检索结果-南通市图书馆

健脾益肾排毒方对CKD3期患者肾脏保护作用的临床研究

在线全文

学校读者我要写书评

暂无评论

北方药学 2015年第8期12卷 108-109页

作者：谭君劲梁钰璠杨爱成陈光影梁裕聪谭健梅冼雪梅广东省江门市逢江区荷塘卫生院江门529000 江门市五邑中医院恩平分院江门529400 江门市五邑中医院江门529000

目的:探讨健脾益肾排毒方对CDK3期患者肾脏保护作用。方法:将60例CDK3期患者随机分成试验组(30例)和对照组(30例),对照组应用常规的方法进行治疗,试验组加用健脾益肾排毒方治疗。观察两组患者治疗前后肾小球滤过率(e GFR)、血肌酐、血... 详细信息

目的:探讨健脾益肾排毒方对CDK3期患者肾脏保护作用。方法:将60例CDK3期患者随机分成试验组(30例)和对照组(30例),对照组应用常规的方法进行治疗,试验组加用健脾益肾排毒方治疗。观察两组患者治疗前后肾小球滤过率(e GFR)、血肌酐、血尿素氮以及患者的生活质量和对治疗的满意度。结果:治疗后两组患者e GFR、血肌酐、血尿素氮分别与同组治疗前比较,差异有统计学意义(P<0.05)。治疗后试验组生活质量、治疗满意度与对照组比较,差异均有统计学意义(P<0.05)。结论:健脾益肾排毒方对CDK3期患者肾脏有保护作用,可提高患者生活质量。

关键词：健脾益肾排毒方慢性肾脏病肾功能生活质量

在线全文

学校读者我要写书评

暂无评论

维持性血液透析患者抑郁状态的危险因素分析

右江民族医学院学报 2021年第2期43卷 215-219页

作者：罗俊徐丽君张祥贵余万江庞淼楠谭建梅遵义医科大学第五附属(珠海)医院广东珠海519000

目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者的抑郁情况并分析其危险因素。方法选取2020年3月—2020年9月于遵义医科大学第五附属(珠海)医院规律血液透析患者162例,采用PHQ-9抑郁症筛查量表进行抑郁心情的评估,并分析其... 详细信息

目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者的抑郁情况并分析其危险因素。方法选取2020年3月—2020年9月于遵义医科大学第五附属(珠海)医院规律血液透析患者162例,采用PHQ-9抑郁症筛查量表进行抑郁心情的评估,并分析其影响因素。收集患者年龄、性别、婚姻状态等一般资料。按PHQ-9抑郁症筛查量表分为抑郁组及非抑郁组。结果162例MHD患者抑郁发生率为33.33%。抑郁组与非抑郁组比较,年龄、性别、工作情况、婚姻状态、文化程度、是否使用β受体阻滞剂、透析通路、睡眠障碍、体重指数、合并症评分差异有统计学意义(P0.05)。进一步Logistic回归发现:原发病中慢性肾炎(OR=3.578,P=0.048)、工作情况(OR=3.459,P=0.037)、使用β受体阻滞剂(OR=4.456,P=0.004)、合并症评分(OR=2.038,P=0.029)、睡眠障碍(OR=5.920,P=0.001)是MHD患者抑郁的独立危险因素。结论MHD患者抑郁发生率较正常人高。慢性肾炎、工作情况、使用β受体阻滞剂、合并症评分、睡眠障碍是MHD患者抑郁的独立危险因素。

关键词：维持性血液透析抑郁危险因素

甲状腺素及抵抗素与维持性血液透析患者抑郁状态的相关性研究

在线全文

学校读者我要写书评

暂无评论

右江民族医学院学报 2021年第4期43卷 493-496,502页

作者：徐丽君罗俊张祥贵余万江庞淼楠谭建梅遵义医科大学第五附属(珠海)医院肾内科广东珠海519100

目的维持性血液透析(MHD)患者的抑郁情况并分析与甲状腺素及抵抗素相关性。方法选取2020年3月—2020年9月于遵义医科大学第五附属(珠海)医院规律血液透析患者162例,采用PHQ-9抑郁症筛查量表进行抑郁心情的评估,并分析其影响因素。测血... 详细信息

目的维持性血液透析(MHD)患者的抑郁情况并分析与甲状腺素及抵抗素相关性。方法选取2020年3月—2020年9月于遵义医科大学第五附属(珠海)医院规律血液透析患者162例,采用PHQ-9抑郁症筛查量表进行抑郁心情的评估,并分析其影响因素。测血白蛋白、甲状腺素、抵抗素等血清学指标。按PHQ-9抑郁症筛查量表分为抑郁组及非抑郁组。结果162例MHD患者抑郁发生率为33.33%。抑郁组与非抑郁组比较,C-反应蛋白(CRP)、游离三碘甲状腺原氨酸(FT 3)、抵抗素差异有统计学意义(P0.05)。CRP(r=0.241,P=0.002)、抵抗素(r=0.382,P<0.001)、尿素(r=0.155,P=0.048)与抑郁评分呈正相关,FT 3(r=-0.188,P=0.017)与抑郁评分呈负相关。多元线性回归分析结果显示CRP、抵抗素有统计学差异(P<0.05),CRP(标准化偏回归系数β=0.205,P=0.004)、抵抗素(标准化偏回归系数β=0.333,P<0.001)是MHD患者抑郁的独立危险因素。结论MHD患者抑郁状态与CRP、抵抗素有关。

关键词：维持性血液透析抑郁危险因素

OsDMI3 Is a Novel Component of Abscisic Acid Signaling in the Induction of Antioxidant Defense in Leaves of Rice

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2012年第6期5卷 1359-1374页

作者： Ben Shi Lan Ni Aying Zhang jianmei Cao Hong Zhang Tingting Qin Mingpu tan Jianhua Zhang Mingyi-Jiang College of Life Sciences Nanjing Agricultural UniversityNanjing 210095China National Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural UniversityNanjing 210095China Department of Biology Hong Kong Baptist UniversityHong KongChina

Ca^2＋ and calmodulin （CAM） have been shown to play an important role in abscisic acid （ABA）-induced anti- oxidant defense. However, it is unknown whether Ca^2＋/CaM-dependent protein kinase （CCaMK） is involved in the pro- cess. In the present study, the role of rice CCaMK, OsDMI3, in ABA-induced antioxidant defense was investigated in leaves of rice （Oryza sativa） plants. Treatments with ABA, H2O2, and polyethylene glycol （PEG） induced the expression of OsDMI3 and the activity of OsDMI3, and H2O2 is required for the ABA-induced increases in the expression and the activity of OsDMI3 under water stress. Subcellular localization analysis showed that OsDMI3 is located in the nucleus, the cytoplasm, and the plasma membrane. The analysis of the transient expression of OsDMI3 in rice protoplasts and the RNA interference （RNAi） silencing of OsDMI3 in rice protoplasts showed that OsDMI3 is required for ABA-induced increases in the expression and the activities of superoxide dismutase （SOD） and catalase （CAT）. Further, the oxidative damage induced by higher concentrations of PEG and H202 was aggravated in the mutant of OsDMI3. Moreover, the analysis of the RNAi silencing of OsDMI3 in protoplasts and the mutant of OsDMI3 showed that higher levels of H2O2 accumulation require OsDMI3 activation in ABA signaling, but the initial H2O2 production induced by ABA is not depend- ent on the activation of OsDMI3 in leaves of rice plants. Our data reveal that OsDMI3 is an important component in ABA-induced antioxidant defense in rice.

关键词： OsDMI3 abscisic acid antioxidant defense H202 oxidative stress signal transduction.

Estimating the effect of shallow groundwater on diurnal heat transport in a vadose zone

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Earth Science 2016年第3期10卷 513-526页

作者： jianmei JIANG Lin ZHAO Zhe ZHAI School of Chemical Engineering Tianjin University Tianjin 300072 China School of Environment Science and Engineering Tianjin University Tianjin 300072 China

The influence of shallow groundwater on the diurnal heat transport of the soil profile was analyzed using a soil sensor automatic monitoring system that continu- ously measures temperature and water content of soil profiles to simulate heat transport based on the Philip and de Vries （PDV） model. Three experiments were conducted to measure soil properties at depths of 5 cm, 10 cm, 20 cm, and 30 cm when groundwater tables reached l0 cm, 30 cm, and 60 cm （Experiments I, II, and III）. Results show that both the soil temperature near shallow groundwater and the soil water content were effectively simulated by the PDV model. The root mean square errors of the temperature at depths of 5 cm, 10 cm, and 20 cm were 1.018℃, 0.909℃, and 0.255℃, respectively. The total heat flux generated the convergent and divergent planes in space-time fields with valley values of-161.5 W-m 2 at 7：30 and -234.6 W.m2 at 11：10 in Experiments II and III, respectively. The diurnal heat transport of the saturated soil occurred in five stages, while that of saturated-unsaturated and unsaturated soil profiles occurred in four stages because high moisture content led to high thermal conductivity, which hastened the heat transport.

关键词： heat transport heat flux soil temperature,water content shallow groundwater table

Immunotherapy of tumor by targeting angiogenesis

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2004年第6期47卷 545-552页

作者： HOU jianmei TIAN Ling WEI Yuquan Key Laboratory of Biotherapy of Human Diseases of Ministry of Education West China Hospital of Sichuan universityChengdu 610041China Key Laboratory of Biotherapy of Human Diseases of Ministry of EducationWest China Hospital of Sichuan universityChengdu 610041China Key Laboratory of Biotherapy of Human Diseases of Ministry of EducationWest China Hospital of Sichuan universityChengdu 610041China

Tumor growth and metastasis are angiogenesis-dependent. Anti-angiogenic therapy represents a new strategy for the development of anti-cancer therapies. In recent years, there has been made great progress in anti-angiogenic therapy. As far as the passive immunotherapy is concerned, a recombinant humanized antibody to vascular endothelial growth factor (VEGF)— Avastin has been approved by FDA as the first angiogenesis inhibitor to treat colorectal cancer. For active specific immunotherapy, various strategies for cancer vaccines, including whole en- dothelial cell vaccines, dendritic cell vaccines, DNA vaccines, and peptides or protein vaccines, have been developed to break immune tolerance against important molecules associated with tumor angiogenesis and induce angiogenesis-specific immune responses. This article reviews the angiogenesis-targeted immunotherapy of tumor from the above two aspects.

关键词： angiogenesis, tumor, immunotherapy.

Health aspects of peanuts as an outcome of its chemical composition

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2020年第1期9卷 21-30页

作者： Rabiatu Bonku jianmei Yu North Carolina Agricultural and Technical State University GreensboroNC 27411 USA

Peanut is an energy dense food item and it contains a substantial amount of fat,proteins,carbohydrate,both fat soluble and water soluble vitamins,minerals and *** are consumed worldwide due to its high nutritional value and pleasant or unique flavor after roasting or *** lipid,protein and carbohydrate not only provide energy,but also provide essential nutrients for normal body functions such as body fat and muscle *** are needed for normal cell function,growth,development,disease prevention and act as coenzymes during the production of *** to the high nutrient contents of peanuts,they have been used to combat malnutrition in most developing *** studies have associated nut consumption with a reduced incidence of cardiovascular heart diseases and gallstones in both genders and diabetes in *** evidence also suggests beneficial effects on hypertension,cancer,and *** health risk associated with peanut consumption is allergy in developed *** review discusses the health aspects,including allergy,of peanut consumption as they related to the chemical composition of peanuts using literatures published in past two decades with exceptions of a few older articles.

关键词： Peanuts Health aspects Nutrients Vitamins Peanut allergy

Evolution of humic substances in polymerization of polyphenol and amino acid based on non-destructive characterization

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2021年第1期15卷 91-100页

作者： jianmei Zou Jianzhi Huang Huichun Zhang Dongbei Yue School of Environment Tsinghua UniversityBeijing 100084China Department of Civil and Environmental Engineering Case Western Reserve UniversityClevelandOH 44106USA

Abiotic humification is important in the formation and evolution of organic matter in soil and compost maturing ***,the roles of metal oxides in abiotic humification reactions under micro-aerobic remain *** aim of this study was to use non-destructive measurement methods to investigate the role of MnO_(2) in the evolution of humic substances(HSs)during oxidative polymerization of polyphenol-amino *** results suggested a synergistic effect between MnO_(2) and O_(2) in promoting the polymerization reaction and identified that MnO_(2) alone had a limited ability in accelerating the transformation of fulvic acid(FA)to humic acid(HA),whereas O_(2) was the key factor in the ***-dimensional correlation spectroscopy(2D-COS)showed that the evolution in the UV-vis spectra followed the order of 475–525 nm>300–400 nm>240–280 nm in the humification process,indicating the formation of simple organic matter followed by FA and then HA.13C nuclear magnetic resonance(13C NMR)analysis revealed that the products under both air and N2 conditions in the presence of MnO_(2) had greater amounts of aromatic-C than in the absence of MnO_(2),demonstrating that MnO_(2) affected the structure of the humification *** results of this study provided new insights into the theory of abiotic humification.

关键词： Two-dimensional correlation spectroscopy(2D-COS) Humic substances(HSs) Humification Manganese dioxide Polyphenol

Optical flow based guidance system design for semi-strapdown image homing guided missiles

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2016年第5期29卷 1345-1354页

作者： Huang Lan Song jianmei Zhang Minqiang Cai Gaohua Key Laboratory of Dynamics and Control of Flight Vehicle Ministry of Education School of Aerospace Engineering Beijing Institute of Technology Beijing 100081 China Beijing Aerospace Automatic Control Institute Beijing 100854 China

This paper focuses mainly on semi-strapdown image homing guided （SSIHG） system design based on optical flow for a six-degree-of-freedom （6-DOF） axial-symmetric skid-to-turn missile. Three optical flow algorithms suitable for large displacements are introduced and compared. The influence of different displacements on computational accuracy of the three algorithms is analyzed statistically. The total optical flow of the SSIHG missile is obtained using the Scale Invariant Feature Transform （SIFT） algorithm, which is the best among the three for large displacements. After removing the rotational optical flow caused by rotation of the gimbal and missile body from the total optical flow, the remaining translational optical flow is smoothed via Kalman filtering. The circular navigation guidance （CNG） law with impact angle constraint is then obtained utilizing the smoothed translational optical flow and position of the target image. Simulations are carried out under both disturbed and undisturbed conditions, and results indicate the proposed guidance strategy for SSIHG missiles can result in a precise target hit with a desired impact angle without the need for the time-to-go parameter.

关键词： Guidance strategy Impact angle Optical flow Scale Invariant Feature Transform (SIFT) Semi-strapdown image homing guided (SSIHG) missile