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Advances in ethnopharmacology,phytochemistry and pharmacology of Erigerontis Herba and its Chinese medicine prescriptions

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Traditional Medicine Research 2025年第1期10卷 44-61页

作者： Yang Zhou Yuan-Yan Huang Ding-Yue Shang Ying Chen Meng Tian Cheng-Yu jin Xin Lu Bing-Chun Yan Han-Qing Pang Institute of Translational Medicine School of MedicineYangzhou UniversityYangzhou 225009China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases Yangzhou UniversityYangzhou 225009China School of Medicine Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Guangxi Normal UniversityGuiling 541004China.

Erigerontis Herba(EH),the dried whole plant of Erigeron breviscapus,is well-known for circulating blood,activating meridians to alleviate pain,expelling wind,and clearing away *** has been extensively utilized in southern China for the treatment of stroke hemiplegia,chest stuffiness and pains,rheumatic arthralgia,headache,and *** review focuses on the botany,ethnopharmacology,phytochemistry,pharmacology and toxicity of EH and its related prescriptions to offer new insights for prospective research of *** information about EH was retrieved from ancient records and books,PubMed,China National Knowledge Infrastructure,Chinese Pharmacopoeia,Web of Science,Doctoral and Master’s Theses,and various electronic *** is a member of Compositae family and is mainly grown in southern *** Chinese medicine records that EH has the effects of circulating blood and removing blood stasis,expelling wind,and removing cold,as well as relieving rigidity of muscle and relieving *** now,nearly 200 ingredients have been characterized from EH,including flavonoids,caffeoyls,aromatic acids,coumarins,pentacyclic terpenoids,volatile oil and other *** extracts,EH related prescriptions(Dengzhan Xixin injection,Dengzhan Shengmai capsules,etc.)or compounds(scutellarin,scutellarein,etc.)possessed obvious therapeutic effects of ischemic stroke,cerebral hemorrhage,myocardial infarction,Alzheimer’s disease,diabetes and its complications,gastric cancer,bone,and joint degenerative ***,the major active compound of EH,has been used as a quality *** no obvious toxicity of EH has been *** to its traditional applications,ethnopharmacology,phytochemistry,pharmacology,and toxicity,EH was applied as a valuable herb for clinical application in food and medicine *** several compounds have been shown to possess diverse biological activities,the underlying mechanisms of their actions remain *** fully exploi

关键词： Erigeron breviscapus traditional applications ethnopharmacology phytochemistry pharmacology

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基于语料库的朝鲜语命名实体结构特征研究

外语学刊 2025年第1期 9-18页

作者：黄政豪金光洙延边大学工学院延吉133002 延边大学外国语学院延吉133002

本文统计Klue⁃ner和Kochet⁃ner两个命名实体语料库中的新闻、评论和文化遗产文本数据包含的不同类别朝鲜语命名实体。根据统计结果分析朝鲜语命名实体的音节长度特征分布和格词尾结合率。分析结果表明,音节长度和格词尾的使用在命名实... 详细信息

本文统计Klue⁃ner和Kochet⁃ner两个命名实体语料库中的新闻、评论和文化遗产文本数据包含的不同类别朝鲜语命名实体。根据统计结果分析朝鲜语命名实体的音节长度特征分布和格词尾结合率。分析结果表明,音节长度和格词尾的使用在命名实体分类中具有一定的规律可循。本文的研究成果可用于命名实体分类工作,同时也可以为朝鲜语命名实体语料库构建提供分布结构建议。

关键词：朝鲜语格词尾命名实体识别特征提取名词分类

山姜素调节cAMP/PKA/CREB信号通路促进骨质疏松性骨折大鼠骨折愈合

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中国组织工程研究 2025年第12期29卷 2438-2443页

作者：陆飞周静金涛连云港市第一人民医院康复医学科江苏省连云港市222000 南京医科大学康达学院康复医学部江苏省连云港市222000 中国人民解放军东部战区总医院健康医学科江苏省南京市210018

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作... 详细信息

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作用。方法:采用双侧卵巢切除手术构建骨质疏松症骨折大鼠模型,将成功造模大鼠依据随机数字表法分为山姜素低、中、高剂量组、抑制剂组和模型组,另选12只大鼠作为假手术组。骨折造模当天,山姜素低、中、高剂量组大鼠灌胃7.5,15,30 mg/kg的山姜素+腹腔注射等量的生理盐水,抑制剂组灌胃30 mg/kg的山姜素+腹腔注射5 mg/kg的H-89(通路抑制剂),模型组与假手术组给予(灌胃+腹腔注射)等量生理盐水,1次/d,连续8周。放射性检查评估大鼠骨折愈合情况并进行愈合评分;骨密度扫描仪测定骨折处骨密度;通过三点弯曲实验和压缩实验评估大鼠股骨生物力学状况;苏木精-伊红染色观察大鼠骨折处病理损伤;酶联免疫吸附(ELISA)法检测血清碱性磷酸酶、骨钙素和Ⅰ型胶原交联C-末端肽、环磷酸腺苷水平的变化;Western blot检测股骨组织中骨形态发生蛋白2和环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白通路蛋白表达。结果与结论:①相较于假手术组,模型组大鼠骨折愈合评分、骨密度、最大负荷、最大应力、碱性磷酸酶、骨钙素、环磷酸腺苷水平、骨形态发生蛋白2、磷酸化蛋白激酶A/蛋白激酶A、磷酸化环磷酸腺苷反应元件结合蛋白/环磷酸腺苷反应元件结合蛋白表达下降,Ⅰ型胶原交联羧基末端肽水平增加(P<0.05);与模型组比较,山姜素各剂量组大鼠上述各项指标呈现相反的变化(P<0.05);与山姜素高剂量组比较,抑制剂组大鼠上述指标变化均被逆转(P<0.05)。②结论:山姜素可能通过激活环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路加速骨质疏松症骨折大鼠的骨折愈合。

关键词：山姜素环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白骨质疏松骨折愈合大鼠

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面向轴承生产线的视觉检测光源系统

轴承 2025年第1期 88-94页

作者：黄振宇金京钱淼浙江理工大学机械工程学院杭州310018 浙江迎丰科技股份有限公司浙江绍兴312073

为降低工业自动化生产过程中轴承端面块状瑕疵的漏检率和误检率,对视觉检测常用的光源类型进行了对比试验,在工业环境下采用不同光源获取图像并使用不同的图像增强算法进行优化处理,通过像素点检测的方式检测轴承端面块状瑕疵,以工厂的... 详细信息

为降低工业自动化生产过程中轴承端面块状瑕疵的漏检率和误检率,对视觉检测常用的光源类型进行了对比试验,在工业环境下采用不同光源获取图像并使用不同的图像增强算法进行优化处理,通过像素点检测的方式检测轴承端面块状瑕疵,以工厂的检测标准进行应用验证。结果表明:同轴光源作为视觉光源时所采集图像在各种图像增强算法处理下的检测效果均好于其他光源;自适应直方图均衡化对轴承端面瑕疵的总体检测效果较好,Gamma变换则对降低漏检率有较好作用。

关键词：滚动轴承机器视觉光源表面缺陷检测图像处理

Comparative study of static and dynamic parameters of rock for the Xishan Rock Cliff Statue

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第10期12卷 771-781页

作者： jin JIANG jin-zhong SUN School of Civil and Environmental Engineering Nanyang Technological University 639798 Singapore School of Engineering and Technology China University of Geosciences Beijing 100083 China

Ultrasonic wave testing was applied to investigate the quality and weathering status of rock specimens obtained in two borings situated in the Xishan Buddha rock slope in Taiyuan, China. This paper pays special attention to the distribution of bulk density, dynamic parameters and static parameters of rock specimens as well as the relationship between static and dynamic parameters. The results illustrate that the distribution of both parameters is identical along the depth of two drilled holes in the rock slope. When the hole depth increases, the density of rock mass, saturated compression strength and static elastic modulus, dynamic elastic modulus and wave velocity also show increase tendency. The weathering degree in the rock mass ranging from the surface of cliff to the depth of 2.5 m is the highest while the rock mass is unsalted and more rigid when the depth is larger than 3.0 m. The relationship between dynamic elastic modulus, sonic wave velocity and horizontal depth indicates that dynamic elastic modulus is more sensitive than sonic wave velocity. Conversely, by comparing quantity relationship between static elastic modulus and sonic wave velocity, it is found that the composition of rock has a great influence on the relationship between static and dynamic parameters, that is, inequality of rock composition will lead to dispersion and abnormality of the distribution of static and dynamic parameters.

关键词： Xishan Buddha Rock mechanics Rock quality Elastic wave velocity Elastic modulus Compression strength Ultrasonic wave testing

Recent progress on photoactive nonprecious transition-metal complexes

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Science China Chemistry 2025年第1期 46-95页

作者： Zhong-Liang Gong Hong-Jie Zhang Yan Cheng Jianxun Liu Yuhan Ai Yaqin Li Zhihui Feng Qiong Zhang Shaolong Gong Yong Chen Chang-Jiang Yao Yuan-Yuan Zhu Liang-jin Xu Yu-Wu Zhong CAS Key Laboratory of Photochemistry Institute of Chemistry Chinese Academy of Sciences State Key Laboratory of Structural Cemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences School of Chemistry and Chemical Engineering Anhui Key Laboratory of Advanced Catalytic Materials and Reaction EngineeringHefei University of Technology State Key Laboratory of Explosion Science and Safety Protection School of Mechatronical Engineering Beijing Institute of Technology College of Chemistry and Molecular Sciences Hubei Key Lab on Organic and Polymeric Optoelectronic Materials Wuhan University School of Chemistry and Chemical Engineering Anhui University Key Laboratory of Photochemical Conversion and Optoelectronic Materials & CAS-HKU Joint Laboratory on New Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences

Photoactive complexes of nonprecious transition metals, mainly including those in the first-row and partially the second-row of the Periodic table of elements, have received increasing attention in view of their low cost and long-term sustainability. They are recognized as promising alternatives to noble transition metal complex congeners that have been extensively studied in optoelectronic devices, artificial photosynthesis, photocatalysis, biodiagnostics, and therapeutics, etc. This review is devoted to a comprehensive summary on the classical and recent advances on photoactive nonprecious transition metal complexes, including photoactive Zr, V, Cr, Mo, and W complexes, Mn complexes and hybrids, Fe, Co, Ni, and Cu complexes, and Zn and Cd complexes and hybrids. A particular focus is given on the molecular design, modulation of photophysical and photochemical properties, and applications of the representative and lately-developed nonprecious metal complexes. In addition, a perspective on the future development in this field is provided at the end of this review.

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Effect of Tip Flange on Tip Leakage Flow of Small Axial Flow Fans

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Journal of Thermal Science 2014年第1期23卷 45-52页

作者： ZHANG Li jin Yingzi jin Yuzhen The Province Sky Lab of Fluid Transmission Technology Zhejiang Sci-Tech University

Aerodynamic performance of an axial flow fan is closely related to its tip clearance leakage flow. In this paper, the hot-wire anemometer is used to measure the three dimensional mean velocity near the blade tips. Moreover, the filtered N-S equations with finite volume method and RNG k-s turbulence model are adopted to carry out the steady simulation calculation of several fans that differ only in tip flange shape and number. The large eddy simulation and the FW-H noise models are adopted to carry out the unsteady numerical calculation and aerodynamic noise prediction. The results of simulation calculation agree roughly with that of tests, which proves the numerical calculation method is *** effects of tip flange shapes and numbers on the blade tip vortex structure and the characteristics are analyzed. The results show that tip flange of the fan has a certain influence on the characteristics of the fan. The maximum efficiencies for the fans with tip flanges are shifted towards partial flow with respect to the design point of the dattun fan. Furthermore, the noise characteristics for the fans with tip flanges have become more deteriorated than that for the datum fan. Tip flange contributes to forming tip vortex shedding and the effect of the half-cylinder tip flange on tip vortex shedding is obvious. There is a distinct rela- tionship between the characteristics of the fan and tip vortex *** research results provide the profitable reference for the internal flow mechanism of the performance optimization of small axial flow fans.

关键词： Tip Flange Tip Leakage Flow Small Axial Flow Fan Performance

On-orbit real-time magnetometer bias determination for micro-satellites without attitude information

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Chinese Journal of Aeronautics 2015年第5期28卷 1503-1509页

作者： Zhang Zhen Xiong Jianping jin jin Department of Precision Instrument Tsinghua University Space Center Tsinghua University

Due to the disadvantages such as complex calculation, low accuracy of estimation, and being non real time in present methods, a new real-time algorithm is developed for on-orbit mag- netometer bias determination of micro-satellites without attitude knowledge in this paper. This method uses the differential value approach. It avoids the impact of quartic nature and uses the iterative method to satisfy real-time applications. Simulation results indicate that the new real-time algorithm is more accurate compared with other methods, which are also tested by an experiment system using real noise data. With the new real-time algorithm, a magnetometer calibration can be taken on-orbit and will reduce the demand for computing power effectively.

关键词： Magnetometer bias:On-orbit determinationMicro-satellite Attitude-independent Real-time

基于包络互相关定位方法的积石山M_(S)6.2地震前超低频地震研究

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大地测量与地球动力学 2025年第1期45卷 66-71页

作者：张晓阳邓津李淑婷中国地震局兰州地震研究所兰州市730000 兰州地球物理国家野外科学观测研究站兰州市730000

利用包络互相关方法对积石山M_(S)6.2地震前的超低频地震进行定位。先在较大范围内进行初步定位,然后在较小范围内进行精确定位。通过增加或减少震源不同方位的台站数量进行分析,结果显示,台站在各个方位上的均匀分布至关重要,可以有效... 详细信息

利用包络互相关方法对积石山M_(S)6.2地震前的超低频地震进行定位。先在较大范围内进行初步定位,然后在较小范围内进行精确定位。通过增加或减少震源不同方位的台站数量进行分析,结果显示,台站在各个方位上的均匀分布至关重要,可以有效减小定位误差。定位结果表明,积石山地震前的超低频地震主要分布在断裂带附近,分布方位和断层方向保持一致。

关键词：积石山地震超低频地震地震定位包络互相关

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