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Elaborating Polyurethane Pillowy Soft Mat on Polypropylene Monofilament Surface with Stepwise Surface Treatments

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Chinese Journal of Polymer Science 2022年第11期40卷 1389-1401页

作者： Chen-Xu Tian Tao Zhang Yuan-qing Song Hao Ming Peng-qing Liu Meng-Jing Jiang Feng Luo jie-Hua Li Hong tan Qiang Fu College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

The dissatisfactory mechanical compliance between stiff polypropylene(PP)and soft human tissue is one of the main factors causing the implanted complication of PP mesh devices such as chronic abdominopelvic pain and mesh *** work aims to improve the mechanical compliance of PP monofilament to human tissue without compromising the mechanical properties by elaborating polyurethane pillowy soft mat on the PP monofilament *** polarity pretreatment with dopamine-sedimentation,stiff PP monofilament can be wrapped up facilely and tightly in soft polyurethane to obtain PU/PP complex fiber with a core-shell ***,the interfacial shear strengths(IFSS)between stepwise treated PP monofilament and PU mat can effectively increase 586%compared to raw *** work provides a promising surface modification strategy to improve the interfacial adhesion between PP monofilament and PU *** obtained novel PU/PP complex fiber with pillowy soft mat would be a potential application in abdominal wall defects,hernia repair and pelvic organ prolapsed surgery.

关键词： Polypropylene monofilament Polyurethane Interfacial adhesion Surface treatment Dopamine-sedimentation

Modeling vibration behavior of delaminated composite laminates using meshfree method in Hamilton system

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Applied Mathematics and Mechanics(English Edition) 2015年第5期36卷 633-654页

作者： jie CHEN Hai WANG Guanghui qing School of Aeronautics and Astronautics Shanghai Jiao Tong University College of Aeronautical Engineering Civil Aviation University of China

Free vibration analysis of composite laminates with delaminations is performed based on a three-dimensional semi-analytical model established by introducing the local radial point interpolation method（LRPIM） into a Hamilton system. The governing equation is derived with a transfer matrix technique and a spring layer model based on a local weak-form equivalent to the modified Hellinger-Reissner variational principle. Main superiority of the present model is that the scale of the governing equation involves only the so-called state variables at the top and bottom surfaces, and is insensitive to the thickness and the layer number of the composite laminates. Several numerical examples for analyzing the vibration frequencies and mode shapes of delaminated composite beams and plates are given to validate the model. The results are in good agreement with the pre-existing results.

关键词： interpolation superiority validate variational laminated overlapping quadrature radial insensitive symmetric

Projected increases in population exposure of daily climate extremes in eastern China by 2050

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Advances in Climate Change Research 2021年第6期12卷 804-813页

作者： SUN Shao DAI tan-Long WANG Zun-Ya CHOU jie-Ming CHAO qing-Chen SHI Pei-Jun Laboratory for Climate Studies National Climate CenterChina Meteorological AdministrationBeijing100081China Cooperative Institute for Research in Environmental Sciences University of ColoradoBoulderCO80309USA Faculty of Geographical Science Beijing Normal UniversityBeijing100875China

Climate extremes pose severe threats to human health,economic stability and environmental sustainability,especially in densely populated *** is generally believed that global warming drives increase in frequency,intensity and duration of climate extremes,and socioeconomic exposure plays a dominant role in climate *** order to promote climate risk governance at regional level,the historical and projected trends in the population exposure to climate extremes are quantified in eastern China using downscaled climate simulations and population growth *** frequency of temperature extremes(tx35days)is projected to more than double by 2050 in nearly half of prefecture-level cities in eastern China,leading to an 81.8%increment of total exposure under SSP2-4.5 *** increasing trend is also detectable in the frequency of precipitation extremes(r20mm)in eastern China,and the exposure increment is projected to be 22.9%by 2050,with a near equivalent contributions of both climate change and population ***,temperature exposure mainly grows in southern Hebei,western Shandong and inland Guangdong provinces,while precipitation exposure raises principally in southeast coastal areas of *** on the historical baseline and projected amplification of population exposure,we identify some hotspot cities such as Guangzhou,Shanghai,Dongguan and Hangzhou that response to climate change dramatically and confront greater potential risk of climate extremes in the coming future.

关键词： Climate projection Extreme events Population exposure Future scenario Eastern China

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang Hui-Na Liu Yu-Fan Yang Zhi-Cheng Zhang Qi Dai Xiao-Yan Bao Lin-jie Wu Ya-Xin Qin Xin tan Xiao-Yan Sun Xu-Fang Ying Zhi-qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin

Collision risk assessment of reduced aircraft separation minima in procedural airspace using advanced communication and navigation

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Chinese Journal of Aeronautics 2023年第4期36卷 315-337页

作者： qing CAI Hao jie ANG Sameer ALAM Air Traffic Management Research Institute School of Mechanical&Aerospace EngineeringNanyang Technological University639798Singapore

With the advancement of Communication,Navigation and Surveillance(CNS)technolo-gies such as space-based Automatic Dependent Surveillance-Broadcast/Contract(ADS-B/C),large separation minima may be reduced in procedural *** is of great significance to know the upper limit of the Reduced Separation Minima(RSM)for a procedural airspace and the corre-sponding consequences on collision risk with specifics of the advanced ADS-B and control interven-tion *** this work,an interactive software is first developed for collision risk *** software integrates the International Civil Aviation Organization(ICAO)collision risk models for lateral and longitudinal collision risk calculation for the Singapore procedural *** demonstrate that the lateral and longitudinal collision risk of Singapore procedural airspace with respect to current control procedures meets the ICAO Target Level of Safety(TLS)***,the feasibility of reducing the horizontal separations implemented in the Singapore pro-cedural airspace with respect to advanced CNS techniques is *** is found that if advanced CNS technologies are applied,then the current 50-NM lateral and longitudinal separa-tion standards can be reduced to 22 NM(1 NM=1.825 km)and 20 NM,respectively,to meet the TLS standards based on current demand.A method is then devised to expand the traffic demand by p for p∈[10%,200%].It is found that the minimum lateral and longitudinal separa-tions can be reduced from 50 NM to be within the range of[23,31]NM,and 20 NM,respectively,for p∈[10%,200%],while the collision risk still meets the TLS standards.

关键词： Air transportation Collision risk Procedural airspace Separation minima Space-based Automatic Dependent Surveillance-Bro adcast/Contract(ADS-B/C)

Centralized Control Implementation Using Distributed Observer for Meglev Systems 36

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Centralized Control Implementation Using Distributed Observe...

Ferroptosis:a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury

第36届中国控制会议

作者： Qiang Chen Ying tan qing Yang jie Li Iven Mareels College of Mechatronics Engineering and Automation National University of Defense Technology

ISBN: (纸本)9781538629185

In the control of maglev systems,decentralized control structure is widely used due to its *** to the existence of mechanical coupling,the performance of decentralized control is *** paper focuses on designing a centralized controller for a small maglev platform that already has a decentralized control structure.A distributed reduced-order observer is first proposed for one suspension point to estimate the state of other suspension points using the model of the ***,a centralized control is designed and implemented with the help of the proposed decentralized *** simulation results show that centralized control based on distributed observer can reject the state coupling of maglev system and improve the maglev control performances *** future,the proposed distributed observer based centralized controller will be tested on the small maglev platform.

关键词： Maglev Centralized Control Distributed Observer

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Neural Regeneration Research 2023年第3期18卷 506-512页

作者： qing-Sheng Li Yan-jie Jia Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Academy of Medical Sciences Zhengzhou UniversityZhengzhouHenan ProvinceChina

Ferroptosis,a new non-necrotizing programmed cell death(PCD),is driven by iron-dependent phospholipid *** plays a key role in secondary traumatic brain injury and secondary spinal cord injury and is closely related to inflammation,immunity,and chronic *** inhibitors against ferroptosis effectively improve iron homeostasis,lipid metabolism,redox stabilization,neuronal remodeling,and functional recovery after *** this review,we elaborate on the latest molecular mechanisms of ferroptosis,emphasize its role in secondary central nervous trauma,and update the medicines used to suppress ferroptosis following injuries.

关键词： ferroptosis immune response inflammation iron homeostasis lipid metabolism medicine programmed cell death spinal cord injury traumatic brain injury

Morphologies of a spherical bimodal polyelectrolyte brush induced by polydispersity and solvent selectivity

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Chinese Physics B 2021年第6期30卷 637-647页

作者： qing-Hai Hao jie Cheng College of Science Civil Aviation University of ChinaTianjin 300300China

It is commonly realized that polydispersity may significantly affect the surface modification properties of polymer brush systems. In light of this, we systematically study morphologies of bidisperse polyelectrolyte brush grafted onto a spherical nanocolloid in the presence of trivalent counterions using molecular dynamics simulations. Via varying polydispersity, grafting density, and solvent selectivity, the effects of electrostatic correlation and excluded volume are focused, and rich phase behaviors of binary mixed polyelectrolyte brush are predicted, including a variety of pinned-patch morphologies at low grafting density and micelle-like structures at high grafting density. To pinpoint the mechanism of surface structure formation, the shape factor of two species of polyelectrolyte chains and the pair correlation function between monomers from different polyelectrolyte ligands are analyzed carefully. Also, electrostatic correlations, manifested as the bridging through trivalent counterions, are examined by identifying four states of trivalent counterions. Our simulation results may be useful for designing smart stimuli-responsive materials based on mixed polyelectrolyte coated surfaces.

关键词： surface morphologies polydisperse polyelectrolyte brush solvent selectivity molecular dynamics simulation

Conformal Ricci flow on asymptotically hyperbolic manifolds

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Science China Mathematics 2019年第1期62卷 157-170页

作者： Peng Lu jie qing Yu Zheng Department of Mathematics University of Oregon Department of Mathematics University of California at Santa Cruz School of Mathematical Sciences East China Normal University

In this article, we study the short-time existence of conformal Ricci flow on asymptotically hyperbolic manifolds. We also prove a local Shi's type curvature derivative estimate for conformal Ricci flow.

关键词： conformal Ricci flow asymptotically hyperbolic manifolds short time existence local Shi's curvature derivative estimates