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Identification of anti-cancer compounds from natural products

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Chinese Journal of Natural Medicines 2020年第7期18卷 481-482页

作者： LU jin-jian WANG Yi-Tao State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao 999078China

Natural products serve as abundant resources with diversity of chemical structures,which has been widely explored for the pharmacological researches and drug discovery[1,2].They are generally isolated from microorgani... 详细信息

关键词： cancer abundant compounds

A New Superlinearly Convergent SQP Algorithm for Nonlinear Minimax Problems

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Acta Mathematicae Applicatae Sinica 2007年第3期23卷 395-410页

作者： jin-bao jian Ran Quan Qing-jie Hu College of Mathematics and Information Science Guangxi University Nanning 530004 China College of Electrical Engineering Guangxi University Nanning 530004 Chin Department of Information Hunan Business College Changsha 410205 China

In this paper, the nonlinear minimax problems are discussed. By means of the Sequential Quadratic Programming （SQP）, a new descent algorithm for solving the problems is presented. At each iteration of the proposed algorithm, a main search direction is obtained by solving a Quadratic Programming （QP） which always has a solution. In order to avoid the Maratos effect, a correction direction is obtained by updating the main direction with a simple explicit formula. Under mild conditions without the strict complementarity, the global and superlinear convergence of the algorithm can be obtained. Finally, some numerical experiments are reported.

关键词： Minimax problems SQP algorithm global convergence superlinear convergence

A Feasible Point Method with Bundle Modification for Nonsmooth Convex Constrained Optimization

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Acta Mathematicae Applicatae Sinica 2018年第2期34卷 254-273页

作者： jin-bao jian Chun-ming TANG Lu SHI College of Mathematics and Information Science Guangxi University Nanning 530004 China College of Science Guangxi University of Nationalities Nanning 530007 China Xingjian College of Science and Liberal Arts Guangxi University Nanning 530005 China

In this paper, a bundle modification strategy is proposed for nonsmooth convex constrained min- imization problems. As a result, a new feasible point bundle method is presented by applying this strategy. Whenever the stability center is updated, some points in the bundle will be substituted by new ones which have lower objective values and/or constraint values, aiming at getting a better bundle. The method generates feasible serious iterates on which the objective function is monotonically decreasing. Global convergence of the algorithm is established, and some preliminary numerical results show that our method performs better than the standard feasible point bundle method.

关键词： nonsmooth optimization feasible point method bundle modification global convergence

A Bregman-style Partially Symmetric Alternating Direction Method of Multipliers for Nonconvex Multi-block Optimization

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Acta Mathematicae Applicatae Sinica 2023年第2期39卷 354-380页

作者： Peng-jie LIU jin-bao jian Guo-dong MA School of Mathematics China University of Mining and TechnologyXuzhou 221116China College of Mathematics and Physics Center for Applied Mathematics of GuangxiGuangxi Minzu UniversityNanning 530006China

The alternating direction method of multipliers(ADMM)is one of the most successful and powerful methods for separable minimization *** on the idea of symmetric ADMM in two-block optimization,we add an updating formula for the Lagrange multiplier without restricting its position for multiblock ***,combining with the Bregman distance,in this work,a Bregman-style partially symmetric ADMM is presented for nonconvex multi-block optimization with linear constraints,and the Lagrange multiplier is updated twice with different relaxation factors in the iteration *** the suitable conditions,the global convergence,strong convergence and convergence rate of the presented method are analyzed and ***,some preliminary numerical results are reported to support the correctness of the theoretical assertions,and these show that the presented method is numerically effective.

关键词： nonconvex optimization multi-block optimization alternating direction method with multipliers Kurdyka-Lojasiewicz property convergence rate

Simulation of municipal solid waste gasification for syngas production in fixed bed reactors

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第8期11卷 619-628页

作者： Chong CHEN Yu-qi jin jian-hua YAN Yong CHI State Key Laboratory of Clean Energy Utilization Zhejiang University Hangzhou 310027 China

This study proposes a model of syngas production from municipal solid waste (MSW) gasification with air in fixed bed reactors. The model (using Aspen plus simulator) is used to predict the results of MSW gasification and to provide some process fundamentals concerning syngas production from MSW gasification. The effects of gasification temperature, air equiva- lence ratio and moisture concentration on the composition of syngas, lower heating value (LHV) of syngas, heat conversion efficiency, and carbon conversion are discussed. The results indicate that higher temperature improves gasification, and higher air equivalence ratio increases the carbon conversion while decreasing syngas LHV. Heat conversion efficiency increases and reaches the maximum and then decreases with the increase of air equivalence ratio. Higher moisture concentration increases the carbon conversion and increases the heat conversion efficiency at lower ratios. Higher temperature and a lower equivalence ratio are favorable for obtaining a higher LHV of syngas at the same moisture concentration.

关键词： Municipal solid waste (MSW) Gasification Syngas Aspen plus Fixed bed

High performance metal oxide based sensing device using an electrode with a solid/liquid/air triphase interface

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Nano Research 2017年第9期10卷 2998-3004页

作者： Jun Zhang Xia Sheng jian jin Xinjian Feng Lei jiang College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China School of Chemistry and Environment Beihang University Beijing 100191 China

The wetting properties of an electrode surface are of significant importance to the performance of electrochemical devices because electron transfer occurs at the electrode/electrolyte interface. Described in this paper is a low-cost metal oxide electrocatalyst (CuO)-based high-performance sensing device using an enzyme electrode with a solid/liquid/air triphase interface in which the oxygen level is constant and sufficiently high. We apply the sensing device to detect glucose, a model test analyte, and demonstrate a linear dynamic range up to 50 mM, which is about 25 times higher than that obtained using a traditional enzyme electrode with a solid/liquid diphase interface. Moreover, we show that sensing devices based on a triphase assaying interface are insensitive to the significant oxygen level fluctuation in the analyte solution.

关键词： superhydrophobicity triphase interface metal oxide electrocatalyst sensing device

Application of a 3D-printed ”fistula stent” in plugging enteroatmospheric fistula with open abdomen: A case report

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World Journal of Gastroenterology 2019年第14期25卷 1775-1782页

作者： Zi-Yan Xu Hua-jian Ren jin-jian Huang Zong-An Li jian-An Ren Research Institute of General Surgery Jinling Hospital School of Medicine Nanjing University NARI School of Electrical and Automation Engineering Nanjing Normal University

BACKGROUND Open abdomen(OA) has been generally accepted for its magnificent superiority and effectiveness in patients with severe trauma, severe intra-abdominal infection, and abdominal compartment syndrome. In the meantime, OA calls for a mass of nursing and the subsequent enteroatomospheric fistula(EAF), which is one of the most common complications of OA therapy, remains a thorny *** SUMMARY Our team applied thermoplastic polyurethane as a befitting material for producing a 3 D-printed "fistula stent" in the management of an EAF patient,who was initially admitted to local hospital because of abdominal pain and distension and diagnosed with bowel obstruction. After a series of operations and OA therapy, the patient developed an *** Application of this novel "fistula stent" resulted in a drastic reduction in the amount of lost enteric effluent and greatly accelerated rehabilitation processes.

关键词： 3D printing Enteroatmospheric fistula Open abdomen Isolation technique Case report

A new radar stealth design excited by ^(210)Po and ^(242)Cm

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Nuclear Science and Techniques 2022年第6期33卷 45-53页

作者： jin-jian Yuan Gui-Ping Meng Min Gu Run-Sheng Huang School of Physics Nanjing UniversityNanjing 210093China

Open plasma stealth technology excited by radionuclides is known to have several problems:(1)owing to disturbance from airflow,the plasma distribution is unstable.(2)The plasma is highly dependent on the atmosphere;therefore,it is difficult to modulate in target stealth.(3)Concerns regarding radiation harassment prevent the application of this *** avoid these problems,an enclosed plasma stealth method is *** simulation on an infinite conducting plate,this method was found to effectively solve the above concerns,which may offer a new approach for the practical application of plasma stealth technology excited by radionuclides,especially for small-satellite stealth because of its lightweight and selfprovided plasma.

关键词： Radiation ionization αDecay particles Plasma film Radar stealth technology

Detection of social group instability among captive rhesus macaques using joint network modeling

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Current Zoology 2015年第1期61卷 70-84页

作者： Brianne A. BEISNER jian jin Hsieh FUSHING Brenda MCCOWAN Department of Population Health & Reproduction School of Veterinary Medicine UC Davis Davis CA 95616 USA California National Primate Research Center University of California Davis Davis CA 95616 USA Department of Statistics UC Davis Davis CA 95616 USA

Social stability in group-living animals is an emergent property which arises from the interaction amongst multiple behavioral networks. However, pinpointing when a social group is at risk of collapse is difficult. We used a joint network model- ing approach to examine the interdependencies between two behavioral networks, aggression and status signaling, from four sta- ble and three unstable groups of rhesus macaques in order to identify characteristic patterns of network interdependence in stable groups that are readily distinguishable from unstable groups. Our results showed that the most prominent source of aggres- sion-status network interdependence in stable social groups came from more frequent dyads than expected with opposite direc- tion status-aggression （i.e. A threatens B and B signals acceptance of subordinate status）. In contrast, unstable groups showed a decrease in opposite direction aggression-status dyads （but remained higher than expected） as well as more frequent than ex- pected dyads with bidirectional aggression. These results demonstrate that not only was the stable joint relationship between ag- gression and status networks readily distinguishable from unstable time points, social instability manifested in at least two differ- ent ways. In sum, our joint modeling approach may prove useful in quantifying and monitoring the complex social dynamics of any wild or captive social system, as all social systems are composed of multiple interconnected networks [Current Zoology 61 （1）： 70-84, 2015].

关键词： Nonhuman primates Network stability Social network analysis Dominance Aggression Status signaling