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Generating micro/nanostructures on magnesium alloy surface using ultraprecision diamond surface texturing process

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Journal of Magnesium and Alloys 2023年第4期11卷 1472-1483页

作者： Hanheng Du mengnan jiang Zuankai Wang Zhiwei Zhu Suet To State Key Laboratory of Ultra-Precision Machining Technology Department of Industrial and Systems EngineeringThe Hong Kong Polytechnic UniversityHong KongChina Department of Mechanical Engineering City University of Hong KongHong KongChina School of Mechanical Engineering Nanjing University of Science and TechnologyNanjingChina

The lightness and high strength-to-weight ratio of the magnesium alloy have attracted more interest in various ***,micro/nanostructure generation on their surfaces remains a challenge due to the flammability and *** by this,this study proposed a machining process,named the ultraprecision diamond surface texturing process,to machine the micro/nanostructures on magnesium alloy *** results showed the various microstructures and sawtooth-shaped nanostructures were successfully generated on the AZ31B magnesium alloy surfaces,demonstrating the effectiveness of this proposed machining ***,sawtooth-shaped nanostructures had the function of inducing the optical effect and generating different colors on workpiece *** colorful letter and colorful flower image were clearly viewed on magnesium alloy *** corresponding cutting force,chip morphology,and tool wear were systematically investigated to understand the machining mechanism of micro/nanostructures on magnesium alloy *** proposed machining process can further improve the performances of the magnesium alloy and extend its functions to other fields,such as optics.

关键词： Magnesium alloy Micro/nanostructure Ultraprecision diamond surface texturing Cutting force Chip morphology Structural color

Pathogenic microorganism biobanking in China

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Journal of Biosafety and Biosecurity 2019年第1期1卷 31-33页

作者： mengnan jiang Bo Liu Qiang Wei Office of Laboratory Management Chinese Center for Disease Control and PreventionBeijing 102206China

Pathogenic microbial strains and specimens are crucial national and strategic biological *** and management of the pathogenic microbial resources,as an integral component of biosafety,play an important role in the national biosafety system and in the overall framework of national *** preservation and management rely on the effective designation of preservation institutions,strengthened operation and management of preservation institutions,standardized description and data specifications,establishment of preservation information management systems,and promotion of resource-sharing and *** protection and efficient sharing and utility of pathogenic microbial resources are expected to make a unique contribution to the sustainable development of the national economy.

关键词： Pathogenic microorganism Preservation institutions Management

Access and benefit-sharing of the pathogenic microorganisms such as SARS-CoV-2

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Biosafety and Health 2022年第6期4卷 414-420页

作者： Yalin Zhai Geng Hong mengnan jiang Qiang Wei National Pathogen Resource Center Chinese Center for Disease Control and PreventionBeijing 102206China China Center for Food and Drug International Exchange National Medical Products AdministrationBeijing 100082China

With the outbreak of coronavirus disease 2019(COVID-19),it is essential to share pathogens and their data information safely,transparently,and *** the same time,it is also worth exploring how to share the benefits of using the provided pathogenic microorganisms fairly and *** are some mechanisms for the management and sharing of pathogenic microbial resources in the world,such as the World Health Organization(WHO),the United States,the Europe,and *** paper studies these mechanisms and puts forward"PICC"principles,including public welfare principle,interests principle,classified principle,and category principle,to strengthen cooperation,improve efficiency,and maintain biosafety.

关键词： Pathogenic microorganisms Access Benefit-sharing SARS-CoV-2

Description of the First Strain of 2019-nCoV,C-Tan-nCoV Wuhan Strain-National Pathogen Resource Center,China,2020

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China CDC weekly 2020年第6期2卷 81-82页

作者： Qiang Wei Yanhai Wang Juncai Ma Jun Han mengnan jiang Li Zhao Fei Ye Jingdong Song Bo Liu Linhuan Wu Wenjie Tan Guizhen Wu George FGao Jianjun Liu National Pathogen Resource Center Chinese Center for Disease Control and PreventionBeijingChina NHC Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChina CDCBeijingChina National Microbiology Data Center Institute of MicrobiologyChinese Academy of ScienceBeijingChina.

The recent outbreak of novel coronavirus-infected pneumonia(NCIP)in China(1)has attracted much attention domestically and *** the outbreak occurred,China carried out emergency responses quickly,notified the World Health Organization(WHO)in a timely manner,and shared the viral gene sequence with international communities immediately after pathogenic identification.

关键词： infected Strain Wuhan

Establishment of the benchmarking tool for evaluating the operation of biorepositories for pathogenic resource using a modified Delphi method

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Biosafety and Health 2024年第4期6卷 199-205页

作者： Geng Hong Dongxin Liu Yuanyuan Zhao Yalin Zhai Fengzekuan Zhao Yanhai Wang mengnan jiang Qiang Wei National Pathogen Resource Center Chinese Center for Disease Control and PreventionBeijing 102206China China Center for Food and Drug International Exchange Beijing 100082China Henan Puruixin Data Technology Co. LtdHenan 450001China Tonglu Center for Disease Control and Prevention Zhejiang 311599China National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China

In recent years,as the infectious diseases caused by pathogens such as novel coronavirus and mpox(formerly called monkeypox)spread globally,the significance of identification,preservation,and sharing of pathogenic resources become *** with the rapid development of biorepositories,it is imperative to evaluate their operation in a scientific *** using the literature review and modified Delphi method,this study develops a benchmarking tool for the comprehensive evaluation of the operation of biorepositories for pathogenic *** effective response rates of both rounds of expert surveys were 100%.The authority coefficients(Cr)were 0.82 and 0.85,respectively,manifesting the reliability of consultation *** the second‐round survey,the Kendall’s coefficient of concordance(Kendall’s W)of all indicators ranged from 0.09 to 0.31(P<0.001),the comprehensive score ranged from 4.02 to 4.94,the standard deviation ranged from 0.21 to 0.77,and the coefficient of variation(CV)ranged from 0.04 to 0.22,indicating that the expert opinions reached *** final benchmarking tool was composed of 4 primary indicators,12 secondary indicators,and 65 tertiary *** weights of the four primary indicators allocated through the rank‐sum ratio method,namely organizational structure,management requirements,biobanking capacity,and sharing capacity,were 30.50%,30.08%,25.45%,and 13.97%,*** benchmarking tool established in this study provides references for the comprehensive evaluation of the operation and puts forward advice for the sustainable development of biorepositories for pathogenic resources.

关键词： Biorepository Pathogenic resource Evaluation Benchmarking tool Modified Delphi method

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阿司匹林与眼部新生血管的生成

中华实验眼科杂志 2017年第2期35卷 184-188页

作者：江梦南沈吟邢怡桥武汉大学人民医院眼科中心 430060

阿司匹林是重要的非甾体抗炎药，通过抑制全身的环氧合酶发挥解热、镇痛、抗炎和抗血小板的作用，在心脑血管疾病及风湿免疫性疾病中被广泛使用。新生血管本是机体的一种自我修复，但同时在肿瘤及眼科各种疾病中也扮演着破坏者的角色。... 详细信息

阿司匹林是重要的非甾体抗炎药，通过抑制全身的环氧合酶发挥解热、镇痛、抗炎和抗血小板的作用，在心脑血管疾病及风湿免疫性疾病中被广泛使用。新生血管本是机体的一种自我修复，但同时在肿瘤及眼科各种疾病中也扮演着破坏者的角色。阿司匹林对病理性新生血管的产生到底发挥着何种作用，目前尚处于争论阶段：一方面，阿司匹林对于新生血管产生作用最强的作用因子血管内皮生长因子（VEGF）有一定的抑制作用；另一方面，阿司匹林又因抑制抗新生血管最强的因子，即内皮抑素生成，从而促进VEGF的生成。再者，阿司匹林对于眼部的血-视网膜屏障也有破坏作用，这在某种程度上也能造成眼底新生血管的生成。同时，我们分析了出现眼部新生血管的疾病中阿司匹林的作用。今后的研究中，阿司匹林在眼科领域与脉络膜新生血管生成中的关系急需得到进一步阐明，应综合衡量阿司匹林在新生血管防治中的利弊。

关键词：阿司匹林脉络膜新生血管血-视网膜屏障内皮抑素血管内皮生长因子

以生物安全法为遵循,推动国家病原微生物保藏体系建设

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中华实验和临床病毒学杂志 2021年第5期35卷 487-489页

作者：姜孟楠魏强中国疾病预防控制中心国家病原微生物资源库北京102206

病原微生物保藏是国家生物安全工作的重要组成部分。本文分析我国病原微生物保藏管理现状及存在的问题、提出病原微生物保藏规划思路及对策、与实现路径建议,以期更好的提高我国病原微生物资源自我保障能力,持续推进我国生物技术产业健... 详细信息

病原微生物保藏是国家生物安全工作的重要组成部分。本文分析我国病原微生物保藏管理现状及存在的问题、提出病原微生物保藏规划思路及对策、与实现路径建议,以期更好的提高我国病原微生物资源自我保障能力,持续推进我国生物技术产业健康发展。

关键词：病原微生物保藏体系规划发展

振动参数对竖直管内R124/DMAC工质鼓泡吸收特性的影响

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天津大学学报（自然科学与工程技术版） 2018年第10期51卷 1050-1055页

作者：吴曦刘嘉威蒋孟男徐士鸣王伟大连理工大学能源与动力学院海洋能源利用与节能教育部重点实验室大连116024

为配合车载余热吸收式制冷系统新型工质的研发,设计建立了一套振动状态下可视化竖直管内工质鼓泡吸收特性实验台,研究了R124(一氯四氟乙烷)/DMAC(二甲基乙酰胺)工质鼓泡吸收过程流型演化特性,探索了吸收高度与振动参数(振幅和频率)之间... 详细信息

为配合车载余热吸收式制冷系统新型工质的研发,设计建立了一套振动状态下可视化竖直管内工质鼓泡吸收特性实验台,研究了R124(一氯四氟乙烷)/DMAC(二甲基乙酰胺)工质鼓泡吸收过程流型演化特性,探索了吸收高度与振动参数(振幅和频率)之间的联系.结果表明:相对于静止状态,振动状态下鼓泡管内的两相流流型更为复杂,致使吸收高度的标准差增加,而且振动会使制冷剂气泡分布的均匀性变差,导致吸收过程中气泡间的融合更加频繁;在一定范围内,振动频率和振动幅度的增加均会使吸收高度呈现增加趋势,但当振动频率为25,Hz时,会在振幅适中(≤0.47,mm时)情况下,产生降低吸收高度的效果.

关键词：制冷剂吸收剂两相流气泡吸收振动

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加强和推进传染性疾病样本资源库建设

中国科学：生命科学 2024年第6期54卷 1082-1087页

作者：宋杨姜孟楠魏强中国疾病预防控制中心传染病管理处传染病溯源预警与智能决策全国重点实验室北京102206 中国疾病预防控制中心国家病原微生物资源库国家病原微生物保藏中心北京102206

传染性疾病样本是开展传染性疾病流行病学、疾病发生发展、临床诊断和治疗、药物筛选和疫苗研发等研究工作的重要基础性科技资源.通过顶层设计、统筹规划、依法合规、系统规范建设传染性疾病样本资源库,健全完善样本采集、检测、保藏、... 详细信息

传染性疾病样本是开展传染性疾病流行病学、疾病发生发展、临床诊断和治疗、药物筛选和疫苗研发等研究工作的重要基础性科技资源.通过顶层设计、统筹规划、依法合规、系统规范建设传染性疾病样本资源库,健全完善样本采集、检测、保藏、利用等单位间资源共建共享机制,形成连续、协同、整合的传染性疾病样本资源保藏体系,最大程度保护和有效利用这些珍贵资源,不仅对于传染性疾病科研、防控等工作至关重要,更关系国家生物安全.

关键词：传染病样本库生物安全利用