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Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications

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Rare Metals 2024年第7期43卷 2968-2993页

作者： jian-Bin zhang Nan Zhou Li-Hui zhang Cong-Hui Shang Jia-Xuan Li Yi Zhao Guo-Hui Jia Ru-Sen Yang hua Xu Xiao-Bo Li Shaanxi Joint Key Laboratory of Graphene Shaanxi Key Laboratory of High-Orbits-Electron Materials and Protection Technology for AerospaceShaanxi Joint Key Laboratory of GrapheneSchool of Advanced Materials and NanotechnologyXidian UniversityXi'an710126China Guangzhou Institute of Technology Xidian UniversityGuangzhou 710068China Xi'an Thermal Power Research Institute Co. LtdXi'an 710054China Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationShaanxi Key Laboratory for Advanced Energy DevicesShaanxi Engineering Lab for Advanced Energy TechnologySchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an Xi'an 710119China

Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial,spectral and polarized ***,low-dimensional anisotropic materials with inherent anisotropic properties,ultrathin thickness,tunable bandgap and feasible integration with complementary metal oxide semiconductor(CMOS)fabrication processes have attracted great interest for their facilitation of polarized photodetector devices *** the polarized detection performance of low-dimensional materials to satisfy realistic needs stimulates the exploration of modulation of anisotropic *** this review,we comprehensively introduce the latest research progress in modulating the optical and optoelectronic anisotropy characteristics of low-dimensional *** strategy of anisotropy regulation through crystal structure engineering and coupling system is discussed ***,the latest progress in image recognition applications using anisotropic low-dimensional materials is reviewed in ***,we summarize the challenge and propose future opportunities in the practical application of polarized-sensitive imaging photodetectors based on low-dimensional anisotropic materials.

关键词： Anisotropy Polarized detection Image recognition Low-dimensional materials

维普期刊数据库

Efficient Contact between H_(2)O and N-Coordinate Ru Nanoparticles in Three-Dimensionally Ordered Macro/Mesoporous Carbon Boosting Alkaline HER

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Chinese Journal of Chemistry 2024年第2期42卷 164-170页

作者： Jiaqing Luo Chunyu Liu Ruolin zhang Yuanqing Sun hua Xu Qingying Hu Manxue zhang Jun Li Zhenxing Li Weiyu Song Yuechang Wei jian Liu State Key Laboratory of Heavy Oil and Bejing Key Lab of Oil&Gas Optical Detection Technology China University of PetroleumBeijing 102249China Laboratory of Heavy Oil at Karamay Ching University of Petroleum-Beijing at KaramayKaramayXinjiang 83400China Basic Research Center for Energy Interdisciplinary College of ScienceChina University of PetroleumBeijing 102249China Petrochemical Research Institute PetroChina Company LimitedBeijing 102206China BeijingNationalLaboratoryfor Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China

In this study,a novel approach is proposed to achieve the uniformly dispersed Ru nanoparticles with N coordination loaded on three-dimensionally ordered macro/mesoporous carbon(3DOMMC)through simultaneous pyrolysis of Ru^(3+)and cyanamide on *** an alkaline medium,the synthesized catalysts exhibit exceptional hydrogen evolution reaction(HER)***,Ru-N/3DOMMC demonstrates a significantly low overpotential of 13.8 mV to achieve acrent density of 10 *** exhibits a mass activity 17.5 times higher than that of commercial Pt/*** outstanding performance could be attributed to the ultrahigh Ru dispersion and more efficient contact between active sites and reactant,which derived from the large specific surface area and interconnective three-dimensionally macro/mesopores of 3DOMMC.

关键词： 3DOMMC Hydrogen evolution reaction Electrocatalysis Solid-liquid contact Energy conversion

Association between glucose-lowering drugs and circulating insulin antibodies induced by insulin therapy in patients with type 2 diabetes

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World Journal of Diabetes 2024年第7期15卷 1489-1498页

作者： Peng zhang Qing jiang Bo Ding Reng-Na Yan Yun Hu jian-hua Ma Department of Endocrinology Nanjing First HospitalNanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina Department of Endocrinology The Affiliated Wuxi People's Hospital of Nanjing Medical UniversityWuxi Medical CenterWuxi 214000Jiangsu ProvinceChina

BACKGROUND Insulin antibodies(IAs)affect blood glucose control in patients receiving insulin *** To investigate the relationship between different hypoglycemic treatments and IAs in patients with type 2 diabetes mellitus(T2DM).METHODS This cross-sectional,retrospective study included 1863 patients with T2DM who were receiving exogenous insulin *** patients received stable antidiabetic therapy in the last 3 months and IA levels were measured using an iodine-125 *** A total of 1863 patients were *** were 902(48.4%)patients who had positive IAs(IA level>5%),with a mean IA level of 11.06%(10.39%-11.72%).IA levels were positively correlated with high fasting blood glucose(odds ratio=1.069,P<0.001).The proportion of positive IAs was lowest in patients using glargine only(31.9%)and highest in patients using human insulin only(70.3%),P<*** IA levels in patients using sulfonylureas/glinides(8.3%),metformin(9.6%),and dipeptidyl peptidase-4 inhibitors(8.2%)were all lower than in patients without these drugs(all P<0.05).CONCLUSION Nearly half of patients on insulin therapy have positive IA antibodies,and IA antibody levels are associated with blood glucose *** glargine and a combination of oral glucose-lowering drugs were correlated with lower IA levels.

关键词： Insulin antibodies Insulin therapy Glucose-lowering drugs Glargine Type 2 diabetes

Microstructure-ionisation potential relationship analysis for understanding the molecular ionisation difference of natural esters during the impulse discharge via DFT calculation

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High Voltage 2024年第4期9卷 920-929页

作者： Jingwen zhang jian Hao Wenyu Ye Junyi zhang Ruijin Liao State Key Laboratory of Power Transmission Equipment Technology School of Electrical/EngineeringChongqing UniversityChongqingChina

Understanding the impulse discharge behaviour of natural ester(NE)is crucial for its safe application in high-voltage *** ionisation potential(IP)of triglycerides plays a significant role in the process of molecular ionisation during impulse discharge for *** correlation coefficients between molecular size,frontier orbital,electrostatic potential,polarity,and IP were *** the quantitative microstructure-IP model for triglycerides were built,which revealed that IP is strongly related to the highest occupied molecular orbital(HOMO)energy EHM,as well as the average value of positive electrostatic potential V_(p)(t),the average value of negative electrostatic potential V_(p)(-),and the surface area of negative electrostatic potential S(-).The HOMO and negative electrostatic potentials of saturated triglycerides are predominantly linked to the carbonyl O ***,in unsaturated triglycerides,the influence of C=C double bonds on HOMO and negative electrostatic potentials is more ***,the IP of unsaturated NE with C=C bonds is lower than that of saturated NE,rendering it more susceptible to ionisation under a strong electric field which is unfavourable for impulse breakdown *** structure-property correlation analysis is valuable for understanding ionisation mechanism during the impulse discharge breakdown of NE at the microscopic level.

关键词： electrostatic potential bonds

Surface-phonon-polariton-enhanced photoinduced dipole force for nanoscale infrared imaging

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National Science Review 2024年第5期11卷 227-235页

作者： jian Li Junghoon Jahng Xuezhi Ma Jing Liang Xue zhang Qianhao Min Xiao-Liang Wang Shuangjun Chen Eun Seong Lee Xing-hua Xia State Key Lab of Analytical Chemistry for Life Science School of Chemistry and Chemical Engineering Nanjing University Hyperspectral Nano-Imaging Team Korea Research Institute of Standards and Science Institute of Materials Research and Engineering Agency for ScienceTechnology and Research College of Materials Science and Engineering Nanjing Tech University

The photoinduced dipole force(Pi DF) is an attractive force arising from the Coulombic interaction between the light-induced dipoles on the illuminated tip and the sample. It shows extreme sample-tip distance and refractive index dependence, which is promising for nanoscale infrared(IR) imaging of ultrathin samples. However, the existence of Pi DF in the mid-IR region has not been experimentally demonstrated due to the coexistence of photoinduced thermal force(Pi TF), typically one to two orders of magnitude higher than Pi DF. In this study, we demonstrate that, with the assistance of surface phonon polaritons, the Pi DF of c-quartz can be enhanced to surpass its Pi TF, enabling a clear observation of Pi DF spectra reflecting the properties of the real part of permittivity. Leveraging the detection of the Pi DF of phonon polaritonic substrate, we propose a strategy to enhance the sensitivity and contrast of photoinduced force responses in transmission images, facilitating the precise differentiation of the heterogeneous distribution of ultrathin samples.

关键词： surface phonon polariton photoinduced dipole force nanoscale infrared imaging ultrathin sample

The Research Progress of Bioinformatics-Led Design of Single-Chain Antibody Molecules

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The Research Progress of Bioinformatics-Led Design of Single...

Recent advances in ocular lubrication

The 2011 International Conference on Information Technology and Agricultural Engineering(ICITAE 2011)

作者： Guo-Yong Shan jian-hua zhang Department of Radiation Oncology Zhengzhou People's Hospital The Faculty of Biomedical Engineering Zhengzhou University

The development of single-chain antibody（scF v） by recombinant gene expression is an important milestone for cancer gene therapy. Single-chain antibodies are reconstructed for cancer-targeted therapy to provide good penetration into tumor tissue and to improve their pharmacokinetics in vivo, offering a clinically valuable application. However, there may be some variation between the structure and function of the fusion proteins. Analyzing the interaction region between the antibody and the antigen, and the binding sites for molecular conformation, it is clear that the existing antibodies need to be modified, enhancing the biological activity of the antibodies. Based on the view that bio-molecular computer models are closely integrated with biological experiments, a bio-molecular structure–activity relationship model can be established in terms of molecular conformation, physical and chemical properties and the biological activity of single-chain antibodies. On the one hand, the structure–activity relationship is clear for new immune molecules at the gene expression level. On the other hand, a single-chain antibody molecule can be designed and optimized for the cancer-oriented treatment. In this review, we provide the theoretical and experimental basis for the development of singlechain antibodies appropriate for cancer therapy.

关键词： Single-chain antibody Fusion genes Bioinformatics Structure– activity relationship

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Friction 2024年第9期12卷 1929-1954页

作者： jianhua zhang Yunjuan SU jian WU Hongdong WANG School of Mechatronic Engineering and Automation and Key Laboratory of Advanced Display and System Application Ministry of EducationShanghai UniversityShanghai 200444China

The ocular lubrication,where the eyelid constantly slides on the curved corneal surface,is considered as one of primary lubrication systems in *** reliable lubrication conditions,sensitive ocular tissues remain intact from fatigue damage during spontaneous blink *** tear film,evenly filled between cornea and conjunctiva,is a biological fluid with dynamic adjustment ability,which provides superior lubrication with the friction coefficient of below ***,the lubrication failure may result in a variety of uncomfortable symptoms such as inflammatory reactions,tissue damage and neurological ***,it is essential to clarify the fundamental mechanism of ocular lubrication,which helps to alleviate and even recover from various ocular *** review firstly demonstrates that the ocular components,containing lipids and mucins,contribute to maintaining the lubrication stability of tear ***,the ocular lubrication state in various physiological environments and the physical effect on tear film dynamics are further *** typical applications,the therapeutic agents of dry eye syndrome and contact lens with superior lubrication effects are introduced and their lubrication mechanisms are ***,this review summarizes a series of the latest research inspired by ocular ***,this work will provide a valuable guidance on the theoretical research and extensive applications in the field of biological lubrication.

关键词： bio-tribology ocular lubrication tear film dry eye syndrome tear film dynamics

Prediction of lime utilization ratio of dephosphorization in BOF steelmaking based on online sequential extreme learning machine with forgetting mechanism

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International Journal of Minerals,Metallurgy and Materials 2024年第3期31卷 508-517页

作者： Runhao zhang jian Yang Han Sun Wenkui Yang State Key Laboratory of Advanced Special Steel School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

The machine learning models of multiple linear regression(MLR),support vector regression(SVR),and extreme learning ma-chine(ELM)and the proposed ELM models of online sequential ELM(OS-ELM)and OS-ELM with forgetting mechanism(FOS-ELM)are applied in the prediction of the lime utilization ratio of dephosphorization in the basic oxygen furnace steelmaking *** ELM model exhibites the best performance compared with the models of MLR and ***-ELM and FOS-ELM are applied for sequential learning and model *** optimal number of samples in validity term of the FOS-ELM model is determined to be 1500,with the smallest population mean absolute relative error(MARE)value of 0.058226 for the *** variable importance analysis reveals lime weight,initial P content,and hot metal weight as the most important variables for the lime utilization *** lime utilization ratio increases with the decrease in lime weight and the increases in the initial P content and hot metal weight.A prediction system based on FOS-ELM is applied in actual industrial production for one *** hit ratios of the predicted lime utilization ratio in the error ranges of±1%,±3%,and±5%are 61.16%,90.63%,and 94.11%,*** coefficient of determination,MARE,and root mean square error are 0.8670,0.06823,and 1.4265,*** system exhibits desirable performance for applications in actual industrial pro-duction.

关键词： basic oxygen furnace steelmaking machine learning lime utilization ratio dephosphorization online sequential extreme learning machine forgetting mechanism

维普期刊数据库

METTL5 promotes gastric cancer progression via sphingomyelin metabolism

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1925-1946页

作者： Ya-Qiong zhang jian Li Zhe Qin De-Ming Li Fang-Zhou Ye Song-hua Bei Xiao-Hong zhang Li Feng Endoscopy Center Minhang Hospital Affiliated to Fudan UniversityShanghai 201100China

BACKGROUND The treatment of gastric cancer(GC)has caused an enormous social burden *** studies have reported that N6-methyladenosine(m6A)is closely related to tumor ***5 is a m6A methyltransferase that plays a pivotal role in maintaining the metabolic stability of ***,its aberrant regulation in GC has not been fully *** To excavate the role of METTL5 in the development of *** METTL5 expression and clinicopathological characteristics were analyzed via The Cancer Genome Atlas dataset and further verified via immunohistochemistry,western blotting and real-time quantitative polymerase chain reaction in tissue microarrays and clinical *** tumor-promoting effect of METTL5 on HGC-27 and AGS cells was explored in vitro by Cell Counting Kit-8 assays,colony formation assays,scratch healing assays,transwell assays and flow *** tumor-promoting role of METTL5 in vivo was evaluated in a xenograft tumor *** EpiQuik m6A RNA Methylation Quantification Kit was used for m6A ***,liquid chromatography-mass spectrometry was used to evaluate the association between METTL5 and sphingomyelin metabolism,which was confirmed by Enzyme-linked immunosorbent assay and rescue *** addition,we investigated whether METTL5 affects the sensitivity of GC cells to cisplatin via colony formation and transwell *** Our research revealed substantial upregulation of METTL5,which suggested a poor prognosis of GC *** METTL5 expression indicated distant lymph node metastasis,advanced cancer stage and pathological *** increased level of METTL5 correlated with a high degree of m6A ***5 markedly promotes the proliferation,migration,and invasion of GC cells in ***5 also promotes the growth of GC in animal ***5 knockdown resulted in significant changes in sphingomyelin metabolism,which implies that METTL5 may impact the development of GC via sphin

关键词： Gastric cancer METTL5 Sphingomyelin metabolism Cisplatin