicine(TCM)was developed from and is rooted in traditional Chinese ***,the Chinese state attaches great importance to the development of TCM and has implemented a series of policies and *** paper first demonstrates the rationality of the view that"traditional culture plays a fundamental role in the development of TCM",and analyzes the influence of traditional culture on the development of TCM from the perspective of philosophy and religion,in order to have a deeper understanding of the formation and development process of ***,taking ophthalmology of TCM as an example,this paper discusses the importance of the continual inheritance of traditional culture and development of TCM.

关键词： Traditional culture History Philosophy Religion,Traditional Chinese medicine Ophthalmology of traditional Chinese medicine

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Correlation between 1,5-anhydroglucitol and glycemic excursions in type 2 diabetic patients

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Chinese Medical Journal 2011年第22期124卷 3641-3645页

作者： SUN Jie DOU jing-tao wang xian-ling YANG Guo-qing LU Zhao-hui ZHENG Hua MA Fang-ling LU Ju-ming MU Yi-ming Department of Endocrinology Chinese People＇s Liberation Army General Hospital Beijing 100853 China

Background The accurate and comprehensive assessment of glycemic control in patients with diabetes is important for optimizing glycemic management and for formulating personalized diabetic treatment schemes. This study aimed to analyze the correlation between 1,5-anhydroglucitol （1,5-AG） and glycemic excursions in type 2 diabetic patients. Methods Seventy-one outpatients with type 2 diabetes mellitus were randomly recruited from Chinese People＇s Liberation Army General Hospital. Using a continuous glucose monitoring system （CGMS）, these patients＇ blood glucose levels were monitored for three consecutive days to obtain mean blood glucose （MBG） data. Intraday glycemic excursions were evaluated using the mean amplitude of glycemic excursions （MAGE）, the largest amplitude of glycemic excursions （LAGE）, standard deviation of blood glucose （SDBG） and the M-value. Interday glycemic excursion was assessed by absolute mean of daily difference （MODD）. Postprandial glycemic fluctuations were evaluated using postprandial glucose excursions （PPGE） and postprandial incremental area under the curve （iAUC）. Fasting venous blood samples were collected to measure serum 1,5-AG, whole-blood hemoglobin Alc （HbAlc） and serum glycated albumin （GA）. Clinical markers of glycemia and parameters of glycemic excursions from CGMS were analyzed using the Pearson correlation coefficient and multivariate stepwise regression. Results Pearson correlation analysis revealed that 1,5-AG was significantly correlated with MAGE, SDBG, M-value, LAGE, PPGE and iAUC （r values were-0.509,-0.430,-0.530,-0.462,-0.416 and-0.435, respectively, P 〈0.01）, especially in moderately and well-controlled patients, based on defined HbAlc levels. Multivariate stepwise regression analysis revealed a negative correlation between 1,5-AG and the above parameters, but not HbAlc and GA. Finally, HbAlc and GA were positively correlated with MBG and fasting blood glucose （FBG）. Conclusions 1,5-AG was much better than HbAlc and GA

关键词： 1,5-anhydroglucitol type 2 diabetes mellitus glycemic excursions

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