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International Journal of Minerals,Metallurgy and Materials 2014年第4期21卷 311-316页

作者： Run-lan Yu Jing Liu jian-xi tan Wei-min Zeng Li-juan Shi Guo-hua Gu Wen-qing Qin Guan-zhou Qiu School of Minerals Processing and Bioengineering Central South University Key Laboratory of Biometallurgy Ministry of Education Hunan Entry-Exit Inspection and Quarantine Bureau

The pH value plays an important role in the bioleaching of sulphide minerals. The effect of pH values on the extracellular poly-saccharide secreted by Acidithiobacillus ferrooxidans was investigated in different phases of bacterial growth during chalcopyrite bioleach-ing. It is found that extracellular polysaccharide secretion from the cells attached to chalcopyrite is more efficiently than that of the free cells in the bioleaching solution. Three factors, pH values, the concentration of soluble metal ions, and the bacterial growth and metabolism, affect extracellular polysaccharide secretion in the free cells, and are related to the bacterial growth phase. Extracellular polysaccharide secretion from the attached cells is mainly dependent on the pH value of the bacterial culture.

关键词： chalcopyrite bioleaching polysaccharides acidity Acidithiobacillusferrooxidans

中晚期鼻咽癌后程同步放化疗的前瞻性随机对照研究

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宁夏医学院学报 2004年第4期26卷 257-258,267页

作者：章耀鸿刘坚和唐喜军广东省潮州市潮州医院放疗科潮州521010

目的观察中晚期鼻咽癌后程同步放化疗的近期疗效及急性毒副反应。方法60例Ⅲ、Ⅳa期鼻咽癌随机分为同步放化疗组(治疗组)及单纯放疗组(对照组),两组放疗方法相同。治疗组在第一段放疗结束后行一周期FP方案化疗。结果治疗结束6个月时治... 详细信息

目的观察中晚期鼻咽癌后程同步放化疗的近期疗效及急性毒副反应。方法60例Ⅲ、Ⅳa期鼻咽癌随机分为同步放化疗组(治疗组)及单纯放疗组(对照组),两组放疗方法相同。治疗组在第一段放疗结束后行一周期FP方案化疗。结果治疗结束6个月时治疗组局部肿瘤消退CR率为90%(27/30),对照组CR率667%(20/30),差异有统计学意义(P005)。结论中晚期鼻咽癌后程同步放化疗可以提高局部控制率,而毒副反应无明显增加。

关键词：鼻咽肿瘤放射治疗化学治疗

Non-spherical multi-oscillations of a bubble in a compressible liquid

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Journal of Hydrodynamics 2014年第6期26卷 848-855页

作者： WANG Qian-xi YANG Yuan-xiang tan Danielle SU jian tan Soon Keat School of Mathematics University of Birmingham Maritime Research Centre School of Civil and Environmental Engineering Nanyang Technological University Sweimann Department of Mechanical Engineering National University of Singapore Nuclear Engineering Program COPPE Universidade Federal do Rio de Janeiro Nanyang Environment and Water Research Institute Nanyang Technological University

Bubble dynamics are associated with wide and important applications in cavitation erosion in many industrial systems, medical ultrasonics and underwater explosions. Two recent developments to this classical problem are reviewed in this paper. Firstly, computational studies on the problem have commonly been based on an incompressible fluid model. However, a bubble usually undergoes significantly damped oscillation due to the compressible effects. We model this phenomenon using weakly compressible theory and a modified boundary integral method. This model considers the energy loss due to shock waves emitted at minimum bubble volumes. Secondly, the computational studies so far have largely been concerned with the first-cycle of oscillation. However, a bubble usually oscillates for a few cycles before it breaks into much smaller ones. We model both the first- and second-cycles of oscillationand predict damped oscillations. Our computations correlate well with the experimental data.

关键词： compressible bubble dynamics weakly compressible theory boundary integral method

Recent advances in perovskite/organic integrated solar cells

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Rare Metals 2021年第10期40卷 2763-2777页

作者： Qiang Guo Chen-Yun Wang Tasawar Hayat Ahmed Alsaedi jian-xi Yao Zhan-Ao tan Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhou 450002China State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China NAAM Research Group Faculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100090China

The integrated perovskite/organic solar cell(IPOSC) is widely concerned as an effective approach to broaden the spectrum of perovskite solar cell(PerSC) by utilizing near-infrared light of lower bandgap organic semiconductor. Compared to tandem solar cells, the IPOSCs eliminate the preparation of the intermediate layer and simplify the manufacturing process, but retain the advantages of wide light harvesting. Meanwhile, the IPOSCs can maintain the open-circuit voltage as high as PerSCs. This review summarizes the recent developments of perovskite materials and low-bandgap organic conjugated materials applied in solar cells. Then, the working mechanism of IPOSCs and the recent developments of IPOSCs based on low-bandgap donor and acceptor materials are highlighted. Besides, the study of charge dynamic in IPOSC is summarized. Finally, the potential of IPOSCs and approach to improve device performance are also envisaged.

关键词： Organic solar cell Perovskite solar cell Perovskite/organic integrated solar cell Conjugated molecules

Atropoenantioselective synthesis of heterobiaryl N-oxides via dynamic kinetic resolution

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Science China Chemistry 2022年第12期65卷 2512-2516页

作者： xi Yuan jian Wang College of Chemistry and Materials Science Anhui Normal UniversityWuhu241002China School of Pharmaceutical Sciences Tsinghua UniversityBeijing100084China

A highly efficient enantioselective construction of heterobiaryl N-oxides was developed.A series of axially chiral heterobiaryl N-oxides were generated via the cascade reaction of aminobenzamides with heterobiaryl aldehydes in the presence of chiral phosphoric acids.A number of atropisomers were afforded in moderate to good yields with excellent enantioselectivities and *** results demonstrate that the heterobiaryl N-oxides can be utilized as efficient chiral ligands in asymmetric catalysis.

关键词： heterobiaryl N-oxides dynamic kinetic resolution chiral phosphoric acids atroposelectivity organocatalysis

A Spectrum Prediction-Based Frequency Band Pre-Selection over Deteriorating HF Electromagnetic Environment

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China Communications 2018年第9期15卷 10-24页

作者： xi Chen jian Yang School of Mechanical Engineering Nanjing University of Science and Technology The 63rd Institute National University of Defense Technology

As the earliest invented and utilized communication approach, shortwave, known as high frequency(HF) communication now experience the deterioration of HF electromagnetic environment. Finding quality frequency in efficient manner becomes one of the key challenges in HF communication. Spectrum prediction infers the future spectrum status from history spectrum data by exploring the inherent correlations and regularities. The investigation of HF electromagnetic environment data reveals the correlations and predictability of HF frequency band in both time and frequency domain. To solve this problem, we develop a Spectrum Prediction-based Frequency Band Pre-selection(SP-FBP) for HF communications. The pre-selection of HF frequency band mainly incorporated in prediction of HF spectrum occupancy and prediction of HF usable frequency, which provide the frequency band ranking of spectrum occupancy and alternative frequency for spectrum sensing, respectively. Performance evaluation via real-world HF spectrum data shows that SP-FBP significantly improves the efficiency of finding quality frequency in HF communications.

关键词： HF electromagnetic environment spectrum prediction frequency band pre-selection HF correlation HF predictability

Mitochonic acid 5 regulates mitofusin 2 to protect microglia

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Neural Regeneration Research 2021年第9期16卷 1813-1820页

作者： jian tan Shuang-xi Chen Qing-Yun Lei Shan-Qing Yi Na Wu Yi-Lin Wang Zi-jian xiao Heng Wu Department of Neurology The First Affiliated Hospital of University of South ChinaHengyangHunan ProvinceChina

Microglial apoptosis is associated with neuroinflammation and no effective strategies are currently available to protect microglia against inflammation-induced apoptosis. Mouse microglial BV-2 cells(5 × 10^6) were incubated with 10 μg/mL lipopolysaccharides for 12 hours to mimic an inflammatory environment. Then the cells were co-cultured with mitochonic acid 5(MA-5) for another 12 hours. MA-5 improved the survival of lipopolysaccharide-exposed cells. MA-5 decreased the activity of caspase-3, which is associated with apoptosis. MA-5 reduced the number of terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling-positive cells, and increased adenosine triphosphate levels in cells. MA-5 decreased the open state of the mitochondrial permeability transition pore and reduced calcium overload and diffusion of second mitochondria-derived activator of caspase(Smac). MA-5 decreased the expression of apoptosis-related proteins(mitochondrial Smac, cytoplasmic Smac, pro-caspase-3, cleaved-caspase-3, and caspase-9), and increased the levels of anti-apoptotic proteins(Bcl2 and X-linked inhibitor of apoptosis protein), mitochondria-related proteins(mitochondrial fusion protein 2, mitochondrial microtubule-associated proteins 1 A/1 B light chain 3 B II), and autophagy-related proteins(Beclin1, p62 and autophagy related 5). However, MA-5 did not promote mitochondrial homeostasis or decrease microglial apoptosis when Mitofusin 2 expression was silenced. This shows that MA-5 increased Mitofusin 2-related mitophagy, reversed cellular energy production and maintained energy metabolism in BV-2 cells in response to lipopolysaccharide-induced inflammation. These findings indicate that MA-5 may promote the survival of microglial cells via Mitofusin 2-related mitophagy in response to lipopolysaccharide-induced inflammation.

关键词： apoptosis autophagy related 5 Beclin1 BV-2 cells caspase-3 inflammation lipopolysaccharide mitophagy Smac survival

腰腿理痛散对硬膜外移植自体髓核大鼠背根节中P物质的影响

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中国中医药科技 2010年第1期17卷 17-18页

作者：张思胜潘建西谈明顺王临青甘肃省兰州市城关区中医骨伤科医院兰州730010 甘肃省兰州市西固区中医院兰州730060

目的:观察腰腿理痛散对硬膜外移植自体髓核大鼠背根节(DRG)中P物质(SP)的影响。方法:取健康Wistar大鼠50只,随机分为假手术组、模型组、腰痛宁组、腰腿理痛散高剂量组、腰腿理痛散低剂量组,每组10只,将大鼠自身的尾椎髓核取出移植于左... 详细信息

目的:观察腰腿理痛散对硬膜外移植自体髓核大鼠背根节(DRG)中P物质(SP)的影响。方法:取健康Wistar大鼠50只,随机分为假手术组、模型组、腰痛宁组、腰腿理痛散高剂量组、腰腿理痛散低剂量组,每组10只,将大鼠自身的尾椎髓核取出移植于左侧硬膜外腔L5、L6神经根背侧,造成非压迫性大鼠自体髓核移植硬膜外模型,通过免疫组化的方法测定大鼠2周时DRG中SP的变化。结果:造模各组DRG中SP阳性神经元的表达明显增加,免疫反应强度均增高,与假手术组比较P<0.05～0.01;各用药组较模型组明显降低(P<0.05),腰腿理痛散组较阳性组明显降低(P<0.05)。结论:腰腿理痛散可通过下调或者抑制非机械压迫性髓核对神经根损伤后DRG内的痛觉神经递质SP的释放而发挥镇痛作用。

关键词：椎间盘移位/中医药疗法 @腰腿理痛散/治疗应用神经递质大鼠

Dielectric-ion-conductive ZnNb2O6 layer enabling rapid desolvation and diffusion for dendrite-free Zn metal batteries

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Journal of Energy Chemistry 2025年第1期100卷 693-701页

作者： Haifeng Yang jian Wang Panpan Zhang xiaomin Cheng Qinghua Guan Jing Dong Bixian Chen Lujie Jia Jing Zhang Yongzheng Zhang Yunjian Liu Hongzhen Lin School of Materials Science and Engineering Jiangsu University i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Helmholtz Institute Ulm (HIU) Karlsruhe Institute of Technology (KIT) School of Materials Science and Engineering Xi'an University of Technology State Key Laboratory of Chemical Engineering East China University of Science and Technology

Rechargeable aqueous zinc-metal batteries （AZMBs） are promising candidates for large-scale energy storage systems due to their low cost and high ***,their performance and sustainability are significantly hindered by the sluggish desolvation kinetics at the electrode/electrolyte interface and the corresponding hydrogen evolution reaction where active water molecules tightly participate in the Zn（H2O）62+solvation ***,learnt from self-generated solid electrolyte interphase （SEI） in anodes,the dielectric but ion-conductive zinc niobate nanoparticles artificial layer is constructed on metallic Zn surface （ZNB@Zn）,acting as a rapid desolvation *** zincophilic and dielectric-conductive properties of ZNB layer accelerate interfacial desolvation/diffusion and suppress surface corrosion or dendrite formation,achieving uniform Zn plating/stripping behavior,as confirmed by electronic/optical microscopies and interface spectroscopical measurements together with theoretical ***,the as-prepared ZNB@Zn electrode exhibits excellent cycling stability of over 2000 h and robust reversibility （99.54%） even under high current density and depth of discharge ***,the assembled ZNB@Zn-based full cell displays high capacity-retention rate of 80.21%after 3000 cycles at 5 A g-1and outstanding rate performance up to 10 A *** large-areal pouch cell is stabilized for hundreds of cycles,highlighting the bright prospects of the dielectric but ion-conductive layer in further application of AZMBs.

关键词： Zn metal battery Dielectric artificial layer Rapid ion diffusion Zincophilic diffusion Active water inhibition

Essential Forward Weak KAM Solution for the Convex Hamilton–Jacobi Equation

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Acta Mathematica Sinica,English Series 2022年第5期38卷 797-806页

作者： xi Feng SU jian Lu ZHANG Laboratory of Mathematics and Complex Systems(Ministry of Education) School of Mathematical SciencesBeijing Normal UniversityBeijing 100875P.R.China Hua Loo-Keng Key Laboratory of Mathematics&Mathematics Institute Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190P.R.China

For a convex,coercive continuous Hamiltonian on a closed Riemannian manifold M,we construct a unique forward weak KAM solution of H(x,d_(x)u)=c(H)by a vanishing discount approach,where c(H)is the Ma?écritical *** als... 详细信息

关键词： Hamilton-Jacobi equation discounted equation weak KAM solution Aubry-Mather theory viscosity solution