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Advances in Applied Mathematics and Mechanics 2016年第1期8卷 67-81页

作者： Wei yao Hongwei Yang Yabei Li Guanghong Ding Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function Department of Mechanics and Engineering ScienceFudan University220 Handan RoadShanghai 200433China

Mast cells(MCs)play an important role in the immune *** connective tissues,mechanical stimuli activate intracellular calcium signaling pathways,induce a variety of mediators including leukotriene C4(LTC4)release,and affect MCs’*** paper focuses on MCs’intracellular calcium dynamics and LTC4 release responding to mechanical stimuli,explores signaling pathways in MCs and the effect of interstitial fluid flow on the transport of biological messengers and feedback in the MCs *** use a mathematical model to show that(i)mechanical stimuli including shear stress induced by interstitial fluid flow can activate mechano-sensitive(MS)ion channels on MCs’membrane and allow Ca^(2+)entry,which increases intracellular Ca^(2+)concentration and leads to LTC4 release;(ii)LTC4 in the extracellular space(ECS)acts on surface cysteinyl leukotriene receptors(LTC4R)on adjacent cells,leading to Ca^(2+)influx through Ca^(2+)release-activated Ca^(2+)(CRAC)*** elevated intracellular Ca^(2+)concentration further stimulates LTC4 release and creates a positive feedback in the MCs *** findings of this study may facilitate our understanding of the mechanotransduction process in MCs induced by mechanical stimuli,contribute to understanding of interstitial flow-related mechanobiology in MCs network,and provide a methodology for quantitatively analyzing physical treatment methods including acupuncture and massage in traditional Chinese medicine(TCM).

关键词： Mast cells Ca^(2+)signaling LTC4 release interstitial fluid flow network

Social welfare maximization for SRSNs using bio-inspired communitycooperation mechanism

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Chinese Science Bulletin 2012年第1期57卷 125-131页

作者： XU YuHua WU QiHui WANG JinLong yao YuDong Institute of Communications Engineering PLA University of Science and TechnologyNanjing 210007China Department of Electrical and Computer Engineering Stevens Institute of TechnologyNew Jersey 07030USA

This paper considers social welfare maximization for spatial resource sharing networks(SRSNs),in which multiple autonomous users are spatially located and mutual influence only occurs between nearby *** cope with a lack of central control and the restriction that only local information is available,a spatial resource sharing game is ***,individual selfishness in traditional game models generally leads to inefficiency and *** by local cooperative behavior in biological sys- tems,a community cooperation mechanism(CCM)is proposed to improve the efficiency of the ***,when a user makes a decision,it maximizes the aggregate payoffs for its local community rather than selfishly consider *** is analytically shown that with the bio-inspired CCM,the social optimum of SRSNs is achieved with an exchange of local *** proposed bio-inspired CCM is very general and can be applied to various communication networks.

关键词：社会福利合作机制最大化仿生游戏模式空间资源生物系统信息交换

Declining diagnostic accuracy of non-invasive fibrosis tests is associated with elevated alanine aminotransferase in chronic hepatitis B

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World Journal of Clinical Cases 2018年第12期6卷 521-530页

作者： Lin Wang yao-Xin Fan Xiao-Guang Dou Department of Infectious Diseases Shengjing Hospital of China Medical Uni-versity

AIM To explore the effect of alanine aminotransferase(ALT) on the performance of non-invasive fibrosis tests in chronic hepatitis B(CHB) patients. METHODS A total of 599 treatment-naive and biopsy-proven CHB patients were included in the study. The cohort was divided into the following three groups: Normal ALT(ALT ≤ 40), slightly elevated ALT(40 80). The diagnostic performance of five common non-invasive fibrosis tests for liver fibrosis(stages S2-4), including the aspartate aminotransferase(AST)-to-platelet(PLT) ratio index(APRI), fibrosis index based on 4 factors(FIB-4), King's score, Forns index and gamma-glutamyl transpeptidase(GGT)-to-PLT ratio(GPR), were evaluated for each group. RESULTS Higher ALT levels were associated with higher non-invasive fibrosis test scores. Patients with the same fibrosis stage but higher ALT levels showed higher noninvasive test scores. The areas under the receiver operating characteristics curves(AUROCs) of the noninvasive tests for prediction of ≥ S2 were higher for patients with ALT ≤ 40 U/L(range 0.705-0.755) and 40 80 U/L(range 0.604-0.701). The AUROCs for predicting ≥ S3 and S4 were higher in patients with ALT ≤ 40 U/L(range 0.736-0.814 for ≥ S3, 0.79-0.833 for S4) than in patients with 40 80 U/L(range 0.7-0.784 for ≥ S3, range 0.662-0.719 for S4). The diagnostic accuracy of the non-invasive tests decreased in a stepwise manner with the increase in *** ALT has a significant effect on the diagnostic performance of non-invasive fibrosis tests. The ALT level should be considered before performing these noninvasive tests.

关键词： Chronic hepatitis B Non-invasive tests Liver fibrosis Alanine aminotransferase Inflammation

An Investigation of Knowledge and Attitudes of Chinese English Majors Towards Plagiarism in Their English Writing

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An Investigation of Knowledge and Attitudes of Chinese Engli...

作者： Guo yao 西安外国语大学

学位级别：硕士

本研究旨在调查中国英语专业大学生对英语写作中剽窃抄袭这一概念的理解，了解和态度，目的在于从教学上寻求解决方法，帮助学生在写作中杜绝或减少这一现象。剽窃抄袭行为在学术届臭名昭著，被广为诟病。因此，各国学者，无论是在文化... 详细信息

本研究旨在调查中国英语专业大学生对英语写作中剽窃抄袭这一概念的理解，了解和态度，目的在于从教学上寻求解决方法，帮助学生在写作中杜绝或减少这一现象。剽窃抄袭行为在学术届臭名昭著，被广为诟病。因此，各国学者，无论是在文化，语言还是写作研究领域，都对这一现象高度重视。当今中国的学术界也面临着同样的情况，由剽窃抄袭而引发的丑闻在学术著作中屡见不鲜。大部分学者在研究这一现象时，都认为这是严重的学术不端行，并将其归因为学生的蓄意欺诈，缺乏学术道德，甚至是一种罪行。然而，几乎没有人深入探究这一行为的真正成因，也没有教师从改变教学内容和方法入手，来改善这一现象。久而久之，大学生群体这一剽窃抄袭行为的主体成分反而往往被学者们忽视。因为这个特殊的学生群体是未来学术写作和专业领域写作的主要力量，因此他们对剽窃抄袭的知识、态度和理解亟待研究，从而从写作教学上探索这一问题的解决之道，同时也争取通过教学培养学生规范写作的能力，引导树立他们的学术诚信。当前，中国的英语专业大学生尤其需要重视。他们身处东西方文化深度交汇的学术环境，既有根深蒂固的中文写作思维，又长时间地大量接触西方的英语写作文化。这很可能使他们混淆学术写作的标准，从而对剽窃抄袭的理解产生偏差。在这种情况下，应该对这个学生群体进行全面的，深层次的研究，实证调查他们对这一概念的了解程度、态度和理解，以及这些认识是如何随着专业学习经历的深入而发展变化。通过已有文献和理论，本文作者认为，学生剽窃的一个重要成因是其无法成功构建作者身份，对文章的所有权和独创性的意识薄弱，这是导致学生随意使用外部文献，不维护自己和他人写作产权的主要原因。因此，要了解他们引用文献的习惯性做法以及写作活动和师生互动过程会如何影响学生作者身份的构建，用以探索教学改革。本研究以此为研究目的，采用结构化采访的研究方法，选择同一所大学英语专业三个不同年级的学生为采访对象进行研究，可以为教师和学校在处理英语专业学生剽窃问题上提供科学真实的参考依据，以此实验结果调整教学目标，课程设计和授课方式，使学生在专业学习过程中的从心理认识发展方面顺应现今中国学术界的现状。

关键词：剽窃抄袭作者身份中国英语专业学生教学措施

Sonochemical Degradation of Polychlorinated Biphenyls in Aqueous Solution

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Chinese Chemical Letters 2003年第2期14卷 205-208页

作者： Xi Kui WANG Guan Hong CHEN Zhong Yan yao College of Chemistry and Environmental Science University of JinanJinan 250022

Polychlorinated biphenyl (PCB) is a kind of persistent and dangerous environmental pollutants. This paper presented the research result of sonochemical degradation of 2-chloro- biphenyl (2-CBP), 4-chlorobiphenyl (4-CBP) and 4,4-dichlorobiphenyl (4,4-CBP)in water. The ultrasonic degradation kinetics of 2-CBP, 4-CBP and 4,4-CBP in water were found to be first-order and the degradation rate coefficients are 3.69?0-2, 3.19?0-2 and 2.06?0-2 at 25?C for 2-CBP, 4-CBP and 4,4-CBP respectively. The influence of initial concentrations, reaction temperature on the ultrasonic decomposition of 2-CBP were also investigated.

关键词： Polychlorinated biphenyl degradation sonochemistry 2-chlorobiphenyl.

Propagation and Coalescence of Blast-Induced Cracks in PMMA Material Containing an Empty Circular Hole Under Delayed Ignition Blasting Load by Using the Dynamic Caustic Method

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Journal of Beijing Institute of Technology 2018年第4期27卷 547-555页

作者： Zhongwen Yue yao Song Zihang Hu Yanlong Lu School of Mechanics and Civil Engineering China University of Mining and Technology

In this paper,dynamic caustic method is applied to analyze the blast-induced crack propagation and distribution of the dynamic stress field around an empty circular hole in polymethyl methacrylate(PMMA)material under delayed ignition blasting *** following experimental results are obtained.(1)In directional-fracture-controlled blasting,the dynamic stress intensity factors(DSIFs)and the propagation paths of the blast-induced cracks are obviously influenced by the delayed ignition.(2) The circular hole situated between the two boreholes poses a strong guiding effect on the coelesence of the cracks,causing them to propagate towards each other when cracks are reaching the circular hole area.(3)Blast-induced cracks are not initiated preferentially because of the superimposed effect from the explosive stress waves on the cracking area.(4) By using the scanning electron microscopy(SEM)method,it is verified that the roughness of crack surfaces changes along the crack propagation paths.

关键词： crack propagation and coalescence dynamic caustic method delayed ignition blast-induced cracks dynamic stress intensity factor(DSIF)

Last 150-Year Variability in Japanese Anchovy (Engraulisjaponicus) Abundance Based on the Anaerobic Sediments of the Yellow Sea Basin in the Western North Pacific

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Journal of Ocean University of China 2016年第1期15卷 131-136页

作者： HUANG Jiansheng SUN yao JIA Haibo TANG Qisheng College of Ocean and Earth Sciences Xiamen University Xiamen 361005 P. R. China Yellow Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Qingdao 266071 P. R. China

Relatively short historical catch records show that anchovy populations have exhibited large variability over multi-decadal *** order to understand the driving factors(anthropogenic and/or natural) of such variability,it is essential to develop long-term time series of the population prior to the occurrence of notable anthropogenic ***-preserved fish scales in the sediments are regarded as useful indicators reflecting the fluctuations of fish populations over the last *** study aims to validate the anchovy scale deposition rate as a proxy of local anchovy biomass in the Yellow Sea adjoining the western North *** reconstructed results indicated that over the last 150 years,the population size of anchovy in the Yellow Sea has exhibited great fluctuations with periodicity of around 50 years,and the pattern of current recovery and collapse is similar to that of historical *** pattern of large-scale population synchrony with remote ocean basins provides further evidence proving that fish population dynamics are strongly affected by global and basin-scale oceanic/climatic variability.

关键词： fish scales record anchovy the central South Yellow Sea population dynamic

Review on the nanoparticle fluidization science and technology

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Chinese Journal of Chemical Engineering 2016年第1期24卷 9-22页

作者： Xiaolin Zhu Qiang Zhang yao Wang Fei Wei Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical Engineering Tsinghua University

Gas fluidization has an ability to turn static particles to fluid-like dense flow, which allows greatly improved heat transfer among porous powders and highly efficient solid processing to become reality. As the rising star of current scientific research, some nanoparticles can also be fluidized in the form of agglomerates, with sizes ranging from tens to hundreds of microns. Herein, we have reviewed the recent progress on nanomaterial agglomeration and their fluidization behavior, the assisted techniques to enhance the fluidization of nanomaterials,including some mechanical measures, external fields and improved gas injections, as well as their effects on solid fluidization and mixing behaviors. Most of these techniques are effective in breaking large agglomerates and promoting particulate fluidization, meanwhile, the solid mixing is intensified under assisted fluidization. The applications of nanofluidization in nanostructured material production and sustainable chemical industry are further presented. In summary, the fluidization science of multidimensional, multicomponent and multifunctional particles, their multi-phase characterization, and the guideline of fluidized bed coupled process are prerequisites for the sustainable development of fluidized bed based materials, energy and chemical industry.

关键词： Nanomaterial Nanoparticle Fluidization Agglomerate Assisted technique Solid mixing Application

Linking Monsoon Activity with River-Derived Sediments Deposition in the Northern South China Sea

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Journal of Ocean University of China 2019年第5期18卷 1098-1104页

作者： GE Qian XU Dong YE Liming YANG Kehong yao Zhigang Key Laboratory of Submarine Geosciences State Oceanic AdministrationHangzhou 310012China Second Institute of Oceanography Ministry of Natural ResourcesHangzhou 310012China Key Laboratory of Physical Oceanography Ocean University of ChinaQingdao 266100China

The history of the East Asian monsoon(EAM)since Last Glacial Maximum is reconstructed based on records in a sediment core retrieved from the northern South China *** provenance of organic carbon and the EAM’s evolution are investigated using combined organic carbon,grain size,and AMS 14 C dating *** to the strong winter monsoon,the marine organic matter was dominated in the sediments,andδ13 C of organic matter was high during the last glacial *** the Holocene,the primary productivity decreased and the dilution effect of riverine inorganic clastics ***,the total organic carbon contents andδ13 C values decreased,and terrestrial organic matter content increased in the core *** 4μm grain size fraction,as the environmental sensitive grain size component,is determined to reconstruct the paleoclimatic *** the last glacial period,the contents of 4μm grain size component were mainly controlled by the sea level *** the Holocene,the influence of the sea level changes weakened and the roles of current system and provenance *** correlation between the EAM and solar insolation forcing is also discussed in this paper.

关键词： organic carbon grain size sea level current system South China Sea East Asian monsoon

Synthesis of New Substituted 4-Amino-3,5-dinitropyridine Derivatives

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Chinese Journal of Chemistry 2013年第10期31卷 1299-1304页

作者： Congming Ma Yongbin Wang Kehui Hou Zuliang Liu Qizheng yao School of Chemical Engineering Nanjing University of Science & Technology Nanjing Jiangsu 210094 China School of Pharmacy China Pharmaceutieal University Nanjing Jiangsu 210009 China

Facile synthetic routes for the preparation of some new 4-amino-3,5-dinitropyridine derivatives have been revealed. Nitration of 2-chloropyridin-4-amine （1） as a starting material, in an unexpected one-step reaction, to give dinitrated derivatives, followed by nucleophilic substitution reactions with sodium azide, potassium fluoride, ammonia, methylamine, and 4-nitroimidazol, respectively, gave substituted 4-amino-3,5-dinitropyridine derivatives. Meanwhile, its azide derivative underwent a ring closure conversion into 7-amino-6-nitro-[1,2,5]oxadiazolo[3,4-b]- pyridine-1-oxide. It is of significance that all of the nucleophilic substitution reactions were carried out under mild conditions.

关键词： organic chemistry synthesis 4-amino-3,5-dinitropyridine nucleophilic substitution