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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第9期14卷 793-799页

作者： jin gook kim Hong Lim kim Su jin kim Kyo-Sun PARK Department of Horticulture College of Agriculture and Life SciencesGyeongsang National University Institute of Agriculture and Life Sciences Gyeongsang National University Namhae Sub-Station National Institute of Horticultural and Herbal Science Fruit Research Division National Institute of Horticultural and Herbal Science

Blueberry fruits from 45 commercial cultivars (39 northern highbush and 6 half highbush blueberry) grown in Suwon,Korea were analyzed for fruit size,soluble solids content,titratable acidity,total anthocyanin content,total phenolic content,and antioxidant *** characteristics varied widely among the 45 blueberry *** weight ranged from 0.9 to 3.6 g,soluble solids content from 8.3 to 14.3 °Brix,and titratable acidity from 0.8% to 3.6%.Antioxidant activity ranged from 0.7 to 2.1 mg of quercetin equivalents per gram of fresh berries in different blueberry *** the 45 blueberry cultivars,high amounts of anthocyanins and polyphenols,and high antioxidant activity were observed in 'Elliott','Rubel','Rancocas',and 'Friendship'.

关键词： Northern highbush blueberry Half highbush blueberry Functional food Fruit quality

Environmental Sound Event Detection in Wireless Acoustic Sensor Networks for Home Telemonitoring

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China Communications 2017年第9期14卷 1-10页

作者： Hyoung-gook kim jin Young kim The Dept. of Electronics Convergence Engineering Kwangwoon University The Dept. of Electronics and Computer Engineering Chonnam National University

In this paper, we present an approach to improve the accuracy of environmental sound event detection in a wireless acoustic sensor network for home monitoring. Wireless acoustic sensor nodes can capture sounds in the home and simultaneously deliver them to a sink node for sound event detection. The proposed approach is mainly composed of three modules, including signal estimation, reliable sensor channel selection, and sound event detection. During signal estimation, lost packets are recovered to improve the signal quality. Next, reliable channels are selected using a multi-channel cross-correlation coefficient to improve the computational efficiency for distant sound event detection without sacrificing performance. Finally, the signals of the selected two channels are used for environmental sound event detection based on bidirectional gated recurrent neural networks using two-channel audio features. Experiments show that the proposed approach achieves superior performances compared to the baseline.

关键词： sound event detection wirelesssensor network gated recurrent neural net-work multichannel audio

Effect of ammonia gas etching on growth of vertically aligned carbon nanotubes/nanofibers

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Transactions of Nonferrous Metals Society of China 2011年第A01期21卷 130-134页

作者： Sang-gook kim Sooh-Yung kim Hyung-Woo LEE Department of Mechanical Engineering Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 USA National Core Research Center for Hybrid Materials Solution Pusan National University

The etching effect of ammonia （NH3） on the growth of vertically aligned nanotubes/nanofibers （CNTs） was investigated by direct-current plasma enhanced chemical vapor deposition （DC-PECVD）. NH3 gas etches Ni catalyst layer to form nanoscale islands while NH3 plasma etches the deposited amorphous carbon. Based on the etching effect of NH3 gas on Ni catalyst, the differences of growing bundles of CNTs and single strand CNTs were discussed; specifically, the amount of optimal NH3 gas etching is different between bundles of CNTs and single strand CNTs. In contrast to the CNT carpet growth, the single strand CNT growth requires shorter etching time （5 min） than large catalytic patterns （10 rain） since nano dots already form catalyst islands for CNT growth. Through removing the plasma pretreatment process, the damage from being exposed at high temperature substrate occurring during the plasma generation time is minimized. High resolution transmission electron microscopy （HTEM） shows fishbone structure of CNTs grown by PECVD.

关键词： carbon nanotube ammonia etching nickel catalyst plasma enhanced chemical vapor deposition (PECVD)

Buckled MEMS Beams for Energy Harvesting from Low Frequency Vibrations

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Research 2019年第1期2019卷 697-710页

作者： Ruize Xu Haluk Akay Sang-gook kim Massachusetts Institute of Technology Mechanical Engineering DepartmentCambridgeMA 02139USA

Vibration energy harvesters based on the resonance of the beam structure work efectively only when the operating frequency window of the beam resonance matches with the available vibration *** of the resonating MEMS structures can operate with low frequency,low amplitude,and unpredictable ambient vibrations since the resonant frequency goes up very high as the structure gets *** buckled beam energy harvester is therefore developed for lowering the operating frequency window below 100Hz for the frst time at the MEMS *** design does not rely on the resonance of the MEMS structure but operates with the large snapping motion of the beam at very low frequencies when input energy overcomes an energy threshold.A fully functional piezoelectric MEMS energy harvester is designed,monolithically fabricated,and *** electromechanical lumped parameter model is developed to analyze the nonlinear dynamics and to guide the design of the nonlinear oscillator based energy *** beam structure with residual stress induced buckling is achieved through the progressive residual stress control of the deposition processes along the fabrication *** profle of the released device shows bistable buckling of 200μm which matches well with the amount of buckling *** testing demonstrates the energy harvester operates with 50%bandwidth under 70Hz at 0.5g input,operating conditions that have not been demonstrated by MEMS vibration energy harvesters before.

关键词： buckling overcome steps

Increased susceptibility of ethanol-treated gastric mucosa to naproxen and its inhibition by DA-9601, an Artemisia asiatica extract

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World Journal of Gastroenterology 2005年第47期11卷 7450-7456页

作者： Tae Young Oh gook Jun Ahn Seul Min Choi Byoung Ok Ahn Won Bae kim Research Laboratories Dong-A Pharm. Co.Ltd.47-5SanggalKiheungYonginKyunggi449-905South Korea

AIM： To examine the effect of DA-9601, a new gastroprotective agent, on the vulnerability of ethanoltreated rat＇s stomach to naproxen （NAP）. METHODS： Male Sprague-Dawley rats were pretreated with 1 mL of 50% ethanol twice a day for 5 d and then NAP （50 mg/kg） was administered. DA-9601 was admin- istered 1 h before NAP. Four hours after NAP, the rats were killed to examine gross injury index （mm2）, histologic change and to determine mucosal levels of malondialdehyde （MDA）, prostaglandin E2 （PGE2）, glutathione （GSH） and myeloperoxidase （MPO）. RESULTS： Pretreatment of ethanol significantly increased NAP-induced gastric lesions, as well as an increase in NDA and MPO. On the contrary, mucosal PGE2 and GSH contents were decreased dramatically by ethanol pretreatment, which were aggravated by NAR DA-9601 significantly reduced NAP-induced gastric injury grossly and microscopically, regardless of pretreatment with ethanol. DA-9601 preserved, or rather, increased mucosal PGE2 and GSH in NAP-treated rats （P〈0.05）, with reduction in mucosal MDA and MPO levels. CONCLUSION： These results suggest that repeated alcohol consumption renders gastric mucosa more susceptible to NSAIDs though, at least in part, reduction of endogenous cytoprotectants including PGE2 and GSH, and increase in MPO activation, and that DA-9601, a new gastroprotectant, can reduce the increased vulnerability of ethanol consumers to NSAIDs-induced gastric damage via the mechanism in which PGE2 and GSH are involved.

关键词： DA-9601 Alcohol Naproxen Gastric damage Malondialdehyde Prostaglandin E2 Glutathione Myeloperoxidase NSAIDS

Mycobacterium ulcerans infection as a cause of chronic diarrhea in an AIDS patient: A case report

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World Journal of Gastroenterology 2008年第5期14卷 808-811页

作者： jin-gook Huh You-Sun kim Jong-Sung Lee Tae-Yeob Jeong Soo-Hyung Ryu Jung-Hwan Lee Jeong-Seop Moon Yun-Kyung Kang Myung-Shup Shim Myoung-Don Oh Department of Internal Medicine Inje University College of Medicine Seoul 100-032 South Korea Department of Pathology Inje University College of Medicine Seoul 100-032 South Korea Korean Institute of Tuberculosis Seoul South Korea Department of Internal Medicine Seoul National University College of Medicine Seoul South Korea

Chronic diarrhea is one of the most frequent gastro-intestinal manifestations in acquired immunodeficiency syndrome (AIDS). Protozoa and nontuberculous mycobacteria (NTM) are opportunistic pathogens that can easily infect these patients. Among the NTM, Mycobacterium avium complex (MAC) is the most frequently observed pathogen in HIV-infected patients. However, NTMs other than MAC have not been reported as a gastrointestinal pathogen as yet. We present a case of chronic diarrhea in an AIDS patient in whom Mycobacterium ulcerans and cryptosporidium co-infection is evidenced from colonic tissue.

关键词： Mycobacterium ulcerans Cryptosporidium HIV Chronic diarrhea

Molecular mechanisms of apoptosis induced by Scorpio water extract in human hepatoma HepG2 cells

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World Journal of Gastroenterology 2005年第7期11卷 943-947页

作者： Kang-Beom Kwon Eun-Kyung kim Jung-gook Lim Eun-Sil Jeong Byung-Cheul Shin Young-Se Jeon Kang-San kim Eun-A Seo Do-Gon Ryu Department of Physiology Department of Rehabilitation Medicine Department of Internal Medicine Department of Food and Nutrition

AIM: To clarify the mechanism underlying the anti-mutagenic and anti-cancer activities of Scorpio water extract (SWE). METHODS: Human hepatoma HepG2 cells were incubated with various concentrations of SWE. After 24-h incubation, cytotoxicity and apoptosis evaluations were determined by MTT and DNA fragmentation assay, respectively. After treatment with SWE, mitochondrial membrane potential (MMP) was determined by measuring the retention of the dye 3,3'-dihexyloxacarbocyanine (DiOC6(3)) and the protein expression including cytochrome C and poly-(ADPribose) polymerase (PARP) were measured by Western blotting. Caspase-3 and -9 enzyme activities were measured using specific fluorescence dyes such as Ac-DEVD-AFC and Ac-LEHD-AFC. RESULTS: We found that treatment with SWE induced apoptosis as confirmed by discontinuous DNA fragmentation in cultured human hepatoma HepG2 cells. Our investigation also showed that SWE-induced apoptosis of HepG2 cells were associated with intracellular events including disruption of MMP, increased translocation of cytochrome C from mitochondria to cytosol, activation of caspase-3, and PARP. Pre-treatment of N-acetyl-Asp-Glu-Val-Asp-CHO (Ac-DEVD-CHO), a caspase-3 specific inhibitor, or cyclosporin A (CsA), an inhibitor of MMP disruption, completely abolished SWE-induced DNA fragmentation. CONCLUSION: These results suggest that SWE possibly causes mitochondrial damage, leading to cytochrome C release into cytosol and activation of caspases resulting in PARP cleavage and execution of apoptotic cell death in HepG2 cells. These results further suggest that Scorpio may be a valuable agent of therapeutic intervention of human hepatomas.

关键词： Scorpio Human hepatoma HepG2 cell Apoptosis

Reliability Evaluation Methodologies of Fault Tolerant Techniques of Digital I&C Systems in Nuclear Power Plants

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Reliability Evaluation Methodologies of Fault Tolerant Techn...

韩国健康志愿者中氯吡格雷和伊曲康唑对依法韦仑代谢的影响及其与CYP2B6基因型的关系

International Symposium on Future I&C for Nuclear Power Plants Cognitive Systems Engineering in Process Control International Symposium on Symbiotic Nuclear Power Systems(ICI2011)

作者： kim Bo Gyung KANG Hyun gook LEE Seung Jun SEONG Poong Hyun Department of Nuclear and Quantum Engineering KAIST373-1Guseong-DongYuseong-GuDaejeonSouth Korea305-701 Integrated Safety Assessment Division Korea Atomic Energy Research Institute1045 Daedeok-daeroYuseongDaejeon305-353Korea Department of Nuclear Engineering Khalifa University of ScienceTechnology & ResearchAbu DhabiUAE

Since the reactor protection system was replaced from analog to digital,digital reactor protection system has 4 redundant channels and each channel has several *** is necessary for various fault tolerant techniques to improve availability and reliability due to using complex components in *** researches make an effort to effects of fault tolerant ***,the effects of fault tolerant techniques have not been properly considered *** consider the effects of fault tolerant techniques,we should consider how to apply overall fault detection coverage,fault recovery process,and fault tolerant techniques’ operation conditions.

关键词： Fault Tolerant Techniques Digital Plant Protection System Reliability Unavailability

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韩国健康志愿者中氯吡格雷和伊曲康唑对依法韦仑代谢的影响及其...