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Protein S-acylation,a new panacea for plant fitness

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Journal of Integrative Plant Biology 2024年第10期66卷 2102-2108页

作者： Fei Liu jin-yu lu Sha Li Yan Zhang Frontiers Science Center for Cell Responses College of Life SciencesNankai UniversityTianjin 300071China College of Life Sciences Shandong Agricultural UniversityTai'an 271018China

Protein S-acylation or palmitoylation is a reversible post-translational modification that influences many proteins encoded in plant *** progress in the past 3 years demonstrates that S-acylation modulates subcellular localization,interacting profiles,activity,or turnover of substrate proteins in plants,participating in developmental processes and responses to abiotic or biotic *** this review,we summarize and discuss the role of S-acylation in the targeting of substrate *** highlight complex roles of S-acylation in receptor *** also point out that feedbacks of protein S-acyl transferase by signaling initiated from their substrate proteins may be a recurring ***,the reversibility of S-acylation makes it a rapid and efficient way to respond to environmental *** efforts on exploring these important aspects of S-acylation will give a better understanding of how plants enhance their fitness under ever changing and often harsh environments.

关键词： biotic and abiotic stresses feedback kinases protein turnover receptor subcellular localization

S-acylation of YKT61 modulates its unconventional participation in the formation of SNARE complexes in Arabidopsis

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Journal of Genetics and Genomics 2024年第10期51卷 1079-1088页

作者： Ting Ma Jun-Ru Tan jin-yu lu Sha Li Yan Zhang College of Life Sciences Shandong Agricultural UniversityTaianShandong 271018China Frontiers Science Center for Cell Responses College of Life SciencesNankai UniversityTianjin 300071China

Hetero-tetrameric soluble N-ethylmaleimide-sensitive factor attachment protein receptors(SNAREs)complexes are critical for vesicle-target membrane fusion within the endomembrane system of eukaryotic *** assembly involves four different SNARE motifs,Qa,Qb,Qc,and R,providedby three orfour SNARE ***6 is an atypical R-SNARE that lacks a transmembrane domain and is involved in multiple vesicle-target membrane *** YKT6 is evolutionarily conserved and essential,its function and regulation in different phyla seem *** YKT61,the yeast and metazoan YKT6 homologue,is essential for gametophytic development,plays a critical role in sporophytic cells,and me-diates multiple vesicle-target membrane ***,its molecular regulation is *** report here that YKT61 is *** its S-acylation by a C195S mutation dissociates YKT61 from endomembrane structures and causes its functional *** interacting with various SNARE pro-teins,YKT61functions not as a canonical R-SNAREbut coordinates with otherR-SNAREs to participate in theformationof ***-specific molecular regulation of YKT6 may be evolvedto allow more efficient SNARE assembly in different eukaryotic cells.

关键词： Longin domain S-acylation Vesicle trafficking R-SNARE Arabidopsis thaliana

Paraplegia from spinal intramedullary tuberculosis:A case report

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World Journal of Clinical Cases 2020年第24期8卷 6353-6357页

作者： Li-Mei Qu Di Wu Liang Guo jin-lu yu Department of Pathology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Neurosurgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND Tuberculosis (TB) mostly attacks the lungs, and extrapulmonary TB involving thecentral nervous system is uncommon;among these cases, spinal intramedullaryTB is even more rare. The clinical manifestations of spinal intramedullary TB aresimilar to those of intramedullary spinal cord tumors. Therefore, it is necessary tomake a careful differential diagnosis of spinal intramedullary lesions to achievethe appropriate treatment and favorable prognosis. We report a rare case of ayoung male patient with paraplegia due to spinal intramedullary TB, which isuncommon and *** SUMMARY A 23-year-old male presented with fever accompanied by nausea and vomitinglasting for 2 mo and was then diagnosed with tubercular meningitis. After anti-TBtreatment, his symptoms were significantly improved. However, 2 mo after thediagnosis of tubercular meningitis, the patient felt numbness below the costal archlevel, which lasted for 1 wk, and he paid no attention to this symptom. Whatfollowed was paraplegia and urine/fecal incontinence. Magnetic resonanceimaging of the thoracic spine showed a ring-enhanced intramedullary cord lesionat T8-T9. Lesion exploration showed enlargement of the spinal cord at T8-T9, andthe lesion could be observed by incision. The lesion was adhered to the peripheraltissue and was grayish-white and tough with a poor blood supply and a diameterof approximately 0.8 cm. The lesion was resected completely. The results ofpathological examination by both hematoxylin-eosin staining and acid-fast bacillistaining confirmed TB, accompanied by acute and chronic suppurativeinflammation and granulation tissue formation. The patient was instructed tocontinue anti-TB treatment after the operation, but he did not follow the medicaladvice. Follow-up continued for ten years, the patient had persistent paraplegia,the numbness disappeared and urine/fecal sensation *** Although TB is a kind of benign disease, some cases progress rapidly. Moreover,spina

关键词： Tuberculosis Intramedullary Extrapulmonary Central nervous system Paraplegia Case report

Cerebral infarct secondary to traumatic internal carotid artery dissection

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World Journal of Clinical Cases 2020年第20期8卷 4773-4784页

作者： Guang-Ming Wang Hang Xue Zhen-Jie Guo jin-lu yu Department of Neurosurgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND Traumatic internal carotid artery dissection(TICAD)is rare and can result in severe neurological disability and even *** consensus regarding its diagnostic screening and management has been *** To investigate the clinical presentation,imaging features,diagnostic workup,and treatment of *** In this retrospective case series,emergency admissions for TICAD due to closed head injury were *** demographic,clinical,and radiographic data were retrieved from patient charts and the picture archiving and communication *** Six patients(five males and one female,age range of 43-62 years,mean age of 52.67 years)presented with *** accidents(4/6)were the most frequent cause of *** clinical presentation was always related to brain *** examination revealed dissection of the affected artery and corresponding brain *** the patients were definitively diagnosed with *** patient was treated conservatively,one patient underwent anticoagulant therapy,two patients were given both antiplatelet and anticoagulant drugs,and two patients underwent decompressive *** patient fully recovered,while three patients were disabled at *** patients died of refractory brain *** TICAD can cause catastrophic outcomes and even refractory brain *** and efficient diagnosis of TICAD is essential for initiating appropriate *** treatment of TICAD is challenging and variable and is based on clinician discretion on a case-by-case basis.

关键词： Internal carotid artery dissection Brain infarction Treatment Prognosis

Ignition characteristics of pre-combustion plasma jet igniter

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Chinese Physics B 2019年第11期28卷 227-237页

作者： Si-Bo Wang jin-lu yu jing-Feng Y Guo-Hua Li Zhao Chen lu-yun Jiang Chen-Li Gu Air Force Engineering University Xi’an 710038China State Key Laboratory of Laser Interaction with Matter Northwest Institute of Nuclear TechnologyXi’an 710038China The University of Sheffield Western Bank SheffieldS102TNUK

At present, aero-engines face a major need to widen the ignition envelope. In order to provide a technical support to expand the high altitude ignition envelope of aero-engines, in this article we propose a novel ignition technology, i.e., "precombustion plasma jet ignition technology". In this paper, we also design a pre-combustion plasma jet igniter. Its discharge characteristics, jet characteristics, and ignition effects are studied. The results show that increasing the equivalent ratio of jet gas can enhance the discharge stability and increase the duty cycle. At the same time, it can reduce working power and energy consumption. The increase of equivalent ratio in jet gas can enhance the length and ignition area of plasma *** the process of ignition, the pre-combustion plasma jet igniter has obvious advantages, suchn as shortening the ignition delay time and enlarging the ignition boundary. When the airflow velocity is 39.11 m/s and the inlet air temperature is80℃, compared with the spark igniter and the air plasma jet igniter, the pre-combustion plasma jet igniter has an ignition boundary that is expanded by 319.8% and 55.7% respectively.

关键词： pre-combustion discharge stability ignition delay time ignition boundary

大数据时代个人信息“控制—利用”二元立法路径重构

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新疆大学学报（哲学社会科学版） 2024年第1期52卷 99-106页

作者：靳雨露清华大学法学院北京100084

大数据时代的个人信息立法应平衡个人信息控制保护与促进利用的关系。当前国内外个人信息立法的既有路径未协调好这一关系,出现知情同意机制失灵、个人信息出售机制乱象、匿名化制度遭遇技术壁垒的困局。破除既有路径困境的关键是从应... 详细信息

大数据时代的个人信息立法应平衡个人信息控制保护与促进利用的关系。当前国内外个人信息立法的既有路径未协调好这一关系,出现知情同意机制失灵、个人信息出售机制乱象、匿名化制度遭遇技术壁垒的困局。破除既有路径困境的关键是从应然目标、理论基础和规则重建三个方面,对个人信息“控制—利用”二元立法路径进行体系化重构。二元路径的目标是通过划清私人领域与公共领域的界限,以平衡个人信息控制保护与利用流通的关系;理论基础是承认个人信息的人格与财产双层、个人与公共的双重价值属性;通过构建个人信息直接识别、个人信息利用促进、利用规制和信息财产权属制度,重构个人信息控制保护与促进流通利用的规则体系。

关键词：大数据个人信息利用个人信息立法 “控制—利用”二元论

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论《民法典》隐私权:源起、冲突与重塑

青海民族大学学报（社会科学版） 2022年第1期48卷 89-97页

作者：靳雨露北京师范大学北京100875

隐私权概念可追溯至1890年沃伦与布兰代斯的《隐私权》一文。然而,该开创性的“隐私权”受当时特定历史、文化与制度背景的限制,存在法理上的悖论。我国《民法典》法律移植的隐私权概念受历史起源影响,一方面,不符合具体人格权的本源要... 详细信息

隐私权概念可追溯至1890年沃伦与布兰代斯的《隐私权》一文。然而,该开创性的“隐私权”受当时特定历史、文化与制度背景的限制,存在法理上的悖论。我国《民法典》法律移植的隐私权概念受历史起源影响,一方面,不符合具体人格权的本源要求;另一方面,司法实践中隐私权与个人信息保护规则的适用争议频出。要解决上述冲突,应明确隐私的本质属性和隐私界定的主观与客观标准,进而重新解读广义与狭义隐私权的内容,区分隐私权与个人信息保护规则的界限,使隐私权在司法实践中发挥应有的作用。

关键词：民法典隐私隐私权个人信息保护

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑yuan yu jing Wu Guang Yin Fan‑Zhen Jiao Zhong‑Zhen yu jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

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杆系结构可动性判定准则

工程力学 2006年第11期23卷 70-75,84页

作者：罗尧治陆金钰浙江大学空间结构研究中心杭州310027

基于矩阵的奇异值分解法,提出了杆系结构在考虑荷载作用下的可动性判定方法,包括含机构的杆系结构可动性判定和瞬变结构的判定。通过分析结构的平衡矩阵,计算自应力模态、机构位移模态,归纳出了荷载态下杆系结构可动性判定公式。结果显... 详细信息

基于矩阵的奇异值分解法,提出了杆系结构在考虑荷载作用下的可动性判定方法,包括含机构的杆系结构可动性判定和瞬变结构的判定。通过分析结构的平衡矩阵,计算自应力模态、机构位移模态,归纳出了荷载态下杆系结构可动性判定公式。结果显示若机构位移模态与荷载向量正交,则几何意义上的机构可演变为可以承受外界扰动、相对稳定的结构。另外对瞬变结构给出瞬变判定公式,弥补了体系分类的空缺。最后辅以算例验证,给出结论,系统列出细化后的结构体系分类表。

关键词：杆系结构瞬变结构可动性判定几何稳定性平衡矩阵奇异值分解法