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Cryoballoon ablation of persistent atrial fibrillation for de novo pulmonary vein isolation:a single-center follow-up study

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Journal of Geriatric Cardiology 2022年第10期19卷 725-733页

作者： Zhong-Jing CAO Xiao-Gang GUO Qi SUN Yan-Qiao CHEN Hai-Yang XIE jian-du YANG Hui-Qiang WEI Jia-Hui LI jian MA Department of Cardiology Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalSchool of Medicine UESTCChengduChina State Key Laboratory of Cardiovascular Disease Arrhythmia CenterFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial People’s HospitalGuangdong Academy of Medical ScienceGuangzhouChina

BACKGROUND Pulmonary vein isolation(PVI)alone for persistent atrial fibrillation(PersAF)remains *** characteristics of cryoballoon ablation(CBA)to treat PersAF and the blanking period recurrence are *** This study retrospectively analyzed patients with PersAF undergoing second-generation CBA for de novo *** post-procedural efficacy and survival analysis were compared between patients with different PersAF *** multivariate Cox regression analysis was used to detect the risk factors for *** and long-term recurrence were analyzed relative to each *** A total of 329 patients were enrolled,with a median PersAF duration of 4.0 months(interquartile range:2.0–12.0 months);257 patients(78.1%)were ***-Meier analysis of freedom from atrial fibrillation recurrence at 12,24,and 30 months showed 71.0%,58.5%,and 54.9%,*** PersAF had a relatively favorable survival rate and a narrow P-wave duration of restoring sinus rhythm compared with that of PersAF lasting more than three months(Pduration and left atrial anteroposterior diameter≥42 mm were the risk factors for atrial fibrillation recurrence after CBA[hazard ratio(HR)=1.89,95%CI:1.01–1.4,P=0.042;HR=3.6,95%CI:2.4–5.4,Pduration and left atrial size were risk factors for atrial fibrillation recurrence after *** period recurrence was associated with long-term recurrence.

关键词： balloon fibrillation atrial

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Overexpression of a Glycosyltransferase Gene from a Metabolically Poly-Resistant Beckmannia syzigachne Population Alters Growth and Confers Herbicide Resistance to Brachypodium distachyon

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Phyton-International Journal of Experimental Botany 2022年第4期91卷 761-772页

作者： Yizhao Huang Nannan Li Deya Wang jian du Weitang Liu Jinxin Wang Wei Li College of Food Science and Pharmaceutical Engineering Zaozhuang UniversityZaozhuang277160China Institute of Apicultural Research Chinese Academy of Agricultural SciencesBeijing100093China Key Laboratory of Pesticide Toxicology and Application Technique College of Plant ProtectionShandong Agricultural UniversityTai’an271018China College of Life Sciences Zaozhuang UniversityZaozhuang277160China

Beckmannia syzigachne is a noxious weed for rice-wheat rotations in *** ***(AH-02)population evolved metabolic resistance to fenoxaprop-P-ethyl and *** investigate the function of GT73C1 in this population,the GT73C1 gene was amplified by reverse transcription-polymerase chain reaction,and the sequence was 100%consistent with the transcriptome *** phylogenetic tree was displayed and annotated using FigTree *** plant overexpression vector of GT73C1 gene was constructed and used to transform Brachypodium distachyon ***,the expression of GT73C1 was significantly induced by fenoxaprop-P-ethyl and mesosulfuron-methyl,which was consistent with the findings from the whole plant *** results indicate that GT73C1 is closely related to the metabolic resistance of ***.

关键词： Beckmannia syzigachne GT73C1 gene phylogenetic analyses Brachypodium distachyon genetic transformation

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Current State and Challenges of Rehabilitation Needs Among Elderly-China,1990-2019

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China CDC weekly 2022年第39期4卷 871-874,I0003,I0004页

作者： Xin Guo Jiakang Huo Wanwei Dai Zhongyan Wang jian du Xiaoying Zheng Erdan Dong Department of Cardiology and Institute of Vascular Medicine Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesKey Laboratory of Molecular Cardiovascular ScienceMinistry of EducationBeijing Key Laboratory of Cardiovascular Receptors ResearchResearch Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular DiseasesChinese Academy of Medical SciencesHaihe Laboratory of Cell EcosystemBeijingChina Personnel Department Peking University Third HospitalBeijingChina Office of Academic Research Peking University Third HospitalBeijingChina Research Center of Population Health and Social Development University of Health and Rehabilitation Sciences/Soft Science Research Base of Public Policy on Population Health in Shandong ProvinceQingdao CityShandong ProvinceChina National Institute of Health Data Science Peking UniversityBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina APEC Health Science Academy Peking UniversityBeijingChina Institute of Cardiovascular Sciences Peking UniversityBeijingChina

Summary What is already known about this topic?Rehabilitation is an essential part of achieving health for all,whereas the estimates of rehabilitation needs,especially for elderly individuals in China,are not *** is added by this report?Compared with 1990,the prevalence and years of life lived with disability for health conditions in need of rehabilitation in China increased by 71.3%and 77.0%in 2019,respectively,at a rate much higher than the global *** are the implications for public health practices?This study mainly presents scientific data and a systematic analysis of the current state and challenges of rehabilitation needs for elderly individuals(aged 60 and above)in China based on the World Health Organization Rehabilitation Need Estimator.

关键词： rehabilitation Rehabilitation elderly

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Coupled extension and thickness-twist vibrations of lateral field excited AT-cut quartz plates

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Acta Mechanica Sinica 2014年第1期30卷 67-72页

作者： Ting-Feng Ma Rong-Xing Wu Ji Wang jian-Ke du Li-Li Yuan Fa-Peng Yu Chao Xie Piezoelectric Device Laboratory School of Mechanical Engineering & MechanicsNingbo University Department of Architectural Engineering Ningbo Polytechnic State Key Lab of Crystal Materials and Institute of Crystal Materials Shandong University

In this paper, the coupled extension and thickness- twist vibrations are studied for AT-cut quartz plates under Lateral Field Excitation （LFE） with variations along the x1- direction. Mindlin＇s two-dimensional equations are used for anisotropic crystal plates. Both free and electrically forced vibrations are considered. Important vibration characteristics are obtained, including dispersion relations, frequency spectra, and motional capacitances. It is shown that, to avoid the effects of the couplings between extension and thickness-twist vibrations, a series of discrete values of the length/thickness ratio of the crystal plate need to be excluded. The results are of fundamental significance for the design of LFE resonators and sensors.

关键词： Lateral field excitation - Resonators Quartz Thickness-twist vibrations

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Study on Catalytic Cracking of VGO Derived from Kazakhstan-Russian Mixed Crude

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China Petroleum Processing & Petrochemical Technology 2006年第2期8卷 33-39页

作者： duan Yongsheng Dong Yuancheng Wei Gangling Wang jian (du Shanzi Petrochemical Company, du Shanzi, 833600) du Shanzi Petrochemical Company Du Shanzi 833600 China

The study on options for catalytic cracking of VGO derived from the Kazakhstan-Russian mixed crude was carried out in a small-scale riser FCC unit. The influence of several catalysts and the LCC-A additive for increasing propylene yield on the distribution and quality of FCC products was analyzed. This article sets forth the possible issues arising from processing the Kazakhstan-Russian mixed crude in FCC unit and the response measures to be adopted.

关键词： VGO derived from the Kazakhstan-Russian mixed crude catalytic cracking response measure

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Studies on the Growth Habits and Characteristics of Two Polyploid Indica-Japonica Hybrid Rice with Powerful Heterosis

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Agricultural Sciences in China 2007年第3期6卷 265-274页

作者： SONG Zhao-jian du Chao-qun DAI Bing-cheng CHEN Dong-ling CHEN jian-guo CAI De-tian College of Life Science Hubei University Wuhan 430062 P.R.China

Based on a series of polyploid indica-japonica hybrid plant lines obtained from a new breeding strategy of using double predominance of wide cross and polyploidization to breed super flee, two polyploid indica-japonica hybrids, PSR073 and PSR120 were studied in their growth periods to show the powerful heterosis in a larger scale and to study the characteristics of polyploid indica-japonica hybrids more elaborately. The leaf age, tiller growth, flowering habits, and agronomic traits of them were observed to analyze their growth habits and characteristics. The results showed that *** traits of PSR073 and PSR120, such as the plant height, panicle length, grain length, grain width, and 1000-grain weight, all acquired obvious predominance of polyploidy, and that the seed setting rate was more than 83%. No significant difference was observed between the two tetraploids and common diploids in the leaf age, tiller growth, and flowering habits. It was concluded that the characteristics of the two powerful heterosis polyploid hybrids were different from those of the polyploid rice reported earlier. Wide cross and polyploidization had no negative effects on their growth habits and characteristics; on the contrary these had powerful heterosis. This had provided theoretic and practical evidences for their application to agricultural production.

关键词： polyploid indica-japonica hybrids growth habits and characteristics heterosis seed setting rate

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Reference genes for quantitative real-time PCR analysis and quantitative expression of P5CS in Agropyron mongolicum under drought stress

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Journal of Integrative Agriculture 2016年第9期15卷 2097-2104页

作者： TIAN Qing-song WANG Shu-yan du jian-cai WU Zhi-juan LI Xiao-quan HAN Bing Institute of Grassland Research Chinese Academy of Agricultural Sciences Hohhot 010010 P.R. China gronomy College Inner Mongolia Agricultural University Hohhot 010010 P.R. China College of Life Science Inner Mongolia Agricultural University Hohhot 010010 P.R. China

Reference genes, stably expressing in different tissues and cells, are commonly used as the references in expression analysis. Selecting the optimum reference gene is crucial to the success of experiments. In this study, the expression stabilities of nine common reference genes, including ACT2, 18 S r RNA, APRT, EF-1α, RNA POL II, TUBα, TUBβ, GAPDH and TLF of Agropyron mongolicum, were studied under drought condition. Among them, 18 S r RNA was found to be the most optimum reference gene under drought stress by the analyzing of ge Norm and Norm Finder software. Quantitative expression levels of P5 CS using 18 S r RNA as the reference gene, and proline contents under drought stress in A. mongolicum were further operated, and we found the expression level of P5 CS gene and proline content had a significantly positive relationship（R^2=0.7763, P〈0.05）. This study established and validated 18 S r RNA as the reference genes in A. mongolicum under drought stress, providing a powerful tool for the quantitative expression analysis of drought genes in A. mongolicum.

关键词： reference genes quantitative real-time PCR drought stress proline pyrroline-5-carboxylic acid synthetase Agropyron mongolicum

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Discovery of leaf region and time point related modules and genes in maize(Zea mays L.)leaves by Weighted Gene Co-expression Network analysis(WGCNA)of gene expression profiles of carbon metabolism

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Journal of Integrative Agriculture 2019年第2期18卷 350-360页

作者： WANG Jing-lu ZHANG Ying PAN Xiao-di du jian-jun MA Li-ming GUO Xin-yu Beijing Key Lab of Digital Plant/Beijing Research Center for Information Technology in Agriculture/National Engineering Research Center for Information Technology in Agriculture/Beijing Academy of Agriculture and Forestry Sciences Beijing 100097P.R.China

Maize(Zea mays L.) yield depends not only on the conversion and accumulation of carbohydrates in kernels, but also on the supply of carbohydrates by leaves. However, the carbon metabolism process in leaves can vary across different leaf regions and during the day and night. Hence, we used Weighted Gene Co-expression Network analysis(WGCNA) with the gene expression profiles of carbon metabolism to identify the modules and genes that may associate with particular regions in a leaf and time of day. There were a total of 45 samples of maize leaves that were taken from three different regions of a growing maize leaf at five time points. Robust Multi-array Average analysis was used to pre-process the raw data of GSE85963(accession number), and quality control of data was based on Pearson correlation coefficients. We obtained eight co-expression network modules. The modules with the highest significance of association with LeafRegion and TimePoint were selected. Functional enrichment and gene-gene interaction analyses were conducted to acquire the hub genes and pathways in these significant modules. These results can support the findings of similar studies by providing evidence of potential module genes and enriched pathways associated with leaf development in maize.

关键词： WGCNA maize leaf gene expression gene modules pathways

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P_(4k-1)-factorization of bipartite multigraphs

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Science China Mathematics 2006年第7期49卷 961-970页

作者： WANG jian & du Beiliang Nantong Vocational College, Nantong 226007, China Department of Mathematics, Suzhou University, Suzhou 215006, China Vocational College Nantong China Department of Mathematics Suzhou University Suzhou China

LetλKm,n be a bipartite multigraph with two partite sets having m and n vertices, respectively. A Pν-factorization ofλKm,n is a set of edge-disjoint Pν-factors ofλKm,n which partition the set of edges ofλKm,n. Whenνis an even number, Ushio, Wang and the second author of the paper gave a necessary and sufficient condition for the existence of a Pν-factorization ofλKm,n. When v is an odd number, we proposed a conjecture. However, up to now we only know that the conjecture is true forν= 3. In this paper we will show that the conjecture is true whenν= 4k-1. That is, we shall prove that a necessary and sufficient condition for the existence of a P4k-1-factorization ofλKm,n is (1) (2k-1)m≤2kn, (2) (2k-1)n≤2km, (3)m + n = 0 (mod 4k-1), (4)λ(4k-1)mn/[2(2k-1)(m + n)] is an integer.

关键词： bipartite multigraph, factor, factorization.

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Application and progress of the detection technologies in hepatocellular carcinoma

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Genes & Diseases 2023年第5期10卷 1857-1869页

作者： Qi Yan Yuan-song Sun Ran An Fang Liu Qi Fang Zhen Wang Tao Xu Lijian Chen jian du School of Basic Medical Sciences Anhui Medical UniversityHefeiAnhui 230032China Department of Emergency Surgery The Second Hospital of Anhui Medical UniversityHefeiAnhui 230032China Department of Anesthesiology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230032China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative DrugsSchool of PharmacyHefeiAnhui 230032China Institute for Liver Diseases of Anhui Medical University Anhui Medical UniversityHefeiAnhui 230032China

Hepatocellular carcinoma(HCC)has a very high incidence and fatality rate,and in most cases,it is already at an advanced stage when ***,early prevention and detection of HCC are two of the most effective ***,the methods recommended in the practice guidelines for the detection of HCC cannot guarantee high sensitivity and specificity except for the liver biopsy,which is known as the“gold standard”.In this review,we divided the detection of HCC into pre-treatment diagnosis and post-treatment monitoring,and found that in addition to the traditional imaging detection and liver biopsy,alpha fetoprotein(AFP),lens culinaris-agglutinin-reactive fraction of AFP(AFP-L3),protein induced by vitamin K absence or antagonist-II(PIVKA-II)and other biomarkers are excellent biomarkers for HCC,especially when they are combined *** notably,the emerging liquid biopsy shows great promise in detecting *** addition,lactic dehydrogenase(LDH),suppressor of cytokine signaling(SOCS)and other relevant biomarkers may become promising biomarkers for HCC post-treatment *** the detailed introduction of the diagnostic technology of HCC,we can have a detailed understanding of its development process and then obtain some enlightenment from the diagnosis,to improve the diagnostic rate of HCC and reduce its mortality.

关键词： HCC Invasive diagnosis Minimally invasive diagnosis Noninvasive diagnosis Prognostic monitoring

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