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Desflurane anesthesia compared with total intravenous anesthesia on anesthesia-controlled operating room time in ambulatory surgery following strabotomy:a randomized controlled study

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Chinese Medical Journal 2020年第7期133卷 779-785页

作者： Yan-Ling Zhu Wei-Hua Shen Qian-Ru Chen hui-jin ye jing-Xia Huang Ying Kang Wei Chi Xiao-Liang Gan Department of Anesthesiology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhouGuangdong 510060China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhouGuangdong 510060China

Background:Ophthalmic ambulatory surgery is preferred to be performed under general anesthesia either by total intravenous anesthesia(TIVA)or by inhalational anesthesia to increase the patient ***,anesthesia-controlled time(ACT)can cause increased non-operative operating room(OR)time which may adversely affect the ORs *** study was aimed to compare the ACT of desflurane with that of propofol-remifentanil in strabismus ambulatory ***:From November 2016 to December 2017,a total of 200 strabismus patients(aged 18-60 years old,and scheduled for elective ambulatory surgery at Zhongshan Ophthalmic Center)were randomly assigned to receive either propofol-based TIVA(group TIVA)or desflurane anesthesia(group DES)for maintenance of *** primary outcome was the extubation *** outcomes included surgical time,anesthetic time,OR exit time,and Phase I and II recovery *** intraoperative incidences of hypotension,bradycardia and oculocardiac reflex(OCR),and the incidences of any post-operative complications were ***-Whitney U test and Chi-square or Fisher exact tests were used to compare the two ***:We found that the extubation time(5.5[3.9-7.0]vs.9.7[8.5-11.4]min,Pyed shorter OR exit time as compared with that in the TIVA group(7.3[5.5-8.7]vs.10.8[9.3-12.3]min,P<0.001).The patients using desflurane exhibited more stable hemodynamics during surgery than the patients using propofol-based TIVA,as demonstrated by lower incidences of hypotension(1%vs.22%,P<0.001),bradycardia(2%vs.13%,P=0.002),and OCR(17%vs.44%,P<0.001).Conclusion:DES enhanced the ophthalmic OR efficiency by reducing the extubation time and OR exit time,and provided more stable hemodynamics intra-operatively than TIVA in patients undergoing strabismu

关键词： Desflurane Propofol Operating rooms Efficiency Strabismus Ambulatory surgery

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： jin-Peng Wang Guo-Cui Mao hui-Lin Jiang Bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao jing-Wen Li hui ye Xue-Zhi Zhang Jian-Xiang Liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

Vector meson's spin alignments in high energy reactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 5-20页

作者： jin-hui Chen Zuo-Tang Liang Yu-Gang Ma Xin-Li Sheng Qun Wang Key Laboratory of Nuclear Physics and Ion-beam Application (MoE) Institute of Modern PhysicsFudan University Institute of Frontier and Interdisciplinary Science Key Laboratory of Particle Physics and Particle Irradiation (MOE)Shandong University INFN-Firenze Department of Modern Physics University of Science and Technology of China School of Mechanics and Physics Anhui University of Science and Technology

The global spin alignment of vector mesons has been observed by the STAR collaboration at the Relativistic Heavy Ion Collider （RHIC） at Brookhaven National Laboratory （BNL）.It provides a unique opportunity to probe the correlation between the polarized quark and antiquark in the strongly coupled quark-gluon plasma （sQGP） produced in relativistic heavy ion collisions,opening a new window to explore the properties of s *** addition,spin alignments of vector mesons have also been observed in other high-energy particle collisions such as e+e-annihilations at high energies where hadron production is dominated by quark fragmentation *** results obtained are quite different from those obtained in heavy ion collisions where quark coalescence/combination mechanism dominates suggesting strong dependence on hadronization *** comprehensive studies in different hadronization processes are *** this article,we present a brief review of theoretical and experimental advances in the study of vector meson’s spin alignments in a variety of high-energy particle collisions,with emphasis on hadronization mechanisms.

关键词： vector meson spin alignment global polarization relativistic heavy ion collisions fragmentation

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

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Neural Regeneration Research 2025年第8期20卷 2199-2217页

作者： Zi ye Runqing Liu Hangxing Wang Aizhen Zuo Cen jin Nan Wang huiqi Sun Luqian Feng Hua Yang The Clinical Medical College Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Infectious Diseases Department of Internal MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina School of Medical Imaging Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Gastroenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina The Second Clinical Medical College Lanzhou UniversityLanzhouGansu ProvinceChina Department of Neurosurgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina

Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion *** studies have elucidated the neuroprotective role of the sirtuin protein family(Sirtuins)in modulating cerebral ischemia-reperfusion ***,the potential of utilizing it as a novel intervention target to influence the prognosis of cerebral ischemia-reperfusion injury requires additional *** this review,the origin and research progress of Sirtuins are summarized,suggesting the involvement of Sirtuins in diverse mechanisms that affect cerebral ischemia-reperfusion injury,including inflammation,oxidative stress,blood-brain barrier damage,apoptosis,pyroptosis,and *** therapeutic avenues related to Sirtuins that may improve the prognosis of cerebral ischemia-reperfusion injury were also investigated by modulating Sirtuins expression and affecting representative pathways,such as nuclear factor-kappa B signaling,oxidative stress mediated by adenosine monophosphate-activated protein kinase,and the forkhead box *** review also summarizes the potential of endogenous substances,such as RNA and hormones,drugs,dietary supplements,and emerging therapies that regulate Sirtuins *** review also reveals that regulating Sirtuins mitigates cerebral ischemia-reperfusion injury when combined with other risk *** Sirtuins show promise as a potential target for the treatment of cerebral ischemiareperfusion injury,most recent studies are based on rodent models with circadian rhythms that are distinct from those of humans,potentially influencing the efficacy of Sirtuinstargeting drug ***,this review provides new insights into the role of Sirtuins in the pathology and treatment of cerebral ischemia-reperfusion injury.

关键词： apoptosis autophagy blood-brain barrier dietary supplements drug hormones inflammation neuroprotection oxidative stress prognosis pyroptosis reperfusion injury risk factors RNA therapeutics

抗菌药物与手术治疗单纯性急性阑尾炎的系统评价

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重庆医学 2017年第9期46卷 1235-1239页

作者：靳艳文叶辉李富宇熊先泽程南生四川大学华西医院胆道外科成都610041

目的评价抗菌药物保守治疗与阑尾切除术治疗单纯性急性阑尾炎(AA)的疗效与安全性。方法计算机检索中国生物医学文献数据库(CBM,1978年至2015年6月)、中国期刊全文数据库(CNKI,1979年至2015年6月)、Medline(1950年至2015年6月)、Pubmed(1... 详细信息

目的评价抗菌药物保守治疗与阑尾切除术治疗单纯性急性阑尾炎(AA)的疗效与安全性。方法计算机检索中国生物医学文献数据库(CBM,1978年至2015年6月)、中国期刊全文数据库(CNKI,1979年至2015年6月)、Medline(1950年至2015年6月)、Pubmed(1950年至2015年6月)、Embase(1970年至2015年6月)和Cochrane图书馆(2015年第2期),收集抗菌药物保守治疗与阑尾切除术治疗单纯性AA的随机对照试验(RCT),按照Cochrane系统评价方法,由两名研究者独立地对符合纳入标准的试验进行资料提取,并对纳入文献进行质量评估和对提取的有效数据进行Meta分析。结果纳入6个RCTs,共1 510例单纯性AA患者符合纳入标准,其中使用抗菌药物治疗的有767例,采用阑尾切除术治疗的有743例。与手术治疗比较,抗菌药物保守治疗的有效率降低了25.00%(RD=-0.25,95%CI:-0.35^-0.14),复发率升高48.43倍(OR=48.43,95%CI:16.94~138.44),劳动力丧失时间缩短1.52d(MD=-1.52,95%CI:-3.02^-0.02),但在并发症的发生率(RD=-0.06,95%CI:-0.15~0.03)、疼痛时间(MD=-0.76,95%CI:-3.31~1.79)、住院时间(MD=4.60,95%CI:-0.89~10.09)、病假时间(MD=-2.39,95%CI:-5.62~0.84)方面两种治疗方法比较,差异无统计学意义(P>0.05)。结论阑尾切除术可能仍是治疗单纯性AA的金标准方法。

关键词：抗菌药阑尾切除术阑尾炎随机对照试验 Meta分析

An Efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai Zhang Liping Ding Liyun Wu Songfeng E Qian He Nanyang Wang hui Zuo Zhengyang Zhou Feng Ding Yue Hu jin Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of Electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials Engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular Engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

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分支结构参数变化对柔性转子动力特性的影响

安徽理工大学学报（自然科学版） 2017年第4期37卷 59-65页

作者：焦旭东何金辉夏冶宝西安航空职业技术学院陕西西安710089 陕西中圣环境科技发展有限公司陕西西安710072 西北工业大学振动工程研究所陕西西安710072

针对动力涡轮转子中存在的悬臂分支结构,研究了柔性转子动力学特性随分支结构参数的变化。建立了带分支转盘系统的转子动力学模型,利用拉格朗日方程推导了其运动微分方程,采用数值方法对不同法兰盘偏置量、分支轴长度、弹性支承刚度下... 详细信息

针对动力涡轮转子中存在的悬臂分支结构,研究了柔性转子动力学特性随分支结构参数的变化。建立了带分支转盘系统的转子动力学模型,利用拉格朗日方程推导了其运动微分方程,采用数值方法对不同法兰盘偏置量、分支轴长度、弹性支承刚度下转子系统的临界转速、振型和不平衡响应进行了计算和比较。研究表明,改变分支结构参数对系统不同振型临界转速的影响不同,通过降低法兰盘偏置量、增大分支轴长度,可以显著地减小转子的弯曲临界转速,同时降低转子的抗弯刚度,造成涡轮盘处的不平衡响应增大。

关键词：转子分支结构建模动力学特性

A study of the evolution of nanoparticle dynamics in a homogeneous isotropic turbulence flow via a DNS-TEMOM method

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Journal of Hydrodynamics 2020年第6期32卷 1091-1099页

作者： Hong-ye Ma Ming-zhou Yu Han-hui jin College of Mechanical and Electrical Engineering China Jiliang UniversityHangzhou310018China Institute of Fluid Engineering Zhejiang UniversityHangzhou310027China

In this article,a coupling of the direct numerical simulation(DNS)and the population balance modeling(PBM)is implemented to study the effect of turbulence on nanoparticle dynamics in homogenous isotropic turbulence(HIT).The DNS is implemented based on a pseudo-spectral method and the PBM is implemented using the Taylor-series expansion method of *** result verifies that coagulation due to turbulent shear force has a bigger impact on the evolution of number concentration,polydispersity,and average diameter of nanoparticles than Brownian coagulation in the *** Reynolds number plays an important role in determining the number concentration,polydispersity,and average diameter of nanoparticles,and these quantities change more rapidly with an increase of Reynolds *** is also found that the initial geometric standard deviation slows down the evolution of particle dynamics,but almost has no influence on the polydispersity of nanoparticles.

关键词： nanoparticle dynamics Turbulence pseudo-spectral method Taylor-series expansion method of moments