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Deformation behavior and plastic instability of boronized Al0.25CoCrFeNi high-entropy alloys

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International Journal of Minerals,Metallurgy and Materials 2020年第10期27卷 1363-1370页

作者： jin-xiong hou jing Fan Hui-jun Yang Zhong Wang Jun-wei Qiao College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials(Ministry of Education Taiyuan University of TechnologyTaiyuan 030024China

Using thermochemical treatments,boronized layers were successfully prepared on Al0.25CoCrFeNi high-entropy alloys(HEAs).The thickness of the boronized layers ranged widely from 20 to 50μm,depending on the heat treatment *** remarkably improved the surface hardness from HV 188 to HV 1265 after treating at 900°C for 9 ***,boronizing enhanced the yield strength of HEAs from 195 to 265 MPa but deteriorated the tensile *** crackings in the boride layers significantly decreased the *** insufficient work-hardening capacity essentially facilitated the plastic instability of the boronized *** decreasing substrate thickness,the fracture modes gradually transformed from dimples to quasi-cleavage and eventually to cleavage.

关键词： boronizing high-entropy alloys boride layers tensile strength cleavage fracture

Tensile strength prediction of dual-phase Al0.6CoCrFeNi high-entropy alloys

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International Journal of Minerals,Metallurgy and Materials 2020年第10期27卷 1341-1346页

作者： Min Zhang jin-xiong hou Hui-jun Yang Ya-qin Tan Xue-jiao Wang Xiao-hui Shi Rui-peng Guo Jun-wei Qiao College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China

The evolution of the microstructure and tensile properties of dual-phase Al0.6CoCrFeNi high-entropy alloys(HEAs)subjected to cold rolling was *** homogenized Al0.6CoCrFeNi alloys consisted of face-centered-cubic and body-centered-cubic phases,presenting similar mechanical behavior as the as-cast *** yield and tensile strengths of the alloys could be dramatically enhanced to^1205 MPa and^1318 MPa after 50%rolling reduction,respectively.A power-law relationship was discovered between the strain-hardening exponent and rolling *** tensile strengths of this dual-phase HEA with different cold rolling treatments were predicted,mainly based on the Hollomon relationship,by the strain-hardening exponent,and showed good agreement with the experimental results.

关键词： dual-phase high-entropy alloys cold rolling strain-hardening exponent tensile strength

Machine learning-based models for advanced fibrosis in nonalcoholic steatohepatitis patients:A cohort study

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World Journal of Gastroenterology 2025年第9期31卷 30-42页

作者： Fei-Xiang xiong Lei Sun Xue-Jie Zhang Jia-Liang Chen Yang Zhou Xiao-Min Ji Pei-Pei Meng Tong Wu Xian-Bo Wang Yi-Xin hou Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Department of Pathology Beijing Ditan HospitalBeijing 100015China

BACKGROUND The global prevalence of non-alcoholic steatohepatitis(NASH)and its associated risk of adverse outcomes,particularly in patients with advanced liver fibrosis,underscores the importance of early and accurate *** To develop a machine learning-based diagnostic model for advanced liver fibrosis in NASH *** A total of 749 patients who underwent liver biopsy at Beijing Ditan Hospital,Capital Medical University,between January 2010 and January 2020 were *** were randomly divided into training(n=522)and validation(n=224)*** machine learning models were applied to predict advanced liver fibrosis,with feature selection based on Shapley Additive Explanations(SHAP).The diagnostic performance of these models was compared to traditional scores such as the aspartate aminotransferase to platelet ratio index(APRI)and fibrosis index based on the 4 factors(FIB-4),using metrics including the area under the receiver operating characteristic curve(AUROC),decision curve analysis(DCA),and calibration *** The Extreme Gradient Boosting(XGBoost)model outperformed all other machine learning models,achieving an AUROC of 0.934(95%CI:0.914-0.955)in the training cohort and 0.917(95%CI:0.880-0.953)in the validation cohort(P<0.001).Incorporating liver stiffness measurement into the model further improved its performance,with an AUROC of 0.977(95%CI:0.966-0.980)in the training cohort and 0.970(95%CI:0.950-0.990)in the validation cohort,significantly surpassing APRI and FIB-4 scores(P<0.001).The XGBoost model also demonstrated superior clinical utility,as evidenced by DCA and calibration curve analysis in both *** The XGBoost model provides a highly accurate,non-invasive diagnosis of advanced liver fibrosis in NASH patients,outperforming traditional *** online tool based on this model has been developed to assist clinicians in evaluating the risk of advanced liver fibrosis.

关键词： Machine learning Advanced fibrosis Non-alcoholic steatohepatitis Extreme Gradient Boosting Non-invasive

Novel anti-inflammatory peptide alleviates liver ischemia-reperfusion injury

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Journal of Biomedical Research 2025年第1期39卷 61-75页

作者： Xuejun Xu Kaineng Sun Hao Chang Chunxiang Shen Xiangdong Li Yangyue Ni Yuxiao Zhu Huiquan Wang Ruiyan xiong Jon Rob Padde Zhipeng Xu Lin Chen Lu Chen Min hou Liyong Pu Minjun Ji Department of Pathogen Biology National Vaccine Innovation PlatformJiangsu Province Engineering Research Center of Antibody DrugSchool of Basic Medical SciencesNanjing Medical UniversityNanjingJiangsu 211166China Hepatobiliary Center Jiangsu Province Hospital and Nanjing Medical University First Affiliated HospitalNanjingJiangsu 210029China

Ischemia-reperfusion injury(IRI)remains an unavoidable challenge in liver surgery,with macrophages playing a critical role in its ***,the mechanisms by which macrophages regulate the pathogenesis of IRI are not well *** a target-guided screening approach,we identified a small 3 k Da peptide(Sj DX5-271)from various schistosome egg-derived peptides that induced M2 macrophage ***5-271 treatment protected mice against liver IRI by promoting M2 macrophage polarization,and this protective effect was abrogated when the macrophages were *** sequencing showed that the TLR signaling pathway was significantly inhibited in macrophages from the SjDX5-271 treatment *** further identified that SjDX5-271 promoted M2 macrophage polarization by inhibiting the TLR4/My D88/NF-κB signaling pathway and alleviated hepatic inflammation in liver ***,SjDX5-271 exhibited some promising therapeutic effects in IRI and represented a novel therapeutic approach,potentially applicable to other immune-related *** current study demonstrates the potential of new biologics from the parasite,enhances our understanding of host-parasite interplay,and provides a blueprint for future therapies for immunerelated diseases.

关键词： schistosome-derived peptide liver ischemia-reperfusion injury macrophage toll-like receptor-4

Numerical analysis and optimization of the inlet stage of a multi-stage high pressure compressor

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航空动力学报 2007年第8期22卷 1356-1364页

作者： XU Quan-yong hou An-ping xiong jin-song Zhou Sheng National Key Laboratory on Aero-engines School of Jet Propulsion Beijing University of Aeronautics and Astronautics Beijing 100083

An opti mization process is used to redesign blades of a high-pressure *** artificial neural network (ANN) method is coupled to Navier-Stokes solvers and is applied to three different redesigns.A newrotor blade of a transonic compressor is designed by modifying thick,stacking line andinlet angle using a 3Dapproach,with a significant efficiencyi mprovement at the design *** off-design behavior of this new compressor is also checked afterwards,which shows that the whole performance of the inlet stage is improved over a wide range of mass *** losses are reduced,proving the good performance of the opti *** whole results indicate that the opti mization method can find i mproved design and can be integrated in a design procedure.

关键词：数学分析最优化航天推进系统高压压缩机人工神经网络叶栅

自媒体时代教育舆情的特征、演化机制及引导路径

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教学与管理 2025年第6期 27-31页

作者：马善恒叶露阳王后雄华中师范大学教师教育学院武汉430079 华东师范大学附属东昌中学上海200120 平顶山学院化学与环境工程学院河南平顶山467000

随着强化全媒体传播体系建设,打造主导舆情新局面,完善互联网综合治理系统,推进构建良性互联网环境的推进,教育舆情已经快速发展到一个新的高度,它不仅反映出人们的情感、态度、行动,更体现出人们对教学的关注和期望,这种舆情的影响力... 详细信息

随着强化全媒体传播体系建设,打造主导舆情新局面,完善互联网综合治理系统,推进构建良性互联网环境的推进,教育舆情已经快速发展到一个新的高度,它不仅反映出人们的情感、态度、行动,更体现出人们对教学的关注和期望,这种舆情的影响力正在不断增强。深入探讨教育舆情的主体、客体以及空间等多个维度,以期更好地适应人们的教育需要,推进素质教育建设。深入研究教育舆情的本质及其影响力,可以更好地理解自媒体时代教育舆情的发展趋势,从而探索教育舆情治理的新方法和新思路,努力营造良好教育发展舆论生态,构建完善的教育舆情管理体系,发挥教育舆情的积极价值,助力教育事业高质量发展。

关键词：自媒体时代教育舆情舆情引导

Airborne Investigation of Riming:Cloud and Precipitation Microphysics within a Weak Convective System in North China

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Advances in Atmospheric Sciences 2025年第3期42卷 515-526页

作者： Xiangfeng HU Hao HUANG Shaoyu hou Kun ZHAO Chuanfeng ZHAO Yinghui LU Jiefang YANG Rong ZHANG Delong ZHAO Weiguo LIU Dan ZHANG Haixia XIAO Key Laboratory of Radar Meteorology and State Key Laboratory of Severe Weather China Meteorology AdministrationBeijing 100044China China Meteorological Administration xiong'an Atmospheric Boundary Layer Key Laboratory Xiong'an New AreaHebei 071703China Hebei Provincial Weather Modification Center ShijiazhuangHebei 051430China School of Atmospheric Sciences Key Laboratory of Mesoscale Severe Weather/MOEand Frontiers Science Center for Critical Earth Material CyclingNanjing UniversityJiangsu 210023China Department of Atmospheric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Cloud-Precipitation Physics and Weather Modification Key Laboratory China Meteorology AdministrationBeijing 100044China Beijing Weather Modification Center Beijing 100089China Nanjing Joint Institute for Atmospheric Sciences NanjingJiangsu 210000China

The process of riming significantly impacts the microphysical characteristics of *** study uses aircraft and radar observation data in stratiform clouds with convection embedded that occurred in the central and southern regions of North China on 22 May *** microphysical structural characteristics and processes near the embedded convection core and in the stratiform cloud are analyzed *** attention is given to the effect of riming on the microphysical properties near the upper boundary of the melting layer and to the factors influencing riming *** collaborative observations reveal that the particle size distributions observed near the convection core and in the stratiform region are close,while the particle properties like habit and riming degree are quite *** the melting layer,larger plate-like ice particles and supercooled water droplets(D>50μm)are more abundant near the convective core,leading to higher collision efficiencies between ice particles and supercooled water *** fluctuation amplitudes of vertical airflow near the convective core also contribute to the increased riming activity and the formation of more heavily rimed particles,such as ***,in situ measurements from airborne probes also revealed that above the melting layer,the riming process involves two stages:the mass of snow crystals grows as supercooled droplets merge internally without changing size,followed by external freezing that significantly enlarges the crystals.

关键词： riming collision efficiency airflow fluctuation particle habit aircraft measurement

Nestlings of two parrotbill species can independently evaluate the presenceof predators based on acoustic cues

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Avian Research 2025年第01期 83-88页

作者： Jiaojiao Wang Peng Pan Haijie Zhang Laikun Ma Qindong Zhou Longwu Wang Jianhua hou College of Life Science Hebei University Engineering Research Center of Ecological Safety and Conservation in Beijing-Tianjin-Hebei (xiong'an New Area) of MOE Hebei Basic Science Center for Biotic Interaction Department of Biology and Food Science Hebei Normal University for Nationalities School of Life Sciences Guizhou Normal University

Nest predation is the leading cause of reproductive failure in birds and a major driving force in the evolution of anti-predation strategies. Current studies on the anti-predation strategies of birds driven by predation pressure have mainly focused on adults. However, the detection and behavioral responses of nestlings toward predation risk require further investigation. In this study, we examined nestling responses to predator sounds. Two species of nestlings, the Reed Parrotbill(Paradoxornis heudei) and Vinous-throated Parrotbill(Sinosuthora webbiana),were exposed to the Sparrowhawk(Accipiter nisus, less common) and Oriental Magpie(Pica serica, more common), which are predator species, the Oriental Turtle Dove(Streptopelia orientalis), which is a commonly found harmless species, and background noise. Our findings revealed that compared to pre-playback of natural begging and playback of background noise and Oriental Turtle Dove sounds, playback of the two predator types decreased the total begging time and total number of calls of the two nestlings species, with the calls of the Sparrowhawk leading to greater suppression of nestling begging behavior than those of the Oriental ***, our results indicated that these nestlings were able to distinguish predators from harmless species based on auditory cues.

关键词：

ARTIFICIAL BOUNDARY METHOD FOR THE THREE-DIMENSIONAL EXTERIOR PROBLEM OF ELASTICITY

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Journal of Computational Mathematics 2005年第6期23卷 603-618页

作者： hou-de Han Chun-xiong Zheng Department of Mathematical Sciences Tsinghua University Beijing 100084 China Department of Mathematics University of Science and Technology of China Hefei 230026 China

The exact boundary condition on a spherical artificial boundary is derived for the three-dimensional exterior problem of linear elasticity in this paper. After this boundary condition is imposed on the artificial boundary, a reduced problem only defined in a bounded domain is obtained. A series of approximate problems with increasing accuracy can be derived if one truncates the series term in the variational formulation, which is equivalent to the reduced problem. An error estimate is presented to show how the error depends on the finite element discretization and the accuracy of the approximate problem. In the end, a numerical example is given to demonstrate the performance of the proposed method.

关键词： artificial boundary method unbounded domains elasticity