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Multilinear Calderón-Zygmund Operators and Their Commutators with BMO Functions in Herz-Morrey Spaces with Variable Smoothness and Integrability

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Communications in Mathematical Research 2017年第3期33卷 238-258页

作者： hu yuan-zhu xu jing-shi ji you-qing School of Mathematics and Statistics Hainan Normal University Haikou 571158 不详

In this paper, we obtain that multilinear Calderón-Zygmund operators and their commutators with BMO functions are bounded on products of Herz-Morrey spaces with variable smoothness and integrability. The vector-value... 详细信息

关键词： multilinear Calderón-Zygmund operator variable exponent Herz-Morrey space vector valued estimate

Analysis of gene expression patterns with cDNA microarray during late stage of spermatogenesis in mice

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Chinese Science Bulletin 2002年第24期47卷 2075-2079页

作者： YU Zuoren GUAN Jikui GE Yehua MA jing GUO Rui LI Sai xue Shepu HAN Daishu Department of Cell Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100005China

The differentiation process of round spermat-ids to spermatozoa during the late stage of spermatogenesis is called spermiogenesis. To explore spermiogenesis-related genes, cDNA microarray was used to study expression patterns of 1176 genes in pachytene spermatocytes, round spermatids and elongating spermatids of Balb/c mice. The results showed that 208 genes were detected in all the three cell types. Most of them were down-regulated from pachytene spermatocytes to round spermatids and elongating spermatids. However, up-regulation of 7 genes expression in round spermatids and 3 genes in elongating spermatids were found. Expression of 7 differentially expressed genes in cDNA arrays was further confirmed by semi-quantitative RT-PCR study. The RT-PCR results indicated that the expression of 6 genes was consistent with that in cDNA arrays, only one gene did not show differential expression by RT-PCR. These results may provide important clues for studying of expression, regulation, and function of

关键词： spermatogenesis spermiogenesis cDNA microarray gene expression pattern RT-PCR.

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吸入式麻醉剂在精神科的应用研究进展

神经疾病与精神卫生 2024年第9期24卷 671-674页

作者：程雪赵新民廖春梅黄敏胡舒史战明重庆市精神卫生中心老年科 401147 重庆市江北区精神卫生中心精神科 401346

对于拒绝静脉麻醉、过于兴奋激动不配合静脉麻醉、孕期妇女不适宜进行静脉麻醉的严重精神障碍患者,吸入式麻醉剂可以替代静脉麻醉应用于无抽搐电休克治疗(MECT)中,此外,吸入式麻醉剂七氟烷、异氟烷也有独立的抗抑郁作用。本文就七氟烷... 详细信息

对于拒绝静脉麻醉、过于兴奋激动不配合静脉麻醉、孕期妇女不适宜进行静脉麻醉的严重精神障碍患者,吸入式麻醉剂可以替代静脉麻醉应用于无抽搐电休克治疗(MECT)中,此外,吸入式麻醉剂七氟烷、异氟烷也有独立的抗抑郁作用。本文就七氟烷、恩氟烷、异氟烷在精神科的应用研究进行综述,为吸入式麻醉剂临床应用提供参考。

关键词：麻醉药,吸入恩氟烷无抽搐电休克治疗七氟烷异氟烷综述

机器人手术系统辅助内固定手术治疗股骨颈骨折的效果及术后感染相关因素分析

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中国医药 2024年第8期19卷 1203-1207页

作者：党海峰杨超郝治龙樊俊俊薛宝宝石磊空军军医大学第一附属医院骨科西安710032

目的研究机器人手术系统辅助内固定手术治疗股骨颈骨折的效果并分析术后感染的相关因素。方法选取2019年4月至2022年4月空军军医大学第一附属医院收治的93例股骨颈骨折患者。完全随机分为对照组(46例)和观察组(47例)。对照组行传统徒手... 详细信息

目的研究机器人手术系统辅助内固定手术治疗股骨颈骨折的效果并分析术后感染的相关因素。方法选取2019年4月至2022年4月空军军医大学第一附属医院收治的93例股骨颈骨折患者。完全随机分为对照组(46例)和观察组(47例)。对照组行传统徒手定位方式内固定手术,观察组行机器人手术系统辅助内固定手术。比较2组手术相关指标、空心钉与股骨颈轴线夹角、骨折愈合时间、Harris髋关节功能评分及并发症发生情况。根据术后感染情况分为感染组与未感染组,采用Logistic回归模型分析术后感染的影响因素。结果观察组术中透视时间、术中出血量及导针植入次数均短于/少于对照组[(14±5)s比(21±5)s、(8.0±3.5)ml比(10.1±2.4)ml、(4.8±0.8)次比(11.8±2.4)次](均P0.05)。患者术后发生感染34例,未感染59例。感染组年龄≥60岁、术前贫血、围手术期异体输血比例、手术时间、引流管留置时间均大于/长于未感染组(均P<0.05)。Logistic回归分析结果显示,术前贫血、围手术期异体输血、手术时间及引流管留置时间为股骨颈骨折患者术后感染的独立影响因素(均P<0.05)。结论机器人手术系统辅助内固定手术用于股骨颈骨折治疗,能更精准置入空心钉,改善患者预后。围手术期密切关注贫血、异体输血等可减少术后感染。

关键词：股骨颈骨折机器人内固定空心钉术后感染

Hemoglobin Fukuoka caused unexpected hemoglobin A1c results: A case report

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World Journal of Clinical Cases 2021年第20期9卷 5568-5574页

作者： xue-Ping Lin Qiu-Rong Yuan shi-Qiong Niu Xi Jiang Zhi-Kun Wu Zhao-Fan Luo Department of Clinical Medical Laboratory The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhen 518107Guangdong ProvinceChina

BACKGROUND Glycated hemoglobin(Hb)(HbA1c)is an indicator that is used to diagnose and monitor the treatment of *** factors can affect the detection of *** of the most important of these factors is the Hb ***,we report a rare Hb variant and evaluate its effect on *** SUMMARY A 35-year-old man was suspected of harboring an Hb variant following the measurement of HbA1c with the Variant II Turbo 2.0 Hb detection system during a routine ***,we used the Arkray HA-8160 and ARCHITECT c4000 system to reanalyze ***,the Hb variant was detected with a Capillary2FP analyzer that operates on the principle of capillary *** also used gene sequencing to investigate the mutation *** value of HbA1c detected with the Variant II Turbo 2.0 system was 52.7%.However,the Arkray HA-8160 system did not display a result while the ARCHITECT c16000 system showed a result of 5.4%.The Capillary2FP analyzer did not reveal any abnormal Hb ***,gene sequencing identified the presence of a mutation in the Hbβ2 chain[CD2(CAC>TAC),His>Tyr,HBB:c.7C>T];the genotype was Hb *** Hb variants could cause abnormal HbA1c *** patients with Hb variants,different methods should be used to detect HbA1c.

关键词： Hemoglobin Fukuoka Hemoglobin A1c Hemoglobin variant High-performance liquid chromatography Enzymatic method Case report

miR-146a调控TLRs信号通路对类风湿关节炎患者外周血单个核细胞的影响

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风湿病与关节炎 2024年第6期13卷 1-4,10页

作者：闫慧明刘河红张雪张丽霞闫师薛一萍孙英梅内蒙古科技大学包头医学院第二附属医院内蒙古包头014030

目的:观察miR-146a调控TLRs信号通路对活动期类风湿关节炎患者外周血单个核细胞的影响。方法:选取20例活动期类风湿关节炎患者,对患者外周血单个核细胞分离培养,分为LPS组和LPS+miR-146a组;同时选取10例健康体检者为健康对照组。采用MT... 详细信息

目的:观察miR-146a调控TLRs信号通路对活动期类风湿关节炎患者外周血单个核细胞的影响。方法:选取20例活动期类风湿关节炎患者,对患者外周血单个核细胞分离培养,分为LPS组和LPS+miR-146a组;同时选取10例健康体检者为健康对照组。采用MTT法测定吸光度,比较外周血单个核细胞变化,检测外周血单个核细胞的凋亡情况。RT-PCR法检测外周血单个核细胞miR-146a、Toll样受体2(TLR2)、髓样分化因子88(MyD88)mRNA表达。Western blot法检测外周血单个核细胞miR-146a、TLR2、MyD88蛋白表达。结果:LPS组较健康对照组和LPS+miR-146a组外周血单个核细胞TLR2表达明显升高(P<0.05);LPS组较健康对照组和LPS+miR-146a组外周血单个核细胞中miR-146a、TLR2、MyD88 mRNA表达明显升高(P<0.05);LPS组较健康对照组和LPS+miR-146a组外周血单个核细胞miR-146a、TLR2、MyD88蛋白表达明显升高(P<0.05)。结论:高表达miR-146a可能通过依赖TLR2/MyD88信号通路,抑制活动期类风湿关节炎患者外周血单个核细胞中TLR2、MyD88表达,减轻炎症反应。

关键词：类风湿关节炎外周血单个核细胞 miR-146 Toll样受体2 髓样分化因子88

Arterial chemoembolization for hepatocellular carcinoma

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World Journal of Gastroenterology 1998年第1期4卷 38-42页

作者： FAN Jian TEN Gao-jing HE shi-Cheng GUO Jin-He YANG Dong-Pei WENG Guo-Ying Department of General Surgery First Affil. Hosp. Nanjing Rlwy. M. Nanjing 210009 Jiangsu Province China Nanjing Railway Medical College China Department of General Surgery First Affil. Hosp. Nanjing Rlwy. M. 87 Dingjiaqiao Road Nanjing 210009 Jiangsu Province China

IM To study the therapeutic effects of transcatheter arterial threesegment chemoembolization for hepatocellular carcinoma (HCC).METHODS According to the anatomy of vessels, the tumor capillary networks, muscular arterioles and feeding arteries were successively occluded using lipiodol ultrafluid (LUF), sinobufagin microsphere (SBMs) and particles of gelatin sponge (PGS). In this series of 80 cases, therapeutic effects were evaluated in 76 cases.RESULTS There were 22 cases (289%) with partial response and 41 (539%) with minor response in the 76 evaluated patients. The 6month, 1year, 2year and 3year survival rates were 974%, 868%, 461% and 276% respectively.CONCLUSION This regimen was a rational chemoembolization method for HCC patients.

关键词： Liver neoplasm/therapy Lipiodol sinobufagin microsphere gelatin sponge chemoembolization,therapeutic

An efficient and DoS-resistant user authentication scheme for two-tiered wireless sensor networks

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第7期12卷 550-560页

作者： Rong FAN ,Dao-jing HE ,xue-zeng PAN,Ling-di PING (School of Computer Science and Technology,Zhejiang University,Hangzhou 310027,China) School of Computer Science and Technology Zhejiang University Hangzhou China

Wireless sensor networks (WSNs) are vulnerable to security attacks due to their deployment and resource *** that most large-scale WSNs follow a two-tiered architecture,we propose an efficient and denial-of-service (DoS)-resistant user authentication scheme for two-tiered *** proposed approach reduces the computational load,since it performs only simple operations,such as exclusive-OR and a one-way hash *** feature is more suitable for the resource-limited sensor nodes and mobile *** it is unnecessary for master nodes to forward login request messages to the base station,or maintain a long user *** addition,pseudonym identity is introduced to preserve user *** clever design,our proposed scheme can prevent smart card ***,security and performance analysis demonstrates the effectiveness and robustness of the proposed scheme.

关键词： User authentication User anonymity Smart card Two-tiered Wireless sensor network (WSN)

Development and Validation of a Nomogram for 90-day Outcome in Patients with Hepatitis B Virus-related Acute-on-chronic Liver Failure

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Journal of Clinical and Translational Hepatology 2022年第3期10卷 458-466页

作者： Jun Yang Ran xue jing Wu Lin Jia Juan Li Hongwei Yu Yueke Zhu Jinling Dong Qinghua Meng Department of Critical Care Medicine of Liver Disease Beijing Youan HospitalCapital Medical UniversityBeijingChina Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Phase I Clinical TrialPeking University Cancer Hospital&InstituteBeijingChina

Background and Aims:It is challenging to predict the 90-day outcomes of patients infected with hepatitis B virus-related acute-on-chronic liver failure(HBV-ACLF)via prevailing predictive *** study aimed to develop an innovative model to enhance the analytical efficacy of 90-day mortality in ***:In this study,149 HBV-ACLF patients were evaluated by constructing a death risk prediction *** resampling and an independent validation cohort comprising 31 patients from June 2019 to February 2020 were assessed for model ***:The nomogram was constructed by entering and identifying five factors age,total bilirubin,prothrombin activity(PTA),lymphocyte(L)%,and monocyte(M)%.Healthy refinement was achieved from the nomogram analysis,where the area under the receiver operating characteristic curve was 0.864 for the training cohort and 0.874 was achieved for the validation *** was admirable concordance between the predicted and true results in the equilibrium *** decision curve assessment revealed the useful clinical application of the ***:We constructed an innovative nomogram and validated it for the prediction of 90-day HBV-ACLF patient *** model might help develop optimized treatment protocol recommendations for HBV-ACLF patients。

关键词： Acute-on-chronic hepatitis B liver failure MELD Nomogram