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Chinese Chemical Letters 2016年第9期27卷 1537-1540页

作者： Jian Zhang jin-long wu Laboratary of Asymmetry Catalysis and synthesis Department of Chemistry Zhejiang University Hangzhou 310027 China

To study the intramolecular Diels-Alder cycloadditon of 2H-chromen-2-one as a diene, a series of chiral N-allyl-N-benzylamides that contain a 2H-chrornen-2-one moiety were designed for the synthesis of benzo[f]isoindol-1-ones via an intrarnolecular Diels-Alder and a subsequent retro-Diels-Alder cycloaddition with the expulsion of CO2. Both the yield （80%-89%） and absolute stereocontrol of the tandem reaction were high when an electron-withdrawing group was attached to the dienophile. The double bond in the styrene substructure remained in the products could be further derivatized by dihydroxylation.

关键词： 2H-Chromen-2-one Intramolecular Diels-Alder Retro-Diels-Alder Benzo[J]isoindol-1 -one Dihydroxylation

Arylation of Allyl, Cinnamyl and Propargyl Bromide with Triarylbismuth Catalyed by Pd(0)

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Chinese Chemical Letters 1997年第9期8卷 759-762页

作者： Xian HUANG jin long wu(Department of Chemistry, Hangzhou University Hangzhou, 310028) Department of Chemistry Hangzhou University Hangzhou 310028 China

Allyl and cinnamyl and propargyl bromide reacted under mild conditions with triarylbismuth under catalysis by Pd(O) to give 3-arylpropenes, 1, 3-diarylpropenes and arylpropadienes in modest to excellent yields.

关键词： Cinnamyl and Propargyl Bromide with Triarylbismuth Catalyed by Pd Ph Arylation of Allyl

A Novel Photoproduct of 2-Methoxycytosine in Phosphate Solution Under Far UV Irradiation

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Chinese Chemical Letters 1999年第8期10卷 623-624页

作者： Feng LIN jin long wu Xiao Wei FAN (Department of Chemistry, Zhejiang University. Hangzhou 310028) Department of Chemistry Zhejiang University Hangzhou 310028 China

Under the irradiation of medium pressure mercury lamp (MPML) the photolysis of 2-methoxycytosine (MAP) in phosphate solution leads to the production of a novel compound C5H8N3O5P. The composition and structure of the ... 详细信息

关键词： UV photolysis 2-methoxycytosine phosphate

A Facile and Highly Stereosclective Reductive Dcbromination of AnhydrO-6- (R)-Hydroxyethyl- 6-Bromopenicillin

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Chinese Chemical Letters 2000年第5期11卷 385-386页

作者： Bing ZHENG jin long wu Shao Jun XU Jian Feng SHI Yao Zu CHEN (Department of Chemistry, Zhejiang University, Hangzhou 310027 National Laboratory of Applied Organic Chemistry.Lanzhou 730000) Department of Chemistry Zhejiang University Hangzhou 310027 China Natl. Lab. of Appl. Organ. Chemistry Lanzhou 730000 China

Reductive debromination of anhydro-6-(R)-hydroxycthyl-6-(R) 7 by zinc in ammonium acetate gave 9 in 81% yield with high stcreosclectivity of 6-(α):6-(β)= 13: 1

关键词： Reductive debromination. stereoselcctivity. anhydro-6-(R)-hydroxyethyl-6-bromo- penicillin.

Life-threatening delayed mediastinal and subcutaneous emphysema after general anesthesia in a rheumatoid arthritis patient: a case report

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Clinical Research Communications 2023年第3期6卷 30-32页

作者： Ke-Qiang He jin-long wu Bin Hu Ji Yuan Chao-Liang Tang Department of Anesthesiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China

Background:Delayed mediastinal emphysema with subcutaneous emphysema after extubation is rarely reported in current *** treatment is considered effective for *** presentation:We report a case of a 56-year-old female with longstanding rheumatoid arthritis under corticosteroid therapy who developed mediastinal emphysema with subcutaneous emphysema 2 days after recovering from general anesthesia for orthopedic surgery treating a femoral neck *** patient received aggressive subcutaneous decompression and symptomatic ***:The patient’s condition improved after *** on computed tomography scan results,we hypothesize that the longstanding rheumatoid arthritis may have resulted in fragile lung *** postoperative coughing likely caused rupture of small airways,leading to mediastinal ***:It is crucial to preoperatively assess the risk of airway injury in high-risk patients with longstanding rheumatoid *** postoperative mediastinal emphysema should be carefully evaluated and managed aggressively to avoid exacerbation or life-threatening *** research is warranted to elucidate the pathology and guide perioperative management in these patients.

关键词： anesthesia mediastinal emphysema subcutaneous emphysema rheumatoid arthritis orthopedic surgery postoperative cough

Occult cervical lymph node metastases in 100 consecutive patients with cNO tongue cancer

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Chinese Medical Journal 2008年第19期121卷 1871-1874页

作者： jin wu-long YE Wei-min ZHENG Jia-wei ZHOU Liang ZHU Han-guang ZHANG Zhi-yuan TIAN Jie Department of Head and Neck Surgery Ear Nose and Throat Hospital School of Medicine Fudan University Shanghai 200031 China Department of Oral and Maxillofacial Surgery College of Stomatology Shanghai Ninth People's Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200011 China

Background Squamous cell carcinoma （SCC） of the tongue maxillofacial region. To provide clinical evidence for selective analyzing the characteristics and correlation of factors of occult with SCC of the tongue. is one of the most common cancers in the oral and neck dissection in management of cN0 patients by cervical lymph node metastases （OCLNM） in patients Methods From 2002 to 2006, 100 consecutive patients with SCC of the tongue were reviewed by analyzing the characteristics of OCLNM, diameter of the tumor, T classifications, depth of invasion, forms of growth, pathological grade and degree of differentiation. Results The rate of OCLNM in 100 patients with SCC of the tongue was 22%. The most common region with OCLNM was level Ⅱ in the ipsilateral neck, followed by levels Ⅰ and Ⅲ. There were 51.61% （16/31） of OCLNM in level Ⅱ and 87.10% （27/31） of OCLNM in levels Ⅰ-Ⅲ. There was no significant correlation between the diameter of tumor and OCLNM （P 〉0.05）. OCLNM was statistically significantly correlated with the depth of invasion, forms of growth, pathological grade and degree of differentiation （P 〈0.05）. The rate of occult metastases increased with the increased pathological grade, the decreased degree of differentiation and the increased depth of invasion. Conclusions The most common regions with OCLNM in cN0 patients with SCC of the tongue were levels Ⅰ-Ⅲ in the ipsilateral neck. Supraomohyoid neck dissection should be the elective treatment to the neck in patients with cN0 SCC of the tongue by consideration of the clinical and pathological factors for the depth of invasion, forms of growth, pathological grade, and degree of differentiation.

关键词： squamous cell carcinoma tongue cancer occult cervical lymph node metastases neck dissection pathology

口腔颌面部恶性肿瘤患者营养风险评估及相关因素分析

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上海口腔医学 2017年第6期26卷 637-640页

作者：刘莹金武龙内蒙古医科大学附属医院麻醉科内蒙古呼和浩特010050 内蒙古医科大学附属医院口腔颌面外科内蒙古呼和浩特010050

目的 :评估口腔颌面部恶性肿瘤患者潜在的营养风险,分析其相关因素,探讨营养风险的治疗途径。方法 :随机抽取88例口腔颌面部恶性肿瘤患者,记录其年龄、身高、体重、临床分期、血红蛋白、白蛋白、前白蛋白,目前治疗状况,计算患者的体重指... 详细信息

目的 :评估口腔颌面部恶性肿瘤患者潜在的营养风险,分析其相关因素,探讨营养风险的治疗途径。方法 :随机抽取88例口腔颌面部恶性肿瘤患者,记录其年龄、身高、体重、临床分期、血红蛋白、白蛋白、前白蛋白,目前治疗状况,计算患者的体重指数(BMI)。根据营养风险筛查表(NRS2002)计算其评分。采用SPSS 17.0软件包对计数资料行χ2检验。结果:88例口腔颌面部恶性肿瘤患者中,营养不足者(BMI<18.5 kg/m2)18例,占20.45%;有营养风险者(NRS2000评分≥3分)49例,占55.68%。结论:口腔颌面部恶性肿瘤患者营养风险发生率高,年龄越大,营养风险越高,贫血、白蛋白及前白蛋白水平降低会增加营养风险的发生率。

关键词：口腔颌面部肿瘤营养风险营养支持

改良式情景模拟教学模式用于牙体牙髓病学临床前期教学的评价

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上海口腔医学 2018年第1期27卷 110-112页

作者：格根塔娜金武龙刘双凤内蒙古医科大学附属医院口腔科内蒙古呼和浩特010050 内蒙古医科大学内蒙古呼和浩特010110

目的 :评价改良式情景模拟教学在牙体牙髓病学临床教学中的应用效果。方法 :将40名学生随机分为实验组和对照组,每组20名。实验组应用改良式情景模拟教学法,对照组应用传统教学法,采用SPSS 18.0软件包对教学效果进行评价。结果:实验组... 详细信息

目的 :评价改良式情景模拟教学在牙体牙髓病学临床教学中的应用效果。方法 :将40名学生随机分为实验组和对照组,每组20名。实验组应用改良式情景模拟教学法,对照组应用传统教学法,采用SPSS 18.0软件包对教学效果进行评价。结果:实验组学生在采集病史、书写病历、临床操作的分数均高于对照组,差异具有显著性(P<0.05)。结论:改良式情景模拟教学应用于牙体牙髓病学临床教学,其教学效果优于传统教学法,能使学生更好地掌握临床医疗要领并且能切身体会患者的感受,帮助学生提高学习的主观能动性。

关键词：改良式情景模拟教学牙体牙髓病学教学改革

Overproduction of OsRACK1A,an effector-targeted scaffold protein promoting OsRBOHB-mediated ROS production,confers rice floral resistance to false smut disease without yield penalty

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Molecular Plant 2022年第11期15卷 1790-1806页

作者： Guo-Bang Li Jia-Xue He jin-long wu He Wang Xin Zhang Jie Liu Xiao-Hong Hu Yong Zhu Shuai Shen Yi-Fei Bai Zong-Lin Yao Xin-Xian Liu jing-Hao Zhao De-Qiang Li Yan Li Fu Huang Yan-Yan Huang Zhi-Xue Zhao Ji-Wei Zhang Shi-Xin Zhou Yun-Peng Ji Mei Pu Peng Qin Shigui Li Xuewei Chen jing Wang Min He Weitao Li Xian-Jun wu Zheng-Jun Xu Wen-Ming Wang jing Fan State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Rice Research Institute Sichuan Agricultural UniversityChengdu 611130China

Grain formation is fundamental for crop yield but is vulnerable to abiotic and biotic *** grain production is threatened by the false smut fungus Ustilaginoidea virens,which specifically infects rice floral organs,disrupting fertilization and seed ***,little is known about the molecular mechanisms of the ***-rice interaction and the genetic basis of floral ***,we report that *** secretes a cytoplasmic effector,UvCBP1,to facilitate infection of rice ***,UvCBP1 interacts with the rice scaffold protein OsRACK1A and competes its interaction with the reduced nicotinamide adenine dinucleotide phosphate oxidase OsRBOHB,leading to inhibition of reactive oxygen species(ROS)*** the analysis of natural variation revealed no OsRACK1A variants that could avoid being targeted by UvCBP1,expression levels of OsRACK1A are correlated with field resistance against *** in rice *** of OsRACK1A restores the OsRACK1A-OsRBOHB association and promotes OsRBOHB phosphorylation to enhance ROS production,conferring rice floral resistance to *** without yield *** together,our findings reveal a new pathogenic mechanism mediated by an essential effector from a flower-specific pathogen and provide a valuable genetic resource for balancing disease resistance and crop yield.

关键词： rice flower false smut fungal effector scaffold protein reactive oxygen species disease resistance

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高压直流巡检机器人的磁力驱动方法

浙江大学学报（工学版） 2016年第10期50卷 1937-1945,1986页

作者：徐显金吴龙辉杨小俊汤亮杨永峰湖北工业大学机械工程学院湖北武汉430068

针对架空高压输电线路轮臂式巡检机器人易打滑问题,提出基于高压直流磁场的磁力驱动方法.利用载流线圈在高压直流磁场中受到的安培力作为牵引机器人移动的驱动力,取代以电机驱动的轮轨式移动方式,从而彻底消除打滑问题.根据高压直流输... 详细信息

针对架空高压输电线路轮臂式巡检机器人易打滑问题,提出基于高压直流磁场的磁力驱动方法.利用载流线圈在高压直流磁场中受到的安培力作为牵引机器人移动的驱动力,取代以电机驱动的轮轨式移动方式,从而彻底消除打滑问题.根据高压直流输电线路周围的磁场特性和对机器人驱动力的要求,建立实现磁力驱动力的物理模型,分析磁力驱动力与物理模型尺寸及线圈匝数之间的关系,提出利用磁场力来平衡横风力矩的方法.利用COMSOL软件对磁力驱动模型进行仿真,将磁力驱动力的仿真结果与理论计算值进行比较分析.结果表明,提出的磁力驱动方法理论上是正确的.依据提出的磁力驱动模型建立磁力驱动装置并进行实验,实验结果表明,提出的磁力驱动方法在技术上是可行的.

关键词：高压直流(HVDC) 巡检机器人高压直流磁场安培力磁力驱动