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基于掺TiO_(2)光纤的拉曼放大器特性研究

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光电子．激光 2024年第3期35卷 234-240页

作者：高睿杰杨立春巩稼民卢姣姣郭刘飞刘威西安邮电大学电子工程学院陕西西安710121 企鹅网络科技有限公司广东深圳518000 西安邮电大学通信与信息工程学院陕西西安710121

为探索能够应用于集总式拉曼放大的新型光纤材料,采用掺TiO_(2)光纤作为增益介质分别设计了一阶、二阶拉曼放大器。给出了高功率转换效率且增益平坦的泵浦参数配置方案,在总泵浦光功率不变的情况下对比了掺TiO_(2)光纤的一阶、二阶拉曼... 详细信息

为探索能够应用于集总式拉曼放大的新型光纤材料,采用掺TiO_(2)光纤作为增益介质分别设计了一阶、二阶拉曼放大器。给出了高功率转换效率且增益平坦的泵浦参数配置方案,在总泵浦光功率不变的情况下对比了掺TiO_(2)光纤的一阶、二阶拉曼放大器与掺GeO_(2)光纤的二阶拉曼放大器的增益特性。仿真结果表明,在L波段60nm的谱宽范围内,32dBm的泵浦光前向注入长达6 km的掺TiO_(2)光纤对3 dBm的信号光进行二阶拉曼放大,其功率转换效率可达41.57%,增益平坦度仅为1.14 dB,对比掺GeO_(2)光纤的二阶拉曼放大器具有更平稳的输出增益。

关键词：集总式拉曼放大掺TiO_(2)光纤二阶拉曼放大 L波段

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大白菜制种幼苗越冬预测模型的建立

北方园艺 2024年第1期 16-23页

作者：马朝喜肖兴中李冰王梅卢娇娇原玉香河南省济源产城融合示范区农业科学院河南济源459000 河南省农业科学院蔬菜研究所河南郑州450002

以20份越冬大白菜幼苗为试材,采用灰色关联度分析法,对大白菜幼苗形态特征进行分析并筛选适宜的形态特征指标,以期为制种大白菜幼苗越冬形态特征建立预测模型。结果表明:“冬前”大白菜幼苗的地上鲜质量、单株叶面积、叶片数、根茎粗、... 详细信息

以20份越冬大白菜幼苗为试材,采用灰色关联度分析法,对大白菜幼苗形态特征进行分析并筛选适宜的形态特征指标,以期为制种大白菜幼苗越冬形态特征建立预测模型。结果表明:“冬前”大白菜幼苗的地上鲜质量、单株叶面积、叶片数、根茎粗、侧根数等形态特征与越冬率高度关联(关联系数分别为0.7981、0.7506、0.7352、0.7074、0.6769),各个指标充分反映了幼苗越冬能力。以所选“冬前”形态指标相对值为自变量,构建预测模型Y=68.885+0.963X_(1)-0.011X_(2)-0.168X_(3)+10.983X_(5)+0.116X_(7)。经回代检验,模型准确率超过97.00%。利用均方根误差(1.4053)和相对误差(0.0148)对模型评价,其预测值高度精确,能够有效地预测制种大白菜幼苗越冬率。综合各项指标表明,利用灰色关联分析法建立的模型非常可靠,能够用于露地大白菜幼苗越冬率预测模型的建立,为基层技术人员提供有力的技术参考依据。

关键词：大白菜越冬形态特征预测模型灰色关联度

Strip segmentation of oceanic internal waves in SAR images based on TransUNet

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Acta Oceanologica Sinica 2023年第10期42卷 67-74页

作者： Kaituo Qi Hongsheng Zhang jiaojiao lu Yinggang Zheng Zhouhao Zhang College of Ocean Science and Engineering Shanghai Maritime UniversityShanghai 201306China Translational Research Institute of Brain and Brain-Like Intelligence Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghai 200434China

The development of oceanic remote sensing artificial intelligence has made possible to obtain valuable information from amounts of massive *** internal waves play a crucial role in oceanic *** obtain oceanic internal wave stripes from synthetic aperture radar(SAR)images,a stripe segmentation algorithm is proposed based on the TransUNet framework,which is a combination of U-Net and Transformer,which is also *** adjusting the number of Transformer layer,multi-layer perceptron(MLP)channel,and Dropout parameters,the influence of over-fitting on accuracy is significantly weakened,which is more conducive to segmenting lightweight oceanic internal *** results show that the optimized algorithm can accurately segment oceanic internal wave ***,the optimized algorithm can be trained on a microcomputer,thus reducing the research *** proposed algorithm can also change the complexity of the model to adapt it to different date ***,TransUNet has immense potential for segmenting oceanic internal waves.

关键词： oceanic internal waves deep learning stripe segmentation synthetic aperture radar TransUNet

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三甲硅基封端苯基硅氧烷低聚物的合成研究

有机硅材料 2024年第2期38卷 36-39页

作者：殷永彪路姣姣叶文波王全唐红定武汉大学化学与分子科学学院有机硅化合物及材料教育部工程研究中心武汉430072 东莞市贝特利新材料有限公司广东东莞523143

以苯基三甲氧基硅烷和六甲基二硅氧烷为主要原料,研究了黏度19~30 mm^(2)/s、折射率1.458~1.462的三甲硅基封端苯基硅氧烷低聚物的合成方法,以及单官能团链节M与三官能团链节T物质的量之比(M/T)、回流时间、蒸馏温度等条件对产品黏度、... 详细信息

以苯基三甲氧基硅烷和六甲基二硅氧烷为主要原料,研究了黏度19~30 mm^(2)/s、折射率1.458~1.462的三甲硅基封端苯基硅氧烷低聚物的合成方法,以及单官能团链节M与三官能团链节T物质的量之比(M/T)、回流时间、蒸馏温度等条件对产品黏度、收率和甲氧基残留的影响。确定最佳合成条件为M/T=2.05,回流反应6 h,110℃蒸馏3 h,产品收率最高92.3%,黏度19.8 mm^(2)/s,折射率1.463,无色无味。

关键词：苯基三甲氧基硅烷硅氧烷低聚物 M/T比值

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高水平气手枪运动员射击技术特点分析及应用

体育科研 2024年第4期45卷 65-69,78页

作者：陆姣姣安燕刘珉王莹黄琼渝王雪羽邱俊上海体育科学研究所(上海市反兴奋剂中心) 上海200030 上海市竞技体育训练管理中心上海202162 北京体育大学北京100084

目的:探究影响高水平射击运动员10米气手枪成绩的关键技术因素,为备战2024年巴黎奥运会、2025年粤港澳全运会期间的技术训练提供数据支撑。方法:以10名一级及以上运动员为研究对象。在备战2023年全国射击锦标赛期间,通过SCATT射击训练系... 详细信息

目的:探究影响高水平射击运动员10米气手枪成绩的关键技术因素,为备战2024年巴黎奥运会、2025年粤港澳全运会期间的技术训练提供数据支撑。方法:以10名一级及以上运动员为研究对象。在备战2023年全国射击锦标赛期间,通过SCATT射击训练系统,共采集2640发实弹射击过程的技术指标。采用主成分分析、多元回归和方差分析等方法对数据进行统计分析。结果:气手枪的专项技术可归纳为据枪稳定及击发清洁度、瞄准精度和击发前意识3个主要成分,累积贡献率63.08%,其中瞄准精度是影响成绩的主要因素。目前的高水平技术训练重视稳定性基础训练和击发技术,但未进行专门的瞄准训练,对成绩的提高还不够全面。结论:高水平气手枪训练的重点除关注击发技术外,还要重视瞄准训练。

关键词：气手枪高水平射击运动员射击技术射击成绩

Pharmacokinetics,distribution,and excretion of sodium oligomannate,a recently approved anti-Alzheimer's disease drug in China

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Journal of Pharmaceutical Analysis 2022年第1期12卷 145-155页

作者： jiaojiao lu Qiongqun Pan Jieqiang Zhou Yan Weng Kaili Chen Lv Shi Guanxiu Zhu Chunlin Chen Liang Li Meiyu Geng Zhenqing Zhang Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases College of Pharmaceutical SciencesSoochow UniversitySuzhouJiangsu215021China Shanghai Green Valley Pharma.Corp. Shanghai201203China Medicilon Preclinical Research(Shanghai)LLC Shanghai201299China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai201203China

The National Medical Products Administration has authorized sodium oligomannate for treating mild-to-moderate Alzheimer’s *** this study,an LC-MS/MS method was developed and validated to quantitate sodium oligomannate in different *** plasma pharmacokinetics,tissue distribution,and excretion of sodium oligomannate in Sprague-Dawley rats and beagle dogs were systematically *** its complicated structural composition,the absorption,distribution,metabolism,and excretion profiles of the oligosaccharides in sodium oligomannate of different sizes and terminal derivatives were *** oligomannate mainly crossed the gastrointestinal epithelium through paracellular transport following oral administration,with very low oral bioavailability in rats(0.6%-1.6%)and dogs(4.5%-9.3%).Absorbed sodium oligomannate mainly resided in circulating body fluids in free form with minimal distribution into erythrocytes and major *** oligomannate could penetrate the blood-cerebrospinal fluid(CSF)barrier of rats,showing a constant area under the concentration-time curve ratio(CSF/plasma)of approximately 5%.The cumulative urinary excretion of sodium oligomannate was commensurate with its oral bioavailability,supporting that excretion was predominantly renal,whereas no obvious biliary secretion was observed following a single oral dose to bile duct-cannulated ***,only 33.7%(male)and 26.3%(female)of the oral dose were recovered in the rat excreta within 96 h following a single oral administration,suggesting that the intestinal flora may have ingested a portion of unabsorbed sodium oligomannate as a nutrient.

关键词： Sodium oligomannate Alzheimer’s disease Pharmacokinetics LC-MS/MS Oligosaccharide

Targeted screening of an anti-inflammatory polypeptide from Rhopilema esculentum Kishinouye cnidoblasts and elucidation of its mechanism in alleviating ulcerative colitis based on an analysis of the gut microbiota and metabolites

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Food Science and Human Wellness 2024年第3期13卷 1336-1347页

作者： Ziyan Wang Qiuyue Shi Ying Feng jiaojiao Han Chenyang lu Jun Zhou Zhonghua Wang Xiurong Su State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Ningbo UniversityNingbo 315000China School of Marine Science Ningbo UniversityNingbo 315000China Key Laboratory of Aquaculture Biotechnology(Ningbo University) Ministry of EducationNingbo UniversityNingbo 315000China College of Life Sciences Tonghua Normal UniversityTonghua 134000China Shandong Beiyou Biotechnology Co. Ltd.Weifang 261000China

Ulcerative colitis(UC)is a recurrent inflammatory bowel disease that imposes a severe burden on families and *** recent years,exploiting the potential of marine bioactive peptides for the treatment of diseases has become a topic of intense research *** study revealed the mechanism underlying the protective effect of the dominant polypeptide PKKVV(Pro-Lys-Lys-Val-Val)of Rhopilema esculentum cnidoblasts against DSS-induced UC through a combined analysis of the metagenome and serum ***,the polypeptide composition of *** cnidoblasts was determined by matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF/TOF-MS).Molecular docking showed that the dominant peptide PKKVV could bind better with tumor necrosis factor-α(TNF-α)than the original *** animal experiments suggested that PKKVV could modulate disorganized gut microorganisms in mice with UC;affect serum metabolites through the arachidonic acid,glycerophospholipid and linoleic acid metabolism pathways;and further alleviate UC *** study provides a reference for the comprehensive development of marine bioactive substances and nonpharmaceutical treatments for UC.

关键词： Ulcerative colitis Rhopilema esculentum Kishinouye Cnidoblasts Marine bioactive polypeptides Metagenome Serum metabolome

AI for science: Predicting infectious diseases

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Journal of Safety Science and Resilience 2024年第2期5卷 130-146页

作者： Alexis Pengfei Zhao Shuangqi Li Zhidong Cao Paul Jen-Hwa Hu jiaojiao Wang Yue Xiang Da Xie Xi lu Institute of Automation Chinese Academy of SciencesUniversity of Chinese Academy of SciencesBejing 100090China Systems Engineering Cornll UniversityIthacaNY 14853USA David Eccles School of Business the University of UtahUtahUSA Collge of Electrical Engineering Sichuan UniversityChina Department of Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Electrical Engineering Southeast UniversityNanjing 210096China

The global health landscape has been persistently challenged by the emergence and re-emergence of infectious *** epidemiological models,rooted in the early 2oth century,have provided foundational in-sights into disease ***,the intricate web of modern global interactions and the exponential growth of available data demand more advanced predictive *** is where AI for Science(AI4S)comes into play,offering a transformative approach by integrating artificial intelligence(Al)into infectious disease *** paper elucidates the pivotal role of AI4s in enhancing and,in some instances,superseding tradi-tional epidemiological *** harnessing AI's capabilities,AI4S facilitates real-time monitoring,sophisticated data integration,and predictive modeling with enhanced *** comparative analysis highlights the stark contrast between conventional models and the innovative strategies enabled by *** essence,Al4S represents a paradigm shift in infectious disease *** addresses the limitations of traditional models and paves the way for a more proactive and informed response to future *** we navigate the complexities of global health challenges,Al4S stands as a beacon,signifying the next phase of evolution in disease prediction,characterized by increased accuracy,adaptability,and efficiency.

关键词： AI for science(AI4S) Data integration Global healthchallenges Infectious disease prediction Predictive modeling Real-timemonitoring

Analysis and Characterization of the GABA Transaminase and Succinate Semialdehyde Dehydrogenase Genes in the Microalga Isochrysis zhanjiangensis in Response to Abiotic Stresses

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Journal of Ocean University of China 2024年第3期23卷 775-785页

作者： TIAN jiaojiao ZHANG Lin lu Xinyue YE Lingzhi WU Yuanyuan CHEN Deshui CAO Jiayi JIANG Jiaxin XU Jilin YAN Xiaojun Key Laboratory of Marine Biotechnology of Zhejiang Province School of Marine SciencesNingbo UniversityNingbo 315211China Key Laboratory of Aquacultural Biotechnology Ministry of Education Ningbo UniversityNingbo 315211China Laizhou Bay Marine Technology Co. Ltd.Yantai 261400China Fujian Dalai Seed Science and Technology Co. Ltd.Ningde 352101China

Gamma-aminobutyric acid(GABA),widely existing in different organisms,is rapidly accumulated in plants in response to environmental *** main biosynthesis and degradation pathways of GABA constitute the GABA shunt,which is tied to the tricarboxylic acid(TCA)*** transaminase(GABA-T)and succinate semialdehyde dehydrogenase(SSADH)are two essential enzymes for the GABA degradation *** there are abundant studies on GABA shunt in higher plants at the physiological and genetic levels,research on its role in microalgae remains *** study aimed at exploring the function of GABA-T and SSADH genes in Isochrysis zhanjiangensis,an important diet microalga,under different *** cloned two GABA-T genes,IzGABA-T1 and IzGABA-T2,and one SSADH gene IzSSADH from Isochrysis zhanjiangensis and conducted heterologous expression *** results showed that the overexpression of IzGABA-T1 or IzGABA-T2 enhanced the survival rates of yeast transformants under heat or NaCl stress,while the overexpression of IzSSADH improved yeast tolerance to NaCl stress but had no obvious effect on heat ***,the results of quantitative real-time polymerase chain reaction(qPCR)showed that IzGABA-T1 transcription increased in the HT(salinity 25,35℃)and LS(salinity 15,25℃)*** 24 h,the IzGABA-T2 transcriptions increased in the HT,LS,and HS(salinity 35,25℃)groups,but their transcription levels decreased in all groups at 48 *** transcription increased in the LS *** results suggest that IzGABA-T1,IzGABA-T2,and IzSSADH are associated with temperature and salinity stresses and possess a certain preference for different stresses.

关键词： abiotic stress GABA heterologous expression Isochrysis zhanjiangensis transcription