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Probing dark matter particles from evaporating primordial black holes via electron scattering in the CDEX-10 experiment

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Science China(Physics,Mechanics & Astronomy) 2024年第10期Mechanics & Astronomy) .卷 87-95页

作者： Zhenhua Zhang Litao Yang Qian Yue Kejun Kang Yuanjing Li Haipeng An Greeshma C. Jianping Chang Yunhua Chen Jianping Cheng Wenhan Dai Zhi Deng Changhao Fang Xinping Geng Hui Gong Qiuju Guo Tao Guo Xuyuan Guo Li He Shengming He Jinwei Hu Hanxiong Huang Tuchen Huang Lin Jiang S.Karmakar Haubin Li Hanyu Li Jianmin Li Jin Li Qianyun Li Renmingjie Li Xueqian Li Yulan Li Yifan Liang Bin Liao FongKay Lin ShinTed Lin Jiaxuan Liu Shukui Liu Yandong Liu Yu Liu Yuanyuan Liu Hao Ma Yucai Mao Qiyuan Nie Jinhua Ning Hui Pan Ningchun Qi Jie Ren Xichao Ruan Monoj Kumar Singh Tianxi Sun Changjian Tang Yang Tian Guangfu Wang Junzheng Wang Li Wang Qing Wang Yufeng Wang Yunxiang Wang Henry Tsz-King Wong Shiyong Wu Yucheng Wu Haoyang Xing Rui Xu Yin Xu Tao Xue Yulu Yan Nan Yi Chunxu Yu Haijun Yu Jianfeng Yue Ming Zeng Zhi Zeng Bingtao Zhang Fengshou Zhang Lei Zhang Zhenyu Zhang Jizhong Zhao Kangkang Zhao Minggang Zhao jifang zhou Zuying zhou Jingjun Zhu CDEX Collaboration Key Laboratory of Particle and Radiation Imaging (Ministry of Education) and Department of Engineering Physics Tsinghua University Department of Physics Tsinghua University Institute of Physics Academia Sinica NUCTECH Company YaLong River Hydropower Development Company College of Nuclear Science and Technology Beijing Normal University College of Physics Sichuan University School of Physics Peking University Department of Nuclear Physics China Institute of Atomic Energy Sino-French Institute of Nuclear and Technology Sun Yet-sen University School of Physics Nankai University Department of Physics Banaras Hindu University Department of Physics Beijing Normal University

Dark matter（DM） is a major constituent of the ***,no definite evidence of DM particles（denoted as “χ”） has been found in DM direct detection（DD） experiments to *** is a novel concept of detectingχfrom evaporating primordial black holes（PBHs）.We search forχemitted from PBHs by investigating their interaction with target *** examined PBH masses range from 1×1015to 7×1016g under the current limits of PBH abundance *** 205.4 kg·day data obtained from the CDEX-10 experiment conducted in the China Jinping Underground Laboratory,we exclude the χ-electron（χ-e） elastic-scattering cross section σχe～5×10-29cm2for χ with a mass ■ keV from our *** the higher radiation background but lower energy threshold（160 eV）,CDEX-10 fills a part of the gap in the previous *** (mχ,σχe) can be determined in the future,DD experiments are expected to impose strong constraints on fPBHfor large MPBHs.

关键词： CDEX primordial black hole light dark matter particle dark matter-electron scattering high purity germanium detector

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Practices on rockburst prevention and control in headrace tunnels of Jinping II hydropower station

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Journal of Rock Mechanics and Geotechnical Engineering 2012年第3期4卷 258-268页

作者： Jimin Wang Xionghui Zeng jifang zhou Ertan Hydropower Development Company Ltd. Chengdu 610051 China

Rockburst problems induced by high in-situ stresses were prominent during construction of the headrace tunnels of Jinping II hydropower station. The rockbursts occurred in various forms, and it is necessary to take pertinent measures for integrated prevention and control of rockbursts. In view of the rockburst characteristics during tunnel construction of Jinping II hydropower station, the engineering geological conditions were presented, and the features, mechanisms and forms of rockbursts observed during construction were analyzed in detail. A large number of scientific researches, experiments and applications were conducted. Multiple measures were adopted to prevent and control rockbursts, including the prediction and early warning measures, stress relief by blasting in advance, optimized blasting design and optimized tunnel support in the tunnel sections prone to strong rockbursts. The effectiveness of these prevention and control measures was evaluated. Experiences have been accumulated through a great number of helpful explorations and practices for rockburst prevention and control. A comprehensive rockburst prevention and control system has been gradually established.

关键词： long and deep tunnel rockburst prevention and control stress relief by blasting microseismic monitoring

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A gaseous time projection chamber with Micromegas readout for low-radioactive material screening

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Radiation Detection Technology and Methods 2023年第1期7卷 90-99页

作者： Haiyan Du Chengbo Du Ke Han Shengming He Liqiang Liu Yue Meng Shaobo Wang Tao Zhang Wenming Zhang Li Zhao jifang zhou Shanghai Laboratory for Particle Physics and Cosmology Key Laboratory for Particle Astrophysics and Cosmology(MOE)School of Physics and AstronomyINPACShanghai Jiao Tong UniversityShanghai200240China Yalong River Hydropower Development Company Chengdu610051China SPEIT(SJTU-ParisTech Elite Institute of Technology) Shanghai Jiao Tong UniversityShanghai200240China

Purpose Low-radioactive material screening is becoming essential for rare event search experiments,such as neutrinoless double beta decay and dark matter searches in underground laboratories.A gaseous time projection chamber(TPC)can be used for such purposes with large active areas and high *** A gaseous TPC with a Micromegas readout plane of approximately 20×20 cm^(2)is successfully constructed for surface alpha contamination *** We have characterized the energy resolution,gain stability,and tracking capability with calibration *** With the unique track-related background suppression cuts of the gaseous TPC,we have established that the alpha background rate of the TPC is(0.13±0.03)×10^(−6)Bq/cm^(2),comparable to the leading commercial solutions.

关键词： Low background Gaseous time projection chamber Background suppression

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酸性溶液作用下岩石浸泡时间尺度及劣化预测模型研究

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水利水电技术（中英文） 2021年第8期52卷 162-171页

作者：周济芳雅砻江流域水电开发有限公司四川成都610051

为了研究水岩作用对岩体劣化的影响,针对在pH值较低的溶液中试样浸泡效果不明显、浸泡时间长,且长时间浸泡对结果影响较大等问题,以三峡库区库岸边坡砂岩为研究对象,基于不同pH值的化学溶液对岩石的侵蚀作用,对岩石浸泡时间尺度问题及... 详细信息

为了研究水岩作用对岩体劣化的影响,针对在pH值较低的溶液中试样浸泡效果不明显、浸泡时间长,且长时间浸泡对结果影响较大等问题,以三峡库区库岸边坡砂岩为研究对象,基于不同pH值的化学溶液对岩石的侵蚀作用,对岩石浸泡时间尺度问题及浸泡损伤后的强度模型展开研究。以H+物质的量为指标,运用高浓度的硫酸溶液在较短时间内对低浓度的反应速度和低浓度溶液在较长时间内的化学侵蚀效果做出模拟。同时,分析了浸泡时间周期对砂岩试样的影响,得到了砂岩腐蚀浸入深度与浸泡时间的关系。结果表明:当拟合次数达到4阶时,拟合曲线已基本和数据点重合,说明采用高浓度硫酸溶液的反应来模拟低浓度酸溶液与岩体的反应是可行的;对于较低的pH值,按小时统计的H^(+)物质的量的变化量的变化显得缺乏规律;随着浸泡时间的增加,H^(+)反应面由表及里逐渐深入,浸入路径也不断拉长,导致腐蚀浸入速率也逐渐放缓。砂岩的强度参数对岩石劣化损伤模型的准确性验证分析表明,预测模型能较好地反应岩体劣化后强度的变化趋势。

关键词：劣化作用化学溶液浸泡时间尺度损伤模型

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3 - 83 Did Resistant Cells in 786-O Cell Line Express Candidate Cell Surface Marker of CSCs？

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IMP & HIRFL Annual Report 2010年第1期 185-186页

作者： Song Lei Ye Wenling Li Junhong Hao jifang Hu Burong zhou Guangming

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3 - 89 Comparison Radiosensitization by Fludarabine Combined with Different Ionizing Irradiation in 786-0 Cell Line

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IMP & HIRFL Annual Report 2010年第1期 192-193页

作者： Song Lei Li Junhong Ye Wenling Wang Jufang Hao jifang zhou Guangming

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基于爆破卸压地应力快速释放的强岩爆防治方法与效果评价研究

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工程科学与技术 2018年第4期50卷 22-29页

作者：吴世勇周济芳杜成波雅砻江流域水电开发有限公司四川成都610051

深埋隧洞强岩爆灾害是制约工程开挖施工安全和高效实施的难题,科学爆破开挖设计已成为有效控制强岩爆灾害的重要技术手段。针对锦屏二级引水隧洞工程随隧洞埋深增加、地应力增大所频现的强岩爆灾害的防控问题,对爆破卸压方法的强岩爆防... 详细信息

深埋隧洞强岩爆灾害是制约工程开挖施工安全和高效实施的难题,科学爆破开挖设计已成为有效控制强岩爆灾害的重要技术手段。针对锦屏二级引水隧洞工程随隧洞埋深增加、地应力增大所频现的强岩爆灾害的防控问题,对爆破卸压方法的强岩爆防治效果开展了数值仿真设计与现场试验研究。围岩内双排倾斜辐射孔和掌子面垂直超前孔两种爆破卸压方法的数值论证结果表明:前者可在左侧边墙爆破孔及拱顶中部附近、右侧拱腰下部和拱肩爆破孔附近形成了应力松弛区,应力集中部位从轮廓线附近转移到距轮廓线约5.0 m的围岩深部,后者通过爆破卸压作用在掌子面前方产生一定延伸范围的松弛区,可有效释放掌子面处的集中应力。进一步基于拉森斯岩爆判别法对比两方案的岩爆防治效果表明原来可能发生强烈岩爆的部位,采用爆破卸压释放应力后岩爆烈度等级均降低为弱岩爆,掌子面发生岩爆的可能性也显著降低。现场试验验证研究进一步论证了基于爆破卸压理论的快速应力释放方法来防治岩爆的可行性和有效性,并深入分析了两种爆破卸压方案对强岩爆防治的优势。综合研究成果并结合现场实际应用情况,提出了锦屏二级引水隧洞工程岩爆防治的综合措施,为强岩爆环境下爆破开挖设计和施工提供方法与理论支撑。

关键词：爆破卸压深埋隧洞快速应力释放强岩爆防治数值仿真现场试验

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锦屏二级水电站复杂超长引水发电系统水力过渡过程复核计算研究

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水力发电学报 2015年第1期34卷 107-116页

作者：吴世勇周济芳申满斌雅砻江流域水电开发有限公司成都610051

位于四川省雅砻江下游的锦屏二级水电站装机480万千瓦,第一台机组已于2012年12月投产发电,其引水发电系统四条引水隧洞平均长度16.67km,具有距离长、断面大、规模大等特点,可研阶段做了大量的计算分析工作,招标施工图阶段由于各种原因... 详细信息

位于四川省雅砻江下游的锦屏二级水电站装机480万千瓦,第一台机组已于2012年12月投产发电,其引水发电系统四条引水隧洞平均长度16.67km,具有距离长、断面大、规模大等特点,可研阶段做了大量的计算分析工作,招标施工图阶段由于各种原因对引水发电系统相关结构进行了一些重大调整。为确保引水发电系统水力过渡过程的安全可靠性,先后开展了大量的计算分析和模型试验工作。总结回顾了锦屏二级电站的引水发电系统的特点及工程建设中的变化,并对多家单位的计算结果进行了总结比较,分析了电站在大波动工况系统参数的极值、小波动工况系统的运行稳定性、水力干扰工况机组的出力变幅等,研究成果对工程的安全稳定运行有较大应用价值。

关键词：工程水力学锦屏二级引水发电:过渡过程计算复核模型试验

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Waveform simulation in PandaX-4T

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Chinese Physics C 2024年第7期48卷 1-13页

作者：李家富阿卜杜萨拉姆薄子豪陈葳谌勋程晨成赵侃崔祥仪樊英杰方德清耿立升 Karl Giboni 郭绪元韩晨成韩柯何昶达何金荣黄迪黄俊挺黄周侯汝全侯钰季向东巨永林李晨翔李名川李帅杰李涛林箐刘江来陆聪聪芦晓盈罗棱尹罗云阳马文博马余刚冒亚军孟月宁旭阳庞彬宇祁宁春钱志成任祥祥 Nasir Shaheed 尚晓凤邵熙元申国防司琳孙文良谈安迪陶奕王安庆王萌王秋红王少博王思广王为王秀丽王旭王舟魏月环武蒙蒙邬维浩吴渊肖梦姣肖翔燕斌斌阎玺宇杨勇喻纯旭袁影苑哲运有辉曾鑫宁张敏桢张鹏张世博张澍张涛张威张洋张瀛心张园园赵力周济芳周宁周小朋周永周钰博周知震 School of Physics and Astronomy Shanghai Jiao Tong UniversityKey Laboratory for Particle Astrophysics and Cosmology(MoE)Shanghai Key Laboratory for Particle Physics and CosmologyShanghai 200240China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China School of Physics Beihang UniversityBeijing 102206China International Research Center for Nuclei and Particles in the Cosmos&Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang UniversityBeijing 100191China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China School of Physics Peking UniversityBeijing 100871China Yalong River Hydropower Development Company Ltd.288 Shuanglin RoadChengdu 610051China Research Center for Particle Science and Technology Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Key Laboratory of Particle Physics and Particle Irradiation of Ministry of Education Shandong UniversityQingdao 266237China Department of Physics University of MarylandCollege ParkMaryland 20742USA Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghai200240China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Physics Sun Yat-Sen UniversityGuangzhou 510275China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China School of Physics and Astronomy Sun Yat-Sen UniversityZhuhai 519082China School of Physics Nankai UniversityTianjin 300071China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Shanghai Jiao Tong University Sichuan Research Institute Chengdu 610213China SJTU Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China Department of Physics Yantai UniversityYantai 264005Ch

Signal reconstruction through software processing is a crucial component of the background and signal models in the PandaX-4T experiment,which is a multi-tonne dark matter direct search *** accuracy of signal reconstruction is influenced by various detector artifacts,including noise,dark count of photomultiplier,photoionization of impurities in the detector,and other relevant *** this study,we presented a detailed description of a semi-data-driven approach designed to simulate a signal *** work provides a reliable model for the efficiency and bias of the signal reconstruction in the data analysis of *** comparing critical variables that relate to the temporal shape and hit pattern of the signals,we found good agreement between the simulation and data.

关键词： dark matter time projection chamber simulation

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Clinicopathological significance and immunotherapeutic outcome of claudin 18.2 expression in advanced gastric cancer:A retrospective study

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Chinese Journal of Cancer Research 2024年第1期36卷 78-89页

作者： Changsong Qi Xiaoyi Chong Ting zhou Mingyang Ma jifang Gong Miao Zhang Jian Li Jun Xiao Xiaohui Peng Zhen Liu Zonghai Li Lin Shen Xiaotian Zhang State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchDepartment of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Gastrointestinal OncologyPeking University Cancer Hospital&InstituteBeijing 100142China CARsgen Therapeutics Co. LtdShanghai 200231China CARsgen Life Sciences Co. LtdShanghai 200131China

Objective: Immunotherapeutic outcomes and clinical characteristics of claudin 18 isoform 2 positive(CLDN18.2-positive) gastric cancer(GC) vary in different clinical studies, making it difficult to optimize antiCLDN18.2 therapy. We conducted a retrospective analysis to explore the association of CLDN18.2 expression with clinicopathological characteristics and immunotherapeutic outcomes in ***: A total of 536 advanced GC patients from 2019 to 2021 in the CT041-CG4006 and CT041-ST-01clinical trials were included in the analysis. CLDN18.2 expression on ≥40% of tumor cells(2+, 40%) and CLDN18.2 expression on ≥70% of tumor cells(2+, 70%) were considered the two levels of positively expressed GC. The clinicopathological characteristics and immunotherapy outcomes of GC patients were analyzed according to CLDN18.2 expression ***: CLDN18.2 was expressed in 57.6%(cut-off: 2+, 40%) and 48.9%(cut-off: 2+, 70%) of *** death-ligand 1(PD-L1) and CLDN18.2 were co-expressed in 19.8% [combined positive score(CPS)≥1, CLDN18.2(cut-off: 2+, 40%)] and 17.2% [CPS≥5, CLDN18.2(cut-off: 2+, 70%)] of ***18.2 expression positively correlated with younger age, female sex, non-gastroesophageal junction(nonGEJ), and diffuse phenotype(P<0.001). HER2 and PD-L1 expression were significantly lower in CLDN18.2-positive GC(both P<0.05). Uterine adnexa metastasis(P<0.001) was more frequent and liver metastasis(P<0.001)was less common in CLDN18.2-positive GC. Overall survival and immunotherapy-related progression-free survival(ir PFS) were inferior in the CLDN18.2-positive ***: CLDN18.2-positive GC is associated with poor prognosis and worse immunotherapeutic outcomes. The combination of anti-CLDN18.2 therapy, anti-PD-L1/PD-1 therapy, and chemotherapy for GC requires further investigation.

关键词： Gastric cancer claudin18.2 CT041 PD-L1 immunotherapy

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