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Estrogen receptor expression in adrenocortical carcinoma

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第1期10卷 1-6页

作者： Xiao-cao SHEN Cai-xiao gu Yi-qing QIU Chuan-jun DU Yan-biao FU jian-jun WU Urology Department School of Medicine Zhejiang University Hangzhou 310009 China Pathology Department School of Medicine Zhejiang University Hangzhou 310009 China Radiology Department the Second AJfiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

Objective: Adrenocortical carcinoma (ACC) is a rare but highly malignant tumor, and its diagnosis is mostly delayed and prognosis is poor. We report estrogen receptor (ER) expression in this tumor and our clinical experiences with 17 ACC cases. Methods: The data of the 17 patients (9 females and 8 males, age range from 16 to 69 years, mean age of 42.6 years) with ACC were reviewed, and symptoms, diagnostic procedures, treatment, and results of follow-up were evaluated. Immunohistochemistry was used to detect ER expression in tumor samples from the 17 patients. Results: At the time of diagnosis, 4 tumors were classified as Stage I, 4 as Stage II, 3 as Stage III, and 6 as Stage IV. Eight patients demonstrated positive nuclear immunostaining of ER. The prognosis of patients with ER positive was significantly better (P<0.05) than that of patients with ER negative, with 1- and 5-year survival rates at 86% and 60% for ER-positive patients, and 38% and 0% for ER-negative patients, respectively. Conclusion: ER-positivity may be one of the factors associated with a worse prognosis of ACC.

关键词： Adrenocortical carcinoma (ACC) Estrogen receptor (ER) Diagnosis Treatment

Intelligent Spectrum Management Based on Radio Map for Cloud-Based Satellite and Terrestrial Spectrum Shared Networks

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China Communications 2021年第12期18卷 108-118页

作者： Ximu Zhang Min Jia Xuemai gu qing guo Communication Research Center School of Electronics and Information EngineeringHarbin Institute of TechnologyHarbin 150080China

Cloud-based satellite and terrestrial spectrum shared networks(CB-STSSN)combines the triple advantages of efficient and flexible net-work management of heterogeneous cloud access(H-CRAN),vast coverage of satellite networks,and good communication quality of terrestrial *** to the complementary coverage characteristics,any-time and anywhere high-speed communications can be achieved to meet the various needs of *** scarcity of spectrum resources is a common prob-lem in both satellite and terrestrial *** or-der to improve resource utilization,the spectrum is shared not only within each component but also be-tween satellite beams and terrestrial cells,which intro-duces inter-component *** this end,this paper first proposes an analytical framework which considers the inter-component interferences induced by spectrum sharing(SS).An intelligent SS scheme based on radio map(RM)consisting of LSTM-based beam prediction(BP),transfer learning-based spec-trum prediction(SP)and joint non-preemptive prior-ity and preemptive priority(J-NPAP)-based propor-tional fair spectrum allocation is than *** simulation result shows that the spectrum utilization rate of CB-STSSN is improved and user blocking rate and waiting probability are decreased by the proposed scheme.

关键词： cloud-based satellite and terrestrial spec-trum shared networks spectrum management inter-ference analysis spectrum utilization rate

Introducing an External Terminal Operator or Not? The Decision of Ports in a Duopoly Market

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Journal of Systems Science & Complexity 2020年第1期33卷 146-166页

作者： guO Libin LI jian LIU qing XING Wei College of Information Science and Technology Beijing University of Chemical TechnologyBeijing 100029China School of Management Qufu Normal UniversityRizhao 276826China Research Base of Beijing Modern Manufacturing Development College of Economics and ManagementBeijing University of TechnologyBeijing 100124China Hamburg Business School University of HamburgHamburg 20148Germany School of Economics and Management China University of PetroleumQingdao 266580China

Facing with increasing competition,many ports are taking innovative approaches to improve productivity and *** a variety of methods,introducing external terminal operators(ETOs)while the port acts as a landlord to collect"rents"from those operators for conducting terminal activities inside the port is regarded as an effective way and is commonly observed in *** paper analyzes the decisions of two competing ports about whether to introduce their respective ETOs using a three-stage non-cooperative game model when there already exists a port’s self-operation terminal operator(STO).At the first stage,the two ports simultaneously decide whether to introduce an *** a port decided to introduce an ETO,at the second stage,it will further decide the unit fee to charge from the *** the third stage,the two ports and the introduced ETO(s)simultaneously decide their respective profit-maximizing output *** findings indicate the equilibrium is both ports will introduce their respective ETOs,but when the ports and ETOs are substitutable in the sense of having the same level of productivity,the equilibrium solution is only one port should introduce an *** simulation results show that even if one of ETOs is inefficient this still hold true.

关键词： External terminal operator intra-port competition landlord port mode port authority self-operation terminal operator

Probing new physics in dimension-8 neutral gauge couplings at e^+e^-colliders

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Science China(Physics,Mechanics & Astronomy) 2021年第2期64卷 2-26页

作者： John Ellis Hong-jian He Rui-qing Xiao Department of Physics Kings College LondonStrandLondonWC2R 2LSUK Theoretical Physics Department CERNCH-1211Geneva 23Switzerland NICPB Rävala 10Tallinn10143Estonia Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Key Laboratory for Particle Physics and CosmologyShanghai Jiao Tong UniversityShanghai200240China Institute of Modern Physics and Department of Physics Tsinghua UniversityBeijing100084China Center for High Energy Physics Peking UniversityBeijing100871China

Neutral triple gauge couplings(nTGCs)are absent in the standard model effective theory up to dimension-6 operators,but could arise from dimension-8 effective *** this work,we study the pure gauge operators of dimension-8 that contribute to nTGCs and are independent of the dimension-8 operator involving the Higgs *** show that the pure gauge operators generate both ZγZ^*and Zγγ^*vertices with rapid energy dependence∝E^5,which can be probed sensitively via the reaction e^+e^-→Zγ.We demonstrate that measuring the nTGCs via the reaction e^+e^-→Zγfollowed by Z→qq decays can probe the new physics scales of dimension-8 pure gauge operators up to the range(1-5)TeV at the CEPC,FCC-ee and ILC colliders with s~(1/2)=(0.25-1)TeV,and up to the range(10-16)TeV at CLIC with s~(1/2)=(3-5)TeV,assuming in each case an integrated luminosity of 5 ab~(-1).We compare these sensitivities with the corresponding probes of the dimension-8 nTGC operators involving Higgs doublets and the dimension-8 fermionic contact operators that contribute to the e^+e^-Zγvertex.

关键词： neutral triple gauge couplings new physics beyond the standard model effective field theory e^+e^-colliders

Synthesis of flexible inter-plant heat exchanger networks: A decomposition method considering intermedium fluid circles

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CHINESE JOURNAL OF CHEMICAL ENGINEERING 2024年第11期75卷 62-73页

作者： Tao, Ran gu, Siwen Liu, Linlin Du, jian Dalian Univ Technol Sch Chem Engn Inst Proc Syst Engn Dalian 116023 Peoples R China Changzhou Inst Technol Sch Photoelect Engn Changzhou 213032 Peoples R China

The traditional methods for synthesizing flexible heat exchanger networks (HENs) are not directly applicable to inter-plant HEN challenges, primarily due to the spread of system uncertainty across plants via intermedium fluid circles. This complicates the synthesis process significantly. To tackle this issue, this study proposes a decomposed stepwise methodology to facilitate the flexible synthesis of the interplant HENs performing indirect heat integration. A decomposition strategy is proposed to divide the overall network into manageable sub-networks by dissecting the intermedium fluid circles. To address the variability in intermedium fluid temperatures, a temperature fluctuation analysis approach is developed and a heuristic rule is introduced to maintain the temperature feasibility of the intermedium fluids. To ensure adequate flexibility and cost-effectiveness of the designed networks, flexibility analysis and network retrofit steps are conducted through model-based optimization techniques. The efficacy of the method is demonstrated through two case studies, showing its potential in achieving the desired operational flexibility for inter-plant HENs. (c) 2024 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

关键词： Inter-plant heat exchanger networks (HENs) Indirect heat integration Flexible synthesis Flexible analysis Decomposition method

Seismic performance evaluation of steel frame-steel plate shear walls system based on the capacity spectrum method

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第3期9卷 322-329页

作者： jian-hua SHAO Qiang gu Yong-kang SHEN College of Civil Engineering Hohai University Nanjing 210098 China Department of Civil Engineering Suzhou University of Science and Technology Suzhou 215011 China

This paper presents some methods that the standard acceleration design response spectra derived from the present China code for seismic design of buildings are transformed into the seismic demand spectra, and that the base shear force-roof displacement curve of structure is converted to the capacity spectrum of an equivalent single-degree-of-freedom （SDOF） system. The capacity spectrum method （CSM） is programmed by means of MATLABT.0 computer language. A dual lateral force resisting system of 10-story steel frame-steel plate shear walls （SPSW） is designed according to the corresponding China design codes. The base shear force-roof displacement curve of structure subjected to the monotonic increasing lateral inverse triangular load is obtained by applying the equivalent strip model to stimulate SPSW and by using the finite element analysis software SAP2000 to make Pushover analysis. The seismic performance of this dual system subjected to three different conditions, i.e. the 8-intensity frequently occurred earthquake, fortification earthquake and seldom occurred earthquake, is evaluated by CSM program. The excessive safety of steel frame-SPSW system designed according to the present China design codes is pointed out and a new design method is suggested.

关键词： Steel frame-steel plate shear walls (SPSW) system Capacity spectrum method (CSM) Seismic demand spectrum Base shear force-roof displacement Seismic performance evaluation

Superconducting Single-Layer T-Graphene and Novel Synthesis Routes

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Chinese Physics Letters 2019年第9期36卷 46-63页

作者： Qinyan gu Dingyu Xing jian Sun National Laboratory of Solid State Microstructures School of Physics and Collaborative Innovation Center of Ad vanced MicrostructuresNanjing UniversityNanjing 210093

Single-layer superconductors are ideal materials for fabricating superconducting nano ***,up to date,very few single-layer elemental superconductors have been predicted and especially no one has been successfully synthesized ***,using crystal structure search techniques and ab initio calculations,we predict that a single-layer planar carbon sheet with 4-and 8-membered rings called T-graphene is a new intrinsic elemental superconductor with superconducting critical temperature(Tc)up to around 20.8 *** importantly,we propose a synthesis route to obtain such a single-layer T-graphene,that is,a T-graphene potassium intercalation compound(C4 K with P4/mmm symmetry)is firstly synthesized at high pressure(>11.5 GPa)and then quenched to ambient condition;and finally,the single-layer T-graphene can be either exfoliated using the electrochemical method from the bulk C4 K,or peeled off from bulk T-graphite C4,where C4 can be obtained from C4 K by evaporating the K ***,we find that the calculated Tc of C4 K is about 30.4 K at 0 GPa,which sets a new record for layered carbon-based *** present findings add a new class of carbon-based *** particular,once the single-layer T-graphene is synthesized,it can pave the way for fabricating superconducting devices together with other 2 D materials using the layer-by-layer growth techniques.

关键词： red Superconducting Single-Layer T-Graphene and Novel Synthesis Routes Graphene

PREDICTION OF VORTEX-INDUCED VIBRATION OF LONG FLEXIBLE CYLINDERS MODELED BY A COUPLED NONLINEAR OSCILLATOR:INTEGRAL TRANSFORM SOLUTION

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Journal of Hydrodynamics 2012年第6期24卷 888-898页

作者： gu Ji-jun AN Chen LEVI Carlos SU jian Ocean Engineering Program COPPEUniversidade Federal do Rio de Janeiro Nuclear Engineering Program COPPEUniversidade Federal do Rio de Janeiro

The Generalized Integral Transform Technique （GITT） was applied to predict dynamic response of Vortex-Induced Vibration （VIV） of a long flexible cylinder. A nonlinear wake oscillator model was used to represent the cross-flow force acting on the cylinder, leading to a coupled system of second-order Partial Differential Equations （PDEs） in temporal variable. The GITT approach was used to transform the system of PDEs to a system of Ordinary Differential Equations （ODEs）, which was numerically solved by using the Adams-Moulton and Gear method （DIVPAG） developed by the International Mathematics and Statistics Library （IMSL）. Numerical results were presented for comparison to those given by the finite difference method and experimental results, allowing a critical evaluation of the technique performance. The influence of variation of mean axial tension induced by elongation of flexible cylinder was evaluated, which was shown to be not negligible in numerical simulation of VIV of a long flexible cylinder.

关键词： Vortex-Induced Vibration (VIV) nonlinear wake oscillator flexible cylinder integral transform

Winding Capacitance Dividing Method for Powerformer

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高电压技术 2008年第5期34卷 966-972页

作者： TIAN qing LIN Xiang-ning LI jian-jian TAO Yong-hong Southeast Shanxi Ultra High Voltage Administrative Bureau State Grid Operation Company Limited Changzhi 047100 China Department of Electrical Engineering China Three Gorges University Yichang 443002 China State Grid Operation of Company Limited Beijing 100005 China Department of Electrical Information Xihua University Chengdu 610039 China

It presents a method which can equivalently arrange the capacitance distribution along with the winding of the generator on the terminal and neutral respectively in a reasonable partition,particularly for a type of high-voltage graded insulated cable wound generator,*** winding of the Powerformer adopts graded insulation,which leads to the various cable thicknesses in different portion of the winding,and thus,the uneven capacitance *** large capacitive currents and large transient outrush currents resulting from the cable consisting of the stator winding of Powerformer may cause problems to the generator differential *** of literatures available in the field of compensated differential protection focus on the charging current compensation for long transmission line,instead of for *** authors give a method which can be used to compensate the capacitive current wholly to improve the reliability of the differential protection of *** is proved that the distributed capacitance can be equivalent as the lump circuit with a capacitance partition coefficient ρ,and ρ is proved as a constant no matter whether the generator experiences the normal operation,external phase(s) fault or internal phase(s) *** formula of the partition coefficient is provided and the corresponding equivalent circuit of the Powerformer cable to calculate capacitance currents is *** analysis programming resolving the minimum value of the coefficient ρ is written in MATLAB 7.0/m according to this formula,using the function fmincon() which can work in any type of constraint *** program always gets the same global minimum points under the different initial values condition which proves our point by mathematical *** this new approach to winding capacitance dividing method,the protection scheme used for Powerformer can be validated and improved accordingly.

关键词：电力系统电容分配模式动力设备