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Hemorrhagic cystitis in gastric cancer after nanoparticle albuminbound paclitaxel:A case report

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1084-1090页

作者： Xin-Jie Zhang jian lou Department of Cancer Center The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND The advanced first-line regimen for advanced gastric cancer is based on a combination of fluoropyrimidine and platinum and/or paclitaxel(PTX),forming a two-or three-drug *** to conventional PTX,nanoparticle albumin-bound PTX(Nab-PTX)has better therapeutic effects and fewer adverse effects reported in ***-PTX is a great option for patients presenting with advanced gastric ***,we highlight an adverse event(hemorrhagic cystitis)of Nab-PTX in advanced gastric *** SUMMARY A 55-year-old male was diagnosed with lymph node metastasis after a laparo-scopic-assisted radical gastrectomy for gastric cancer that was treated by Nab-PTX and S-1(AS).On the 15th day after treatment with AS,he was diagnosed with hemorrhagic *** Physicians should be aware that hemorrhagic cystitis is a potential adverse event associated with Nab-PTX treatment.

关键词： Nanoparticle albumin-bound paclitaxel Hemorrhagic cystitis Gastric cancer Adverse event Case report

Clinical analysis of multiple primary gastrointestinal malignant tumors:A 10-year case review of a single-center

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1204-1212页

作者： Cheng-lou Zhu ling-Zhi Peng The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Surgical Oncology Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND Multiple primary malignant tumors(MPMTs)was first described by Billroth as early as 1889,with the first report published by Warren and Gates in *** then,numerous cases have been reported.A literature review of 1104269 patients with cancer revealed that the incidence of MPMTs ranged from 0.73 to 11.7%.In recent years,however,there has been a significant upward trend in the incidence of this phenomenon,which may be associated with many different factors,including the advancement of modern diagnostic procedures facilitating the examination and diagnosis of more MPMTs,increased exposure to chemotherapy and radiotherapy that exacerbate the risk of new malignant tumors in patients with cancer,and prolonged survival of patients with cancer allowing sufficient time for the development of new primary *** To analyze the incidence,clinical features,treatment factors,prevalence,and prognosis of patients with MPMTs in the gastrointestinal tract treated in a single ***,we analyzed the different tumor combinations,time interval between the occurrence of tumors,and *** This retrospective cohort study analyzed 8059 patients with pathologically confirmed gastrointestinal malignant tumors treated at the Gansu Province Hospital in Lanzhou,Gansu,China between June 2011 and June *** these,85 patients had *** clinical features,treatment factors,prevalence,and prognosis of this latter cohort were *** The incidence of MPMTs in patients with gastrointestinal malignant tumors was 1.05%(85/8059),including 83 double primary malignant tumors and two triple primary malignant tumors of which 57(67.06%)were synchronous MPMTs(SMPMTs)and 28(32.94%)were metachronous MPMTs(MMPMTs).The most frequent associations were found between the rectum colon cancers within the SMPMT category and the gastric-colon cancers within the MMPMT *** the MMPMTs,the median interval was 53 *** overall 1-,3-and 5-year survival rates f

关键词： Multiple primary malignant tumors Clinical characteristics Gastrointestinal tract Prognosis Epidemiology

Nickel Sulfide Modified NiCu Nanoalloy with Excellent Oxygen Evolution Reaction Properties Prepared through Electrospinning and Heat Treatment

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 320-326页

作者：李涛凌帅 ZHONG Shujie lou Qiongyue Department of Materials Engineering School of Mechanical EngineeringChengdu UniversityChengdu 610106China

Ni^(2+)/Cu^(2+)/SO_(4)^(2-)/polyvinyl alcohol precursor fibers with uniform diameters were prepared through ***-based composite nanoalloys containing Ni,Cu,and S were prepared through heat treatment in an Ar *** experimental results show that the main components of the prepared nanoalloys are NiCu,Ni_(3)S_(2),Ni,and *** nanoalloys exhibit fine grain sizes about 200-500 nm,which can increase with increasing heat treatment *** test results show that the nickel sulfidemodified NiCu nanoalloy composites exhibit excellent oxygen evolution reaction properties,and the oxygen evolution reaction properties gradually improve with the increasing heat treatment *** sample prepared at 1 000℃ for 40 min show a low overpotential of 423 mV and a small Tafel slope of 134 mV·dec^(-1) at a current density of 10 mA·cm^(-2).

关键词： NiCu nanoalloy Ni_(3)S_(2) structure transformation oxygen evolution reaction

Systematic CDCC calculations for ~11Be+p elastic scattering

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Science China(Physics,Mechanics & Astronomy) 2016年第3期59卷 70-74页

作者： Jie Chen jian ling lou Dan Yang Pang Yan Lin Ye School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University School of Physics and Nuclear Energy Engineering Beihang University

Continuum discretised coupled-channels(CDCC) method with a ^(10)Be(0^+) + n two-body cluster model is applied to systematically analyze the elastic scattering of the halo nucleus ^(11)Be from the proton target at various incident energies below 100 MeV/*** the renormalized ^(10)Be- p potential deduced from the ^(10)Be+ p elastic scattering data, the differential cross sections of ^(11)Be + p scattering are well reproduced by the CDCC calculations without any further adjustment parameters, demonstrating the applicability of this approach for describing the scattering of exotic nuclei based on the scattering of the less exotic core nuclei.

关键词：弹性散射计算系统混合散射微分截面耦合通道入射能量质子晕核

Pharmacotherapy of urethral stricture

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Asian Journal of Andrology 2024年第1期26卷 1-9页

作者： Hui Luo Ke-Cheng lou ling-Yu Xie Fei Zeng Jun-Rong Zou The First Clinical College Gannan Medical UniversityGanzhou 341000China Department of Urology The First Affiliated Hospital of Gannan Medical UniversityGanzhou 341000China Institute of Urology The First Affiliated Hospital of Gannan Medical UniversityGanzhou 341000China jiangxi Engineering Technology Research Center of Calculi Prevention Ganzhou 341000China

Urethral stricture is characterized by the chronic formation of fibrous tissue,leading to the narrowing of the urethral *** the availability of various endoscopic treatments,the recurrence of urethral strictures remains a common *** pharmacotherapy targeting tissue fibrosis is a promising option for reducing recurrence *** drugs cannot replace surgery,they can be used as adjuvant therapies to improve *** this regard,many drugs have been proposed based on the mechanisms underlying the pathophysiology of urethral *** studies have obtained substantial progress in treating urethral strictures,highlighting the potential for improved drug effectiveness through appropriate clinical delivery ***,this review summarizes the latest researches on the mechanisms related to the pathophysiology of urethral stricture and the drugs to provide a theoretical basis and new insights for the effective use and future advancements in drug therapy for urethral stricture.

关键词： adjuvant therapy pathophysiology pharmacotherapy urethra urethral stricture

Recent progress in subatomic particle detection technology

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Frontiers of physics 2013年第5期8卷 548-554页

作者： Zhi-Huan Li jian-ling lou Qi-Te Li Yu-Cheng Ge Zhe-Wei Yin Yan-Lin Ye School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University Beijing 100871 China

Particle detection technologies have been largely advanced in ,boratory over the past decade. A neutron sphere was built to detect the decay neutron emitted from the implanted unstable nu eleus, whereas a multi-neutron correlation spectrometer was implemented to detect the forward moving neutrons resulting from breakup reactions. Charged particle telescopes are now equipped with double sided Silicon strip detectors which have excellent energy and position resolutions. Large size gas chambers, such as resistive plate chambers, have been developed in order to achieve high Derformances related to timing or position measurements. The advances of these technologies con tribute substantially to such large science project, as LHC-CMS, and to the experiments with the radioactive nucleus beams.

关键词： subatomic particles detection nuclear physics

Ren-integrable and ren-symmetric integrable systems

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Communications in Theoretical Physics 2024年第3期76卷 62-69页

作者： S Y lou School of Physical Science and Technology Ningbo UniversityNingbo315211China

A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics,is ***-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such as super-symmetric quantum mechanics,super-symmetric gravity,super-symmetric string theory,super-symmetric integrable systems and so *** and Grassmann numbers are,in some sense,dual conceptions,and it turns out that these conceptions coincide for the ren situation,that is,a similar conception of ren-number(R-number)is devised for *** particular,some basic results of the R-number and ren-symmetry are exposed which allow one to derive,in principle,some new types of integrable systems including ren-integrable models and ren-symmetric integrable *** examples of ren-integrable KdV-type systems and ren-symmetric KdV equations are explicitly given.

关键词： symmetries integrable systems anyon physics extended supersymmetry ren-symmetry

Two annular CsI(Tl) detector arrays for the charged particle telescopes

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Nuclear Science and Techniques 2023年第10期34卷 158-165页

作者： Hong-Yu Zhu jian-ling lou Yan-Lin Ye Li-Sheng Yang Bo-Long Xia Kang Wei Ying Chen Wei-Liang Pu Zi-Yao Hu Hao-Yu Ge Jia-Hao Chen Kai Ma Wen-Wu Wan Hooi-Jin Ong Yan-Yun Yang Shi-Wei Xu Kang Wang Fang-Fang Duan Jun-Bin Ma Zhen Bai Peng Ma Ruo-Fu Chen School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Institute of Modern Physics Chinese Academy SciencesLanzhou 730000China

In this study,we constructed two annular detector arrays comprising 24 wedge-shaped CsI(Tl) crystals,and tested them using anαsource and radioactive beams of ^(14-16) Con a CD_2 *** compared the properties of a CsI(Tl) crystal encapsulated with various reflectors,revealing that using the 80-μm-thick ESR film to pack the CsI(Tl) crystal yielded the largest light output with the smallest non-uniformity in light output (ΔLO).For the 24 CsI(Tl) detectors with the 80-μm-thick ESR films,the average energy resolution improved as the average light output increased;however,it deteriorated as theΔLO value *** form two annular Si-CsI(Tl) telescopes for identifying the light-charged particles,theΔLO value and energy resolution of each CsI(Tl) detector were maintained under 20%and 7.7%,*** telescopes were tested for the first time in a direct nuclear reaction experiment using ^(14-16) C+*** results demonstrated that the Z=1 and Z=2 charged particles were adequately discriminated by the telescopes using the standardΔE-E method.

关键词： Wedge-shaped CsI(Tl)detector Light output non-uniformity Si-CsI(Tl)telescope Particle identification

Decomposition solutions and Bäcklund transformations of the B-type and C-type Kadomtsev-Petviashvili equations

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Communications in Theoretical Physics 2024年第6期76卷 34-44页

作者： Xiazhi Hao S Y lou College of Science Zhejiang University of TechnologyHangzhou 310014China School of Physical Science and Technology Ningbo UniversityNingbo 315211China

This paper introduces a modified formal variable separation approach,showcasing a systematic and notably straightforward methodology for analyzing the B-type Kadomtsev-Petviashvili(BKP)*** the application of this approach,we successfully ascertain decomposition solutions,Bäcklund transformations,the Lax pair,and the linear superposition solution associated with the aforementioned ***,we expand the utilization of this technique to the C-type Kadomtsev-Petviashvili(CKP)equation,leading to the derivation of decomposition solutions,Bäcklund transformations,and the Lax pair specific to this *** results obtained not only underscore the efficacy of the proposed approach,but also highlight its potential in offering a profound comprehension of integrable behaviors in nonlinear ***,this approach demonstrates an efficient framework for establishing interrelations between diverse systems.

关键词： decomposition solution Backlund transformation Lax pair linear superposition solution