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Nuclear Science and Techniques 2024年第1期35卷 18-33页

作者： Xi-Guang Cao Yan-Long Chang Kai Chen Emilio Ciuffoli Li-Min Duan Dong-Liang Fang Chao-Song Gao Surja K.Ghorui Peng-Chong Hu Qiang Hu Si-yuan Huang Ze-yu Huang Lei Lang yu-Lan Li Zhi-Jie Li Tian-yu Liang Jun Liu Chen-Gui Lu Fa-Tai Mai yuan Mei Hao Qiu Xiang-Ming Sun Xiao-xing Tang Hu-Lin Wang Qian-Ming Wang Le Xiao Mu-yun Xiao jian-yu xin Nu Xu Peng Yang Yi-Chen Yang Zhen Yang Zong-Yang yu Dong-Liang Zhang Jun-Wei Zhang Cheng-xin Zhao Dou Zhu NνDEx-100 collaboration Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Lanzhou University Lanzhou 730000China Central China Normal University Wuhan 430079China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Lawrence Berkeley National Laboratory BerkeleyCA 94720USA North China University of Water Resources and Electric Power Zhengzhou 450045China 不详

Observing nuclear neutrinoless double beta (0vββ) decay would be a revolutionary result in particle physics.Observing such a decay would prove that the neutrinos are their own antiparticles,help to study the absolute mass of neutrinos,explore the origin of their mass,and may explain the matter-antimatter asymmetry in our universe by lepton number violation.We propose developing a time projection chamber (TPC) using high-pressure ^(82)SeF_(6) gas and Topmetal silicon sensors for readout in the China Jinping Underground Laboratory (CJPL) to search for neutrinoless double beta decay of82Se,called the NvDEx experiment.Besides being located at CJPL with the world’s thickest rock shielding,NvDEx combines the advantages of the high Qββ(2.996 MeV) of82Se and the TPC’s ability to distinguish signal and background events using their different topological characteristics.This makes NvDEx unique,with great potential for low-background and high-sensitivity 0 vββsearches.NvDEx-100,a NvDEx experiment phase with 100 kg of SeF_(6)gas,is being built,with plans to complete installation at CJPL by 2025.This report introduces 0 vββ physics,the NvDEx concept and its advantages,and the schematic design of NvDEx-100,its subsystems,and background and sensitivity estimation.

关键词： Neutrinoless double beta decay Time projection chamber ^(82)SeF_(6) China Jinping Underground Laboratory

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射流参数对双孔液态CO_(2)相变冲击岩石裂纹扩展的影响

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工程爆破 2024年第2期30卷 98-109,158页

作者：于建新王云蒙王金星陈晨河南理工大学土木工程学院河南焦作454003 河南省地下工程与灾变防控重点实验室河南焦作454003 台州交通勘测设计院有限公司浙江台州318001

液态CO_(2)相变作用时的射流形状与冲击方向影响着破岩效果。基于自行构建的试验系统,结合LS-DYNA数值模拟,研究了双孔液态CO_(2)在不同气流释放方向组合下的岩石裂纹扩展规律。结果表明:双孔X方向相背冲击时,岩石裂纹并不能在两孔之间... 详细信息

液态CO_(2)相变作用时的射流形状与冲击方向影响着破岩效果。基于自行构建的试验系统,结合LS-DYNA数值模拟,研究了双孔液态CO_(2)在不同气流释放方向组合下的岩石裂纹扩展规律。结果表明:双孔X方向相背冲击时,岩石裂纹并不能在两孔之间扩展贯通。双孔X方向相对冲击时,两孔之间形成贯穿裂纹。双孔Y方向同向冲击时,裂纹沿初始冲击方向扩展,并在孔周围扩展形成多条裂纹。数值模拟结果表明:在不同释放口组合冲击作用下,X方向相对冲击时裂纹在两孔之间形成贯穿,初始裂纹继续扩展贯穿至前后侧面。X方向相背冲击下的试样裂隙主要向预留孔四周扩展。Y方向同向冲击下试样内部裂隙沿初始气流冲击方向的反方向扩展,并未形成贯穿裂纹。从裂纹定向扩展效果而言,双孔X方向相对冲击效果最好,Y方向同向冲击次之,X方向相背冲击最差。从顶面主裂纹扩展数量而言,X方向相背冲击最多,Y方向同向冲击次之,X方向相对冲击最少。研究结果可为CO_(2)冲击致裂技术应用提供指导。

关键词：液态CO_(2) 相变冲击裂纹扩展损伤分析数值模拟

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“补肾益髓”法艾灸治疗膝关节骨关节炎的疗效观察

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针刺研究 2024年第2期49卷 171-176页

作者：王佩王刘玉谢舜名王莉莉王红恩于建新常永志朱维杰江苏省太湖康复医院康复医学中心江苏省太湖疗养院江苏省健康评估与干预研究中心江苏无锡214026

目的:比较两种不同艾灸取穴方案治疗膝关节骨关节炎(KOA)的临床疗效,并观察其对患者血清白细胞介素(IL)-1α、IL-17A、肿瘤坏死因子α(TNF-α)、骨钙素(BGP)、骨保护素(OPG)含量的影响。方法:KOA患者随机分为观察组(40例,脱落2例)和对照... 详细信息

目的:比较两种不同艾灸取穴方案治疗膝关节骨关节炎(KOA)的临床疗效,并观察其对患者血清白细胞介素(IL)-1α、IL-17A、肿瘤坏死因子α(TNF-α)、骨钙素(BGP)、骨保护素(OPG)含量的影响。方法:KOA患者随机分为观察组(40例,脱落2例)和对照组(40例,脱落3例)。观察组艾灸患侧内膝眼、犊鼻、足三里、大杼、悬钟、涌泉,对照组艾灸患侧内膝眼、犊鼻、足三里,每次30 min,每周治疗3次,治疗4周。观察两组患者治疗前后西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分和视觉模拟量尺(VAS)评分,检测两组患者治疗前后血清IL-1α、IL-17A、TNF-α、BGP、OPG含量。结果:与本组治疗前比较,两组患者治疗后WOMAC评分、VAS评分及血清IL-1α、IL-17A、TNF-α含量均降低(P<0.05),血清BGP、OPG含量升高(P<0.05)。观察组的WOMAC评分、VAS评分及血清IL-1α、TNF-α含量低于对照组(P<0.05),血清BGP、OPG含量高于对照组(P<0.05)。观察组总有效率为89.5%(34/38),对照组总有效率为83.8%(31/37),差异无统计学意义。结论:“补肾益髓”的艾灸疗法可缓解关节疼痛,改善关节功能,降低炎性因子水平,改善骨代谢指标,作用优于局部取穴。

关键词：艾灸膝关节骨关节炎骨代谢炎性因子

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Lipid metabolism, amino acid metabolism, and prostate cancer: a crucial metabolic journey

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Asian Journal of Andrology 2024年第2期26卷 123-134页

作者： Lin Chen yu-xin Xu yuan-Shuo Wang jian-Liang Zhou School of Pharmacy Hangzhou Normal UniversityHangzhou 311121China Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province Hangzhou Normal UniversityHangzhou 311121China School of Pharmacy Guangxi Medical UniversityNanning530021China

Prostate cancer(PCa)is one of the most common malignancies in males worldwide,and its development and progression involve the regulation of multiple metabolic pathways.Alterations in lipid metabolism affect the proliferation and metastatic capabilities of PCa cells.Cancer cells increase lipid synthesis and regulate fatty acid oxidation to meet their growth and energy demands.Similarly,changes occur in amino acid metabolism in PCa.Cancer cells exhibit an increased demand for specific amino acids,and they regulate amino acid transport and metabolic pathways to fulfill their proliferation and survival requirements.These changes are closely associated with disease progression and treatment response in PCa cells.Therefore,a comprehensive investigation of the metabolic characteristics of PCa is expected to offer novel insights and approaches for the early diagnosis and treatment of this disease.

关键词： amino acid metabolism lipid metabolism metabolic pathways prostate cancer treatment strategies

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Facile synthesis of high-brightness green-emitting carbon dots with narrow bandwidth towards backlight display

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Chinese Chemical Letters 2024年第5期35卷 277-282页

作者： Rui Cheng Tingting Zhang xin Huang jian yu State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 210009China

High-performance carbon dots(CDs)allowing the application in high-end display devices are highly desirable and usually limited by the absence of simple and easy synthesis methods.In this work,we exploited an easy-to-implement strategy for the one-step synthesis of green-emitting CDs(G-CDs)with superb optical properties.The G-CDs were synthesized using m-phenylenediamine(m-PD)as a single precursor,and the reaction reacted at 180℃for 12 h The resultant G-CDs exhibit high-purity and excitationindependent green fluorescence with the photoluminescence(PL)peak located at 516 nm,full width at half maximum(FWHM)of 46 nm,and PL quantum yield(QY)of∼80%under the 470nm excitation light.The G-CDs and corresponding composite film prepared with polyvinyl butyral(G-CDs@PVB)exhibit good PL stability after undergoing long-time storage for one year and 360 h exposure under 460nm blue light.The G-CDs@PVB film was used as color-conversion materials in green-emitting light-emitting diode(LED)application,exhibiting a Commission internationale de l’Eclairage(CIE)chromaticity coordinate of(0.21,0.44).The film was also used in CD-based liquid crystal display(CD-LCD)application,achieving a color gamut value of 85%.This work will offer a working basis for the synthesis of high-performance CDs as well as their application in displays.

关键词： Carbon dots One-step synthesis Narrow bandwidth High quantum yield Display

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Recent progress on Sn_(3)O_(4)nanomaterials for photocatalytic applications

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International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 231-244页

作者： xin yu Congcong Li jian Zhang Lili Zhao Jinbo Pang Longhua Ding Institute for Advanced Interdisciplinary Research(iAIR) School of Chemistry and Chemical EngineeringUniversity of JinanJinan 250022China School of Sino-German Engineering Shanghai Technical Institute of Electronics and InformationShanghai 201411China Division of Systems and Synthetic Biology Department of Life SciencesChalmers University of Technology41296 GöteborgSweden

Tin(IV)oxide(Sn_(3)O_(4))is layered tin and exhibits mixed valence states.It has emerged as a highly promising visible-light pho-tocatalyst,attracting considerable attention.This comprehensive review is aimed at providing a detailed overview of the latest advance-ments in research,applications,advantages,and challenges associated with Sn_(3)O_(4)photocatalytic nanomaterials.The fundamental con-cepts and principles of Sn_(3)O_(4)are introduced.Sn_(3)O_(4)possesses a unique crystal structure and optoelectronic properties that allow it to ab-sorb visible light efficiently and generate photoexcited charge carriers that drive photocatalytic reactions.Subsequently,strategies for the control and improved performance of Sn_(3)O_(4)photocatalytic nanomaterials are discussed.Morphology control,ion doping,and hetero-structure construction are widely employed in the optimization of the photocatalytic performance of Sn_(3)O_(4)materials.The effective imple-mentation of these strategies improves the photocatalytic activity and stability of Sn_(3)O_(4)nanomaterials.Furthermore,the review explores the diverse applications of Sn_(3)O_(4)photocatalytic nanomaterials in various fields,such as photocatalytic degradation,photocatalytic hydro-gen production,photocatalytic reduction of carbon dioxide,solar cells,photocatalytic sterilization,and optoelectronic sensors.The discus-sion focuses on the potential of Sn_(3)O_(4)-based nanomaterials in these applications,highlighting their unique attributes and functionalities.Finally,the review provides an outlook on the future development directions in the field and offers guidance for the exploration and de-velopment of novel and efficient Sn_(3)O_(4)-based nanomaterials.Through the identification of emerging research areas and potential avenues for improvement,this review aims to stimulate further advancements in Sn_(3)O_(4)-based photocatalysis and facilitate the translation of this promising technology into practical applications.

关键词： photocatalysis Sn_(3)O_(4)nanomaterials building heterostructures antibacterial therapy water splitting

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Accurate simulations of pure-viscoacoustic wave propagation in tilted transversely isotropic media

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Petroleum Science 2024年第2期21卷 866-884页

作者： Qiang Mao jian-Ping Huang xin-Ru Mu Ji-Dong Yang yu-jian Zhang Geosciences Department China University of Petroleum(East China)Qingdao266580ShandongChina Pilot National Laboratory for Marine Science and Technology(Qingdao) Qingdao266207ShandongChina

Forward modeling of seismic wave propagation is crucial for the realization of reverse time migration(RTM) and full waveform inversion(FWI) in attenuating transversely isotropic media. To describe the attenuation and anisotropy properties of subsurface media, the pure-viscoacoustic anisotropic wave equations are established for wavefield simulations, because they can provide clear and stable wavefields. However, due to the use of several approximations in deriving the wave equation and the introduction of a fractional Laplacian approximation in solving the derived equation, the wavefields simulated by the previous pure-viscoacoustic tilted transversely isotropic(TTI) wave equations has low accuracy. To accurately simulate wavefields in media with velocity anisotropy and attenuation anisotropy, we first derive a new pure-viscoacoustic TTI wave equation from the exact complex-valued dispersion formula in viscoelastic vertical transversely isotropic(VTI) media. Then, we present the hybrid finite-difference and low-rank decomposition(HFDLRD) method to accurately solve our proposed pure-viscoacoustic TTI wave equation. Theoretical analysis and numerical examples suggest that our pure-viscoacoustic TTI wave equation has higher accuracy than previous pure-viscoacoustic TTI wave equations in describing q P-wave kinematic and attenuation characteristics. Additionally, the numerical experiment in a simple two-layer model shows that the HFDLRD technique outperforms the hybrid finite-difference and pseudo-spectral(HFDPS) method in terms of accuracy of wavefield modeling.

关键词： Pure-viscoacoustic TTI wave equation Attenuation anisotropy Seismic modeling Low-rank decomposition method

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Water modeling on fluid flow and mixing phenomena in a BOF steelmaking converter

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Journal of Iron and Steel Research(International) 2024年第3期31卷 595-607页

作者： xin-yu Cai Hao-jian Duan Ding-han Li Anjun Xu Li-feng Zhang School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing 100083China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144China

A 1∶8 physical water model was constructed to investigate the fluid flow and mixing phenomena in the basic oxygen furnace(BOF)converter.The particle image velocimetry was employed to measure the velocity distribution of the bath and the high-speed camera was applied to capture the cavity shape in the combined blowing BOF converter.The mixing time for varied operating conditions was measured by the stimulus-response approach.The cavity depth increased with the decrease in the lance height and the increase in the top gas flow rate while the bottom blowing gas had little influence on the cavity depth.The minimum cavity depth was obtained under the condition of a 69.8 m^(3)/h top gas flow rate,a 287.5 mm lance height and a 0.93 m^(3)/h bottom blowing gas flow rate,which was 161.2 mm.The mixing time decreased as the lance height decreased and the top blowing gas flow rate increased.The mixing time was first decreased and then increased with the increase in the bottom gas flow rate.With the condition of 69.8 m^(3)/h gas flow rate of top blowing,the 287.5 mm lance height and the 0.93 m^(3)/h gas flow rate of bottom blowing,the mixing time in the converter was 48.65 s.The empirical formula between the stirring power and the mixing time in the converter was calculated.

关键词： Water model Fluid flow Particle image velocimetry Mixing time BOF converter

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Hemorrhagic cystitis in gastric cancer after nanoparticle albuminbound paclitaxel:A case report

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1084-1090页

作者： xin-Jie Zhang jian Lou Department of Cancer Center The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND The advanced first-line regimen for advanced gastric cancer is based on a combination of fluoropyrimidine and platinum and/or paclitaxel(PTX),forming a two-or three-drug regimen.Compared to conventional PTX,nanoparticle albumin-bound PTX(Nab-PTX)has better therapeutic effects and fewer adverse effects reported in studies.Nab-PTX is a great option for patients presenting with advanced gastric cancer.Herein,we highlight an adverse event(hemorrhagic cystitis)of Nab-PTX in advanced gastric cancer.CASE SUMMARY A 55-year-old male was diagnosed with lymph node metastasis after a laparo-scopic-assisted radical gastrectomy for gastric cancer that was treated by Nab-PTX and S-1(AS).On the 15th day after treatment with AS,he was diagnosed with hemorrhagic cystitis.CONCLUSION Physicians should be aware that hemorrhagic cystitis is a potential adverse event associated with Nab-PTX treatment.

关键词： Nanoparticle albumin-bound paclitaxel Hemorrhagic cystitis Gastric cancer Adverse event Case report

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Study on tungsten sintering temperature field based on electromagnetic simulation and computational fluid dynamics

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Tungsten 2024年第2期6卷 355-366页

作者： Lu-Yan Wang yue-Guang yu jian-xin Dong Kai-Ping Du Shan-yu Liu Cao-Bing Li University of Science and Technology Beijing Beijing 100083China BGRIMM Technology Group Beijing 100160China China Iron&Steel Research Institute Group Beijing 100081China

In order to study the influence of various sintering variables more intuitively and clearly,electromagnetic field analysis and computational fl uid dynamics are used to analyze the infl uence of gas flow,heating power and other process parameters on the temperature range of medium-frequency sintering in this paper.The results indicate that the uniformity of temperature fi eld is determined by the gas flow rate and heating power.When the heating power is 50 kW,the stable temperature drops about 10 K for every 1 m^(3)·h^(−1)increase of hydrogen flow.The peak value of the maximum temperature diff erence on the tungsten rods gradually increases with the increase of the hydrogen flow rate,and it appears slightly later.The temperature distribution of tungsten rods in furnace is similar with diff erent hydrogen flow rate.At the same time,the closer to the furnace wall,the higher the temperature of the tungsten rod.The temperature diff erence between tungsten rods mainly occurred within 1 h after the beginning of heating.Increasing the heating power can improve the stable temperature,but has little eff ect on the heating time.Increasing heating power can increase the peak value of the maximum temperature diff erence on the tungsten rods,but has little eff ect on the occurrence time of the peak value of the maximum temperature diff erence on the tungsten rods.Increasing the heating power will increase the temperature diff erence of a single tungsten rod,but the temperature diff erence of a single tungsten rod never exceeds 65 K.This study can be used to guide the process optimization design.Combined with numerical simulation calculation,the sintering parameters with low energy consumption and high temperature uniformity can be quickly and eff ectively found,thus improving the microstructure and properties of sintered tungsten products.

关键词： Tungsten products Sintering Hydrogen flow rate Heating power

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