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Synthesis of novel aromatic polyimides containing bulky side chain for vertical alignment liquid crystals

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Chinese Chemical Letters 2008年第3期19卷 359-362页

作者： jian wang Ying Han wang State Key Laboratory of Polymer Materials Engineering of China College of Polymer Science and Engineering Sichuan University Chengdu 610065 China

In this study, a novel 4-（4-octyloxybenzoyloxy）biphenyl-3′,5′-diaminobenzoate and polyimides based on it were synthesized. The polyimide with mesogenic unit side chain exhibited excellent vertical alignment for nematic liquid crystal （LC）. The pretilt angles of LCs above 89° were kept after the rubbing process with 220 mm rubbing strength. The polyimide films as the alignment layer were baked at 120℃ for 12 h, the vertical alignment of LCs was still uniform and stable. Meanwhile, the UV-vis spectra of the noyel polyimide films showed the high transparency in a visible wave length.

关键词： Polyimide Liquid crystal Vertical alignment

Illuminating Neural Circuits in Alzheimer’s Disease

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Neuroscience Bulletin 2021年第8期37卷 1203-1217页

作者： Yang Ying jian-Zhi wang Department of Pathophysiology School of Basic MedicineMinistry of Education Key Laboratory for Neurological DisordersHubei Key Laboratory for Neurological DisordersTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Alzheimer’s disease(AD)is the most common neurodegenerative disorder and there is currently no *** circuit dysfunction is the fundamental mechanism underlying the learning and memory deficits in patients with ***,it is important to understand the structural features and mechanisms underlying the deregulated circuits during AD progression,by which new tools for intervention can be ***,we briefly summarize the most recently established cutting-edge experimental approaches and key techniques that enable neural circuit tracing and manipulation of their *** also discuss the advantages and limitations of these ***,we review the applications of these techniques in the discovery of circuit mechanisms underlyingβ-amyloid and tau pathologies during AD progression,and as well as the strategies for targeted AD treatments.

关键词： Neural circuit Alzheimer’s disease Single cell RNA sequencing Neural circuit tracing Optogenetics Chemogenetics

Progress and challenges in the cardiovascular field

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第8期13卷 587-588页

作者： jian-an wang Department of Cardiology the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China Cardiovascular Key Lab of Zhejiang Province the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China

Despite great achievements in their treatment and prevention in the past few decades,cardiovascular diseases remain the leading cause of human mortality and morbidity all around the *** estimated by the world health organization (WHO) in 2008,over 17 million people die from cardiovascular diseases every *** is reported that in China we have around 23 million cardiovascular disease patients,along with a significant disease burden (Zhao and Liu,2012).

关键词：心血管疾病世界卫生组织生物医学医疗机构非营利性商业机构信息技术医学领域

A universal method to calculate the surface energy density of spherical surfaces in crystals

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Acta Mechanica Sinica 2017年第1期33卷 77-82页

作者： jian wang jianjun Bian Xinrui Niu Gangfeng wang Department of Engineering Mechanics SVL Xi’an Jiaotong University CASM and Department of Mechanical and Biomedical Engineering City University of Hong Kong

Surface energy plays an important role in the mechanical performance of nanomaterials; however, determining the surface energy density of curved surfaces remains a challenge. In this paper, we conduct atomic simulations to calculate the surface energy density of spherical surfaces in various crystalline metals. It is found that the average surface energy density of spherical surfaces remains almost constant once its radius exceeds 5 nm. Then, using a geometrical analysis and the scaling law, we develop an analytical approach to estimate the surface energy density of spherical surfaces through that of planar surfaces. The theoretical prediction agrees well with the direct atomic simulations, and thus provides a simple and general method to calculate the surface energy density in crystals.

关键词： Surface energy density Nanoparticle Nanocavity

Non-uniform Gradient Estimates for SDEs with Local Monotonicity Conditions

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Acta Mathematica Sinica,English Series 2021年第3期37卷 458-470页

作者： jian wang Bing Yao WU College of Mathematics and Informatics&Fujian Key Laboratory of Mathematical Analysis and Applications(FJKLMAA)&Center for Applied Mathematics of Fujian Province(FJNU) Fujian Normal UniversityFuzhou 350007P.R.China College of Mathematics and Informatics Fujian Normal UniversityFuzhou 350007P.R.China

By using the coupling method and the localization technique, we establish non-uniform gradient estimates for Markov semigroups of diffusions or stochastic differential equations driven by pure jump Le′vy noises, wher... 详细信息

关键词： Gradient estimate Markov semigroup monotonicity condition coupling stochastic differential equation Lévy process

Removal of sulfonamide antibiotics from wastewater by gamma irradiation in presence of iron ions

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Nuclear Science and Techniques 2016年第5期27卷 104-108页

作者： Zhong Wan jian-Long wang Collaborative Innovation Center for Advanced Nuclear Energy Technology INET Tsinghua UniversityBeijing 100084 China Beijing Key Laboratory of Radioactive Waste Treatment INET Tsinghua University Beijing 100084 China

The presence of sulfonamide antibiotics in aquatic environments has received increasing attention in recent ***(SD),a widely used heterocyclic sulfonamide pharmaceutical,has entered into the receiving water *** this paper,gamma rays are used to irradiate samples of sulfadiazine antibiotics-containing *** results demonstrate that SD can be effectively degraded by irradiation,but the mineralization degree of SD(in terms of TOC) is not as efficient as the SD *** addition of Fe^(2+) can significantly enhance the SD degradation and mineralization through the generation of hydroxyl radical by catalytic decomposition of H_2O_2 from water *** chromatography analysis indicates that sulfate ions(SO_4^(2-)) and formate(HCOO^-) are the main intermediate *** irradiation is a promising technology for removing low-concentration antibiotics from water and wastewater.

关键词： γ射线照射废水样品抗生素磺胺类铁离子降解效率离子色谱分析羟基自由基

Sustainable Polyamides Enabled by Controlled Ring-opening Polymerization of 4-Hydroxyproline-derived Lactams

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Chinese Journal of Polymer Science 2023年第5期41卷 728-734,I0008页

作者： jian-Qun wang Xian-Hong wang You-Hua Tao Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China University of Science and Technology of China Hefei 230026China

Aliphatic polyamides have been considered as eco-friendly materials,useful for a wide range of ***,it still presents obstacle to produce sustainable aliphatic polyamides from abundant renewable ***,we describe that 4-hydroxyproline(4-HYP),a renewable resource,was readily converted to its corresponding bicyclic bridged lactam monomers bearing pendant Boc-protected secondary amino group,and oligo-ethylene glycol *** hexamethyldisilazide(LiHMDS)-mediated polymerization of the resulting monomers exhibited a controlled feature,affording sustainable aliphatic polyamides with number-average molecular weight up to 73 kg/mol and a low molecular weight distribution?<***,this work can lead to a novel kind of functional and sustainable polyamides with potential applications,including degradable plastics,and drug delivery.

关键词： Polyamides Renewable Ring-opening polymerization 4-Hydroxyproline

Impact of initial fluctuations and nuclear deformations in isobar collisions

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Nuclear Science and Techniques 2024年第6期35卷 155-162页

作者： jian-Fei wang Hao-Jie Xu Fu-Qiang wang Department of Modern Physics University of Science and Technology of ChinaHefei 230026China School of Science Huzhou UniversityHuzhou 313000China Strong-Coupling Physics International Research Laboratory(SPiRL) Huzhou UniversityHuzhou 313000China Department of Physics and Astronomy Purdue UniversityWest LafayetteIN 47907USA

Relativistic isobar^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zrcollisions have revealed intricate differences in their nuclear size and shape,inspiring unconventional studies of nuclear structure using relativistic heavy ion *** this study,we investigate the relative differences in the mean multiplicityR_()and the secondR_(ε2)and third-order eccentricityR_(ε3)between isobar collisions using initial state Glauber *** is found that initial fluctuations and nuclear deformations have negligible effects on R_()in most central collisions,while both are important for the R_(ε2)and R_(ε3),the degree of which is sensitive to the underlying nucleonic or sub-nucleonic degree of *** features,compared to real data,may probe the particle production mechanism and the physics underlying nuclear structure.

关键词： Relativistic isobar collisions Initial fluctuations Nuclear deformation

Thermal Resistance Simulation for CoF Packages

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Tsinghua Science and Technology 2015年第3期20卷 277-284页

作者： Chuan Chen Qian wang Xiaotian Meng Lin Tan jian wang Chengqiang Cui jian Cai the Institute of Microelectronics Tsinghua University Beijing 100084 China AKM Electronics Technology (Suzhou) Company Ltd. Suzhou 215000 China the Institute of Microelectronics and Tsinghua National Laboratory for Information Science and Technology Tsinghua University. Beijing 100084 China

Chip-on-Film （CoF） is a packaging technology that mounts Integrated Circuits （IC） chips directly on a flexible substrate surface. As both power and the number of pins in such packages increase, thermal conditions become more important. In this paper, the thermal resistance of CoF packages is studied using Ansys software to perform finite-element analysis. Because of circuit complexity, two equivalent methods-a length-weighted method and an image-recognition method--are proposed in place of an accurate model to get equivalent thermal conductivity of CoF package devices. In our experiments, the simulated value of thermal resistance based on the length-weighted method was 1.653 K/W, and the value based on the image-recognition method was 1.911 K/W. The real thermal resistance value of the CoF package device is 1.812 K/W. So the error between the real value measured by a tester and the simulated value based on the length-weighted method is 8.8%, and the error between the real value and the simulated value based on the image-recognition method is 5.5%. Hence, both methods can provide effective simulation results, and the image-recognition method is more accurate. In addition, we optimized the CoF package structure. From the simulation results, the drop in thermal resistance after the optimization is obvious.

关键词： Chip-on-Film (CoF) finite element analysis equivalent thermal conductivity