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A Polyvinyl Alcohol/Acrylamide Hydrogel with Enhanced Mechanical Properties Promotes Full-Thickness Skin Defect Healing by Regulating Immunomodulation and Angiogenesis Through Paracrine Secretion

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Engineering 2024年第6期37卷 138-151页

作者： Peng Wang Liping Qian Huixin Liang Jianhao Huang jing Jin Chunmei xie Bin Xue Jiancheng Lai Yibo Zhang Lifeng jiang Lan Li Qing jiang State Key Laboratory of Pharmaceutical Biotechnology Division of Sports Medicine and Adult Reconstructive SurgeryDepartment of Orthopedic SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing UniversityNanjing 210008China jiangsu Engineering Research Center for 3D Bioprinting Nanjing 210008China Institute of Medical 3D Printing Nanjing UniversityNanjing 210093China Centre for Experimental Animals Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing UniversityNanjing 210008China College of Aeroplane Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China National Laboratory of Solid State Microstructures Department of PhysicsNanjing UniversityNanjing 210093China Department of Chemical Engineering Stanford UniversityStanfordCA 94305USA Department of Orthopedic Surgery The Second Affiliated Hospital Zhejiang University School of MedicineOrthopedic Research Institute of Zhejiang UniversityKey Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang ProvinceHangzhou 310009China

Hydrogel-based tissue-engineered skin has attracted increased attention due to its potential to restore the structural integrity and functionality of ***,the mechanical properties of hydrogel scaffolds and natural skin are substantially ***,we developed a polyvinyl alcohol(PVA)/acrylamide based interpenetrating network(IPN)hydrogel that was surface modified with polydopamine(PDA)and termed *** Dopa-gel exhibited mechanical properties similar to native skin tissue and a superior ability to modulate paracrine ***,a tough scaffold with tensile resistance was fabricated using this hydrogel by three-dimensional *** results showed that the interpenetration of PVA,alginate,and polyacrylamide networks notably enhanced the mechanical properties of the *** modification with PDA endowed the hydrogels with increased secretion of immunomodulatory and proangiogenic *** an in vivo model,Dopa-gel treatment accelerated wound closure,increased vascularization,and promoted a shift in macrophages from a proinflammatory M1 phenotype to a prohealing and anti-inflammatory M2 phenotype within the wound ***,the focal adhesion kinase(FAK)/extracellular signal-related kinase(ERK)signaling pathway may mediate the promotion of skin defect healing by increasing paracrine secretion via the ***,proangiogenic factors can be induced through Rho-associated kinase-2(ROCK-2)/vascular endothelial growth factor(VEGF)-mediated paracrine secretion under tensile stress *** together,these findings suggest that the multifunctional Dopa-gel,which has good mechanical properties similar to those of native skin tissue and enhanced immunomodulatory and angiogenic properties,is a promising scaffold for skin tissue regeneration.

关键词： Polyvinyl alcohol/acrylamide hydrogel Mechanical property enhancement Paracrine effect Skin regeneration Signaling pathways

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Gelfand-Kirillov Dimension and Reducibility of Scalar Generalized Verma Modules for Classical Lie Algebras

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Acta Mathematica Sinica,English Series 2024年第3期40卷 658-706页

作者： Zhan Qiang BAI jing jiang School of Mathematical Sciences Soochow UniversitySuzhou 215006P.R.China E-mail:zqbai@*** jjsd6514@***

Let g be a classical complex simple Lie algebra and q be a parabolic *** M be a generalized Verma module induced from a one dimensional representation of *** M is called a scalar generalized Verma *** this paper,we will determine the reducibility of scalar generalized Verma modules associated to maximal parabolic subalgebras by computing explicitly the Gelfand-Kirillov dimension of the corresponding highest weight modules.

关键词： Generalized Verma module Gelfand-Kirillov dimension Young tableau

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Selective photosynthesis of Z-olefins through crystalline metal-organic cage-initiated expeditious cascade reactions

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Carbon Energy 2024年第3期6卷 118-131页

作者： Jia-Ni Lu Yunze Huang Yuan-Sheng Xia Long-Zhang Dong Lei Zhang jing-jing Liu Lan-Gui xie jiang Liu Ya-Qian Lan jiangsu Key Laboratory of New Power Batteries School of Chemistry and Materials ScienceJiangsu Collaborative Innovation Centre of Biomedical Functional MaterialsNanjing Normal UniversityNanjingChina School of Chemistry South China Normal UniversityGuangzhouChina

The semi-hydrogenation of alkyne to form Z-olefins with high conversion and high selectivity is still a huge challenge in the chemical ***,flammable and explosive hydrogen as the common hydrogen source of this reaction increases the cost and danger of industrial ***,we connect the photocatalytic hydrogen evolution reaction and the semihydrogenation reaction of alkynes in series and successfully realize the high selective production of Z-alkenes using low-cost,safe,and green water as the proton *** the cascade reaction,a series of isomorphic metal–organic cage catalysts(Co_(x)Zn_(8−x)L_(6),x=0,3,4,5,and 8)are designed and synthesized to improve the yield of the photocatalytic hydrogen *** them,Co_(5)Zn_(3)L_(6) shows the highest photocatalytic activity,with a H_(2) generation rate of 8.81 mmol g^(−1) h^(−1).Then,Co_(5)Zn_(3)L_(6) is further applied in the above tandem reaction to efficiently reduce alkynes to Z-alkenes under ambient conditions,which can reach high conversion of>98%and high selectivity of>99%,and maintain original catalytic activity after multiple ***“one-pot”tandem reaction can achieve a highly selective and safe stepwise conversion from water into hydrogen into Z-olefins under mild reaction conditions.

关键词： alkyne semi-hydrogenation hydrogen evolution reaction metal-organic cages photocatalysis Z-olefins

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Spatio-temporal variability of surface chlorophyll a in the Yellow Sea and the East China Sea based on reconstructions of satellite data of 2001-2020

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Journal of Oceanology and Limnology 2024年第2期42卷 390-407页

作者： Weichen xie Tao WANG Wensheng jiang Key Laboratory of Marine Environment and Ecology Ocean University of ChinaQingdao 266100China College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100China

Chlorophyll-a(Chl-a)concentration is a primary indicator for marine environmental *** spatio-temporal variations of sea surface Chl-a concentration in the Yellow Sea(YS)and the East China Sea(ECS)in 2001-2020 were investigated by reconstructing the MODIS Level 3 products with the data interpolation empirical orthogonal function(DINEOF)*** reconstructed results by interpolating the combined MODIS daily+8-day datasets were found better than those merely by interpolating daily or 8-day ***-a concentration in the YS and the ECS reached its maximum in spring,with blooms occurring,decreased in summer and autumn,and increased in late autumn and early *** performing empirical orthogonal function(EOF)decomposition of the reconstructed data fields and correlation analysis with several potential environmental factors,we found that the sea surface temperature(SST)plays a significant role in the seasonal variation of Chl a,especially during spring and *** increase of SST in spring and the upper-layer nutrients mixed up during the last winter might favor the occurrence of spring *** high sea surface temperature(SST)throughout the summer would strengthen the vertical stratification and prevent nutrients supply from deep water,resulting in low surface Chl-a *** sea surface Chl-a concentration in the YS was found decreased significantly from 2012 to 2020,which was possibly related to the Pacific Decadal Oscillation(PDO).

关键词： chlorophyll a(Chl a) data interpolation empirical orthogonal function(DINEOF) empirical orthogonal function(EOF)analysis Yellow Sea East China Sea

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A Robust Framework for Multimodal Sentiment Analysis with Noisy Labels Generated from Distributed Data Annotation

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2965-2984页

作者： Kai jiang Bin Cao jing Fan School of Computer Science and Technology Zhejiang University of TechnologyHangzhou310023China

Multimodal sentiment analysis utilizes multimodal data such as text,facial expressions and voice to detect people’s *** the advent of distributed data collection and annotation,we can easily obtain and share such multimodal ***,due to professional discrepancies among annotators and lax quality control,noisy labels might be *** research suggests that deep neural networks(DNNs)will overfit noisy labels,leading to the poor performance of the *** address this challenging problem,we present a Multimodal Robust Meta Learning framework(MRML)for multimodal sentiment analysis to resist noisy labels and correlate distinct modalities ***,we propose a two-layer fusion net to deeply fuse different modalities and improve the quality of the multimodal data features for label correction and network ***,a multiple meta-learner(label corrector)strategy is proposed to enhance the label correction approach and prevent models from overfitting to noisy *** conducted experiments on three popular multimodal datasets to verify the superiority of ourmethod by comparing it with four baselines.

关键词： Distributed data collection multimodal sentiment analysis meta learning learn with noisy labels

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Joint Optimization of Resource Allocation and Trajectory Based on User Trajectory for UAV-Assisted Backscatter Communication System

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China Communications 2024年第2期21卷 197-209页

作者： Peizhong xie Junjie jiang Ting Li Yin Lu School of Communication and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing 210003China Key Lab of Broadband Wireless Communication and Sensor Network Technology(Nanjing University of Posts and Telecommunications) Ministry of EducationNanjing 210003China

The Backscatter communication has gained widespread attention from academia and industry in recent years. In this paper, A method of resource allocation and trajectory optimization is proposed for UAV-assisted backscatter communication based on user trajectory. This paper will establish an optimization problem of jointly optimizing the UAV trajectories, UAV transmission power and BD scheduling based on the large-scale channel state signals estimated in advance of the known user trajectories, taking into account the constraints of BD data and working energy consumption, to maximize the energy efficiency of the system. The problem is a non-convex optimization problem in fractional form, and there is nonlinear coupling between optimization *** iterative algorithm is proposed based on Dinkelbach algorithm, block coordinate descent method and continuous convex optimization technology. First, the objective function is converted into a non-fractional programming problem based on Dinkelbach method,and then the block coordinate descent method is used to decompose the original complex problem into three independent sub-problems. Finally, the successive convex approximation method is used to solve the trajectory optimization sub-problem. The simulation results show that the proposed scheme and algorithm have obvious energy efficiency gains compared with the comparison scheme.

关键词： energy efficiency joint optimization UAV-assisted backscatter communication user trajectory

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Hydrochemical characteristics and the ecological effect of algal carbonic anhydrase in carbon cycle in the Taiyuan section of Fenhe River

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Journal of Oceanology and Limnology 2024年第5期42卷 1507-1524页

作者： jing YANG Xin LI Shulian xie Jia FENG Shanxi Key Laboratory of Yuncheng Salt Lake Ecological Protection and Resource Utilization College of Life SciencesYuncheng UniversityYuncheng 044000China School of Life Science Shanxi UniversityTaiyuan 030006China

Water scarcity and pollution pose a threat to the sustainable development of cities and ***,it is crucial to analyze the hydrochemical characteristics and carbon dynamics of waterdeficient *** the Taiyuan section of Fenhe River as the research object,we systematically explored the hydrochemical characteristics of surface water and its evolutionary processes,as well as the ecological effect of algal carbonic anhydrase in carbon cycle using the hydrochemical evolution method and correlation *** ternary diagram demonstrates that the main water chemical type in Fenhe River was SO^(2-)_(4)·Cl^(-)-Na^(+).The Gibbs and end-member diagrams of each ion display that the chemical composition of surface water was mainly controlled by silicate *** chemical ions originated mainly from dissolution of some minerals,such as plagioclase,halite,dolomite,calcite,and *** diatoms had a lower CO_(2)requirement because they exhibited a higher abundance at a lower partial pressure of CO_(2)(p CO_(2)).However,high CO_(2)concentration had a positive effect on cyanobacteria,which reduced the active transport of HCO_(3)^(-),saved the energy needed for this part of active transport,and indirectly improved the overall photosynthetic efficiency of *** anhydrase(CA)activity was significantly negatively correlated with p CO_(2)and positively correlated with HCO_(3)^(-)concentration,indicating that CA in water promoted the conversion of CO_(2)to HCO_(3)^(-).The HCO_(3)^(-)generated from this process continued to participate in the erosion of silicate rocks,sequestering CO_(2)in the form of Ca CO_(3),which has a non-negligible impact on the carbon sink in the Fenhe *** consequences may have important implications for the biogeochemical cycling occurring in urban water.

关键词： hydrochemistry inorganic carbon phytoplankton community carbonic anhydrase Fenhe River

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Multilayer polyethylene separator with enhanced thermal properties for safe lithium-ion batteries Author links open overlay panel

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Particuology 2024年第8期91卷 29-37页

作者： Ying jiang Chen Sun Feilong Dong Haiming xie Liqun Sun National&Local United Engineering Laboratory for Power Battery Department of ChemistryNortheast Normal UniversityChangchun130024China

The separator plays an important part in battery safety and *** separators are widely used in commercial Lithium-ion batteries(LIBs),owing to their excellent properties,but they suffer from serious thermal shrinkage and poor electrolyte ***,a multilayer separator(ASPESA)is developed by coating two thin layers of low-density polyethylene(LDPE)and Al_(2)O_(3)on both sides of a polyethylene membrane using a facile and environmentally friendly casting *** ASPESA separator demonstrates a shutdown function at 120℃and shows enhanced thermal stability under 185℃,with a small thermal shrinkage of 1%.Meanwhile,the LDPE and Al_(2)O_(3)layers can improve the electrolyte wettability and electrolyte uptake(407.23%).The multilayer ASPESA separator delivers an excellent cycle performance in LiFePO_(4)||Li cells with a discharge capacity of 144.5 mAh g^(-1)after 900 cycles,with a high-capacity retention of 98.9%(compared to the 5th cycle).Therefore,the multilayer ASPESA separator has great utilization potential as a high-safety separator in LIBs.

关键词： Low-density polyethylene microspheres Al_(2)O_(3)particles Thermal shutdown High safety Lithium-ionbatteries

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Experimental investigation about the incipient velocity of spherical particles on a hemispherical bed surface

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Particuology 2024年第5期88卷 49-61页

作者： Chuannan Li Jie Chen Changbo jiang xie Li Zhiyuan Wu School of Hydraulic and Environmental Engineering Changsha University of Science & TechnologyChangsha 410114China Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province Changsha 410114China Key Laboratory of Water-Sediment Sciences and Water Disaster Prevention of Hunan Province Changsha 410114China

The sediment particles play a huge role in shaping the bed load *** this research,240 water-tunnel experiments are carried out to investigate the incipient velocity of the observation particles in two particle *** accurately predict the incipient velocity of the observation particles,the equation is conceived by the rolling instability *** incipient velocity equations and experimental data are used to analyze the trend of dispersive pressure and the effect of arrangement position on *** find that it is appropriate to choose the coefficient of drag as 0.261 and the coefficient of lift as 0.198 for the incipient velocity equation of spherical particles on the hemispherical bed ***,the dispersive pressure is closely related to the flow state,particle size,and particle arrangement,which leads to the incipient velocity of the observation particle being at a minimum when the interference particle angle is 45°.Finally,the particle spacing and the projected area changed with the arrangements,directly affecting the incipient velocity of the observed *** analysis of four aspects for the coefficients,dispersive pressure,different particle spacing,and projected area will facilitate the prediction of particle incipient velocity,especially on hemispherical beds.

关键词： Hemispherical bed surface Observed particle Interference particle Dispersive pressure Incipient velocity

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Output Feedback Stabilization of High-Order Nonlinear Time-Delay Systems With Low-Order and High-Order Nonlinearities

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1304-1306页

作者： Meng-Meng jiang Kemei Zhang Xue-Jun xie School of Mathematics Science Liaocheng UniversityLiaocheng 252059China School of Mathematics Science Qufu Normal UniversityQufu 273165China Institute of Automation Qufu Normal UniversityQufu 273165China

Dear Editor,to This letter deals with the output feedback stabilization of a class of high-order nonlinear time-delay systems with more general low-order and high-order *** constructing reduced-order observer,based on homogeneous domination theory together with the adding a power integrator method,an output feedback controller is developed guarantee the equilibrium of the closed system globally uniformly asymptotically stable.

关键词： Nonlinear stabilization guarantee

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