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Multiple ectopic goiter in the retroperitoneum,abdominal wall,liver,and diaphragm:A case report and review of literature

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World Journal of Clinical Cases 2020年第23期8卷 6172-6180页

作者： Lan-Hui Qin Feng-Yi He jin-yuan liao Department of Radiology Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Radiology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Ectopic thyroid is a rare developmental disorder,typically found in lingual areas,and most distantly in the *** ectopia in multiple regions is extremely *** date,there are no reports of ectopic goiter in four regions of the abdominal cavity in a single *** SUMMARY We present a case of thyroid ectopia in four areas of the abdomen,comprising normal orthotopic thyroid tissue.A 36-year-old woman,who underwent ovarian teratoma resection 10 years previously due to symptomatic ovarian teratoma,was referred to our hospital for treatment of an incidental hepatic *** resonance imaging and computed tomography(CT)of the abdomen showed a heterogeneously enhanced lobulated lesion in the sixth and seventh hepatic segment adjacent to the *** mass was surgically excised,and histologic examination determined an ectopic nodular *** the one-year follow-up,the abdominal CT scan,whole-body radionuclide I131 examination,and abdominal wall biopsy showed similar lesions in the left renal fascia and anterior abdominal *** Multiple para-ectopic thyroid is often misdiagnosed,owing to its extremely rare incidence and non-specific clinical manifestations and imaging features.A combination of multiple examinations is necessary for diagnostic accuracy.

关键词： Ectopic thyroid Magnetic resonance imaging Computed tomography 99mTc sodium pertechnetate scintigraphy Case report

Analysis of Bright Source Hardness Ratios in the 4 yr Insight-HXMT Galactic Plane Scanning Survey Catalog

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Research in Astronomy and Astrophysics 2024年第2期24卷 154-170页

作者： Chen Wang jin-yuan liao Ju Guan yuan Liu Cheng-Kui Li Na Sai jing jin Shuang-Nan Zhang Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Astronomy School of Physics and TechnologyWuhan UniversityWuhan 430072China WHU-NAOC Joint Center for Astronomy Wuhan UniversityWuhan 430072China

We conduct a statistical analysis of the hardness ratio(HR)for bright sources in the 4 yr Galactic Plane Scanning Survey catalog of *** on the stable(variable)flux F_(s)(F_(v))or spectrum S_(s)(S_(v))of each source,the bright sources are classified into three groups:F_(v)&S_(v),F_(v)&S_(s),and F_(s)&_(s).Our study of the HR characteristics in different types of sources reveals that accretion-powered neutron star(NS)low-mass X-ray binaries(LMXBs)exhibit softer energy spectra than NS high-mass X-ray binaries(HMXBs),but harder energy spectra than black hole binaries in most *** difference is probably due to their different magnetic field ***,Fv&Sv LMXBs tend to be harder than Fv&Ss LMXBs below 7 keV,while the opposite is true for *** results suggest that LMXBs may dominate unclassified sources,and NS binaries are likely to be the primary type of X-ray binaries with ambiguous compact *** comparing the HR of transient sources in their outburst and low-flux states,it is found that the averaged HR of four sources in the two states are roughly comparable within *** also investigate the spatial properties of the three groups and find that Fv&Sv sources are mainly located in the longitude of-20°

关键词： catalogs-surveys-methods data analysis-X-rays general

Three-dimensional computed tomography reconstruction diagnosed digestive tract perforation and acute peritonitis caused by Monopterus albus:A case report

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World Journal of Gastrointestinal Surgery 2023年第10期15卷 2351-2356页

作者： jin-Han Yang jin-Ying Lan An-yuan Lin Wei-Biao Huang jin-yuan liao Department of Radiology Guiping People’s HospitalGuigang 537200Guangxi Zhuang Autonomous RegionChina Department of Radiology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Few reports have described living foreign bodies in the human *** current manuscript demonstrates that computed tomography(CT)is an effective tool for accurate preoperative evaluation of living foreign bodies in *** threedimensional(3D)reconstruction technology could clearly display anatomical structures,lesions and adjacent organs,improving diagnostic accuracy and guiding the surgical decision-making *** SUMMARY Herein we describe a 68-year-old man diagnosed with digestive tract perforation and acute peritonitis caused by a foreign body of Monopterus *** patient pre-sented to the emergency department with complaints of dull abdominal pain,profuse sweating and a pale complexion during work.A Monopterus albus had entered the patient’s body through the anus two hours *** hospitalization,the 3D reconstruction technology revealed a perforation of the middle rectum complicated with acute peritonitis and showed a clear and complete Monopterus albus bone morphology in the abdominal and pelvic cavities,with the Monopterus albus biting the *** examination detected a large(diameter of about 1.5 cm)perforation in the *** could be seen that a Monopterus albus had completely entered the abdominal cavity and had tightly bitten the mesentery of the small *** the operation,the dead Monopterus albus was taken *** The current manuscript demonstrates that CT is an effective tool for accurate preoperative evaluation of living foreign bodies in clinic.

关键词： Digestive tract perforation Acute peritonitis Monopterus albus Three-dimensional computed tomography reconstruction Case report

Localization Method for the Pointing Observation with the Collimated Telescopes of Insight-HXMT

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Research in Astronomy and Astrophysics 2023年第5期23卷 38-43页

作者： Qi Luo jin-yuan liao Yi Nang Cheng-Kui Li Chen Wang Na Sai Ju Guan Yu-Peng Chen Cheng-Cheng Guo yuan Liu Shu Zhang Shuang-Nan Zhang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Physics and Technology Wuhan UniversityWuhan 430072China WHU-NAOC Joint Center for Astronomy Wuhan UniversityWuhan 430072China

An accurate target source position is sometimes useful for the pointing observation with the collimated telescopes of the Hard X-ray Modulation Telescope(Insight-HXMT),which is determined by the reliability of the instrumental ***-HXMT has the unique design that all three main payloads(LE,ME and HE)consist of detector groups with three fields of views(FOVs)whose orientations differ by 60°.As the point-spread functions are different at different positions in the FOV coordinates,the count rate ratios between the detector groups depend on the position of an X-ray source in the *** on the multi-FOV design,we develop a localization method for an X-ray source in the pointing observation of *** accuracy of the method is investigated with the pointing observations of the Crab with different *** find that the statistical error decreases with the exposure,and the systematic error is dominant for the exposure>128 *** the exposure of1024 s,the total error is 0°.015 for the *** method can effectively distinguish the Rapid Burster H 1730–333and Slow Burster GX 354–0,which are only 0°.5 apart and can both contribute to bursts in the light curve obtained by *** also apply the pointing observation localization method to locate the X-ray counterpart of FRB 200428 with high *** located position is consistent with SGR J1935+2154 within 1σuncertainty of 10′,which provides important evidence that fast radio bursts can originate from magnetars.

关键词： instrumentation detectors-space vehicles instruments-telescopes

Five-year in-orbit background of Insight-HXMT

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Radiation Detection Technology and Methods 2023年第1期7卷 34-47页

作者： jin-yuan liao Shu Zhang Juan Zhang Gang Li Zhi Chang Yu-Peng Chen Ming-Yu Ge jing jin Xue-Feng Lu yuan You Xue-Lei Cao Yong Chen Yue Huang Wei-Chun Jiang Xiao-Bo Li Xu-Fang Li Zheng-Wei Li Cong-Zhan Liu Ying Tan Yan-Ji Yang Yi-Fei Zhang Hai-Sheng Zhao Fang-Jun Lu Yu-Peng Xu jin-Lu Qu Li-Ming Song Shuang-Nan Zhang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences19B Yuquan RoadShijingshan DistrictBeijing 100049China Key Laboratory of Stellar and Interstellar Physics and School of Physics and Optoelectronics Xiangtan UniversityYuhu DistrictXiangtan 411105China University of Chinese Academy of Sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of Sciences20A Datun RoadChaoyang DistrictBeijing 100012China

Purpose We present the five-year in-orbit background evolution of Insight-HXMT since the launch,as well as the effects of the background model in data *** The backgrounds of the three main payloads,i.e.,low-energy telescope,medium-energy telescope,and high-energy telescope,are *** evolution of the background over time is obtained by simply comparing the background in every year during the in-orbit operation of *** The major observational characteristics of the Insight-HXMT in-orbit background are presented,including the light curve,spectrum,geographical distribution,and long-term *** systematic error in background estimation is investigated for every *** The observational characteristics of the five-year in-orbit background are consistent with our knowledge of the satellite design and the space environment,and the background model is still valid for the latest observations of Insight-HXMT.

关键词： Instrumentation:detectors Space vehicles:instruments Methods:data analysis X-rays:general

FK506 contributes to peripheral nerve regeneration by inhibiting neuroinflammatory responses and promoting neuron survival

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Neural Regeneration Research 2025年第7期20卷 2108-2115页

作者： Yuhui Kou Zongxue jin Yusong yuan Bo Ma Wenyong Xie Na Han Department of Trauma and Orthopedics Peking University People’s HospitalBeijingChina National Center for Trauma Medicine Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration(Peking University) Ministry of EducationBeijingChina Trauma Medicine Center Peking University People’s HospitalBeijingChina Department of Orthopedics China-Japan Friendship HospitalBeijingChina

FK506(Tacrolimus)is a systemic immunosuppressant approved by the *** and Drug ***506 has been shown to promote peripheral nerve regeneration,however,its precise mechanism of action and its pathways remain *** this study,we established a rat model of sciatic nerve injury and found that FK506 improved the morphology of the injured sciatic nerve,increased the numbers of motor and sensory neurons,reduced inflammatory responses,markedly improved the conduction function of the injured nerve,and promoted motor function *** findings suggest that FK506 promotes peripheral nerve structure recovery and functional regeneration by reducing the intensity of inflammation after neuronal injury and increasing the number of surviving neurons.

关键词： FK506 inflammation motor neurons nerve regeneration neuron peripheral nerve injury sensory neurons

计算机科学教育:人人享有的机会——美国《K-12计算机科学框架》的特点与启示

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电化教育研究 2017年第3期38卷 12-17页

作者：卢蓓蓉尹佳高守林金凯廖媛任友群华东师范大学教育学部教育信息技术学系上海200062 华东师范大学教育学部课程与教学研究所上海200062

《K-12计算机科学框架》提出了新时期美国K-12计算机科学教育的发展愿景及实现路径,明确了计算系统、网络和互联网、数据和分析、算法和编程、计算的影响等五大核心概念,提出了创建全纳的计算文化、通过计算开展合作、识别和定义计算问... 详细信息

《K-12计算机科学框架》提出了新时期美国K-12计算机科学教育的发展愿景及实现路径,明确了计算系统、网络和互联网、数据和分析、算法和编程、计算的影响等五大核心概念,提出了创建全纳的计算文化、通过计算开展合作、识别和定义计算问题、发展和使用抽象思考、创造计算产品、测试和改善计算产品、计算的沟通等七大核心实践,提出了计算机科学和学前教育重要理念的整合途径。推进我国计算机科学教育,应提高中小学计算机科学课程地位,在学前教育中恰当引入计算机科学教育,注重中小学计算机科学课程的系统性与实践性,强调重视计算机科学教育研究及其成果运用。

关键词：计算机科学教育 K-12 美国计算思维学前教育

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑yuan Yu jing Wu Guang Yin Fan‑Zhen Jiao Zhong‑Zhen Yu jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin jin Yiming Qin Feifei yuan Hongbin Lu Jianzhong Hu Yong Cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2