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干细胞抗卵巢颗粒细胞衰老的作用机制及进展

中国组织工程研究 2025年第25期29卷 5414-5421页

作者：林美玉赵玺龙高景赵晶阮光萍解放军联勤保障部队第九二〇医院基础医学实验室云南省昆明市650032 干细胞与免疫细胞生物医药技术国家地方联合工程研究中心云南省昆明市650032 云南省细胞治疗技术转化医学重点实验室云南省昆明市650032

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰... 详细信息

背景:干细胞疗法作为一种新兴的治疗手段,有望改善卵巢环境,延缓卵巢颗粒细胞的衰老,为高龄妊娠女性带来新的希望。目的:综述干细胞抗卵巢颗粒细胞衰老的机制及研究进展。方法:检索中国知网和PubMed数据库中关于干细胞抗卵巢颗粒细胞衰老的文献,以“干细胞,卵巢颗粒细胞,衰老”为中文检索词,以“stem cells,ovary granulosa cells,aging”为英文检索词,最终纳入67篇文献进行分析。结果与结论:①总结了5种卵巢颗粒细胞衰老的机制:DNA损伤和修复能力下降、氧化应激、线粒体功能受损、炎症反应、激素水平变化;②整理了当前干细胞治疗卵巢颗粒细胞衰老的5种机制:促进增殖和抑制凋亡、分化潜能及再生能力、分泌因子、抗氧化、抗炎症反应和免疫调节;③目前有多种类型的干细胞可通过多种方式协同治疗卵巢颗粒细胞衰老,干细胞疗法在恢复女性生育能力方面具有广阔前景。

关键词：干细胞卵巢颗粒细胞衰老机制氧化应激抑制凋亡细胞因子抗氧化抗炎症反应

CEO自恋对高管团队成员工作幸福感的影响:CEO谦卑与领导关系认同的作用

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管理工程学报 2025年第2期39卷 206-220页

作者：尹奎赵景宋萌崔国东董念念北京科技大学经济管理学院北京100083 中国人民大学劳动人事学院北京100872 北京工业大学经济管理学院北京100124 山东大学山东省人才发展战略研究院山东济南250100

自恋的CEO在企业中比比皆是,会对员工与组织产生深远影响,而CEO谦卑特质是重要的情境因素。高管团队成员直面CEO并担负着组织内部重要的领导职责,对CEO自恋特质的感知和反应更深刻,其工作幸福感可能也更容易受到影响。基于关系认同理论... 详细信息

自恋的CEO在企业中比比皆是,会对员工与组织产生深远影响,而CEO谦卑特质是重要的情境因素。高管团队成员直面CEO并担负着组织内部重要的领导职责,对CEO自恋特质的感知和反应更深刻,其工作幸福感可能也更容易受到影响。基于关系认同理论,本文构建了一个有中介的调节效应模型,对56位CEO与319位TMT成员的配对数据进行分析,结果表明:CEO自恋对TMT成员工作幸福感产生负向影响;CEO谦卑能够弱化CEO自恋对TMT成员有关领导关系认同的消极影响;TMT成员对领导关系的认同积极影响工作幸福感,中介了CEO谦卑对CEO自恋与TMT成员工作幸福感关系的调节作用。研究拓展了领导自恋影响员工工作幸福感的研究层次与边界情境,揭示了领导关系认同在CEO谦卑弱化CEO自恋消极影响效应中的内在机制,验证了不同领导组合相对于单一领导对领导关系认同与工作幸福感的增强更具有效性,因而丰富了工作幸福感影响因素研究的主体,对CEO的遴选与培训具有潜在的指导意义。

关键词： CEO自恋 CEO谦卑工作幸福感领导关系认同

Effects of Bounding Potential on High-Order Harmonic Generation with H2＋

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Chinese Physics Letters 2010年第6期27卷 89-92页

作者： zhao jing zhao Zeng-Xiu Department of Physics National University of Defense Technology Changsha 410073

We present harmonic spectra from hydrogen molecular ions with different ionization energy Ip. By comparing the recombination matrix element from helium ions and hydrogen molecular ions, we verify that the interference effect in high-order harmonic generation originates from the recombination interference. A numerical study on recombination matrix elements in 1D shows that w = Ek ＋ Ip holds only when an exact continuum wavefunction is used, and the positions of extrema in harmonic spectra can be predicted accurately. We demonstrate that the positions of extrema in harmonic spectra are mainly affected by bounding potential dependence of the recombination interference.

关键词： Recombination Ions Hydrogen Hydrogenation Elements

Plasmon-exciton interaction in colloidally fabricated metal nanoparticlequantum emitter nanostructures

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Nano Research 2019年第9期12卷 2164-2171页

作者： Yi Luo jing zhao Department of Chemistry University of Connecticut55 North Eagleville RoadStorrs06269USA Institute of Materials Science University of Connecticut97 North Eagleville RoadStorrs06269USA

When quantum emitters and plasmonic nanoparticles are in close vicinity,the energy exchange,termed as plasmon-exciton coupling,can make the absorption and emission behavior of the hybrid structure very different from those of the two constituents *** coupling strength between the two constituents highly depends on how the hybrid structure is *** a result,a diverse range of coupling effect arise including plasmon induced fluorescence quenching/enhancing (weak coupling),Fano interference (intermediate coupling),Rabi-splitting and lasing (strong coupling).The emergence of different coupling behavior can be controlled by the different combinations of quantum emitters and plasmonic nanoparticles as well as the spatial arrangement of the individual *** assembly/synthesis methods are essentially delicate strategies that can build the hybrid nanostructures with nanometer precision and allow for large-scale *** this review,we discuss the theoretical models that apply to different coupling behaviors,the optical properties of the hybrid systems,and the advancement of colloidal methods to manipulate the plasmon-exciton in the hybrid *** also provide perspectives on the challenges and future directions of the research in coupled plasmon-exciton nanosystems.

关键词： quantum emitter metal nanoparticles plasm on-exciton coupling colloidal assembly Purcell effect Rabi-splitting

Manipulation of confined structure in alcohol-permselective pervaporation membranes

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Chinese Journal of Chemical Engineering 2017年第11期25卷 1616-1626页

作者： jing zhao Wanqin Jin State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringJiangsu National Synergetic Innovation Center for Advanced MaterialsNanjing Tech UniversityNanjing 210009China

Alcohol-permselectivity pervaporation has been arousing increasingly more attention in bioalcohol production due to the advantages of environmental friendliness, low energy consumption and easy coupling with fermentation process. With the intrinsic feature of larger molecules preferentially permeating and the consequent inferiority in selective diffusion, the development of alcohol-permselective membrane is relatively retarded compared with water-permselective membrane. This review presents the prevalent membrane materials utilized for alcohol-permselective pervaporation and emphatically expatiates the representative and important developments in the past five years from the aspect of tuning confined structure in membranes. In particular, the diverse structure tuning methods are described with the classifications of physical structure and chemical structure. The corresponding structure-performance relationships in alcohol-permselective pervaporation membranes are also analyzed to identify the objective of structure optimization. Furthermore, the tentative perspective on the possible future directions of alcohol-permselective pervaporation membrane is briefly presented.

关键词： Confined structure Pervaporation Membrane Alcohol-permselective

COMPREHENSIVE EVALUATION OF FAULT-TOLERANT PROPERTIES OF REDUNDANT ROBOTS

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Chinese Journal of Mechanical Engineering 2008年第4期21卷 22-26页

作者： zhao jing FENG Dengdian College of Mechanical Engineening and Applied Electronics Technology Beijing University of Technology Beijing 100124 China

When a redundant robot performs a fault-tolerant operation for locked joint failures, its fault tolerant properties should include dexterity and sudden change of joint velocity at the moment of locking failed joints and the dexterity during the post-failure. Firstly three fault-tolerant indexes, reduced condition number, sudden change of relative joint velocity and centrality are proposed, which can comprehensively evaluate the kinematical performance of a redundant robot during its entire fault-tolerant operations. Then, the influence of the initial postures of robot＇s end-effector on these fault-tolerant indexes is analyzed with a planar robot and a spatial robot. Simulation results show that for a given task the joint trajectory with the best comprehensive effect of fault tolerance can be determined by optimizing the initial posture of a robot.

关键词： Redundant robot Fault-tolerant properties Comprehensive evaluation

Linking satellite-based spring phenology to temperate deciduous broadleaf forest photosynthesis activity

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International Journal of Digital Earth 2014年第11期7卷 881-896页

作者： jing-jing zhao Liang-Yun Liu Key Laboratory of Digital Earth Science Center for Earth Observation and Digital EarthUniversity of Chinese Academy of SciencesBeijingChina

Satellite-based remote sensed phenology has been widely used to assess global climate ***,it is constrained by uncertain linkages with photo-synthesis *** dynamic threshold methods were employed to retrieve spring phenology metrics from four Moderate Resolution Imaging Spectro-radiometer(MODIS)products,including fraction of Absorbed Photosyntheti-cally Active Radiation(fAPAR),Leaf Area Index(LAI),Normalized Difference Vegetation Index(NDVI),and Enhanced Vegetation Index(EVI)for three temperate deciduous broadleaf forests in North America between 2001 and *** MODIS-based spring phenology metrics were subsequently linked to the photosynthetic curves(daily gross primary productivity,GPP)measured by an eddy covariance flux *** 20% dynamic threshold spring onset metrics from MODIS products were closer to the photosynthesis onset metrics at the date of 2% GPP increase for NDVI and fAPAR,and closer to the date of 5%and 10% increase of GPP for EVI and LAI,*** 50% dynamic threshold onset metrics were closer to the photosynthesis onset metrics at the date of 10%GPP increase for NDVI,and closer to the date of 20% GPP increase for fAPAR,LAI and EVI,*** results can improve our knowledge on the photosynthesis activity status of remotely sensed spring phenology metrics.

关键词： MODIS spring phenology deciduous broadleaf forest GPP eddy covariance flux tower photosynthesis activity period

The Strategic Analysis of Demand Forecast-Sharing in a Hybrid-Format Online Platform Supply Chain

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Journal of Systems Science and Systems Engineering 2024年第3期33卷 281-310页

作者： jing zhao Zijun Yin Guobiao Zhou School of Mathematical Sciences Tiangong UniversityTianjin300387China

This paper examines the optimal forecast-sharing strategy in a hybrid-format online platform supply chain where a supplier sells a product through agency format and reselling format provided by a platform retailer who possesses demand forecasts from two *** asymmetry and co-opetitive relationship arise between the platform retailer and the supplier,which affect their operational decisions and the supply chain’s *** improve supply chain efficiency,we compare different forecast-sharing strategies(i.e.,no forecast sharing,sharing a single forecast,and sharing two forecasts),and analyze the effects of co-opetitive parameters on the optimal forecast-sharing *** analysis shows that forecast sharing is always beneficial to the supplier,and sharing two forecasts is more beneficial than sharing a single *** for the platform retailer and the whole supply chain,forecast sharing is beneficial only under certain conditions,depending on the co-opetitive *** optimal forecast-sharing strategy is the result of a combination of the negative effect of double marginalization in reselling channel and the positive effect of responding pricing to demand uncertainty in agency *** illustrate the parameter regions of the platform retailer’s voluntary sharing,contract sharing,and no sharing,and also find that higher channel competition intensity,higher market share of agency channel,and higher commission rate can promote the platform retailer’s voluntary *** study extends the research scope of demand forecast-sharing and sheds light on the decision-making processes for managing a hybrid-format online platform supply chain.

关键词： Supply chain management hybrid-format online platform demand forecast-sharing co-opetitive relationship channel competition intensity

The ANOVA-Type Inference in Linear Mixed Model with Skew-Normal Error

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Journal of Systems Science & Complexity 2017年第3期30卷 710-720页

作者： WU Mixia zhao jing WANG Tonghui zhao Yan College of Applied Sciences Beijing University of Technology Department of Mathematical Sciences New Mexico State University

Linear mixed effect models with skew-normal errors and distribution-free random effects are considered. The ANOVA-type F-tests are proposed to test the significance of random effects and the hypothesis on fixed effects of interest, respectively. Both tests are proved to be exact F-tests under this model, and the exact confidence interval for fixed effects of interest is derived. Simulation results are given to study the powers of ANOVA-type tests.

关键词： ANOVA-type estimator ANOVA-type F-test skew-normal error.