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Hepatobiliary & Pancreatic Diseases International 2023年第5期22卷 482-489页

作者： jin-shu zeng Jian-Xing zeng Yao Huang jing-Feng Liu jin-Hua zeng Department of Ultrasonic Medical The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China The Liver Center of Fujian Province Fujian Medical UniversityFuzhou 350025China Department of Hepatobiliary Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China Department of Hepatobiliary Surgery Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhou 350005China

Background:There is currently no standard adjuvant treatment proven to prevent hepatocellular carcinoma(HCC)*** studies suggest that postoperative adjuvant transarterial chemoembolization(PA-TACE)is beneficial for patients at high risk of tumor ***,it is difficult to select the *** present study aimed to develop an easy-to-use score to identify these ***:A total of 4530 patients undergoing liver resection were *** risk factors were identified by Cox regression model in the training cohort and the Primary liver cancer big data transarterial chemoembolization(PDTE)scoring system was ***:The scoring system was composed of ten risk factors including alpha-fetoprotein(AFP),albuminbilirubin(ALBI)grade,operative bleeding loss,resection margin,tumor capsular,satellite nodules,tumor size and number,and microvascular and macrovascular *** 5 points as risk stratification,the patients with PA-TACE had higher recurrence-free survival(RFS)compared with non-TACE in>5 points group(P5 points may benefit from PA-TACE.

关键词： Hepatocellular carcinoma Liver resection Adjuvant transarterial chemoembolization Scoring system Risk stratification

Potassium ions and cyano group modified g-C3N4 for effective generation of H2O2 through two-electron oxygen reduction

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Science China Chemistry 2025年第1期 192-200页

作者： Dongying Wang shulan Pu Yongmin Chen Ke Lei Yujie Duan Linjiao Mao Xuhui zeng Xi Luo Yuntao Zhang Yuqin Dong jin Zhong Zhang Yan Sun School of Mechanical Engineering Chengdu University Department of Chemistry and Biochemistry University of California

Potassium ions （K+） doped graphitic carbon nitride （g-C3N4） was prepared by a thermal etching method using potassium hydroxide （KOH） as an ion *** transform infrared spectroscopy （FTIR） and X-ray photoelectron spectroscopy （XPS）results showed that the generation of the cyano group was detected while introducing K+.Under simulated sunlight irradiation,the sample with a K+doping amount of 10%showed the highest hydrogen peroxide （H2O2） generation rate of2,140.2μmol *** apparent quantum yield （AQY） at 400 nm and the solar-to-chemical conversion （SCC） are 4.35%and1.23%,respectively.K+acted as a bridge between g-C3N4layers,which enhanced charge transfer ***,the cyano group enhanced the adsorption capacity of protons （H+） and promoted the yield of *** catalyst exhibited excellent photocatalytic stability based on four-cycle *** addition,a mechanism study showed that superoxide radicals （·O2-）were the most important active species in the reaction *** production of H2O2was achieved through consecutive single-electron *** study deepens the understanding of the oxygen reduction reaction process and opens up a new venue for improving H2O2generation.

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Favorable response of primary pulmonary lymphoepithelioma-like carcinoma to sintilimab combined with chemotherapy: A case report

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World Journal of Clinical Cases 2022年第31期10卷 11617-11624页

作者： shu-Ying zeng jin Yuan Min Lv Department of Oncology The First People's Hospital of Longquanyi District ChengduChengdu 652532Sichuan ProvinceChina

BACKGROUND There is no established treatment for primary pulmonary lymphoepithelioma-like carcinoma(LELC)until *** SUMMARY In this study,the patient responded well to sintilimab combined with paclitaxel and carboplatin,showing no obvious side ***,the values of carbohydrate antigen 15-3(CA15-3)and carbohydrate antigen 72-4(CA72-4)gradually returned to *** Immunotherapy combined with chemotherapy in advanced-stage LELC may be more effective than immunotherapy or chemotherapy ***15-3 and CA72-4 are biomarkers for evaluating therapeutic effects for LELC.

关键词： Lymphoepithelioma-like carcinoma Non-small cell lung cancer Immunotherapy Sintilimab Programmed death-1 Case report

Microscopic Mechanism of the Odd-Even Difference in Moments of Inertia of Superdeformed Bands

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Chinese Physics Letters 2000年第12期17卷 871-873页

作者： LIU shu-Xin YU Lei zeng jin-Yan Department of Physics Peking UniversityBeijing 100871

The large odd-even difference in moments of inertia between the SD bands l95Tl(l,2)and l96Pb(l)is investigated by the particle-number conserving method,in which the blocking effect on pairing is taken into account ***ωvariation of J(2)for the three SD bands are reproduced quite well and the underlying microscopic mechanism is demonstrated *** show that the blocking of the proton[642]5/2 intruder orbital and the excitation of[651]1/2 intruder orbital play crucial roles for the odd-even difference in J(2)’s.

关键词： bands orbital excitation

Spin Assignment of the First Discovered Superdeformed Band 152Dy(1) and Some Superdeformed Bands in Neighboring Nuclei

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Chinese Physics Letters 1999年第9期16卷 632-634页

作者： LIU shu-xin XIN Xiao-bin zeng jin-yan Department of Physics Peking Universityj Beijing 100871

By using various approaches to the spin assignment, including the best-fit-method, the variation of moment of inertia with angular momentum, the bandhead moment of inertia J0 systematics, and the signature systematics, the spin of the lowest level observed in the first discovered superdeformed band 152Dy(1)is definitely predicted to be I0 = 26(Eγ(I0 + 2 → I0) = 602.4 keV), rather than the previously predicted I0 = 22,24, or 25. The spin prediction and properties of some superdeformed bands in the A ~ 150 region are discussed.

关键词： inertia momentum signature

Effect of long-term service on the precipitates in P92 steel

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International Journal of Minerals,Metallurgy and Materials 2018年第8期25卷 913-921页

作者： Yan-ping zeng jin-dou Jia Wen-he Cai shu-qing Dong Zhi-chun Wang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China North China Electric Power Research Institute Co. Ltd.Beijing 100045China

The precipitates in P92 steel after long-term service in an ultra-supercritical unit were investigated by field-emission scanning electron microscopy and transmission electron microscopy and were found to mainly consist of M23 C6 carbides,Laves phase,and MX *** Z-phase was observed.M23 C6 carbides and Laves phase were found not only on prior austenite grain boundaries,martensite lath boundaries,and subgrain boundaries but also in lath interiors,where two types of MX carbonitrides—Nb-rich and V-rich particles—were also observed but the "winged" complexes were hardly *** kind of precipitate within the martensite laths exhibited multifarious morphologies,suggesting that a morphological change of precipitates occurred during long-term *** M23 C6 carbides and Laves phase coarsened substantially,and the latter grew faster than the ***,MX carbonitrides exhibited a relatively low coarsening *** effect of the evolution of the precipitate phases on the creep rupture strength of P92 steel was discussed.

关键词： precipitate P92 steel long-term service ultra supercritical unit

Acupoint Autohemotherapy Attenuates Atopic Dermatitis Lesions by Regulating Th1/Th2 Balance in DNCB-Induced BALB/c Mice

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Chinese Journal of Integrative Medicine 2022年第7期28卷 612-619页

作者： zeng Zhi-wen HUANG jin-quan CHEN Yong YU Xiao ZHU Wei ZHANG Dong-shu School of Traditional Chinese Medicine Southern Medical UniversityGuangzhou 510515China Department of Traditional Chinese Medicine Affiliated Dongguan People's HospitalSouthern Medical UniversityDongguanGuangdong Province 523058China Department of Rheumatology and Immunology Shenzhen People's HospitalThe Second Clinical Medical College of Jinan UniversityShenzhenGuangdong Province 518020China School of Basic Medical Sciences Southern Medical UniversityGuangzhou 510515China Guangzhou Center for Disease Control and Prevention Guangzhou 510515China

Objective: To evaluate the therapeutic effects of acupoint autohemotherapy(A-AHT) on 1-chloro-2,4-dinitrobenzene(DNCB)-induced atopic dermatitis(AD) in mice focusing on regulating T helper 1/T helper 2(Th1/Th2) immune responses. Methods: Thirty BALB/c mice were divided into 5 groups by a random number table, including normal control(NC), AD model(AD), A-AHT, sham A-AHT(sA-AHT), and acupoint injection of normal saline(A-NS) groups, 6 mice per group. Mice were challenged by DNCB for the establishment of experimental AD model. On the 8th day, except for the NC and AD groups, the mice in the other groups received management once every other day for a total of 28 days. For the A-AHT and sA-AHT groups, 0.05 mL of autologous whole blood(AWB) was injected into bilateral Zusanli(ST 36) and Quchi(LI 11) and sham-acupoints(5 mm lateral to ST 36 and LI 11), respectively. The A-NS group was administrated with 0.05 m L of normal saline by acupoint injection into ST 36 and LI 11. Dermatitis severity for dorsal skin of mice was determined using the Severity Scoring of Atopic Dermatitis(SCORAD) every week. The total immunoglobulin E(IgE), interleukin-4(IL-4), and interferon-gamma(IFN-γ) cytokine levels in serum were examined by enzyme-linked immunosorbent assay(ELISA). Spleen Th1/Th2 expression were analyzed via flow cytometry and immunohistochemical assay was used to detect T-box expressed in T cell(T-bet) and GATA-binding protein 3(GATA3) expressions in skin lesions of mice. Results: Compared with the AD group, both A-AHT and sA-AHT reduced the SCORAD index and serum IgE level(P<0.05 or P<0.01);A-AHT, sA-AHT and A-NS down-regulated serum IL-4 level and upregulated IFN-γ/IL-4 ratio(P<0.05 or P<0.01);A-AHT regulated the Th1/Th2 shift specifically and increased the related transcription factors such as T-bet expression and T-bet/GATA3 ratio(P<0.05). Conclusion: A-AHT showed significant effectiveness on the AD model mice, through regulating Th1/Th2 immune responses.

关键词： acupoint autohemotherapy atopic dermatitis Th1/Th2 immunoglobulin E

Kinematics of the high-excitation HH 890 jet in the Rosette Nebula

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Chinese Journal of Astronomy and Astrophysics 2009年第5期9卷 577-584页

作者： jin-zeng Li National Astronomical Observatory Chinese Academy of Sciences Beijing 100012 China

Photoionized jets immersed in HII regions display special properties, which made them a distinctive category of Herbig-Haro （HH） flows. Detailed studies of such jet systems became one of the key issues in our understanding of jet production and evolution. HH 890, initially called the Rosette HH2 jet, is the second photoionized jet discovered in the spectacular HII region of the Rosette Nebula. Contrary to conventional impressions of a jet, its discrete components are found to be unexpectedly broad and spatially detached from the proposed energy source. The jet displays additional unusual features which point to the disputable nature of the system. Here, we investigate the kinematics of the jet through high-quality echelle spectrograms. It is distinctively resolved into a fast component with a mean approaching velocity of-39 km s^-1 with respect to the systemic rest frame and a slow component with radial velocity centered at -9 km s^-1. The slow component indicates an apparently larger dispersion in radial velocity in various emission lines and is likely dissolving at roughly the speed of sound, which favors a photoevaporated origin. The [SII] doublet ratios indicate an electron density of -1.1×10^3 cm^-3 in the collimated jet and ,-9×10^2 cm^-3 in the HII region. This, along with the diffuse appearance of the extensive part of the jet, leads to a dissipation of the jet in the fully ionized medium of Rosette. In addition, time series of photometric observations provide evidence for remarkable light variations of the energy source. Its amplitudes of variation amount to 〉 1 mag in both R and I, which is commensurate with the young evolutionary status of the source as indicated by a red, late type optical spectrum.

关键词： accretion disks -- ISM jets and outflows -- stars formation -- stars premain-sequence

Influence of Quadrupole Pairing on the Variation of j(2) of the Superdeformed Band 194Hg(1)

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Chinese Physics Letters 2000年第2期17卷 94-95页

作者： XIN Xiao-Bin LEI Yi-An LIU shu-Xin zeng jin-Yan Department of Physics Peking UniversityBeijing 100871

Using the particle-number-conserving method we show that the observed downturn of J(2) of the superdeformed band 194Hg(1) can be satisfactorily accounted for, provided that both the monopole and quadrupole pairing int... 详细信息

关键词： satis interaction particle

Rumen fermentation and bacterial communities in weaned Chahaer lambs on diets with different protein levels

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Journal of Integrative Agriculture 2016年第7期15卷 1564-1574页

作者： YANG Chun-tao SI Bing-wen DIAO Qi-yu jin Hai zeng shu-qin TU Yan Feed Research Institute Chinese Academy of Agricultural Sciences/Key Laboratory of Feed BiotechnologyMinistry of AgricultureBeijing 100081P.R.China Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences Huhhot 010000P.R.China

We evaluatedthe effects of diets with different crude protein （CP） levels on growth performance, rumen fermentation and bacterial communities in weaned Chahaer lambs. 128 weaned Chahaer lambs （（20.56±1.43） kg body weight; ram：ewe 1：1） aged （61±1.85） d were randomly alotted to one of four diets with CP content of 11.17% （T1）, 12.06% （T2）, 13.40% （T3） or 14.36% （T4）.Ruminal fermentation parameters were measured and bacterial communities were analysed using PCR-dena-turing gradient gel electrophoresis （PCR-DGGE） and quantitative PCR. The average daily gain and feed utilization efifciency in T3 were higher than those in the other groups （P〈0.05）, although the dry matter intake and metabolizable energy intake were similar. Total volatile fatty acid concentration in the ruminal lfuid of T3 was lower than that of T1 （P=0.011）, T2 （P=0.008） or T4 （P=0.309）. The ammonia nitrogen concentration and acetate/propionate ratio of ruminal lfuid were signiifcantly higher in lambs fed the higher CP diets, whereas the molar concentrations of propionate and butyrate of ruminal lfuid were lower. The rumen bacterial community was similar in T2 and T3 which shown more stable and diverse rumen microbes ecosystem compared with the other groups. The DGGE proifles and phylogenetic tree indicated thatBacteroides uniformis,Clostrid-iumalkalicellulosi,Alkalibaculum *** common bacterium of Chahaer lamb rumen. B. uniformis,***,Saccharofermentanssp. andGracilibacter thermotolerans,which belong to the Bacteroidetes and Firmicutesphyla,were the dominant species in the rumen of lambs fed 13.40% ***,Ruminococcus albus, Ruminococcus lfavefaciensand Butyrivibrio ifbrisolvenswerenot differentin lambs fed different CP diets. Therefore, it could be concluded thatB. uniformis,***,A. *** common bacteria of Chahaer lamb rumen. Furthermore, the dietary CP of 13.04% could improve performance and change rumen fermentati

关键词： dietary crude protein rumen fermentation bacterial diversity weaned lamb PCR-DGGE