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Fourier-domain optical coherence tomography-guided phototherapeutic keratectomy for the treatment of anterior corneal scarring

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1720-1726页

作者： Yu-Li Yang Qian jian Bo Liu Ke Wang Yu-Juan Chen Lian Tan Mei-jun Pu Yong Liu Southwest Hospital/Southwest Eye Hospital Third Military Medical University(Anny Medical University)Chongqing 400038China Chongqing Aier Mega Eye Hospital Aier Eye Hospital GroupChongqing 400060China

AIM:To evaluate the safety,visual and anatomic outcomes of fourier-domain optical coherence tomography(FD-OCT)-guided excimer laser phototherapeutic keratectomy(PTK)combined with photorefractive keratectomy(PRK)surgery in treating anterior corneal ***:Clinical data of 23 eyes of 21 patients with anterior corneal scarring underwent FD-OCT-guided PTK and PRK from Dec.2014 to Jul.2016 were *** were assessed for preoperative and postoperative uncorrected visual acuity(UCVA),best spectacle-corrected visual acuity(BSCVA),contrast sensitivity(CS),FD-OCT,corneal topography and colour figures of anterior ***:The preoperative corneal pathologic conditions included viral keratitis(7 patients,7 eyes),band keratopathy(2 patients,4 eyes),corneal dystrophy(4 patients,4 eyes),traumatic corneal disease(2 patients,2 eyes)and corneal chemical injury(6 patients,6 eyes).Mean follow-up time was 10.65(range,3-19)***(in IogMAR)improved from a mean of 0.79(95%Cl,0.281.29)preoperatively to a mean of 0.45(95%Cl,0.29-0.62)postoperatively(P=0.021).BSCVA(in IogMAR)improved from 0.57(95%Cl,0.27-0.88)preoperatively to a mean of 0.28(95%Cl,0.15-0.41)postoperatively(P=0.001).Corneal topographic indices postoperatively showed significant improvement in corneal cylinder(P=0.009),the surface regularity index(P=0.007)and surface asymmetry index(P=0.00).Postoperative spherical equivalent averaged-0.53 diopters(-1.49 to 0.42).No complications were associated with the ***:FD-OCT-guided PTK combined with PRK is safe and effective for the treatment of anterior corneal scarring by eliminating or reducing corneal opacities.

关键词： corneal scar phototherapeutic keratectomy fourier-domain optical coherence tomography corneal opacity corneal topographic indices

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微量叶尖喷气对压气机稳定性的影响

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南京航空航天大学学报 2012年第5期44卷 734-740页

作者：胡骏李亮南京航空航天大学能源与动力学院南京210016

为了研究微量喷气对压气机稳定性的影响及其机理,在双级低速轴流压气机试验器上开展了微量叶尖喷气对压气机稳定裕度影响的参数化研究,并将其结果与无喷射时的基准值进行比较。结果表明,微量喷气能够提高压气机的稳定裕度,扩宽压气机的... 详细信息

为了研究微量喷气对压气机稳定性的影响及其机理,在双级低速轴流压气机试验器上开展了微量叶尖喷气对压气机稳定裕度影响的参数化研究,并将其结果与无喷射时的基准值进行比较。结果表明,微量喷气能够提高压气机的稳定裕度,扩宽压气机的稳定工作范围,扩稳机制是抑制了模态波向旋转失速团的发展并同时改善了转子叶尖的流场;喷气量越大,微量喷气扩稳效果越明显;在相同喷气量的情况下,沿逆压气机旋转方向偏转一定的角度喷气时叶尖微量喷气具有较好的扩稳效果。

关键词：压气机微量喷气参数化研究稳定裕度

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Combination of serum gamma-glutamyltransferase and alkaline phosphatase in predicting the diagnosis of asymptomatic choledocholithiasis secondary to cholecystolithiasis

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World Journal of Clinical Cases 2019年第2期7卷 137-144页

作者： Yong Mei Li Chen Peng-Fei Zeng Ci-jun Peng jun Wang Wen-Ping Li Chao Du Kun Xiong Kai Leng Chun-Lin Feng Ji-hu Jia Department of Hepatopancreatobiliary Surgery the Third Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Diagnostics Laboratory Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Hepatopancreatobiliary Surgery Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Gamma-glutamyltransferase(GGT) is one of the most important laboratory tests for the evaluation of liver damage. Through a long-term clinical observation of patients with secondary asymptomatic choledocholithiasis, we found that most patients had abnormal GGT serum *** To investigate the combination of serum GGT and alkaline phosphatase(ALP) in predicting the diagnosis of asymptomatic choledocholithiasis secondary to *** In this retrospective cohort study, the clinical data of 829 patients with cholecystolithiasis admitted to the Third Affiliated Hospital of Zunyi Medical College from August 2014 to August 2017 were collected. Among these patients,151 patients had secondary asymptomatic choledocholithiasis and served as the observation group, and the remaining 678 cholecystolithiasis patients served as the control group. Serum liver function indexes were detected in both groups,and the receiver operating characteristic(commonly known as ROC) curves were constructed for markers showing statistical significances. The cutoff value,sensitivity, and specificity of each marker were calculated according to the ROC *** The overall incidence of asymptomatic choledocholithiasis secondary to cholecystolithiasis was 18.2%. The results of liver function indexes including serum aspartate aminotransferase, alanine aminotransferase, direct bilirubin and total bilirubin levels showed no significant differences between the two groups(P> 0.05). However, the serum GGT and ALP levels were significantly higher in the observation group than in the control group(P < 0.05). The ROC curve analysis showed that the area under the curve was 0.881(95%CI: 0.830-0.932), 0.647(95%CI: 0.583-0.711) and 0.923(0.892-0.953) for GGT, ALP, and GGT + ALP,respectively. The corresponding cut-off values of GGT and ALP were 95.5 U/L and 151.5 U/L, sensitivity were 90.8% and 65.1%, and specificity were 83.6% and59.8%, respectively. The sensitivity and specifi

关键词： Asymptomatic choledocholithiasis Gamma-glutamyltransferase Cholecystolithiasis Alkaline phosphatase Diagnosis Screening

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Potential oxidative stress in children with chronic constipation

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World Journal of Gastroenterology 2005年第3期11卷 368-371页

作者： jun-FuZhou jian-GuoLou Sheng-LiZhou Ji-YueWang SecondHospital CollegeofMedicineZhejiangUniversityHangzhou310009ZhejiangProvinceChina Children'sHospital CollegeofMedicineZhejiangUniversityHangzhou310003ZhejiangProvinceChina

AIM: To investigate the potential oxidative stress in children with -chronic constipation and to explore its ***: Seventy children with chronic constipation and 70 age- and sex-matched healthy children were enrolled in a randomized controlled study. Plasma levels of vitamins C and E, activities of superoxide dismutase and catalase and lipoperoxide level in erythrocytes were determined by ***: Compared with healthy children whose vitamin C,vitamin E, superoxide dismutase, catalase and lipoperoxide were 58.35±14.42 μmol/L, 27.15±6.55 μmol/L, 2 206±171U/(g· Hb), 327.3±82.2 K/(g·Hb) and 19.18±4.27 nmol/(g·Hb)respectively, the levels of vitamin C, vitamin E, the activity of superoxide dismutase, and catalase in the children with chronic constipation significantly decreased [46.59±11.51 μmol/L,20.65±4.80 μmol/L, 1943±147 U/(g·Hb) and 269.3±67.8 K/(g·Hb),respectively P＜0.01], while the lipoperoxide significantly increased [25.22±5.01 nmol/(g·Hb), P＜0.01]. With a prolonged course of disease, the levels of vitamin C, vitamin E, the activity of superoxide dismutase and catalase in the children with chronic constipation gradually decreased,while the level of lipoperoxide gradually ***: Chronic constipation can cause potential oxidative stress in children.

关键词： Chronic constipation Potential oxidative stress Spectrophotometry

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Apply GPCA to Motion Segmentation

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Journal of Intelligent Learning Systems and Applications 2011年第1期3卷 45-54页

作者： Hongchuan Yu jian jun Zhang 不详

In this paper, we present a motion segmentation approach based on the subspace segmentation technique, the genera-lized PCA. By incorporating the cues from the neighborhood of intensity edges of images, motion segmentation is solved under an algebra framework. Our main contribution is to propose a post-processing procedure, which can detect the boundaries of motion layers and further determine the layer ordering. Test results on real imagery have confirmed the validity of our method.

关键词： Generalized PCA Motion Segmentation Layer Ordering

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Thickness-dependent morphologies of Ag on n-layer MoS2 and its surface-enhanced Raman scattering

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Nano Research 2016年第6期9卷 1682-1688页

作者： Ya Deng Minjiang Chen jian Zhang Zihao Wang Wenbin huang Yun Zhao Jean PierreNshimiyimana Xiao hu Xiannian Chi Gu Hou ,Xueyao Zhang Yanjun Guo Lianfeng Sun CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology 8eijing 100190 China School of Physics Shandong University Jinan 250100 China Chinese Academy of Sciences Beijing 100049 China

The size and density of Ag nanoparticles on n-layer MoS2 exhibit thickness- dependent behavior. The size and density of these particles increased and decreased, respectively, with increasing layer number （n） of n-layer MoS2. Furthermore, the surface-enhanced Raman scattering （SERS） of Ag on this substrate was observed. The enhancement factor of this scattering varied with the thickness of MoS2. The mechanisms governing the aforementioned thickness dependences are proposed and discussed.

关键词： MoS2 nanoparticle thickness-dependent surface-enhanced Ramanscattering (SERS)

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Combining surgery with 125I brachytherapy for recurrent mediastinal dedifferentiated liposarcoma: A case report and review of literature

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World Journal of Clinical Cases 2020年第5期8卷 939-945页

作者： hui-Guo Chen Kai Zhang Wei-Bin Wu Yong-hui Wu jian Zhang Li-Jia Gu Xiao-jun Li Department of Cardiothoracic Surgery the Third Affiliated Hospital of Sun Yat-sen University

BACKGROUND Dedifferentiated liposarcoma in the mediastinum is an extremely rare malignant neoplasm.A few previous case reports indicate that surgical resection is the major treatment,but frequent recurrence occurs *** to its rarity,its clinical characteristics,optimal treatment and clinical outcomes remain ***,we report a case of multifocal recurrent dedifferentiated liposarcoma in the posterior mediastinum treated by combining surgery with 125I brachytherapy,and summarize its clinical features,treatment and *** SUMMARY A 75-year-old man was admitted to our hospital with a history of gradual dysphagia for one year and aggravated dysphagia for 3 ***-enhanced computed tomography(CT)revealed several large cystic-solid masses with lipomatous density,and calcification in the posterior-inferior *** patient received a wide excision by video-assisted thoracoscopic *** analysis confirmed the tumors were dedifferentiated *** tumor locally relapsed 24 mo later,and another operation was performed by video-assisted thoracoscopic *** months after the second surgery,the tumor recurred again,and the patient received CT-guided radioactive seeds 125I *** 8 mo,follow-up chest CT showed an enlarged ***,his condition exacerbated with severe dysphagia and dyspnea,and he died of respiratory failure in July *** We reviewed the literature,and suggest that surgical resection provides beneficial effects for dedifferentiated liposarcoma in the mediastinum,even in cases with local recurrence.125I brachytherapy may be beneficial for recurrent unresectable patients.

关键词： Dedifferentiated liposarcoma Mediastinal neoplasms Recurrence Reoperation 125I brachytherapy Case report

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大直径杯型冻土壁温度场数值分析

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岩土力学 2015年第2期36卷 523-531页

作者：胡俊杨平南京林业大学土木工程学院江苏南京210037 海南大学土木建筑工程学院海南海口570228

结合南京地铁10号线过江隧道盾构始发工程,运用有限元软件建立三维数值模型,对大直径杯型冻土壁温度场的发展与分布规律进行研究,分析不同因素对该温度场的影响规律,比较研究不同土层下该温度场的降温规律。数值计算表明:在设计冻结方案... 详细信息

结合南京地铁10号线过江隧道盾构始发工程,运用有限元软件建立三维数值模型,对大直径杯型冻土壁温度场的发展与分布规律进行研究,分析不同因素对该温度场的影响规律,比较研究不同土层下该温度场的降温规律。数值计算表明:在设计冻结方案下,杯型冻土帷幕厚度满足加固范围要求,开始交圈时间由早到迟依次为外圈管>中圈管>内圈管,形成闭合大直径杯型冻结帷幕的时间为12 d;冻结壁交圈时间随导热系数的增大而线性减小,随容积热容量和原始地温的增大而线性增大,原始地温每升高5℃,冻结壁交圈时间增加约1 d;相变潜热变化对冻结初期和后期土体降温过程几乎没有影响;不同土层降温速度由快到慢分别为砂土水泥土>黏土水泥土,砂土>黏土;砂土水泥土与砂土、黏土水泥土与黏土几乎同时达到相变阶段;无论水泥改良与否,砂土总比黏土的开始交圈时间早4 d。所得结果为今后类似工程设计提供了理论依据。

关键词：大直径杯型冻土壁盾构始发温度场数值模拟

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Technological conditions for purification of hafnium by iodide process

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Rare Metals 2020年第2期39卷 200-204页

作者： Li-Sen Tian Yan-Xi Yin Zhi-Fang hu Hong-Lin jiang Zhong-Qi Li Li-jun Wang Division of Rare Metals Materials&Metallurgy General Research Institute for Nonferrous MetalsBeijing100088China

In nuclear industry,the purity of hafnium control rod is usually significant,and the process parameters will affect the impurity *** this study,the four key factors(filament temperature,retort materials,feeds,and iodide reaction time)were *** is found that the impurity contents of Fe,Ni in the hafnium crystal bar decrease with the K value *** the retort materials and feed types have obvious influence on the impurity contents of hafnium crystal *** iodide reaction time has little effect on the impurity contents of hafnium crystal bar.

关键词： Hafnium Purity K value Iodide

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Short-term entecavir therapy of chronic severe hepatitis B

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Hepatobiliary & Pancreatic Diseases International 2009年第3期8卷 261-266页

作者： Chen, jun Han, jian-hua Liu, Chun Yu, Ren-He Li, Fa-Zhao Li, Qun-Fang Gong, Guo-Zhong Cent S Univ Liver Dis Ctr Xiangya Hosp 2 Changsha 410011 Peoples R China Cent S Univ Sch Publ Hlth Dept Epidem & Hlth Stat Changsha 410078 Peoples R China

BACKGROUND: Chronic severe hepatitis B patients often have limited survival. This investigation aimed to evaluate the short-term effects of nucleoside analog therapy on chronic severe hepatitis B. METHODS: We retrospectively, randomly collected the data of 129 chronic severe hepatitis B patients: 55 were treated with entecavir, and the remaining 74 were not treated with nucleoside analogues. RESULTS: No significant difference in short-term survival rate was found between the group treated with entecavir and that treated without nucleoside analogues. Although entecavir greatly reduced HBV replication in different periods of therapy (P10(4) to = 10(6) copies/ml). Nor correlation was observed between HBV DNA levels and MELD scores in different periods of therapy (P>0.05). The HBV DNA levels of patients who survived for over 3 months or less than 3 months were not significantly different either. However, the MELD score and parameters of liver function (albumin, bilirubin, prothrombin time) were different between the two groups (P<0.05). CONCLUSION: These results suggest that short-term suppression of HBV replication may not slow down the progression of liver failure in patients with chronic severe hepatitis B.

关键词： chronic severe hepatitis mortality entecavir

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