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珊瑚砂高压力下一维蠕变分形破碎及颗粒形状分析

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岩土力学 2018年第5期39卷 1573-1580页

作者：张小燕蔡燕燕王振波江芸倩中国矿业大学(北京)力学与建筑工程学院北京100083 中国矿业大学深部岩土力学与地下工程国家重点实验室江苏徐州221008 华侨大学岩土工程研究所福建厦门361021

珊瑚砂是一种含钙极高的海洋生物成因材料,具有高棱角性、形状不规则、易破碎等特点。通过珊瑚砂的高压一维蠕变试验,研究颗粒破碎引起颗粒分布曲线和形状因子的演化规律。借助于高速动态图像的激光粒度粒形仪器,从统计学的角度分析试... 详细信息

珊瑚砂是一种含钙极高的海洋生物成因材料,具有高棱角性、形状不规则、易破碎等特点。通过珊瑚砂的高压一维蠕变试验,研究颗粒破碎引起颗粒分布曲线和形状因子的演化规律。借助于高速动态图像的激光粒度粒形仪器,从统计学的角度分析试验前后颗粒形状随压力演化的关系,发现颗粒的形状因子,如长宽比、球形度和凹凸度等,随压力增加而逐渐增加。不同粒径的颗粒形状因子均向一个窄幅范围趋近,说明颗粒破碎具有无尺度性和自相似性的分形特性,分形维数随压力增加而逐渐增大,且趋近分形破碎极限。采用Hardin和Einav的方法计算相对破碎量,发现在两种计算方法下相对破碎量与压力呈幂函数关系,且幂指数相同。相对破碎量随时间增加的现象并不明显,说明在高压力下颗粒破碎主要为压缩破碎,且颗粒细化滑移填充孔隙引起的变形是造成蠕变的主要原因。

关键词：珊瑚砂分形颗粒形状蠕变颗粒破碎

Metal Ion Incorporation in Superamolecular Assemblies with substituted Cucurbiturils

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Metal Ion Incorporation in Superamolecular Assemblies with s...

中国化学会全国第十三届大环化学暨第五届超分子化学学术讨论会

作者： yun-qian Zhang Zhu Tao Li-mei Zhen Sai-feng Xue qian-jiang Zhu yun-jie Zhao (Institute of Applied Chemistry, Guizhou University, Guiyang 550025, China School of Chemistry and Chemical Engineering, Henan University of Technology Zhengzhou, Henan, 450052, China)

To overcome the shortage of a poor solubility in water and the common solvents for the common cucurbit[n]urils (Q[n]s), a number of full and partial substituted Q[n]s have been synthesised and reported.

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高层管理团队股权对创业企业价值重估的影响

华东经济管理 2011年第12期25卷 75-80页

作者：徐志坚蒋倩云王洪振南京大学商学院江苏南京210093

创业企业一般具有业绩高速增长的特征,在证券市场上更容易受到投资者的关注,上市后有较大的市场溢价,但在随后的时间里,企业价值存在一个价值重估的过程。那么,创业企业这样的价值重估是否与企业的股权特征有关?特别是董事会、总经理、... 详细信息

创业企业一般具有业绩高速增长的特征,在证券市场上更容易受到投资者的关注,上市后有较大的市场溢价,但在随后的时间里,企业价值存在一个价值重估的过程。那么,创业企业这样的价值重估是否与企业的股权特征有关?特别是董事会、总经理、高层管理团队的股权。该文利用在2009年12月31日前被中国证监会批准的、后来陆续在深圳证券交易所上市的、创业板公司的数据,对中国创业板上市企业的价值重估与董事会、总经理、高层管理团队股权的关系进行实证检验,最后证实了部分相关假设。

关键词：创业企业高层管理团队股权价值重估

MgCO_(3)分子的解离产物合成MgAl_(2)O_(4)分子

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原子与分子物理学报 2024年第5期41卷 22-28页

作者：崔金玉任海林赵帅程佥千蒋倩云王丽王飞营口理工学院基础教研部营口115014 大连工业大学大连116034

本研究碳酸镁MgCO_(3)分子的解离过程及其解离产物与三氧化二铝Al_(2) O_(3)合成MgAl_(2)O_(4)的微观过程.利用Gaussian 09软件采用CCSD(T)6-311++G(d,p)和M06-2x/6-311++G(d,p)方法分别计算反应物碳酸镁MgCO_(3)分子单点能和频率,并计算反应物受热分解的过程,寻找解离的过渡态.并通过高温烧结法,在实验室用MgCO_(3)和Al_(2) O_(3)粉末为原料,1450℃合成铝酸镁MgAl_(2)O_(4),通过X-ray diffraction即XRD测试表征实验产物与理论计算是一致的.

关键词：碳酸镁MgCO_(3) 三氧化二铝Al_(2)O_(3) 铝酸镁MgAl_(2)O_(4) 解离过渡态

Exploring the interaction between the gut microbiota and cyclic adenosine monophosphate-protein kinase A signaling pathway:a potential therapeutic approach for neurodegenerative diseases

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Neural Regeneration Research 2025年第11期20卷 3095-3112页

作者： Fengcheng Deng Dan Yang Lingxi Qing Yifei Chen Jilian Zou Meiling Jia qian Wang Runda jiang Lihua Huang College of Pharmacy Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina State Key Laboratory of Southwestern Chinese Medicine Resources Chengdu University of Traditional Chinese MedicineChengduSichuan ProvinceChina

The interaction between the gut microbiota and cyclic adenosine monophosphate(cAMP)-protein kinase A(PKA)signaling pathway in the host's central nervous system plays a crucial role in neurological diseases and enhances communication along the gut–brain *** gut microbiota influences the cAMP-PKA signaling pathway through its metabolites,which activates the vagus nerve and modulates the immune and neuroendocrine ***,alterations in the cAMP-PKA signaling pathway can affect the composition of the gut microbiota,creating a dynamic network of microbial-host *** reciprocal regulation affects neurodevelopment,neurotransmitter control,and behavioral traits,thus playing a role in the modulation of neurological *** coordinated activity of the gut microbiota and the cAMP-PKA signaling pathway regulates processes such as amyloid-β protein aggregation,mitochondrial dysfunction,abnormal energy metabolism,microglial activation,oxidative stress,and neurotransmitter release,which collectively influence the onset and progression of neurological *** study explores the complex interplay between the gut microbiota and cAMP-PKA signaling pathway,along with its implications for potential therapeutic interventions in neurological *** pharmacological research has shown that restoring the balance between gut flora and cAMP-PKA signaling pathway may improve outcomes in neurodegenerative diseases and emotional *** can be achieved through various methods such as dietary modifications,probiotic supplements,Chinese herbal extracts,combinations of Chinese herbs,and innovative dosage *** findings suggest that regulating the gut microbiota and cAMP-PKA signaling pathway may provide valuable evidence for developing novel therapeutic approaches for neurodegenerative diseases.

关键词： cyclic adenosine monophosphate emotional disorders gut microbiota neurodegenerative diseases neurological diseases protein kinase A reciprocal regulation signaling pathway strategy therapies

Targeting STAT3 with SH-4-54 suppresses stemness and chemoresistance in cancer stem-like cells derived from colorectal cancer

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World Journal of Clinical Oncology 2025年第2期16卷 63-75页

作者： Xu-Fan Zhang qian Chen Qin jiang Qiong-Ying Hu Department of Nuclear Medicine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 641000Sichuan ProvinceChina College of Medical Technology Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Laboratory Medicine Hospital of Mianyang Traditional Chinese MedicineChengdu 641000Sichuan ProvinceChina Department of Laboratory Medicine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

BACKGROUND Over the years,the numbers of treatment options for colorectal cancer(CRC)have increased,leading to notable improvements in the overall survival of CRC *** therapy may initially yield positive results,the development of drug resistance can result in treatment failure and cancer *** resistance is often attributed to the presence of cancer stem cells(CSCs).These CSCs not only contribute to therapeutic resistance but also play crucial roles in the initiation and development of tumor *** To investigate the antitumor effects of SH-4-54,which are mediated by targeting CSCs relative to treatment *** CSCs were enriched by culturing CRC cells in serum-free *** of stemness and IL-6/JAK2/STAT3 signaling were detected by Western *** of CSC malignancy,including proliferation,invasion,and tumor formation,were *** In this study,we employed SH-4-54,which exhibits anticancer activity in solid tumors through targeting the SH2 domain of both the signal transducer and activator of transcription(STAT)3 and the STAT5,and evaluated its effects on stemness and chemoresistance in colorectal *** expected,SH-4-54 treatment inhibited the phosphorylation of STAT3(p-STAT3)and decreased the percentage of ALDH1A1-positive CRC *** addition of SH-4-54 dissociated colorectal spheroids and decreased the expression of stemness markers,including ALDH1A1,CD44 and ***-4-54 treatment decreased IL-6/JAK2/STAT3 signaling by inhibiting p-STAT3 and thus inhibited spheroid formation by SW480 and LoVo ***,SH-4-54 treatment inhibited indicators of malignancy,including cell proliferation,invasion,and tumor formation,in CSCs in vitro and in ***,SH-4-54 treatment significantly increased chemosensitivity to *** Taken together,these results indicate that SH-4-54 is a promising molecule that exerts antitumor effects on colorectal CSCs by inhibiting STAT3 signaling.

关键词： SH-4-54 Colorectal cancer Cancer stem-like cells Stemness Chemosensitivity

Cu(CH_(3)COO)_(2)分子的解离及其产物合成CuCrO_(2)分子

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云南大学学报（自然科学版） 2022年第2期44卷 356-361页

作者：崔金玉王丽蒋倩云王聪邵思佳张方坚营口理工学院基础教研部辽宁营口115014 吉林大学原子与分子物理研究所吉林长春130000

研究醋酸铜Cu(CH_(3)COO)_(2)分子的解离过程及其解离产物与三氧化二铬Cr_(2)O_(3)合成CuCrO_(2)的微观过程.采用CCSD(T)6-311++G(d,p)和M06-2x/6-311++G(d,p)方法分别计算反应物醋酸铜Cu(CH_(3)COO)_(2)分子单点能和频率,并计算反应物... 详细信息

关键词：醋酸铜三氧化二铬亚铬酸铜解离过渡态

Maternal and fetal death associated with acute pancreatitis during pregnancy:A case report

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World Journal of Clinical Cases 2025年第10期13卷 53-58页

作者： Jin Li Qing-Yan Zhang Mei-Hong Zhang Shan-yun jiang Department of Anesthesiology Kaihua County People’s HospitalQuzhou 324300Zhejiang ProvinceChina Center for Clinical Inspection and Quarantine Kaihua County Center for Clinical Inspection and QuarantineQuzhou 324300Zhejiang ProvinceChina

BACKGROUND Acute pancreatitis in pregnancy is a rare but serious condition that can lead to high maternal mortality and fetal *** of pregnancy complicated by severe acute pancreatitis,particularly with subsequent respiratory and cardiac arrest,are rarely *** SUMMARY We present the case of a 35-year-old woman,at 36+5 weeks of gestation,who presented with paroxysmal epigastric pain accompanied by low back pain,nausea,and *** to the clinical symptoms,B-ultrasound imaging and biochemical indicators,the patient was diagnosed with acute pancreatitis and initially managed ***,3 hours after admission,the patient experienced respiratory and cardiac arrest,and the fetus *** this case,the adverse outcomes occurred due to the lack of aggressive fluid resuscitation and an active surgical *** Implementing aggressive fluid resuscitation to sustain tissue perfusion,alongside the proactive evaluation of pharmacological agents that suppress gastric acid secretion and inhibit pancreatic enzyme activity,may be beneficial in mitigating the risk of a severely adverse *** management of acute pancreatitis during pregnancy requires careful timing of surgical intervention,a thorough evaluation of the risks and benefits regarding the continuation or termination of pregnancy,and a focus on safeguarding both maternal and fetal health.

关键词： Severe acute pancreatitis Pregnancy Cardiac arrest Fetal death Case report

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各向异性量子点中的二维磁极化子效应

宁波大学学报（理工版） 2018年第4期31卷 92-98页

作者：蒋倩云王彦杰潘孝胤宁波大学理学院浙江宁波315211

本文研究了在垂直均匀磁场下各向异性量子点中具有中等电子-声子耦合强度的二维磁极化子效应.构造一个变分波函数,它由两部分的乘积组成,第一部分是相干声子态,由对声子真空态的Lee-Low-Pines变换得来;第二部分是电子波函数,由二维各向... 详细信息

本文研究了在垂直均匀磁场下各向异性量子点中具有中等电子-声子耦合强度的二维磁极化子效应.构造一个变分波函数,它由两部分的乘积组成,第一部分是相干声子态,由对声子真空态的Lee-Low-Pines变换得来;第二部分是电子波函数,由二维各向异性谐振子波函数通过特殊幺正变换得来.然后通过变分法获得极化子能谱的积分表达式.利用数值计算的结果,阐明了磁场和各向异性对小尺寸量子点的基态和第一、第二激发态能量的影响.

关键词：磁极化子电子-声子相互作用量子点