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Diagnostic accuracy of administrative database for bile duct cancer by ICD-10 code in a tertiary institute in Korea

Hepatobiliary & Pancreatic Diseases International 2020年第6期19卷 575-580页

作者： Young-Jae Hwang Seon Mee park soomin Ahn Jongchan Lee Young soo park Nayoung Kim Department of Internal Medicine Seoul National University Bundang HospitalSeongnamKorea Department of Internal Medicine Chungbuk National University College of Medicine and Medical Research InstituteCheongjuKorea Department of Pathology Seoul National University Bundang HospitalSeoungnamKorea Department of Internal Medicine and Institute of Liver Research Seoul National University College of MedicineSeoulKorea Tumor Microenvironment Global Core Research Center Seoul National UniversitySeoulKorea

Background:Administrative database provides valuable information for large cohort studies,especially when tissue diagnosis is rather difficult such as the diagnosis for bile duct cancer(BDC).The aim of this study was to evaluate the diagnostic accuracy of administrative database for BDC by International Classification of Diseases(ICD)-10 codes in a tertiary ***:BDC and control groups were collected from 2003 to 2016 at Seoul National University Bundang *** of BDC were identified in the National Health Insurance Service(NHIS)database by ICD 10-code supported by V *** control group was selected from cases without ICD-10 codes for BDC.A definite or possible diagnosis was defined according to pathologic *** records,images,and pathology reports were analyzed to evaluate ICD-10 codes for ***,specificity,positive predictive value,and negative predictive value for BDC were analyzed according to diagnostic criteria and cancer ***:A total of 1707 patients with BDC and 1707 controls were *** those with BDC,1320(77.3%)were diagnosed by definite ***(99.4%)of them had *** of definite diagnosis was the highest for ampulla of Vater(88.9%),followed by that for extrahepatic(84.9%)and intrahepatic(68.3%)*** positive cases commonly had hepatocellular *** overall diagnosis of BDC,sensitivity,specificity,positive predictive value,and negative predictive value were 99.94%,98.33%,98.30%,and 99.94%,*** accuracies were similar regardless of diagnostic criteria or tumor ***:Administrative database for BDC collected according to ICD-10 code with V code shows good accuracy.

关键词： National Health Insurance Service Bile duct cancer ICD-10

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Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1β expression

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Acta Pharmaceutica Sinica B 2020年第3期10卷 462-474页

作者： Han Saem Son Jiae Lee Hye In Lee Narae Kim You-jin Jo Gong-Rak Lee Seong-Eun Hong Minjeong Kwon Nam Young Kim Hyun jin Kim jin Ha park soo Young Lee Woojin Jeong Department of Life Science and the Research Center for Cellular Homeostasis Ewha Womans UniversitySeoul 03760South Korea

Bone diseases such as osteoporosis and periodontitis are induced by excessive osteoclastic activity,which is closely associated with ***(BA)has been used as a cytokine-suppressive or non-steroidal anti-inflammatory drug that inhibits the production of proinflammatory cytokines or ***,its role in osteoclast differentiation and function remains ***,we explored the role of BA in regulating osteoclast differentiation and elucidated the underlying *** inhibited osteoclast differentiation and strongly suppressed interleukin-1β(IL-1β)*** inhibited osteoclast formation and bone resorption when added to bone marrowderived macrophages and differentiated osteoclasts,and the inhibitory effect was reversed by IL-1β*** reporter assay and the inhibitor study of IL-1βtranscription suggested that BA inhibited nuclear factor-κB and activator protein-1 by regulating IκB kinase,extracellular signal regulated kinase and P38,resulting in the down-regulation of IL-1β*** also promoted osteoblast ***,BA protected lipopolysaccharide-and ovariectomy-induced bone loss in mice,suggesting therapeutic potential against inflammation-induced bone diseases and postmenopausal osteoporosis.

关键词： Benzydamine Osteoclast Bone Interleukin-1β Nuclear factor-κB Activator protein-1

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Rational design of ultrafine FeSe_(2) nanocrystals emb e dde d within hollow mesoporous carbon bowls for potassium-ion batteries with long-term cycling stability and high volumetric capacity

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Journal of Materials Science & Technology 2023年第12期143卷 129-139页

作者： Yu jin Jang Hong Geun Oh Seung-Keun park Department of Advanced Materials Engineering Chung-Ang University4726Seodong-daeroDaedeok-myeonAnseong-siGyeonggi-do 17546Republic of Korea

Hollow structures are commonly used to alleviate the mechanical stress on electrode materials and to provide more active sites in potassium-ion batteries(KIBs).Nevertheless,the excessive internal voids within these structures significantly reduce the packing density of particles,resulting in a relatively low volumetric energy density of the fabricated electrodes,which is undesirable for practical *** designed a hollow mesoporous carbon bowl embedded with ultrafine bis(selanylidene)iron(FeSe 2)nanocrystals(FeSe 2@HMCB)via a controllable impregnation method and subsequent selenization pro-cess for high-performance *** as-obtained FeSe 2@HMCB can inherit the advantages of conventional hollow carbon-based composites,such as alleviation of volume variation in active materials,abundant ion storage sites,and high electrical ***,the bowl structure has a higher pack-ing density than the conventional hollow structure,resulting in a significant increase in the volumet-ric energy density of the fabricated *** of these advantages,the FeSe 2@HMCB exhibits a high,stable reversible capacity of 326 mA h g^(-1) even after 1000 cycles at 0.5 A g^(-1),and excellent rate capacities(182 mA h g^(-1) at 3.0 A g^(-1)).Compared with the hollow structured counterpart,the vol-umetric capacity(mA h cm−3)of FeSe 2@HMCB increased by 60%.Furthermore,a full cell consisting of FeSe 2@HMCB//Prussian blue(PB)exhibits excellent electrochemical performance(99 mA h g^(-1) after 100 cycles at 0.1 A g^(-1)).

关键词： Potassium-ion batteries Iron selenide Bowl-like structure Mesoporous carbon Anode material

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EXPERIMENTAL AND NUMERICAL STUDY FOR HYDRODYNAMIC CHARACTERISTICS OF AN OSCILLATING HYDROFOIL

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Journal of Hydrodynamics 2008年第3期20卷 280-287页

作者： LIU Zhen HYUN Bcom-soo KIM Moo-rong jin Ji-yuan College of Engineering Ocean University of China Qingdao 266100 China College of Ocean Science and Technology Korea Maritime University Busan 606791 Korea Maritime and Ocean Engineering Research Institute Daejeon 305-343 Korea

The present article reports the experimental Particle Image Velocimetry （PIV） investigation and the corresponding numerical simulation results about the water flow over the oscillating hydrofoil and its unsteady dynamic characters. The experimental study focuses on the effect of mean angles of attack. The comparison between the PIV results and numerical prediction about the flow field using Fluent well demonstrates the capability of CFD on the simulation of the water flow around the pitching hydrofoil. The numerical results indicate that the forced oscillating frequencies have evident effects on the flow separation and vortex shedding. The simulations about the hydrodynamic drag and lift coefficients were also performed.

关键词： Particle Image Velocimetry (PIV) oscillating hydrofoil numerical simulation Fluent flow field force characteristics

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Microstructure and Mechanical Properties of TiB-Containing Al–Zn Binary Alloys

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Journal of Materials Science & Technology 2016年第7期32卷 653-659页

作者： Sang-soo Shin Gil-Yong Yeom Tae-Yang Kwak Ik-Min park Department of Materials Science and Engineering Pusan National University Busan 609-735 Republic of Korea Liquid Processing & Casting Technology R&BD Group Korea Institute of Industrial Technology Incheon 21999 Republic of Korea

The microstructure and mechanical properties of newly developed Al-35Zn cast alloys with TiB refiner addition were evaluated by X-ray diffractometry, optical microscopy, and scanning electron microscopy coupled with energy dispersive spectrometry. The microstructure of these alloys featured α-Al den- drites surrounded by AI-Zn （α ＋ rI） eutectic structures. After the addition of TiB refiner, the alloy grain sizes decreased, and its morphology abruptly changed from dendritic to equiaxed grains. Such an im- proved microstructure of the modified alloys was accompanied by a significant increase in the tensile strength and elongation percentage compared to those of the AI-Zn or Zn-Al-based alloys. The results showed that with the increase of TiB content up to 0.05%, the morphology of α-Al dendrites and α ＋ T1 phases changed from coarse dendrite and lamellar structures into independent and fine ones. Based on these results, the effect of TiB refiner addition on the microstructure and mechanical properties of the AI-35Zn binary alloys was investigated.

关键词： Al-Zn(-Cu) alloyEutectic structureHigh strengthTiB2

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Cavernous mesenteric lymphangiomatosis mimicking metastasis in a patient with rectal cancer:A case report

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World Journal of Gastroenterology 2009年第31期15卷 3947-3949页

作者： Seong Su Hwang Hyun Joo Choi soo Youn park Department of Radiology St.Vincent's HospitalCollege of MedicineThe Catholic University of Korea Department of Pathology St.Vincent's HospitalCollege of MedicineThe Catholic University of Korea

Lymphangioma usually occurs in children and usually involves the skin. Mesenteric lymphangioma is extremely rare in adults. Typically, lymphangioma appears on computed tomography (CT) as a lower attenuation of a cystic mass, however, some cases appear to be a solid mass. We describe the CT and 18F-FDG positron emission tomography/CT appearance in a case of jejunal and mesenteric cavernous lymphangi-omatosis mimicking metastasis in an adult patient with rectal cancer.

关键词： Lymphangioma Lymphangiomatosis Mesentern/ Small intestine Computed tomography 18F-FDG positron emission tomography/computed tomography

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Application of signal processing techniques to the detection of tip vortex cavitation noise in marine propeller

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Journal of Hydrodynamics 2013年第3期25卷 440-449页

作者： LEE Jeung-Hoon HAN Jae-Moon park Hyung-Gil SEO Jong-soo Samsung Ship Model Basin (SSMB) Marine Research Institute Samsung Heavy Industries Science TownDaejeon 305-380 Korea

The tip vortex cavitation and its relevant noise has been the subject of extensive researches up to now. In most cases of experimental approaches, the accurate and objective decision of cavitation inception is primary, which is the main topic of this paper. Although the conventional power spectrum is normally adopted as a signal processing tool for the analysis of cavitation noise, a faithful exploration cannot be made especially for the cavitation inception. Alternatively, the periodic occurrence of bursting noise induced from tip vortex cavitation gives a diagnostic proof that the repeating frequency of the bursting contents can be exploited as an indication of the inception. This study, hence, employed the Short-Time Fourier Transform （STFT） analysis and the Detection of Envelope Modulation On Noise （DEMON） specmma analysis, both which are appropriate for finding such a repeating frequency. Through the acoustical measurement in a water tunnel, the two signal processing techniques show a satisfactory result in detecting the inception of tip vortex cavitation.

关键词： tip vortex cavitation inception Short-Time Fourier Transform (STFT) Detection of Envelope Modulation On Noise(DEMON)

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The effects of Y pre-alloying on the in-situ dispersoids of ODS Co Cr Fe Mn Ni high-entropy alloy

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Journal of Materials Science & Technology 2021年第26期85卷 62-75页

作者： SeungHyeok Chung Bin Lee soo Yeol Lee Changwoo Do Ho jin Ryu Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Manufacturing Technology Office Korea Institute for Rare MetalKorea Institue of Industrial TechnologyGet-Pearl TowerGaetbeol-ro 12Yeonsu-guIncheon 21999Republic of Korea Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Neutron Scattering Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Oxide dispersion strengthened CoCrFeMnNi high-entropy alloys(ODS-HEAs)were prepared using two different powder preparation methods classified by yttrium addition strategy to investigate the effects of in-situ and ex-situ oxide dispersoid formation on the microstructure and mechanical *** micro structural analysis was carried out by X-ray diffraction(XRD),electron backscattered diffraction(EBSD),high-resolution transmission electron microscopy(HRTEM),atom probe tomography(APT),and small-angle neutron scattering(SANS).Cryo-milled powder analysis,grain structure evolution after spark plasma sintering,dispersoid characteristics,and matrix/dispersoid interface structure analysis of the insitu and ex-situ dispersoids within the high-entropy alloy(HEA)matrix were *** in-situ dispersoid formation was dominantly observed in the Y-alloyed ODS-HEA through the construction of a coherent interface relationship with complex chemical composition,leading to an increase in the Zener pinning forces on the grain boundary ***-HEA with in-situ oxide dispersoids enhanced the formation of ultrafine-grained structures with an average diameter of 330 nm at a sintering temperature of 1173 *** study shows that the Y pre-alloying method is efficient in achieving fine coherent dispersoids with an ultra fine-grained structure,resulting in an enhancement of the tensile strength of the CoCrFeMnNi HEA.

关键词： Oxide dispersion strengthened(ODS)alloy High-entropy alloy In-situ oxide dispersoid formation Microstructure Mechanical property

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Portable nano probe for micro/nano mechanical scratching and measuring

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 205-209页

作者： Woo-park JEONG Chang-Choi soo Cho HYUN Woo-Lee DEUG Department of Mechanical Design Engineering Chosun University Department of Nano Fusion Technology Pusan National University Department of Nano-mechatronics Engineering Pusan National University

A nano probe system which can measure precise contact force in mN scale was demonstrated. The nano probe micro parts or optical parts in nanometer range resolution and scratch was originally designed for on-machine measuring applications and one kind of contact type measuring probes was designed for miniaturized or microfactory system. It ideally should be of small size and able to measure surface topography in nanometer scale. A commercial capacitive displacement sensor was proposed. It was a new concept in nano probe systems which can measure the displacement of shaft driven by the variation of surface topography. The nano probe mainly consisted of three parts： a capacitive displacement sensor, a porous type air slide and a contact probe part with various tip radiuses. The porous type air slide assured the shaft slided smoothly with controllable normal force in mN scale and had high positioning accuracy. The probe part which was directly in contact with target surface, can be applied to micro/nanoscale scratching as well as the measurement of sample topography by a simple tip change.

关键词： nano probe displacement sensor air slide PCD tip

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Fibrillary gelation and dedoping of PEDOT:PSS fibers for interdigitated organic electrochemical transistors and circuits

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npj Flexible Electronics 2022年第1期6卷 330-340页

作者： Young jin Jo soo Young Kim Jeong Hun Hyun Byeonghak park Seunghwan Choy Gyan Raj Koirala Tae-il Kim School of Chemical Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Biomedical Institute for Convergence(BICS) Sungkyunkwan University(SKKU)Suwon 16419Korea

As one of conducting polymers,PEDOT:PSS,is commonly used in organic electronics,especially for bioelectronics due to its advantages such as high electrical and ionic conductivity,solution-processability and *** bioelectronics with the PEDOT:PSS requires advanced techniques to obtain physical/chemical modification of the PEDOT:PSS for improved performance and various *** satisfy these demands,fibrillary gelation of PEDOT:PSS by injection to choline acetate,an ionic liquid,with a constant flow rate was used in this study to make a conductive fiber and improve characteristics of PEDOT:*** fibers by fibrillary gelation showed enhanced electrical conductivity of about 400 S cm^(-1) and volumetric capacitance of about 154 F cm^(−3) which would be strongly beneficial to be utilized for organic electrochemical transistors(OECTs),resulting in a high transconductance of 19 mS in a ***,dedoping of the conductive fibers by PEI(polyethyleneimine)enabled the creation of enhancement-mode *** inverters were then fabricated by connecting depletion and enhancement-mode *** results demonstrate that these conductive fibers and electronic-textiles are suitable candidates for applications in bio-integrated electronics.

关键词： fibers doping digit

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