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Automated federated learning‐based adversarial attack and defence in industrial control systems

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IET Cyber-Systems and Robotics 2024年第2期6卷 109-127页

作者： Guo-Qiang Zeng Jun-Min Shao Kang-Di Lu Guang-Gang Geng jian weng College of Cyber Security Jinan UniversityGuangzhouChina National Joint Engineering Research Center of Network Security Detection and Protection Technology Jinan UniversityGuangzhouChina College of Information Science and Technology Donghua UniversityShanghaiChina

With the development of deep learning and federated learning(FL),federated intrusion detection systems(IDSs)based on deep learning have played a significant role in securing industrial control systems(ICSs).However,adversarial attacks on ICSs may compromise the ability of deep learning-based IDSs to accurately detect cyberattacks,leading to serious ***,in the process of generating adversarial samples,the selection of replacement models lacks an effective method,which may not fully expose the vulnerabilities of the *** authors first propose an automated FL-based method to generate adversarial samples in ICSs,called AFL-GAS,which uses the prin-ciple of transfer attack and fully considers the importance of replacement models during the process of adversarial sample *** the proposed AFL-GAS method,a lightweight neural architecture search method is developed to find the optimised replacement model composed of a combination of four lightweight basic ***,to enhance the adversarial robustness,the authors propose a multi-objective neural archi-tecture search-based IDS method against adversarial attacks in ICSs,called MoNAS-IDSAA,by considering both classification performance on regular samples and adver-sarial robustness *** experimental results on three widely used intrusion detection datasets in ICSs,such as secure water treatment(SWaT),Water Distribution,and Power System Attack,demonstrate that the proposed AFL-GAS method has obvious advantages in evasion rate and lightweight compared with other four ***,the proposed MoNAS-IDSAA method not only has a better classification performance,but also has obvious advantages in model adversarial robustness compared with one manually designed federated adversarial learning-based IDS method.

关键词： adversarial attacks adversarial robustness automated federated learning Industrial control system intrusion

Contamination assessment,source apportionment and associated health risks of PTEs in agricultural soil under five land-use patterns in Sanya,China

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China Geology 2024年第3期7卷 469-479页

作者： jian-zhou Yang Yan-gang Fu Qiu-li Gong Sheng-ming Ma Jing-jing Gong jian-weng Gao Zhen-liang Wang Yong-wen Cai Shi-xin Tang Institute of Geophysical and Geochemical Exploration Chinese Academy of Geological SciencesChina Geological SurveyLangfang 065000China Key Laboratory of Coupling Process and Effect of Natural Resources Elements Ministry of Natural ResourcesBeijing 100055China

To understand the levels of potentially toxic elements(PTEs)contamination in soils and their effects on human health from different agricultural land use in Sanya,China.128 soil samples(64 topsoil samples and corresponding subsoil samples)were collected from the five representative land-use *** coupled plasma mass spectrometry(ICP-MS),Atomic fluorescence spectrometry(AFS),and Inductively coupled plasma optical emission spectrometry(ICP-OES)were used to determine the content of PTEs(As,Cd,Hg,Cu,Cr,Ni,Pb,Zn,Co,Mo,Sb,and V).Correlation analysis and factor analysis were used to determine the source of ***-accumulation index(I_(geo)),hazard quotient(HQ),and total carcinogenic risk index(TR)were used to measure the PTEs contamination and its relative health *** showed that the average values of 12 PTEs in topsoil were higher than the Hainan soil geochemical baseline,showing different degrees of PTEs accumulation *** concentration of PTEs in the topsoil was lower than those in the subsoil except for Cd and *** I_(geo)revealed that the major accumulated element in soils was As followed by *** apportionment suggested that parent materials and agricultural practices were the dominant factors for PTEs accumulation in the *** risks of soil samples from five land-use patterns presented a trend of paddy field>dry field>woodland>orchard>garden ***,the HQ values of 12 PTEs were less than the recommended limit of HQ=1,representing that there are no non-carcinogenic risks of PTEs for children and adults in the study *** TR values are within 6.95×10^(-6)-1.38×10^(-5),which corresponds to the low *** the PTEs in the agricultural soil of the study area show little influence on the health status of the local population.

关键词： Potentially toxic trace elements(PTEs) Soils Land-use Geo-accumulation index(Igeo) Hazard quotient(HQ) Total carcinogenic risk index(TR) Source apportionment Health risk Agricutural geological survey engineering

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基于改进ORB的视觉里程计算法

控制与决策 2024年第3期39卷 819-826页

作者：翁剑鸿雷群楼陶杰鲁仁全广东工业大学自动化学院广州510006

ORB-SLAM 2因高斯金字塔离散、量化尺度的因素,易造成尺度量化误差.针对这一缺陷,提出孪生过滤器算法.通过在对数极坐标系下进行描述子构造,减少其量化误差,并在同层金字塔中构造笛卡尔坐标系下孪生描述子,利用该描述子距离实现过滤,从... 详细信息

ORB-SLAM 2因高斯金字塔离散、量化尺度的因素,易造成尺度量化误差.针对这一缺陷,提出孪生过滤器算法.通过在对数极坐标系下进行描述子构造,减少其量化误差,并在同层金字塔中构造笛卡尔坐标系下孪生描述子,利用该描述子距离实现过滤,从而提高特征点的尺度不变性,增强其匹配准确率.同时,针对ORB-SLAM 2的四叉树算法过度追求离散度而忽略特征点质量问题这一情况,提出深度有限四叉树算法.利用特征点提取阈值以及特征点所在金字塔层进行自适应深度阈值设置,减小弱特征点区域的划分次数,从而减少弱特征点提取数目.实验表明,所提出算法能够有效提高特征点离散度、正确匹配特征点数目和匹配精度,具有更高的轨迹精度.

关键词：视觉里程计四叉树算法孪生过滤器离散度 ORB-SLAM 2

慢病毒介导长链非编码RNA XLOC_015548基因编辑的C2C12细胞模型建立

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中华骨与关节外科杂志 2024年第2期17卷 154-161页

作者：翁鉴齐天天魏懿浩于斐北京大学深圳医院骨关节科广东深圳518036 骨科生物材料国家地方联合工程研究中心广东深圳518036 深圳市骨科疾病与生物材料研究重点实验室广东深圳518036

目的:探讨长链非编码RNA XLOC_015548基因敲减或过表达后C2C12小鼠成肌细胞中目的基因及成肌分化因子的表达情况。构建XLOC_015548基因编辑成肌细胞模型,为今后进一步实验提供基础。方法:根据RNA测序结果得出相关序列,拟构建XLOC_01554... 详细信息

目的:探讨长链非编码RNA XLOC_015548基因敲减或过表达后C2C12小鼠成肌细胞中目的基因及成肌分化因子的表达情况。构建XLOC_015548基因编辑成肌细胞模型,为今后进一步实验提供基础。方法:根据RNA测序结果得出相关序列,拟构建XLOC_015548敲低及过表达慢病毒载体,并对C2C12成肌细胞系进行转染,制备出XLOC_015548基因编辑成肌细胞模型。使用荧光显微镜观察慢病毒感染细胞后绿色荧光蛋白质的表达。当XLOC_015548被敲除或过表达后,采用RT-qPCR及Western Blot检测XLOC_015548及成肌相关基因的表达量。结果:采用1、2、5、10、20、30的梯度感染复数(MOI)对成肌细胞进行转染,经嘌呤霉素筛选后,成功构建以MOI为20感染条件的XLOC_015548基因编辑成肌细胞模型。利用RT-qPCR初步检测出过表达XLOC_015548时,肌源性分化因子Myod的表达量升高,敲低XLOC_015548时则得到相反的结果。Western Blot实验提示过表达XLOC_015548可以提高Myod、Myogenin蛋白表达量,敲低后则得到相反的结果。结论:本研究构建了一种新的长链非编码调节因子XLOC_015548的基因编辑成肌细胞模型,初步验证了各组细胞模型中XLOC_015548的表达量,并探究其表达量与肌源性分化因子的相关性,该细胞模型可用于后续对失神经肌萎缩等骨科相关疾病的基础研究。

关键词：长链非编码RNA 成肌细胞分化慢病毒 RNA测序

软骨细胞中SIRT1基因敲减后作用状态不明确信号通路及对相关疾病或功能的影响

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中国组织工程研究 2024年第20期28卷 3123-3129页

作者：叶海明曾晖杨琪张耕翁鉴于斐北京大学深圳医院骨关节科广东省深圳市518036 骨科生物材料国家地方联合工程研究中心广东省深圳市518036 深圳市骨科疾病与生物材料研究重点实验室广东省深圳市518036 北京大学深圳医院超声影像科广东省深圳市518036

背景:沉默信息调节因子1以去乙酰化的方式调控软骨细胞中相关蛋白的功能,参与软骨细胞增殖分化,促进软骨缺损修复。目的:利用高通量技术筛选软骨细胞中沉默信息调节因子1基因敲减后作用状态不明确的信号通路以及产生变化的疾病或功能。... 详细信息

背景:沉默信息调节因子1以去乙酰化的方式调控软骨细胞中相关蛋白的功能,参与软骨细胞增殖分化,促进软骨缺损修复。目的:利用高通量技术筛选软骨细胞中沉默信息调节因子1基因敲减后作用状态不明确的信号通路以及产生变化的疾病或功能。方法:取处于对数生长期的小鼠ATDC5软骨细胞,分2组转染:对照组转染沉默信息调节因子1基因敲减阴性对照慢病毒,实验组转染沉默信息调节因子1基因敲减慢病毒。转染72 h后,利用小鼠基因表达谱芯片GeneChip®Mouse Genome 4302.0 Array检测mRNA的基因层面变化情况,应用生物信息学技术筛选激活或抑制不明确的信号通路以及这些信号通路相关因子,并分析疾病或功能模块的富集情况。结果与结论:①沉默信息调节因子1基因敲减后,小鼠ATDC5软骨细胞中激活或抑制状态不明确的信号通路有245条;②根据-log(P-value)排序选择排前20的激活或抑制状态不明确信号通路中的因子情况进行报道,包括IGFBP4、TGFBR1、CTGF、COL4A5、LHX2、IL1RL1、KLF6等;③根据-log(P-value)进行排序,细胞生长和增殖、生物体存活和细胞死亡与存活等14个疾病和功能密切相关模块明显变化;根据差异基因数量排序,生物体损伤和异常、癌症和细胞死亡与存活3个疾病和功能密切相关模块明显变化;根据-log(P-value)与差异基因数量综合排序,固有免疫应答这一疾病和功能模块被显著激活。

关键词：高通量测序沉默信息调节因子1 软骨缺损信号通路疾病或功能

2013—2022年浙江省台州市流感样病例监测的病原学分析

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上海预防医学 2024年第4期36卷 348-351页

作者：王紫怡沈伟伟王红珠翁坚台州市疾病预防控制中心浙江台州318000

【目的】分析2013—2022年浙江省台州市流感样病例(ILI)监测的病原学结果,及时了解流感病毒流行趋势,发现优势病毒株的变化规律,为该地区流感防控提供参考。【方法】收集24 183例ILI标本,采用实时荧光PCR方法对流感病毒核酸进行检测。... 详细信息

【目的】分析2013—2022年浙江省台州市流感样病例(ILI)监测的病原学结果,及时了解流感病毒流行趋势,发现优势病毒株的变化规律,为该地区流感防控提供参考。【方法】收集24 183例ILI标本,采用实时荧光PCR方法对流感病毒核酸进行检测。【结果】24 183例标本流感病毒总阳性率18.43%,其中构成比最高者为季H3亚型(占37.34%)。不同性别之间阳性率差异无统计学意义(χ^(2)=0.148,P=0.701)。不同年龄段之间阳性率差异有统计学意义(χ^(2)=496.626,P<0.001),其中25~59岁年龄组阳性率最高(22.56%)。ILI数量与流感阳性率呈正相关(r=0.592,P<0.001)。不同年份之间阳性率差异有统计学意义(χ^(2)=1 670.922,P<0.001),2013—2019年阳性率呈上升趋势(χ^(2)=30.559,P<0.001),2020年阳性率最低(0.04%),2021—2022年阳性率呈上升趋势(χ^(2)=304.465,P<0.001)。不同监测年度优势株不同。不同月份之间流感阳性率差异有统计学意义(χ^(2)=1 652.455,P<0.001),流感高峰主要集中在当年12月至次年3月和7—8月。【结论】2013—2022年台州地区流感病毒阳性率呈波浪型动态变化,不同年度流行优势株不同,呈交替流行特点,应继续加强流感病毒病原学监测和完善流感疫苗接种等防控措施。

关键词：流感样病例流感病毒病原学监测甲型流感病毒乙型流感病毒

General construction of revocable identity-based fully homomorphic signature

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Science China(Information Sciences) 2020年第3期63卷 266-271页

作者： Congge XIE jian weng Wei LU Lin HOU College of Information Science and Technology Jinan University School of Data and Computer Science Sun Yat-sen University

Dear editor,Fully homomorphic signature (FHS) is a cryptographic primitive and allows anyone to conduct any computations over signatures and generate a signature which, when verified, matches the calculated value of the computational run on the messages. An identity-based fully homomorphic signature (IBFHS) extended from an FHS can avoid

关键词： General construction of revocable identity-based fully homomorphic signature

Content subscribing mechanism in P2P streaming based on gamma distribution prediction

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第12期8卷 1983-1989页

作者： GUO Tong-qiang weng jian-guang ZHUANG Yue-ting School of Computer Science Zhejiang University Hangzhou 310027 China

P2P systems are categorized into tree-based and mesh-based systems according to their topologies. Mesh-based systems are considered more suitable for large-scale lnternet applications, but require optimization on latency issue. This paper proposes a content subscribing mechanism （CSM） to eliminate unnecessary time delays during data relaying. A node can send content data to its neighbors as soon as it receives the data segment. No additional time is taken during the interactive stages prior to data segment transmission of streaming content. CSM consists of three steps. First, every node records its historical segments latency, and adopts gamma distribution, which possesses powerful expression ability, to express latency statistics. Second, a node predicts subscribing success ratio of every neighbor by comparing the gamma distribution parameters of the node and its neighbors before selecting a neighbor node to subscribe a data segment. The above steps would not increase latency as they are executed before the data segments are ready at the neighbor nodes. Finally, the node, which was subscribed to, sends the subscribed data segment to the subscriber immediately when it has the data segment. Experiments show that CSM significantly reduces the content data transmission latency.

关键词： P2P streaming Gamma distribution Content subscribing mechanism (CSM)

钛合金切削中切屑形态与残余应力的仿真与实验研究

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机械科学与技术 2024年第4期43卷 619-627页

作者：庄可佳高金强翁剑张伟伟周胜强武汉理工大学机电工程学院武汉430070

钛合金作为航空工业的常用材料,其加工后的残余应力会严重影响到零件的使用寿命。本文针对钛合金加工建立了基于CEL方法的仿真模型,并搭建正交实验平台测量切屑形态和残余应力来验证模型的有效性。将所提模型与传统的拉格朗日方法和ALE... 详细信息

钛合金作为航空工业的常用材料,其加工后的残余应力会严重影响到零件的使用寿命。本文针对钛合金加工建立了基于CEL方法的仿真模型,并搭建正交实验平台测量切屑形态和残余应力来验证模型的有效性。将所提模型与传统的拉格朗日方法和ALE方法进行比较,结果表明CEL方法虽然耗时较长但是预测结果更加准确并且不产生网格畸变,综合性能最优。最后基于所提方法探究不同进给量和刃口半径影响下的切屑形态和加工表面残余应力。结果表明,随着进给量和刃口半径的增大,切屑锯齿化程度和等效切屑厚度增大,表面残余应力随着进给量和刃口半径的增大变得更压。

关键词：钛合金 CEL仿真切屑形态残余应力