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Treating aplasia cutis congenita in a newborn with the combination of ionic silver dressing and moist exposed burn ointment: A case report

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World Journal of Clinical Cases 2019年第17期7卷 2611-2616页

作者： Guo-Feng Lei Jun-Ping Zhang Xiao-Bing Wang Xiao-Li You jin-ya gao Xiao-Mei Li Mei-Ling Chen Xiu-Qin Ning Jiang-Li Sun Department of Neonatal Intensive Care Unit Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina Department of Intensive Care Unit Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina Reproductive endocrine center Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina

BACKGROUND Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis,dermis and even subcutaneous tissue (including muscle and bones).First reported by Cordon in 1767,ACC is a rare disease with a low incidence of 1/100000 to 3/***,there are 500 cases reported *** can be accompanied by other *** onset mechanism of the disease remains unknown but is thought to be correlated to factors such as genetics,narrow uterus,foetal skin and amniotic membrane adhesion,use of teratogenic drugs in early pregnancy and viral *** SUMMARY In August 2018,we treated a newborn with ACC on the left lower limbs using a combination of ionic silver dressing and moist exposed burn ointment (MEBO) and achieved a satisfactory treatment *** skin defects were observed on the external genitals and on areas from the left foot to 3/4 of the upper left *** tissue and blood vessels were observed in the regions with skin *** following treatments were ***,the wound was rinsed with 0.9% sodium chloride solution followed by disinfection with povidone-iodine *** then MEBO was applied to the wound at a thickness of approximately 1 *** applying ionic silver dressing,the wound was covered with sterile *** wound dressing was replaced every 2-3 *** the 4-mo follow-up,the treatment outcome was *** was minimal scar tissue formation,and limb function was not *** The combination of ionic silver dressing and MEBO to ACC is helpful.

关键词： Aplasia cutis congenita Newborns Ionic silver dressing Moist exposed burn ointment

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Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li Zhen Ma jin-Hua gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High Magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

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融合粗糙数据推理的卷积记忆网络文本情感分析

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科学技术与工程 2022年第29期22卷 12936-12944页

作者：钟娜周宁靳高雅兰州交通大学电子与信息工程学院兰州730070

为解决现有情感分类算法在特征提取中缺乏对语义关联规则的运用,以及在分词后产生大量与情感预测无关的词,导致挖掘出的特征不具代表性的问题。提出一种融合粗糙数据推理的卷积记忆网络情感分析模型。首先,通过上下文信息使用粗糙数据... 详细信息

为解决现有情感分类算法在特征提取中缺乏对语义关联规则的运用,以及在分词后产生大量与情感预测无关的词,导致挖掘出的特征不具代表性的问题。提出一种融合粗糙数据推理的卷积记忆网络情感分析模型。首先,通过上下文信息使用粗糙数据推理获得文本的情感词集Word2Vec词向量表示,并融合FastText词向量来改进特征向量嵌入层;其次,使用卷积神经网络(convolutional neural network, CNN)拼接双向长短期记忆网络(bi-directional long short-term memory, BiLSTM)提取更深层次的情感特征;最后,加入Attention机制计算权重,筛选显著重要特征。在两个数据集上的实验结果显示,该模型的情感分类准确率与F_(1)值最高可达到84.66%和85.1%,较基线模型中的最高值分别高出2.04%和3.1%,有效提升了情感分类的预测能力。

关键词：粗糙数据推理词向量卷积记忆网络情感分析

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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin Liu Jian Zhang ya gao Shuyue Li Cui Chang Xiang Liu Guofeng yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li Jian Xiang Lu Qiu Xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao gao Wenlong Liu Dan Xiao Zhaoyu jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

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Assessing the corrosion protection property of coatings loaded with corrosion inhibitors using the real-time atmospheric corrosion monitoring technique

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 119-126页

作者： Xiaoxue Wang Lulu jin jinke Wang Rongqiao Wang Xiuchun Liu Kai gao jingli Sun Yong Yuan Lingwei Ma Hongchang Qian Dawei Zhang School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Institute of Space Long March Vehicle Beijing 100076China National Materials Corrosion and Protection Data Center University of Science and Technology BeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal ***,limited studies have applied ACM to the corrosion protection properties of organic *** study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over *** with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in *** the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy *** trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface *** alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic *** with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.

关键词： atmospheric corrosion monitoring technology corrosion inhibitor coating carbon steel corrosion protection

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Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

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Neural Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui Kang Xuan Cheng Hui gao Shujia Huo Haiwei Xu Key Lab of Visual Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assume responsibility for spontaneous retinal regeneration,wherein endogenous Müller glia undergo proliferation,transform into Müller glia-derived progenitor cells,and subsequently regenerate the entire retina with restored ***,Müller glia in the mouse and human retina exhibit limited neural reprogramming.Müller glia reprogramming is thus a promising strategy for treating neurodegenerative ocular disorders.Müller glia reprogramming in mice has been accomplished with remarkable success,through various *** in molecular,genetic,epigenetic,morphological,and physiological evaluations have made it easier to document and investigate the Müller glia programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial toward exploring factors that will improve Müller glia reprogramming efficiency,and for developing novel Müller glia reprogramming *** review describes recent progress in relatively successful Müller glia reprogramming *** also provides a basis for developing new Müller glia reprogramming strategies in mice,including epigenetic remodeling,metabolic modulation,immune regulation,chemical small-molecules regulation,extracellular matrix remodeling,and cell-cell fusion,to achieve Müller glia reprogramming in mice.

关键词： cell fusion chemical small-molecules epigenetic extracellular matrix immune metabolic mice Müller glia neurodegenerative diseases reprogramming retina regeneration

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Grain and dendrite refinement of A356 alloy with Al-Ti-C-RE master alloy

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Rare Metals 2013年第1期32卷 12-17页

作者： Hong-Liang Zhao jin-Sheng Yue ya gao Kang-Rong Weng College of Materials Science and Engineering Zhengzhou University

Commercial A356 alloy was refined with a homemade A1-5Ti-0.25C-2RE master alloy, and the microstructure and macrostructure of the refined alloy were investigated. The results show that the grain refining effect of A356 is poor by the addition level of 0.5 wt% master alloy, but when the level reaches 3.0 wt% the grain can get a satisfactory refining effect. Dendrite of A356 can be effectively refined by addition of 0.5 wt% master alloy; however, the refining effect is not significantly improved by further increasing the addition of master alloy. Grain and dendrite refining effects are compared in this article, and the results show that the grain and dendrite exhibit different refining effects with the same addition level of master alloy. Dendrite is easier to reach the optimal refining effect than grain.

关键词： A1-Ti-C-RE A356 Grain refiner Secondary dendrite arm spacing (SDAS)

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng gao Yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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主体结构荷载可控的新型组合式防护结构(Ⅱ)：影响因素及设计理念

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爆炸与冲击 2025年第1期45卷 011101-1-011101-12页

作者：方秦高矗孔祥振杨亚陆军工程大学爆炸冲击防灾减灾国家重点实验室江苏南京210007 内蒙古财经大学财政税务学院内蒙古呼和浩特010070

为明确泡沫混凝土厚度和强度对组合式防护结构抗爆性能的影响，充分发挥和合理利用泡沫混凝土良好的消波特性，首先通过试验及数值模拟探讨不同泡沫混凝土厚度和强度对组合式防护结构抗爆性能的影响，并分析分层梯度泡沫混凝土在爆炸波... 详细信息

为明确泡沫混凝土厚度和强度对组合式防护结构抗爆性能的影响，充分发挥和合理利用泡沫混凝土良好的消波特性，首先通过试验及数值模拟探讨不同泡沫混凝土厚度和强度对组合式防护结构抗爆性能的影响，并分析分层梯度泡沫混凝土在爆炸波作用下的消波特性。然后将组合式防护结构与采用中粗砂为分配层的传统成层式结构进行对比分析验证其优越性，在此基础上，总结凝练出组合式防护结构的主体结构荷载可控的设计理念。结果表明，利用泡沫混凝土材料较长的屈服平台和较低的波阻抗，以泡沫混凝土作为能量调控层，通过设计泡沫混凝土强度等级（密度等级）和厚度以及采用多层梯度泡沫混凝土，可使得作用于主体结构上的爆炸荷载峰值恰为泡沫混凝土屈服强度，实现对主体结构上荷载的可控设计，有效解决了中粗砂为分配层的传统成层式结构不易控制作用于主体结构上荷载的问题。研究结果可为抗新型钻地弹的防护设计提供重要参考。

关键词：泡沫混凝土组合式防护结构可控设计爆炸波消波

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