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黑龙江交通科技 2024年第7期47卷 160-163,168页

作者：金尧杨猛王海涛王雪梅黑龙江省交通运输信息和科学研究中心黑龙江哈尔滨150080 中诚安美建筑科技有限公司黑龙江哈尔滨150080

针对高速公路养护管理中决策支持数据不足问题,利用高速公路收费系统收费历史累积数据,采用大数据分析处理技术,研究了高速公路养护专题数据挖掘系统、流程和方法,列举了若干养护管理方面的隐性知识发现结果,并给出了货车轴型分布规律... 详细信息

针对高速公路养护管理中决策支持数据不足问题,利用高速公路收费系统收费历史累积数据,采用大数据分析处理技术,研究了高速公路养护专题数据挖掘系统、流程和方法,列举了若干养护管理方面的隐性知识发现结果,并给出了货车轴型分布规律和轴载荷分布模型。

关键词：高速公路收费数据挖掘公路养护

Investigation on microscopic invasion characteristics and retention mechanism of fracturing fluid in fractured porous media

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Petroleum Science 2022年第4期19卷 1745-1756页

作者： Qi-An Da Chuan-jin yao Xue Zhang Xiao-Pu Wang Xiao-Huan Qu Guang-Lun Lei Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580ShandongPeople's Republicof China School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongPeople's Republic of China Shandong Key Laboratory of Oilfield Chemistry China University of Petroleum(East China)Qingdao266580ShandongPeople's Republic of China

Reservoir damage caused by guar gum fracturing fluid and slick water seriously affects the subsequent oil and gas production. However, the invasion characteristics and retention mechanisms of fracturing fluids in the fracture-matrix zone are still unclear. In this work, a microscopic model reflecting the characteristics of the fracture-matrix zone was designed. Based on the microfluidic experimental method, the process of fracturing fluid invasion, flowback and retention in the fracture-matrix zone was investigated visually and characterized quantitatively. The factors and mechanisms affecting fracturing fluid retention in the fracture-matrix zone were analyzed and clarified. The results indicated that in the invasion process, the frontal swept range of slick water was larger than that of the guar gum fracturing fluid, and the oil displacement efficiency and damage rate were lower than those of the guar gum fracturing fluid under the same invasion pressure. With the increase in invasion pressure, the damage rate of slick water increased from 61.09% to 82.77%, and that of the guar gum fracturing fluid decreased from 93.45% to83.36%. Before subsequent oil production, the invaded fracturing fluid was mainly concentrated in the medium-high permeability area of the fracture-matrix zone. The main resistance of slick water was capillary force, while that of the guar fracturing fluid was mainly viscous resistance. The fracturing fluid retention was most serious in the low permeability region and the region near the end of the *** experimental and numerical simulation results showed that increasing the production pressure difference could improve the velocity field distribution of the fracture-matrix zone, increase the flowback swept range and finally reduce the retention rate of the fracture fluid. The retention mechanisms of slick water in the fracture-matrix zone include emulsion retention and flow field retention, while those of the guar gum fracturing fluid inc

关键词： Microfluidic experiment Reservoir damage Fracturing fluid Fracture-matrix zone Retention mechanism

H_(2)O_(2) actuated molybdenum oxide nanodots:Multi-enzyme-like activities,leverage of Fenton reaction,and dual-mode sensitive detection of alendronate sodium

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Nano Research 2023年第10期16卷 12106-12115页

作者： Siqi Wang yao jin Wenhui Ai Xiufeng Wang Zhiqing Zhang Ting Zhou Guodong Zhang Fang Wang Department of Chemistry College of Chemistry and Chemical EngineeringChina University of Petroleum(East China)Qingdao 266580China

Unexpected benefits to the catalytic performance of materials often originate from the presence of surface ***,novel Dpenicillamine modified molybdenum oxide nanodots,with abundant oxygen vacancy defects,were fabrication by a mild,simple,and cost-effective ***–visible(UV–Vis)absorption spectra analysis showed that the nanodots had peroxidaselike and catalase-like *** reactive oxygen species were probed by electronic paramagnetic resonance technique and spectroscopic methods,demonstrating that the nanodots also had oxidase-like ***,the peroxidase-like activity of nanodots was synergistically enhanced in the presence of ferrous ions or ferric ***,less than nanomolar levels of ferrous ions were required to display this phenomenon,meaning Fenton reagent acted as *** on this,a sensitive colorimetric and fluorescent dual-mode sensor for alendronate sodium was *** linear ranges for colorimetric and fluorescence analysis were 0.2–2.5 and 0.2–2.0μM,with detection limits of 31.21 and 71.84 nM,*** method has a simple large-scale material preparation process with higher sensitivity and shorter reaction time,which can inspire and enlighten the design of nanozyme sensors.

关键词： nanozyme molybdenum oxide Fenton reaction alendronate sodium multi-enzyme-like activities

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秸秆发电厂燃料收集半径与装机规模

电站系统工程 2024年第4期40卷 33-34页

作者：闫耀进陈新浩孙汉明中国电力工程顾问集团东北电力设计院有限公司中国机械设备工程股份有限公司哈尔滨电站设备成套设计研究所有限公司

为了缓解当前能源使用紧张的现况,减轻矿物燃料能源对生态环境带来的破坏影响,不少地区开始建设秸秆发电厂,通过秸秆燃烧进行发电,以秸秆代替矿物燃料能源。基于此,为了确保秸秆发电厂燃料发电的经济效益,将以此为中心简述如何在合适的... 详细信息

为了缓解当前能源使用紧张的现况,减轻矿物燃料能源对生态环境带来的破坏影响,不少地区开始建设秸秆发电厂,通过秸秆燃烧进行发电,以秸秆代替矿物燃料能源。基于此,为了确保秸秆发电厂燃料发电的经济效益,将以此为中心简述如何在合适的范围内确定发电厂燃料收集半径,理清秸秆发电厂燃料收集半径同装机规模之间的关系,保障秸秆燃料发电的稳定性。

关键词：秸秆发电厂燃料收集半径装机规模

The role and advantage of traditional Chinese medicine in the prevention and treatment of COVID-19

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结合医学学报:英文版 2023年第5期21卷 407-412页

作者： Ming Huang yao-yuan Liu Ke Xiong Feng-wen Yang Xin-yao jin Zhao-qi Wang Jun-hua Zhang Bo-li Zhang State Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Cardiology the First Teaching Hospital of Tianjin University of Traditional Chinese MedicineNational Clinical Research Center for Chinese Medicine Acupuncture and MoxibustionTianjin 300193China State Drug Administration Key Laboratory of Evidence-based Evaluation of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 301600China

The global coronavirus disease 2019(COVID-19)pandemic has had a massive impact on global social and economic development and human *** combining traditional Chinese medicine(TCM)with modern medicine,the Chinese government has protected public health by supporting all phases of COVID-19 prevention and treatment,including community prevention,clinical treatment,control of disease progression,and promotion of *** medicine focuses on viruses,while TCM focuses on differential diagnosis of patterns associated with viral infection of the body and recommends the use of TCM decoctions for differential *** differential diagnosis and treatment approach,with its profoundly empirical nature and holistic view,endows TCM with an accessibility advantage and high application value for dealing with ***,we summarize the advantage of and evidence for TCM use in COVID-19 prevention and treatment to draw attention to the scientific value and accessibility advantage of TCM and to promote the use of TCM in response to public health emergencies.

关键词： COVID-19 Traditional Chinese medicine Prevention and control Therapeutics

THR mRNA、ALCAT1在甲亢性心脏病中的协同诊断作用

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检验医学 2024年第1期39卷 60-67页

作者：张晓玲金瑶李素芳彭海英张家口市妇幼保健院内一科河北张家口075001

目的探讨甲状腺激素受体(THR)mRNA、心磷脂酰基转移酶1(ALCAT1)在甲亢性心脏病中的临床意义。方法选取2020年2月—2022年3月张家口市妇幼保健院甲亢性心脏病患者69例(甲亢性心脏病组)、单纯甲状腺功能亢进患者69例(单纯甲亢组)、非甲亢... 详细信息

目的探讨甲状腺激素受体(THR)mRNA、心磷脂酰基转移酶1(ALCAT1)在甲亢性心脏病中的临床意义。方法选取2020年2月—2022年3月张家口市妇幼保健院甲亢性心脏病患者69例(甲亢性心脏病组)、单纯甲状腺功能亢进患者69例(单纯甲亢组)、非甲亢性心脏病患者69例(非甲亢性心脏病组)和健康体检者69名(正常对照组)。收集所有研究对象的一般资料和实验室检测结果,并检测THRα1 mRNA、THRβ1 mRNA和ALCAT1。采用Logistic回归分析评估甲亢性心脏病发生的危险因素。采用相对超危险度比(RERI)、归因比(AP)和交互作用指数(SI)分析THR mRNA、ALCAT1在甲亢性心脏病发生中的交互作用。采用受试者工作特征(ROC)曲线评价THR mRNA、ALCAT1诊断甲亢性心脏病的效能。结果甲亢性心脏病组THRβ1 mRNA相对表达量和ALCAT1水平高于单纯甲亢组(P<0.001),THRα1 mRNA、THRβ1 mRNA相对表达量和ALCAT1水平高于非甲亢性心脏病组、正常对照组(P<0.001)。单纯甲亢组THRα1 mRNA、THRβ1 mRNA相对表达量和ALCAT1水平高于非甲亢性心脏病组、正常对照组(P<0.05),非甲亢性心脏病组THRα1 mRNA、THRβ1 mRNA相对表达量和ALCAT1水平高于正常对照组(P<0.05)。多因素Logistic回归分析结果显示,校正甲状腺功能亢进病程、游离三碘甲状腺原氨酸(FT_(3))、游离甲状腺素(FT_(4))、促甲状腺激素(TSH)、总三碘甲状腺原氨酸(TT_(3))、总甲状腺素(TT_(4))后,THRβ1 mRNA相对表达量和ALCAT1水平升高是甲亢性心脏病发生的危险因素[比值比(OR)值分别为3.185、3.712,95%可信区间(CI)分别为1.524~6.658、1.967~7.006,P<0.001]。THRβ1 mRNA与ALCAT1对甲亢性心脏病的发生存在正向交互作用,二者均高表达时甲亢性心脏病风险是二者均低表达时的9.000倍;二者同时高表达时甲亢性心脏病风险是其他未知因子(其OR=1)的3.148倍(RERI=3.148);协同效应是二者单独存在产生效应之和的1.855倍(SI=1.855);在二者共存的甲亢性心脏病风险中,有34.98%(AP=34.98%)由二者交互作用引起。ROC曲线分析结果显示,THRβ1 mRNA、ALCAT1单项检测和联合检测诊断甲亢性心脏病的曲线下面积(AUC)分别为0.798、0.726、0.872。结论THRβ1 mRNA、ALCAT1是甲亢性心脏病的独立危险因素,且对甲亢性心脏病的发生具有协同促进作用,二者联合检测可提升对甲亢性心脏病的诊断效能。

关键词：甲状腺激素受体心磷脂酰基转移酶1 甲亢性心脏病交互作用

Enhanced recovery of tight reservoirs after fracturing by natural gas huff-n-puff: Underlying mechanisms and influential factors

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Petroleum Science 2023年第6期20卷 3498-3515页

作者： Chuan-jin yao Ya-Qian Liu Bai-Shuo Liu Zheng-Dong Lei Jia Zhao Lei Li National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao 266580ShandongChina Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580ShandongChina School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Research Institute of Petroleum Exploration&Development PetroChinaBeijing100083China

Tight oil resources are abundant in the *** is very important to strengthen the research on the development theory and technology of tight oil reservoirs for ensuring national energy *** gas huff-n-puff can effectively improve the oil recovery of tight oil ***,the pore-scale oil production characteristics and the mechanisms of natural gas huff-n-puff in matrix-fracture cores are poorly *** influence degree of important factors on oil recovery is not clear and the interactions between factors are rarely *** this paper,the oil production characteristics and mechanisms of natural gas huff-n-puff in tight cores with different fracture lengths were quantitatively analyzed by combining nuclear magnetic resonance(NMR)with numerical simulation *** influencing factors and their interactions were evaluated by the response surface method(RSM).The results show that tight cores mainly consist of medium pores(0.1–1μm)and small pores(0.01–0.1μm).The fracture mainly increases the proportion of macro-pores(1–10μm)and medium *** the natural gas huff-n-puff process,crude oil from macro-pores(1–10μm)and medium pores is mainly developed,and the contribution percentage of crude oil in medium pores to oil recovery is the largest,up to 98.28%.The position of gas–oil contact(GOC)moves deeper as the number of huff-n-puff cycles *** contents of CH_(4) and CO_(2) in the oil phase remain at a high level within the GOC,while between the GOC and the component sweep front,the contents of CH_(4) and CO_(2) in the oil phase decrease with the increase in dimensionless *** gas component sweep volume is increasing with the increase in fracture ***,the injected natural gas mainly extracts C_(3)–C_(10) components from crude *** reduction law of crude oil viscosity is consistent with the migration laws of CH_(4) components along the *** with soaking time and gas diffusion coefficient,the inje

关键词： Natural gas huff-n-puff Matrix-fracture cores Nuclear magnetic resonance(NMR) Numerical simulation Response surface method(RSM)

Endometriosis of the lung: A case report and review of literature

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World Journal of Clinical Cases 2023年第18期11卷 4326-4333页

作者： jin yao Hong Zheng Hui Nie Cheng-Fang Li Wen Zhang jin-jing Wang Department of Pathology Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Lung endometriosis is an extremely rare gynecological *** literature reports suggest that the majority of patients will present with only generic symptoms,such as hemoptysis,pneumothorax,and hemopneumothorax,which often leads to *** date,there are 18 case reports of lung endometriosis that describe the clinical manifestation,imaging changes,treatment,and prognosis of the *** provide further insights into this rare disease,we present a new case report and a brief review of pulmonary *** SUMMARY We report here about a 19-year-old woman who was admitted to the hospital for repeated catamenial hemoptysis over a 3-mo *** tomography(CT)imaging during menstruation revealed patchy high-density shadows,approximately 0.5 cm3 in size,in the right middle lobe of the *** patient’s hemoptysis and changes in the CT scans resolved after *** right middle lobectomy,right lower lung repair,and closed thoracic drainage were *** histopathology confirmed lung *** was no recurrence of symptoms at the 6 mo *** We propose diagnosing lung endometriosis by thoroughly taking reproductive history,clinical details,imaging,and histopathology followed by treatment with surgical resection.

关键词： Lung endometriosis Immunophenotype Differential diagnosis Pathogenesis Case report

Optical coherence tomography angiography for macular microvessels in ischemic branch retinal vein occlusion treated with conbercept:predictive factors for the prognosis

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2049-2055页

作者： Li Tang Guang-Li Sun Yue Zhao Ting-Ting Yang jin yao Department of Ophthalmology the Affiliated Eye Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina

AIM:To evaluate the predicative factors of visual prognosis using optical coherence tomography angiography(OCTA)in ischemic branch retinal vein occlusion(BRVO)patients with macular edema(ME)after anti-vascular endothelial growth factor(VEGF)***:In this retrospective analysis,data from 60 patients(60 eyes)with a definite diagnosis of ischemic BRVO with ME by fundus fluorescein angiography(FFA)were *** eyes with ME according to spectral domain optical coherence tomography(SD-OCT)underwent intravitreal conbercept(IVC)and 3+pro re nata(PRN)*** injection times were *** weeks after injection,fundus laser photocoagulation was performed in the non-perfusion area of the *** patients were followed up once a month for *** bestcorrected visual acuity(BCVA),foveal avascular zone(FAZ),and A-circularity index(AI),at 6mo and the baseline were ***:All patients showed significant improvement in BCVA from 0.82±0.32 to 0.39±0.11 logMAR(P<0.001).The mean central macular thickness(CMT)significantly decreased from 476.22±163.54 to 298.66±109.23μ*** the FAZ area and AI at 6mo were significantly higher than those at the baseline:the FAZ area increased(0.38±0.02 vs 0.39±0.02 mm^(2),P<0.05);the AI increased(1.27±0.02 vs 1.31±0.01,P=0.000).The baseline BCVA showed a significantly positive correlation with the baseline FAZ area,FAZ perimeter(PERIM)and AI,final visual gain(FVG)and injection times,respectively(P<0.001).FVG showed a significantly negative correlation with the FAZ area,PERIM,AI and injection times,but a significantly positive correlation with vessel densities(VDs)300μm area around FAZ(FD-300;P<0.001).Injection times was positively correlated with the baseline FAZ area,and AI,but inversely correlated with the baseline FD-300(P<0.001).However macular ischemia was noted in 5 cases during ***:Using OCTA to observe macular ischemia and quantify parameters can better predict the final visual prognosis of p

关键词： optical coherence tomography angiography branch retinal vein occlusion macular edema foveal avascular zone conbercept

电力工程EPC总承包项目风险管理的优化措施

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电站系统工程 2024年第3期40卷 81-82页

作者：闫耀进王小萌张振宇中国电力工程顾问集团东北电力设计院有限公司中国机械设备工程股份有限公司哈尔滨电站设备成套设计研究所有限公司

EPC总承包项目模式作为快捷可靠的电力工程项目建设模式,成为当下电力建设的主流方式。由于电力工程EPC总承包项目模式实施过程中会存在些许不确定性,所以或多或少都会出现项目风险问题。对电力工程EPC总承包模式可能出现的风险进行简... 详细信息

EPC总承包项目模式作为快捷可靠的电力工程项目建设模式,成为当下电力建设的主流方式。由于电力工程EPC总承包项目模式实施过程中会存在些许不确定性,所以或多或少都会出现项目风险问题。对电力工程EPC总承包模式可能出现的风险进行简要分析,并提出相应的风险管理优化建议,以供电力工程项目风险管控参考。

关键词：电力工程 EPC总承包项目风险管理优化