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Analysis of the global T_m–T_s correlation and establishment of the latitude-related linear model

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Chinese Science Bulletin 2014年第19期59卷 2340-2347页

作者： Yibin yao Bao Zhang Chaoqian Xu Jiajun Chen School of Geodesy and Geomatics Wuhan University

In this study,the correlation between Tm,a key variable in GNSS water vapor inversion,and surface temperature(Ts)was calculated on a global scale based on the global geodetic observing system(GGOS)atmosphere Tmdata and European centre for medium-range weather forecasts(ECMWF)surface temperature *** results show that their correlation is mainly affected by latitudes,and the correlation is stronger at high latitudes and weaker at low *** the correlation is relatively weak in the tropic areas,the temperature changes so little in a year in these areas that we can still achieve good Tmresults by linear regression *** on these facts,‘‘GGOS atmosphere’’Tmdata and ECMWF Tsdata from 2005 to2011 were used to establish the global latitude-related linear regression *** new model has root mean square error(RMSE)of 3.2,3.3,and 4.4 K,respectively,compared with respect to the‘‘GGOS atmosphere’’data,COSMIC data,and radiosonde data and is more accurate than the Bevis Tm–Tsrelationship.

关键词：低纬度地区线性模型全球导航卫星系统线性回归模型均方根误差 ECMWF COSMIC 无线电探空仪

Numerical Simulations of Snow Accumulation in the Bogie Region of a Train Considering Snow Particle Rotation

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Fluid Dynamics & Materials Processing 2024年第10期20卷 2337-2352页

作者： Hong Lan Jiye Zhang yao Zhang Lu Cai State Key Laboratory of Rail Transit Vehicle System Southwest Jiaotong UniversityChengdu610031China College of Railway Transportation Hunan University of TechnologyZhuzhou412000China GD Midea Air-Conditioning Equipment Co. Ltd.Foshan528311China

To investigate the influence of snow particle rotational motion on the accumulation of snow in the bogie region of high-speed trains,an Euler‒Lagrange numerical approach is *** study examines the effects of snow particle diameter and train speed on the ensuing *** is shown that considering snow particle rotational motion causes significant deviation in the particle trajectories with respect to non-rotating *** a deviation increases with larger snow particle diameters and higher train *** snow accumulation on the overall surface of the bogie increases,and the amount of snow on the vibration reduction device varies *** certain conditions,the amount of accumulated snow can increase by several orders of magnitudes.

关键词： High-speed train bogie snow particle rotation discrete phase model snow accumulation

Construction and function of recombinant AcMNPV with double copies of v-cath gene

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Chinese Science Bulletin 2002年第1期47卷 52-57页

作者： Deli Liu Huazhong Xiao Yipeng Qi Lunguang yao Wuhan Univ Inst Virol Wuhan 430072 Peoples R China

Two recombinant baculoviruses, dciAcMNPV and dcdAcMNPV in which another copy of the v-cath gene controlled by ie1 promoter and polh promoter was inserted, were respectively constructed by the Bac-to-Bac system. The expression of the v-cath gene of the recombinant baculovi-ruses in Sf9 cells at different phases was investigated by SDS-PAGE and Western blot. The results showed that only re-combinant virus dciAcMNPV containing late gene v-cath driven by early gene promoter could express V-CATH pro-tein, cathepsin encoded by virus genome, 12 h post-infection and dcdAcMNPV containing late gene v-cath driven by late and very late gene promoters could express more V-CATH protein. Negative control ncAcMNPV, a mutant deleted v-cath gene, could not express V-CATH protein at all. The Spodopera exigua larvae were infected with viruses respec-tively and the results showed that the toxicity was as follows: dcdAcMNPV>dciAcMNPV>wtAcMNPV>ncAcMNPV. The toxicity of recombinant viruses and the characters of dead larvae

关键词： v-cath gene Western blot Bac-to-Bac system recombi-nant baculovirus.

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散粒体组构特征对系统自组织临界性的影响

四川大学学报（工程科学版） 2008年第5期40卷 27-31页

作者：李洪波姚令侃杨明中国石油大学(华东)储运与建筑工程学院山东青岛266555 西南交通大学土木工程学院四川成都610031

为验证散粒体崩塌中的自组织临界现象是否是一种有限尺度效应,自组织临界现象的发生终究由系统的尺寸还是系统的组织原则来确定,进行了均匀和非均匀散粒体崩塌的实验。实验证明影响系统自组织临界性的关键内因应为系统组构特征而并非前... 详细信息

为验证散粒体崩塌中的自组织临界现象是否是一种有限尺度效应,自组织临界现象的发生终究由系统的尺寸还是系统的组织原则来确定,进行了均匀和非均匀散粒体崩塌的实验。实验证明影响系统自组织临界性的关键内因应为系统组构特征而并非前人所认为的组元尺度或系统规模。进而采用离散单元法对均匀和非均匀砂堆的应力传递和分布状况进行了数值模拟,从孔隙率、配位数和信息熵三个指标的比较来看,非均匀散粒体系统内部颗粒之间相互充填更充分,应力分布和传递状况更趋复杂,从而系统结构更具稳定性,系统呈现自组织临界性。同时,模拟结果表明,二者应力传递路径的分维值并无明显差别,说明分形结构目前尚不能作为系统自组织临界性质的判据。

关键词：非均匀性自组织临界性散粒体崩塌

Warm up, cool down, and tearing apart in NK cell memory

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Cellular & Molecular Immunology 2018年第12期15卷 1095-1097页

作者： Lawrence Shih-Hsin Wu Jiu-yao Wang Graduate Institute of Medical Sciences China Medical UniversityTaichungTaiwanChina Department of Pediatrics Center for Allergy and Clinical Immunology ResearchCollege of MedicineNational Cheng Kung University HospitalTainanTaiwanChina

“Memories warm you up from the *** they also tear you apart.”―Haruki Murakami,Kafka on the *** of the characteristics of the human immune system,in addition to the recognition of nonself pathogens and the tolerance of self-antigens,is its memory response to previously encountered pathogens and the mounting of a stronger,faster secondary response against these same antigens.A long-held paradigm in immunologic study in vertebrates is that immune memory is restricted to the adaptive immune response via memory T and B cells,which possess two distinct features:specificity(recognizing pathogen antigen fragments through surface receptors)and longevity(proliferation and long-term survival after the first encounter).1–3 Unlike adaptive immunity,the innate immune system exhibits a rapid response against pathogens and transforming cells without a previous encounter,and this response depends on a series of default genes and proteins expressed on cell surfaces and in the cytoplasm that recognize the pathogen-associated molecular patterns(PAMPs)of ***,it was surprising to find several models of pathogen infections in invertebrates,including insects,worms,and jawless fish,that lack fully developed adaptive immunity but possess the features of antigen specificity and longevity likely involving phagocytic cells that can“recall”prior infection with limited *** fact,immune memory has recently been described in vertebrate myeloid lineages,4 in which epigenetic changes are proposed to occur in macrophages previously stimulated through pattern recognition receptors.

关键词： specificity immunity likely

Effects of Content of Chopped Glass Fibers on the Properties of Silica Filled PTFE Composites

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Journal of Materials Science and Chemical Engineering 2017年第7期5卷 36-44页

作者： Ying Yuan Haodong Lin Zehua jiang Zhifeng Chi Minghao yao Shuren Zhang National Engineering Center of Electromagnetic Radiation Control Materials University of Electronic Science and Technology of China Chengdu China State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Chengdu China

In this work, the polytetrafluoroethylene (PTFE)-based composite substrates were manufactured by mixing, calendering, hot-pressing sintering. The composition of all the samples was PTFE, SiO2 and chopped E-glass fibers. The effects of content of E-glass fibers on the properties of the SiO2 filled PTFE composites were investigated, including density, water absorption, dielectric properties (εr, tanδ), coefficient of thermal expansion (CTE) and temperature coefficient of dielectric constant (τε). The compositions of inorganic materials mixture are (62 ? x) % SiO2 + x % E-glass fiber (x: mass ratio to composites, x = 0, 1, 1.5, 2, 2.5, 3). The results show that as the content of E-glass fibers is 2.5 wt.%, this composite obtains optimal properties, including excellent dielectric properties (εr^2.9123, tanδ~0.0011), acceptable water absorption of 0.075%, temperature coefficient of dielectric constant of 10 ppm/?C and coefficient of thermal expansion of 15.87 ppm/?C.

关键词： Polymers Composite Materials PTFE Dielectric Properties E-Glass Fiber

农业机械化综合作业模式的试验研究及效益分析

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农业机械学报 2001年第3期32卷 79-82页

作者：夏萍江家伍姚天曙安徽农业大学农业工程系合肥市230036

通过对 3年黄淮海农业机械化推广项目的研究 ,提出应根据当地的农作制度和农艺要求 ,选择适宜的农业机械化综合作业模式。试验研究结果表明 :综合技术可以改良土壤 ,提高化肥和水的利用率 ,减少环境污染 ,可增产 15 %～ 17.7%、增收 19... 详细信息

通过对 3年黄淮海农业机械化推广项目的研究 ,提出应根据当地的农作制度和农艺要求 ,选择适宜的农业机械化综合作业模式。试验研究结果表明 :综合技术可以改良土壤 ,提高化肥和水的利用率 ,减少环境污染 ,可增产 15 %～ 17.7%、增收 192 4元 / hm2 。

关键词：农业机械化综合作业模式效益分析

RON in hepatobiliary and pancreatic cancers:Pathogenesis and potential therapeutic targets

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World Journal of Gastroenterology 2021年第20期27卷 2507-2520页

作者： Shao-Long Chen Guo-Ping Wang Dan-Rong Shi Shu-Hao yao Ke-Da Chen Hang-Ping yao Shulan International Medical College Zhejiang Shuren UniversityHangzhou 310000Zhejiang ProvinceChina Department of Surgical Oncology The Second Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310000Zhejiang ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Stomatology Wenzhou Medical University Renji CollegeWenzhou 325035Zhejiang ProvinceChina

The receptor protein tyrosine kinase RON belongs to the c-MET proto-oncogene *** has shown that RON has a role in cancer pathogenesis,which places RON on the frontline of the development of novel cancer therapeutic *** and pancreatic(HBP)cancers have a poor prognosis,being reported as having higher rates of cancer-related ***,to combat these malignant diseases,the mechanism underlying the aberrant expression and signaling of RON in HBP cancer pathogenesis,and the development of RON as a drug target for therapeutic intervention should be *** RON expression and signaling have been identified in HBP cancers,and also act as tumorigenic determinants for HBP cancer malignant *** addition,RON is emerging as an important mediator of the clinical prognosis of HBP ***,not only is RON significant in HBP cancers,but also RON-targeted therapeutics could be developed to treat these cancers,for example,therapeutic monoclonal antibodies and small-molecule *** them,antibody-drug conjugates have become increasingly popular in current research and their potential as novel anti-cancer biotherapeutics will be determined in future clinical trials.

关键词： RON Signal transduction Hepatobiliary Pancreatic neoplasms Molecular targeted therapy

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改性煤矸石粉对硫化胶料的抗磨耗性能的影响

中国矿业大学学报 2008年第1期37卷 84-87页

作者：赵鸣姚素玲陈清如太原理工大学煤科学与技术教育部重点实验室山西太原030024 太原理工大学矿业工程学院山西太原030024 中国矿业大学化学与环境工程学院北京100083

磨耗导致了大量的橡胶制品的损坏,设法提高橡胶制品的抗磨耗性能十分重要.通过对矿粉填充的天然橡胶磨耗过程的扫描电镜SEM相片的解析,详细分析了磨耗过程,同时根据橡胶的力化学理论,并结合SEM相片,研究了其磨耗机理.结果表明,胶料磨耗... 详细信息

磨耗导致了大量的橡胶制品的损坏,设法提高橡胶制品的抗磨耗性能十分重要.通过对矿粉填充的天然橡胶磨耗过程的扫描电镜SEM相片的解析,详细分析了磨耗过程,同时根据橡胶的力化学理论,并结合SEM相片,研究了其磨耗机理.结果表明,胶料磨耗的破坏过程与其热氧老化破坏过程相似;磨耗不仅会导致高分子链的断裂,而且可能会发生链转移反应和大分子自由基的异构化反应.提出了胶料磨耗是机械力引发的具有链式反应特征的力化学反应的结果.

关键词：煤矸石 SEM 磨耗