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Comprehensive and personalized approach is a critical area for developing remote cardiac rehabilitation programs

World Journal of Clinical Cases 2024年第12期12卷 2009-2015页

作者： Garyfallia Pepera Varsamo Antoniou jing jing su Rose Lin Ladislav Batalik Clinical Exercise Physiology and Rehabilitation Research Laboratory Department of PhysiotherapyFaculty of Health SciencesUniversity of ThessalyLamia GR35100Greece School of Nursing The Hong Kong Polytechnic UniversityHong Kong 999077China University of Rochester School of Nursing New YorkNY 14602United States Department of Rehabilitation University Hospital BrnoBrno 62500Czech Republic Department of Public Health Faculty of MedicineMasaryk UniversityBrno 62500Czech Republic

In the evolving landscape of cardiac rehabilitation(CR),adopting digital technologies,including synchronous/real-time digital interventions and smart applications,has emerged as a transformative *** technologies offer realtime health data access,continuous vital sign monitoring,and personalized educational enhanced patient self-management and *** their potential benefits,challenges and limitations exist,necessitating careful ***/real-time digital CR involves remote,two-way audiovisual communication,addressing issues of accessibility and promoting home-based *** applications extend beyond traditional healthcare,providing real-time health data and fostering patient *** devices and mobile apps enable continuous monitoring,tracking of rehabilitation outcomes,and facilitate lifestyle modifications crucial for cardiac health *** digital CR progresses,ensuring patient access,equitable implementation,and addressing the digital divide becomes *** intelligence holds promise in the early detection of cardiac events and tailoring patient-specific CR ***,challenges such as digital literacy,data privacy,and security must be addressed to ensure inclusive ***,the shift toward digital CR raises concerns about cost,safety,and potential depersonalization of therapeutic relationships.A transformative shift towards technologically enabled CR necessitates further research,focusing not only on technological advancements but also on customization to meet diverse patient *** challenges related to cost,safety,data security,and potential depersonalization is crucial for the widespread adoption of digital *** studies should explore integrating moral values into digital therapeutic relationships and ensure that digital CR is accessible,equitable,and seamlessly integrated into routine cardiac *** frameworks that accommodate

关键词： Cardiac rehabilitation Digital approaches Remote care Equity in technology access Synchronous/real-time interventions Digital innovation in healthcare

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Factors affecting meibomian gland area loss in symptomatic adults

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1036-1041页

作者： Si-Cheng Ding jing-jing su Qing Zhan Jiao-Man Wang Fang Zheng Xu-Xuan Fang Dan Cheng Ping Guo The Second Clinical Medical College Jinan UniversityShenzhen 518000Guangdong ProvinceChina Shenzhen Eye Hospital Jinan UniversityShenzhen Eye InstituteShenzhen 518040Guangdong ProvinceChina Department of Ophthalmology Jinzhou Medical UniversityJinzhou 121000Liaoning ProvinceChina

AIM:To characterize the distribution of meibomian gland(MG)area loss(MGL)and its relationship with demographic characteristics,mites,and ***:This retrospective observational study included patients who visited the Dry Eye Clinic of Shenzhen Eye Hospital between June 2020 and August *** patient characteristics,ocular symptoms,Demodex test results of the eyelid edges,and the results of a comprehensive ocular surface analysis were *** was analyzed using Image J ***:This study enrolled 1204 outpatients aged 20-80(40.70±13.44)y,including 357 males(29.65%)and 847 females(70.35%).The patients were classified into mild(n=155;12.87%),moderate(n=795;66.03%),severe(n=206;17.11%),and extremely severe(n=48;3.99%)MGL *** was significantly larger in female than in male(P=0.006).The degree of MGL also significantly differed in age(P<0.001)and the more numbers of mites with severity(P<0.001).Multivariate disordered multinomial logistic regression analysis identified that female sex,older age,secretory symptoms,and a large number of mites were risk factors for MGL(P<0.05).CONCLUSION:Patients with MGL are more likely to be older,female,more numbers of mites,and increased secretion.

关键词： meibomianglands aging sex symptomatology Demodex

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On the Infinite-Dimensional Modular Lie superalgebras of O-Type

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Algebra Colloquium 2024年第2期31卷 347-360页

作者： Xiaoning Xu jing Zhao Yucai su School of Mathematics and Statistics Liaoning UniversityShenyang 110036China 不详

The natural filtrations of infinite-dimensional Lie superalgebras of O-type over a field of positive characteristic are proved to be invariant under automorphisms by studying ad-nilpotent *** observe that two Lie superalgebras of O-type are isomorphic if and only if the integers in the definition of these Lie superalgebras are ***,all the Lie superalgebras of O-type are classified in the sense of isomorphism.

关键词： filtration isomorphism classification

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A versatile model with three-dimensional triangular lattice for unconventional transport and various topological effects

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National Science Review 2024年第1期11卷 204-214页

作者： jing-Yang You Gang su Yuan Ping Feng Department of Physics National University of Singapore Kavli Institute for Theoretical Sciences and CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of Sciences Centre for Advanced 2D Materials National University of Singapore

The finite Berry curvature in topological materials can induce many subtle phenomena, such as the anomalous Hall effect(AHE), spin Hall effect(SHE), anomalous Nernst effect(ANE), non-linear Hall effect(NLHE) and bulk photovoltaic effects. To explore these novel physics as well as their connection and coupling, a precise and effective model should be developed. Here, we propose such a versatile model—a 3D triangular lattice with alternating hopping parameters, which can yield various topological phases,including kagome bands, triply degenerate fermions, double Weyl semimetals and so on. We reveal that this special lattice can present unconventional transport due to its unique topological surface states and the aforementioned topological phenomena, such as AHE, ANE, NLHE and the topological photocurrent effect. In addition, we also provide a number of material candidates that have been synthesized experimentally with this lattice, and discuss two materials, including a non-magnetic triangular system for SHE, NLHE and the shift current, and a ferromagnetic triangular lattice for AHE and ANE. Our work provides an excellent platform, including both the model and materials, for the study of Berry-curvature-related physics.

关键词： three-dimensional triangular lattice different topological phases various topological effects Berry curvature

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The main strategies for soil pollution apportionment:A review of the numerical methods

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Journal of Environmental Sciences 2024年第2期136卷 95-109页

作者： Bin Shi jing Meng TieyuWang Qianqian Li Qifan Zhang Guijin su Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Guangdong Provincial Key Laboratory of Marine Disaster Prediction and Prevention Shantou UniversityShantou 515063China

Nowadays,a large number of compounds with different physical and chemical properties have been determined in *** behaviors and source identification of pollutants in soil are the foundation of soil pollution *** and quantitative analysis of potential pollution sources are the prerequisites for its prevention and *** efforts have made to develop methods for identifying the sources of soil *** efforts have involved the measurement of source and receptor parameters and the analysis of their relationships via numerical statistics *** have comprehensively reviewed the progress made in the development of source apportionment methodologies to date and present our *** numerical methods,such as spatial geostatistics analysis,receptor models,and machine learning methods are addressed in *** most cases,however,the effectiveness of any single approach for source apportionment remains *** multiple methods to address soil quality problems can reduce uncertainty about the sources of soil *** review also constructively highlights the key strategies of combining mathematical models with the assessment of chemical profiles to provide more accurate source *** review intends to provide a comprehensive summary of source apportionment methodologies to help promote further development.

关键词： Soil pollutants Source attribution Methodologies Chemical profiles Mathematical models

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Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1483-1493页

作者： jing Jin Yurou Wang Yueqin Liu subrata Chakrabarti Zhaoliang su International Genome Center Jiangsu UniversityZhenjiang 212013China Institute for Medical Immunology Jiangsu UniversityZhenjiang 212013China Center Laboratory the Fourth People's Hospital of ZhenjiangZhenjiang 212008China Department of Pathology and Laboratory Medicine Western UniversityLondonOntario N6A 5C1Canada

Cardiac resident macrophages (CRMs) are the main population of cardiac immune cells. The role of these cells in regeneration, functional remodeling, and repair after cardiac injury is always the focus of research. However, in recent years, their dynamic changes and contributions in physiological states have a significant attention. CRMs have specific phenotypes and functions in different cardiac chambers or locations of the heart and at different stages. They further show specific differentiation and development processes. The present review will summarize the new progress about the spatiotemporal distribution, potential developmental regulation, and their roles in cardiac development and aging as well as the translational potential of CRMs on cardiac diseases. Of course, the research tools for CRMs, their respective advantages and disadvantages, and key issues on CRMs will further be discussed.

关键词： Cardiac resident macrophages Spatiotemporal distribution Cardiac development Cardiac homeostasis Physiological functions Research tools Clinical translation Transcriptional characteristics

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superconducting,Topological,and Transport Properties of Kagome Metals CsTi_(3)Bi_(5)and RbTi_(3)Bi_(5)

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Research 2024年第2期2023卷 753-762页

作者： Xin-Wei Yi Zheng-Wei Liao jing-Yang You Bo Gu Gang su School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Department of Physics Faculty of ScienceNational University of Singapore117551Singapore Kavli Institute for Theoretical Sciences and CAS Center for Excellence in Topological Quantum ComputationUniversity of Chinese Academy of SciencesBeijing 100190China

The recently discovered ATi_(3)Bi_(5)(A=Cs,Rb)exhibit intriguing quantum phenomena including superconductivity,electronic nematicity,and abundant topological ***_(3)Bi_(5)present promising platforms for studying kagome superconductivity,band topology,and charge orders in parallel with *** this work,we comprehensively analyze various properties of ATi_(3)Bi_(5)covering superconductivity under pressure and doping,band topology under pressure,thermal conductivity,heat capacity,electrical resistance,and spin Hall conductivity(SHC)using first-principles *** superconducting transition temperature(Tc)of CsTi_(3)Bi_(5)and RbTi_(3)Bi_(5)at ambient pressure are about 1.85 and 1.92 *** subject to pressure,Tc of CsTi_(3)Bi_(5)exhibits a special valley and dome shape,which arises from quasi-two-dimensional compression to three-dimensional isotropic compression within the context of an overall decreasing ***,Tc of RbTi_(3)Bi_(5)can be effectively enhanced up to 3.09 K by tuning the kagome van Hove singularities(VHSs)and flat band through *** can also induce abundant topological surface states at the Fermi energy(EF)and tune VHSs across ***,our transport calculations are in excellent agreement with recent experiments,confirming the absence of charge density ***,SHC of CsTi_(3)Bi_(5)can reach up to 226h·(e·Ω·cm)^(-1)at *** work provides a timely and detailed analysis of the rich physical properties for ATi_(3)Bi_(5),offering valuable insights for further experimental verifications and investigations in this field.

关键词： doping superconductivity conductivity

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Catalytic degradation of chlorinated volatile organic compounds(CVOCs)over Ce-Mn-Ti composite oxide catalysts

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Journal of Environmental Sciences 2024年第4期138卷 326-338页

作者： Zhiwei Zhou Qianqian Li Guijin su Jiaxin Pang Bohua sun jing Meng Bin Shi Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Environmental Nanotechnology and Health Effects State Key Laboratory of Environmental Chemistry and EcotoxicologyResearch Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China

Developing industrially moldable catalysts with harmonized redox performance and acidity is of great significance for the efficient disposal of chlorinated volatile organic compounds(CVOCs)in actual exhaust ***,commercial TiO_(2),typically used for molding catalysts,was chosen as the carrier to fabricate a series of Ce_(0.02)Mn_(0-0.24)TiO_(x) materials with different Mn doping ratios and employed for chlorobenzene(CB)*** introduction of Mn remarkedly facilitated the synergistic effect of each element via the electron transfer processes:Ce^(3+)+Mn^(4+/3+)■Ce^(4+)+Mn^(3+/2+)and Mn^(4+/3+)+Ti^(4+)■Mn^(3+/2+)+Ti^(3+).These synergistic interactions in Ce_(0.02)Mn_(0.04-0.24)TiO_(x),especially Ce_(0.02)Mn_(0.16)TiO_(x),significantly elevated the active oxygen species,oxygen vacancies and redox properties,endowing the superior catalytic oxidation of *** the Mn doping amount increased to 0.24,a separate Mn_(3)O_(4) phase appeared,which in turn might weaken the synergistic ***,the acidity of Ce_(0.02)Mn_(0.04-0.24)TiO_(x) was decreased with the Mn doping,regulating the balance of redox property and ***,Ce_(0.02)Mn_(0.16)TiO_(x) featured relatively abundant B-acid *** coordinating redox ability and moderate acidity promoted the deep oxidation of CB and RCOOH-intermediates,as well as the rapid desorption of Cl species,thus obtaining sustainable *** comparison,CeTiO_(x) owned the strongest acidity,however,its poor redox property was not sufficient for the timely oxidative decomposition of the easier adsorbed CB,resulting in its rapid *** finding provides a promising strategy for the construction of efficient commercial molding catalysts to decompose the industrial-scale CVOCs.

关键词： Chlorobenzene Ce_(0.02)Mn_(0-0.2)4tiox materials Redox ability Acidity Synergistic interaction

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Lipid nanovehicles overcome barriers to systemic RNA delivery: Lipid components, fabrication methods, and rational design

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Acta Pharmaceutica Sinica B 2024年第2期14卷 579-601页

作者： jing Yan Hao Zhang Guangfeng Li Jiacan su Yan Wei Can Xu Institute of Translational Medicine Shanghai UniversityShanghai 200444China Institute of Medicine Shanghai UniversityShanghai 200444China Department of Orthopedics Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China Department of Orthopedics Shanghai Zhongye HospitalShanghai 200941China Organoid Research Center Shanghai UniversityShanghai 200444China Department of Gastroenterology Changhai HospitalShanghai 200433China

Lipid nanovehicles are currently the most advanced vehicles used for RNA delivery,as demonstrated by the approval of patisiran for amyloidosis therapy in *** illuminate the unique superiority of lipid nanovehicles in RNA delivery,in this review,we first introduce various RNA therapeutics,describe systemic delivery barriers,and explain the lipid components and methods used for lipid nanovehicle ***,we emphasize crucial advances in lipid nanovehicle design for overcoming barriers to systemic RNA ***,the current status and challenges of lipid nanovehicle-based RNA therapeutics in clinical applications are also *** objective is to provide a comprehensive overview showing how to utilize lipid nanovehicles to overcome multiple barriers to systemic RNA delivery,inspiring the development of more high-performance RNA lipid nanovesicles in the future.

关键词： Lipid nanovehicles RNAtherapeutics Barriers to systemicRNA delivery Lipid components Fabricationmethods Lipid nanovehicledesign Extrahepatictissue targeting Organ tropism

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Source apportionment and suitability evaluation of seasonal VOCs contaminants in the soil around a typical refining-chemical integration park in China

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Journal of Environmental Sciences 2024年第3期137卷 651-663页

作者： Xu Zhao jing Meng Qianqian Li Guijin su Qifan Zhang Bin Shi Lingwen Dai Yong Yu Key Laboratory of Environmental Nanotechnology and Health Effects State Key Laboratory of Environmental Chemistry and EcotoxicologyResearch Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China State Environmental Protection Key Laboratory of Quality Control in Environmental Monitoring China National Environmental Monitoring CenterBeijing 100012China

Accurate source apportionment of volatile organic compounds(VOCs)in soil nearby petrochemical industries prevailing globally,is critical for preventing ***,in the process,seasonal effect on contamination pathways and accumulation of soil VOCs is often ***,Yanshan Refining-Chemical Integration Park,including a carpet,refining,synthetic rubber,and two synthetic resin zones,was selected for *** variations resulted in a gradual decrease of 31 VOCs in soil from winter to summer.A method of dry deposition resistance model coupling partitioning coefficient model was created,revealing that dry deposition by gas phase was the primary pathway for VOCs to enter soil in winter and spring,with 100 times higher fux than by particle *** profiles for five zones were built by gas sampling with distinct substance indicators screened,which were used for positive matrix factorization factors *** of the five zones were 14.9%,20.8%,13.6%,22.1%,and 28.6%in winter and 33.4%,12.5%,10.7%,24.9%,and 18.5%in spring,*** variation in the soil sorption capacity of VOCs causes inter-seasonal differences in *** better correlation between dry deposition capacity and soil storage of VOCs made root mean square and mean absolute errors decrease averagely by 8.8%and 5.5%in winter compared to *** study provides new perspectives and methods for the source apportionment of soil VOCs contamination in industrial sites.

关键词： Dry deposition resistance model Positive matrix factorization model Partitioning coefficient model Contamination pathway Source profile

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