检索结果-南通市图书馆

Long-term outcomes and prognostic factors for patients with esophageal cancer following radiotherapy

World Journal of Gastroenterology 2013年第10期19卷 1639-1644页

作者： Chuang-Zhen chen jian-zhou chen De-Rui Li Zhi-Xiong Lin Ming-Zhen zhou Dong-Sheng Li Zhi-jian chen Department of Radiation Oncology Cancer Hospital of Shantou University Medical College

AIM:To evaluate long-term outcomes and prognostic factors for esophageal squamous cell carcinoma(SCC) treated with three dimensional conformal radiotherapy(3D-CRT).METHODS:Between January 2005 and December 2006,153 patients(120 males,33 females) with pathologically confirmed esophageal SCC and treated with 3D-CRT in Cancer Hospital of Shantou University were included in this retrospective *** age was 60 years(range:37-84 years).The proportion of tumor location was as follows:upper thorax(including the cervical region),73(48%);middle thorax,73(48%);lower thorax,7(5%),*** median radiation dose was 64 Gy(range:50-74 Gy).Fifty four cases(35%) received cisplatin-based concurrent *** and multivariate analysis were performed to determine the association between the correlative factors and ***:The five-year overall survival rate was 26.3%,with a median follow-up of 49 mo(range:3-66 mo) for patients who were still *** univariate analysis,lesion location,lesion length by barium esophagogram,computed tomography imaging characteristics including Y diameter(anterior-posterior,AP,extent of tumor),gross tumor volume of primary lesion(GTV-E),volume of positive lymph nodes(GTV-LN),and the total target volume(GTV-T = GTV-E + GTVLN) were prognostic for overall *** multivariate analysis,only the Y diameter [hazard ratio(HR) 2.219,95%CI 1.141-4.316,P = 0.019] and the GTV-T(HR 1.372,95%CI 1.044-1.803,P = 0.023) were independent prognostic factors for ***:The overall survival of esophageal carcinoma patients undergoing 3D-CRT was *** best predictors for survival were GTV-T and Y diameter.

关键词： Esophageal neoplasm Three dimensional conformal radiotherapy Multivariate analysis Prognostic factor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current recognition and management of intra-abdominal hypertension and abdominal compartment syndrome among tertiary Chinese intensive care physicians

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第2期12卷 156-162页

作者： jian-cang zhou Hong-chen ZHAO Kong-han PAN Qiu-ping XU Department of Critical Care Medicine Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou 310016 China

This survey was designed to clarify the current understanding and clinical management of intra-abdominal hypertension （IAH）/abdominal compartment syndrome （ACS） among intensive care physicians in tertiary Chinese hospitals. A postal twenty-question questionnaire was sent to 141 physicians in different intensive care units （ICUs）. A total of 108 （76.6%） questionnaires were returned. Among these, three quarters worked in combined medical-surgical ICUs and nearly 80% had primary training in internal or emergency medicine. Average ICU beds, annual admission, ICU length of stay, acute physiology and chronic health evaluation （APACHE）II score, and mortality were 18.2 beds, 764.5 cases, 8.3 d, 19.4, and 21.1%, respectively. Of the respondents, 30.6% never measured intra-abdominal pressure （IAP）. Although the vast majority of the ICUs adopted the exclusively transvesicular method, the over- whelming majority （88.0%） only measured lAP when there was a clinical suspicion of IAH/ACS and only 29.3% measured either often or routinely. Moreover, 84.0% used the wrong priming saline volume while 88.0% zeroed at reference points which were not in consistence with the standard method for lAP monitoring recommended by the World Society of Abdominal Compartment Syndrome. ACS was suspected mainly when there was a distended ab- domen （92%）, worsening oliguria （80%）, and increased ventilatory support requirement （68%）. Common causes for IAH/ACS were ＂third-spacing from massive volume resuscitation in different settings＂（88%）, ＂intra-abdominal bleeding＂, and ＂liver failure with ascites＂（52% for both）. Though 60% respondents would recommend surgical decompression when the lAP exceeded 25 mmHg, accompanied by signs of organ dysfunction, nearly three quarters of re- spondents preferred diuresis and dialysis. A total of 68% of respondents would recommend paracentesis in the treatment for ACS. In conclusion, urgent systematic education is absolutely necessary for most intensive care physician

关键词： Questionnaire Intra-abdominal pressure Intra-abdominal hypertension Decompression laparotomy Abdominal compartment syndrome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simultaneous modulated accelerated radiation therapy for esophageal cancer:A feasibility study

引用

World Journal of Gastroenterology 2014年第38期20卷 13973-13980页

作者： Wu-Zhe Zhang jian-zhou chen De-Rui Li Zhi-jian chen Hong Guo Ting-Ting Zhuang Dong-Sheng Li Ming-Zhen zhou Chuang-Zhen chen Department of Radiation Oncology Cancer Hospital of Shantou University Medical College

AIM: To establish the feasibility of simultaneous modulated accelerated radiation therapy (SMART) in esophageal cancer (EC).

关键词： Simultaneous modulated accelerated radiation therapy Three-dimensional conformal radiotherapy Intensity-modulated radiation therapy Esophageal cancer Feasibility

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Positions and Spectral Energy Distributions of 41 Star Clusters in M33

引用

Chinese Journal of Astronomy and Astrophysics 2002年第3期2卷 197-206页

作者： Jun Ma, Xu zhou, jian-Sheng chen, Hong Wu, Zhao-Ji jiang, Sui-jian Xue and Jin ZhuNational Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 National Astronomical Observatories Chinese Academy of Sciences Beijing 100012

We present accurate positions and multi-color photometry for 41 star clusters detected by Melnick & D'odorico in the nearby spiral galaxy M33 as a part of the BATC Color Survey of the sky in 13 intermediate-band filters from 3800 to 10 000 A. The coordinates of the clusters are found from the HST Guide Star Catalog. By aperture photometry, we obtain the spectral energy distributions of the clusters. Using the relations between the BATC intermediate-band system and UBVRI broadband system, we derive their V magnitudes and B - V colors and find that most of them are blue, which is consistent with previous findings.

关键词： galaxies: individual (M33) - galaxies: evolution - galaxies: star clusters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis of poly（lactide-co-glycolide） with high viscosity-average molecular weight

引用

Journal of Chemistry and Chemical Engineering 2009年第4期3卷 18-25页

作者： FAN Xin chen jian RUAN jian-ming zhou Zhong-chen ZOU jian-peng State Key Laboratory of Powder Metallurgy Central South University Changsha 410083 China

In the present paper, poly（lactide-co-glycolide）（PLGA） with high viscosity-average molecular weight was fabricated with L-lactide （LLA） and glycolide （GA） as monomers via opening-ring polymerization. Fourier transform Infrared （FTIR） spectroscopy, ~H-NMR, X-ray diffraction （XRD） and scanning electron microscopy （SEM） were applied to characterize the products. Viscosity method was used to determine the viscosity-average molecular weight of the PLGA copolymers. Moreover, the mechanical strength of PLGA was investigated. The results showed that the highly pure LLA and GA were prepared. The as-fabricated PLGA was typical semicrystalline copolymer with the crystallinity of 18.72%. Both viscosity-average molecular weight and mechanical strength of PLGA decreased gradually with the increase of GA content. In addition, the higher the viscosity-average molecular weight was, the more the microcracks and holes on the cross-section of PLGA copolymer materials were, the smoother the cross-sections were.

关键词： high molecular weight PLGA synthesis characterization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of kappa elastin on melanogenesis in A375 human melanoma cells and its related mechanism

引用

Chinese Medical Journal 2012年第22期125卷 4088-4092页

作者： TIAN Shan HE Pei-ying ZHANG jian-zhong chen zhou Peking Univ Peoples Hosp Dept Dermatol Beijing 100044 Peoples R China Peking Univ Peoples Hosp Cent Lab Beijing 100044 Peoples R China

Background Elastin derived peptides can regulate melanocyte precursor development. Ultraviolet irradiation, infrared radiation and heat can increase the synthesis of tropoelastin in human skin epidermis. The aim of this study was to investigate whether the over expressed tropoelastin in epidermis has some role in melanogenesis of melanocytes. Methods A375 human melanoma cells were treated with different concentrations of kappa elastin for 24 hours. A375 human melanoma cells were randomly assigned to control, kappa elastin, and lactose pre-incubated groups. The cell viabilities were detected by the methyl thiazoleterazolium assay. Melanin content and tyrosinase activity in A375 melanoma cells were measured. The expressions of endothelin B receptor （ETBR） mRNA and c-kit mRNA in A375 melanoma cells were measured by quantative reverse transcription polymerase chain reaction. Results Fifty pg/ml of kappa elastin significantly increased the melanin content by 56.64% compared with the control （P 〈0.05）. Kappa elastin increased cellular tyrosinase activity by 46.73% compared with the control at 24 hours （P 〈0.05）. Kappa elastin increased the expressions of ETBR and c-kit mRNA levels by 2.13-fold and 2.47-fold compared with the controls, respectively. When pre-incubating cells with a lactose solution （10 mmol/L）, the inhibition on melanin production was 34.96% compared with the kappa elastin group （P 〈0.05）, tyrosinase activity was inhibited by 29.93% compared with kappa elastin group （P 〈0.05）, and the expressions of ETBR mRNA and c-kit mRNA were decreased by 1.56-fold and 0.82-fold compared with kappa elastin group, respectively. Conclusion Kappa elastin increased the melanogenesis in A375 melanoma cells via the stimulation of tyrosinase activity and the expression of ETBR and c-kit. The over expressed tropoelastin produced by keratinocytes might play a role in melanogenesis of epidermal melanocytes.

关键词： kappa elastin melanin tyrosinase activity endothelin B receptor c-kit

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

STUDY ON OXYGEN ADSORPTION AND CATALYTIC PROPERTIES OF TiO2-BASED CATALYSTS

引用

Journal of Energy Chemistry 1992年第4期 328-340页

作者： QIN Dai-Yi ZHANG Wei-Dong chen Yu zhou jian-Lue chen Yao-Qiang GONG Mao-Chu Analytic and Testing Center,Sichuan University,chengdu,Sichuan 610064

The active oxygen species and active sites for MOC（methane ox-idative coupling）over TiO-based catalysts are studied by ESR ***-gen chemisorption on TiO,La/TiOand Li/TiOwas measured by dynamicESR technique from 295 K to 105 *** process of oxygen adsorption onTiOis *** spectra show that Oions exist largely on TiObut lit-tle on Li/TiOdue to the decrease of surface density of electrons caused bythe substitution of Lifor lattice Tiin Li/*** not detected on *** Oand Oare not likely to be the active species in MOC *** triplet peaks in ESR spectra of Li/TiOare attributed to Ti（Ⅱ）and Ti（Ⅲ）of low coordination numbers,which are active in the presenceof *** of low coordinated Tior Tiare suggested to be responsi-ble for the formation of active oxygen species.

关键词： TiO STUDY ON OXYGEN ADSORPTION AND CATALYTIC PROPERTIES OF TiO2-BASED CATALYSTS

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

STUDY ON OXIDATIVE COUPLING OF METHANE *** OF ADDITIVES ON TiO2 PHASE TRANSITION AND CATALYTIC PERFORMANCE

引用

Journal of Energy Chemistry 1994年第4期 408-416页

作者： GONG Mao-Chu XU Zheng-Hong ZHANG Wei-Dong chen Yao-Qiang zhou jian-Lue chen YuDepartment of Chemistry and Analytical & Testing Center Sichuan University chengdu,Sichuan 610064

The effect of *** and W added to TiOon catalyticperformance for the oxidation coupling of methane （OCM）and on TiOphasetransition was discussed.X-ray diffraction（XRD）analysis and differentialthermal analysis-thermogravimentric analysis （DTA TGA） were used to studythe relation between TiOphase transition and OCM reaction *** showed that Li-La-Mi-W/TiOsystem exhibited high activity andChydrocarbon *** TiO（A）and rutile TiO（R）exhibiteddifferent OCM activity and ***（A）is favorable for the activationof ***（R）is favorable to the formation of *** the transformation from TiO（A） to TiO（R）and *** has nothing to do with TiOphase *** raises mtehaneconversion,resulting in deep *** and La simultaneously added toTiOexhibit a cooperation.

关键词： TiO IO La Li STUDY ON OXIDATIVE COUPLING OF METHANE I.EFFECT OF ADDITIVES ON TiO2 PHASE TRANSITION AND CATALYTIC PERFORMANCE TGA OCM XRD

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Prognostic Significance of Frontal QRS-T Angle in Patients with Idiopathic Dilated Cardiomyopathy

引用

Chinese Medical Journal 2016年第16期129卷 1904-1911页

作者： Sheng-Na Li Xin-Lin Zhang Guo-Long Cai Ruo-Wei Lin He jiang jian-zhou chen Biao Xu Wei Huang Intensive Care Unit Zhejiang Hospital Hangzhou Zhejiang 310031 China Department of Cardiology School of Medicine Affiliated Drum Tower Hospital Nanjing University Nanjing Jiangsu 210008 China Department of Education and Science Zhejiang Hospital Hangzhou Zhejiang 310031 China

Background： Current risk stratification of idiopathic dilated cardiomyopathy （IDC） lacks sufficient sensitivity and specificity. The objective of this study was to investigate the predictive role of frontal QRS-T angles in IDC. Methods： A prospective study with 509 IDC patients was performed from February 2008 to December 2013 in the Affiliated Drum Tower Hospital, Nanjing University School of Medicine. Baseline values and changes in QRS-T angles were recorded. Follow-up was conducted every 6 months. Analyses by Cox Proportional Hazards model were performed to evaluate the association between QRS-T angle and outcomes. The primary outcome of interest was all-cause mortality. Results： During a median follow-up of 34 months, 90 of 316 patients with QRS-T angles 〉90° died compared to 31 of 193 patients with QRS-T angles ≤90° （hazard ratio [HR] 2.4, P 〈 0.001）. Cardiac death was more prevalent in patients with a wide QRS-T angle （HR 2.4, P 〈 0.001）, similar to heart failure rehospitalization （HR = 2.5, P 〈 0.001）. After adjustment for potential prognostic factors, the QRS-T angle was independently associated with all-cause mortality （HR - 2.5, P 〈 0.05）, cardiac mortality （HR = 1.9, P 〈 0. 05）, and heart failure rehospitalization （HR = 2.3, P 〈 0.01）. Optimized therapy significantly narrowed the frontal QRS-T angle （100.9 ±53.4° vs. 107.2 ± 54.4°, P 〈 0.001 ）. The frontal QRS-T angle correlated well with established risk factors, such as left ventricular ejection fraction, brain natriuretic peptide, and New York Heart Association functional class. Conclusions; The frontal QRS-T angle is a powerful predictor of all-cause mortality, cardiac mortality, and worsening heart failure in IDC patients, independent of well-established prognostic factors. Optimized therapy significantly narrows the QRS-T angle, which might be an indicator of medication compliance, but this requires further investigation.

关键词： Electrocardiography Frontal QRS-T Angle Idiopathic Dilated Cardiomyopathy Prognosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

微液滴在超疏水表面的受迫振动及其接触线的固着-移动转变

引用

物理学报 2014年第21期63卷 312-317页

作者：周建臣耿兴国林可君张永建臧渡洋功能软物质与材料课题组空间应用物理与化学教育部重点实验室西北工业大学理学院西安710129 凝固技术国家重点实验室西北工业大学材料学院西安710072

利用高速摄影技术对超疏水表面液滴振动的动态行为进行观测,研究液滴在不同频率下的振动特性.实验发现,液滴的共振频率满足Rayleigh方程,微液滴在超疏水表面具有自由液滴的振动性质.在80—200 Hz的驱动频率范围内,接触线出现了明显的固... 详细信息

利用高速摄影技术对超疏水表面液滴振动的动态行为进行观测,研究液滴在不同频率下的振动特性.实验发现,液滴的共振频率满足Rayleigh方程,微液滴在超疏水表面具有自由液滴的振动性质.在80—200 Hz的驱动频率范围内,接触线出现了明显的固着-移动现象,液滴的振动频率是驱动频率的一半,液滴振动时的形变较大.当驱动频率大于200 Hz时,接触线基本固着,液滴的振动频率近似等于驱动频率,液滴共振时的形态边缘始终有节点存在.分析表明。

关键词：超疏水表面受迫振动共振接触线

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：