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大粒径透水性沥青混合料水稳定性能对比研究

建筑材料学报 2009年第4期12卷 493-496页

作者：房建果郭忠印王松根同济大学交通运输学院上海200092 山东省交通厅公路局山东济南250002

针对不同沥青用量的大粒径透水性沥青混合料(LSPM-30)进行了常规的浸水马歇尔试验、真空饱水马歇尔试验及冻融劈裂试验,结果表明:存在一个最佳的沥青用量,该沥青用量使得LSPM-30沥青混合料的残留稳定度和残留强度比达到最大值;浸水马歇... 详细信息

针对不同沥青用量的大粒径透水性沥青混合料(LSPM-30)进行了常规的浸水马歇尔试验、真空饱水马歇尔试验及冻融劈裂试验,结果表明:存在一个最佳的沥青用量,该沥青用量使得LSPM-30沥青混合料的残留稳定度和残留强度比达到最大值;浸水马歇尔试验和冻融劈裂试验对于评价LSPM-30沥青混合料的水稳定性有一定局限性.采用汉堡车辙试验对比分析了LSPM-30,OGFC-16,SMA-13,AC-25I这4种沥青混合料的水稳定性,结果表明:LSPM-30,OGFC-16,SMA-13这些骨架嵌挤型的沥青混合料有较好的水稳定性;汉堡车辙试验较适于用来评价LSPM-30的水稳定性.

关键词：大粒径透水性沥青混合料浸水马歇尔试验真空饱水马歇尔试验冻融劈裂试验汉堡车辙试验水稳定性

单侧完全性唇腭裂患者上颌尖牙长度的锥形束CT测量及其他相关统计分析

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华西口腔医学杂志 2011年第2期29卷 161-163,167页

作者：李放王建国南开大学附属天津市口腔医院正畸科天津300041

目的使用锥形束CT(CBCT)测量单侧完全性唇腭裂患者的裂隙侧与非裂隙侧上颌尖牙的长度,包括尖牙的全长、冠长、根长及冠根比,比较两侧的差异,并同时对裂隙附近的其他牙齿异常进行统计。方法对20例单侧完全性唇腭裂患者进行CBCT扫描,经配... 详细信息

目的使用锥形束CT(CBCT)测量单侧完全性唇腭裂患者的裂隙侧与非裂隙侧上颌尖牙的长度,包括尖牙的全长、冠长、根长及冠根比,比较两侧的差异,并同时对裂隙附近的其他牙齿异常进行统计。方法对20例单侧完全性唇腭裂患者进行CBCT扫描,经配套三维重建工作站进行处理后形成清晰的头颅三维重建图像,沿上颌两侧尖牙长轴获得牙齿的断层图像,测量上颌尖牙的全长、冠长及根长,对裂隙侧和非裂隙侧上颌尖牙的全长、冠长、根长及冠根比进行配对t检验,并对裂隙区其他前牙异常及裂隙部位进行记录。结果单侧完全性唇腭裂患者的裂隙侧与非裂隙侧上颌尖牙全长、根长及冠根比的差异均有统计学意义(P0.05)。裂隙区侧切牙异常20例(100%)。结论单侧完全性唇腭裂患者裂隙侧上颌尖牙的长度较非裂隙侧短,尤以根长较明显。裂隙区的牙齿较易发生异常,特别是侧切牙发生异常率高。

关键词：单侧完全性唇腭裂牙槽嵴裂上颌尖牙锥形束CT

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斜拉桥-EMD系统智能模型及控制仿真研究

系统仿真学报 2010年第7期22卷 1632-1635页

作者：何敏王建国合肥工业大学土木与水利工程学院合肥230009

基于智能算法建立斜拉桥-EMD控制系统的智能模型,并对其进行了智能主动控制的数值仿真。首先利用遗传算法优化BP神经网络的权值和阈值,由仿真数据建立斜拉桥-EMD控制系统的智能模型,代替传统的有限元模型对桥梁结构进行动力分析;然后综... 详细信息

基于智能算法建立斜拉桥-EMD控制系统的智能模型,并对其进行了智能主动控制的数值仿真。首先利用遗传算法优化BP神经网络的权值和阈值,由仿真数据建立斜拉桥-EMD控制系统的智能模型,代替传统的有限元模型对桥梁结构进行动力分析;然后综合模糊逻辑推理和神经网络理论设计智能主动控制策略,对智能模型进行智能主动控制,数值仿真结果表明:此方法振动控制效果良好,可以有效抑制桥梁结构地震波激励下的结构动力反应。

关键词： EMD系统斜拉桥智能模型智能控制 GA-BP神经网络模糊神经网络

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导叶式旋风管排气管内流动减阻的试验研究

中国石油大学学报（自然科学版） 2007年第5期31卷 83-86,90页

作者：杨建国郭颖王建军马庆磊金有海山东石大科技集团山东东营257061 中国石油大学机电工程学院山东东营257061

通过对导叶式旋风管内流动参数的测量分析,发现排气管内气流旋转强度高,并存在'滞流'、'倒流'及逆压梯度等无益于颗粒分离的流动状态,造成排气管内压力损失约占旋风管总压降的22%。在排气管内安装框形结构后,可有效削弱和抑制上述耗能流... 详细信息

通过对导叶式旋风管内流动参数的测量分析,发现排气管内气流旋转强度高,并存在'滞流'、'倒流'及逆压梯度等无益于颗粒分离的流动状态,造成排气管内压力损失约占旋风管总压降的22%。在排气管内安装框形结构后,可有效削弱和抑制上述耗能流动,在保证分离效率基本不变的前提下,使旋风管减阻幅度达到9%。

关键词：旋风管排气管流场减阻

晾制时间对上部叶烘烤过程生理特性和烟叶品质的影响

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江西农业学报 2024年第4期36卷 23-28页

作者：池国胜辛永康刘智奇李奎李运有叶礼霆李炳兵江长建王景周阳南平市烟草公司光泽分公司福建光泽354100 河南农业大学烟草学院/烟草行业烟草栽培重点实验室/国家烟草栽培生理生化研究基地河南郑州450046 陕西中烟工业有限责任公司原料采购中心陕西宝鸡721013

为探究晾制时间对上部叶烘烤过程生理特性和烤后烟叶品质的影响,以K326的上部叶为试验材料,通过先晾后烤的方法,以当地常规烘烤(无晾制)模式为对照(CK),设置了T_(1)(晾制24 h)、T_(2)(晾制36 h)2种晾制时间,探究了先晾后烤处理对烟叶烘... 详细信息

为探究晾制时间对上部叶烘烤过程生理特性和烤后烟叶品质的影响,以K326的上部叶为试验材料,通过先晾后烤的方法,以当地常规烘烤(无晾制)模式为对照(CK),设置了T_(1)(晾制24 h)、T_(2)(晾制36 h)2种晾制时间,探究了先晾后烤处理对烟叶烘烤工艺、烘烤过程烟叶的生理特性及烤后烟化学成分和香气成分的影响,得出最适宜的晾制时间和烘烤工艺。结果表明:与常规烘烤相比,T_(1)、T_(2)处理在烘烤前含水率分别下降了2.81、3.03个百分点;T_(2)处理烘烤总用时下降了22 h,均价提高了4.13%;与CK相比,T_(2)处理烤后烟叶烟碱和总氮含量分别显著降低了1.16、0.35个百分点;T_(1)、T_(2)处理棕色化反应产物、苯丙氨酸裂解产物、类胡萝卜素降解产物总量均增加,T_(2)处理的香气总量提升了6.40%。综上所述,南平地区K326上部叶经过先晾后烤处理后烘烤用时缩短、经济性状好、烤后烟叶总体质量符合上部叶增效提质要求,其中T_(2)处理的效果整体表现最优。

关键词：烤烟上部叶先晾后烤变黄期含水率化学成分香气成分

Total Synthesis of Phakellistatin 13 by Solution Method

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Chinese Chemical Letters 2006年第8期17卷 995-998页

作者： Qing Feng jianG You Jun ZHOU jian Zhong YAO Jia guo LU Ju ZHU Chun Quan SHENG Can Hui ZHENG Bing YAO Department of Medicinal Chemistry School of Pharmacy Second Military Medical University Shanghai 200433

Phakellistatin 13 is a good antitumor lead compound isolated from halobios. It was synthesized first time by solution method in combination of stepwise coupling and segment condensation. Final deprotection and cyclization were achieved according to our designed method, which was different from the reported process. The spectral data of synthetic product is consisted with literatureal data of natural product. Total synthesis of phakellistatin 13 is a significant achievement to further study of its derivatives and developing novel antitumor drugs.

关键词： Phakellistatin 13 solution-phase synthesis cyclopeptide.

Study on the existing state of chlortetracycline in Streptomyces aureofacines

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中国抗生素杂志 2002年第2期27卷 92-96,100页

作者： Meng Chun guo Yang－hao 等 StateKeyLaboratoryofBioreactor ECUSTShanghai200237 DepartmentofBiotechnologyangFoodScience FuzhouUniversityFuzhou350002

Most chlortetracycline (CTC) which was produced in fermentation process or was added into solution diffused into mycelium of Streptomyces aureofacins while seldom did into other microorganism cells. According to results of mycelium disruption of S. aureofaciens, CTC did not dissolve in cytoplasm of S. aureofaciens but was absorbed by intracellular components. Variation of pH had obvious effects on CTC absorption of *** cells, and more than 95% CTC was absorbed by mycelium at physiological conditions while all dissolved in solution when of pH value is lower than 1.4. From body solutions into cell, CTC transport was passive diffusion. Special absorption of CTC in mycelium of S. aureofaciens may be one important factor that S. aureofaciens had such potent resistance to CTC.

关键词：金霉素金霉素链球菌被动扩散特异性吸收

Identification of Graves’ophthalmology by laser-induced breakdown spectroscopy combined with machine learning method

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Frontiers of Optoelectronics 2021年第3期14卷 321-328页

作者： Jingjing LI Feng CHEN Guangqian HUANG Siyu ZHANG Weiliang wang Yun TANG Yanwu CHU jian YAO Lianbo guo Fagang jianG Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Department of Ophthalmology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China School of Remote Sensing and Information Engineering Wuhan UniversityWuhan 430079China

Diagnosis of the Graves’ophthalmology remains a significant *** identified between Graves’ophthalmology tissues and healthy controls by using laser-induced breakdown spectroscopy(LIBS)combined with machine learning *** this work,the paraffin-embedded samples of the Graves’ophthalmology were prepared for LIBS spectra *** metallic elements(Na,K,Al,Ca),non-metallic element(O)and molecular bands((C-N),(C-O))were selected for diagnosing Graves’*** selected spectral lines were inputted into the supervised classification methods including linear discriminant analysis(LDA),support vector machine(SVM),k-nearest neighbor(ANN),and generalized regression neural network(GRNN),*** results showed that the predicted accuracy rates of LDA,SVM,ANN,GRNN were 76.33%,96.28%,96.56%,and 96.33%,*** sensitivity of four models were 75.89%,93.78%,96.78%,and 96.67%,*** specificity of four models were 76.78%,98.78%,96.33%,and 96.00%,*** demonstrated that LIBS assisted with a nonlinear model can be used to identify Graves’ophthalmopathy with a higher rate of *** ANN had the best performance by comparing the three nonlinear ***,LIBS combined with machine learning method can be an effective way to discriminate Graves’ophthalmology.

关键词： Graves’ophthalmology laser-induced breakdown spectroscopy(LIBS) linear discriminant analysis(LDA) support vector machine(SVM) k-nearest neighbor(kNN) generalized regression neural network(GRNN)

Nuclear factor-kappaB activation on the reactive oxygen species in acute necrotizing pancreatitic rats

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World Journal of Gastroenterology 2005年第27期11卷 4277-4280页

作者： Jin Long Na Song Xi-Ping Liu Ke-jian guo Ren-Xuan guo Department of Surgery The First Affiliated Hospital China Medical University Shenyang 110001 Liaoning Province China

AIM： To investigate the potential role of nuclear factor kappa-B （NF-κB） activation on the reactive oxygen species in rat acute necrotizing pancreatitis （ANP） and to assess the effect of pyrrolidine dithiocarbamate （PDTC, an inhibitor of NF-κB）.METHODS： Rat ANP model was established by retrograde injection of 5% sodium taurocholate into biliopancreatic duct. Rats were randomly assigned to three groups （10 rats each）： Control group, ANP group and PDTC group. At the 6^th of the model, the changes of the serum amylase,nitric oxide （NO）, malondialdehyde （MDA）, superoxide dismutase （SOD） and pancreatic morphological damage were observed. The expressions of inducible nitric oxide （iNOS） were observed by SP immunohistochemistry. And bhe expressions of NF-κB p65 subunit mRNA were observed by hybridization in ***： Serum amylase and NO level decreased significantly in ANP group as compared with PDTC administrated group [（7 170.40＋1 308.63） U/L vs（4 074.10＋1 719.78） U/L,P〈0.05], [（76.95±9.04） μmol/L vs （65.18±9.02） μmol/L,P〈0.05] respectively. MDA in both ANP and PDTC group rose significantly over that in control group [（9.88＋1.52）nmol/L, （8.60±1.41） nmol/L, vs （6.04：hl.78） nmol/L,P〈0.05], while there was no significant difference between them. SOD levels in both ANP and PDTC group underwent a significant decrease as compared with that in control[（3 214.59±297.74） NU/mL, （3 260.62±229.44） NU/mL,vs（3 977.80＋309.09） NU/mL, P〈0.05], but there was no significant difference between them. Though they were still higher bhan those in Control group, pancreas destruction was slighter in PDTC group, iNOS expression and NF-κB p65 subunit mRNA expression were lower in PDTC group as compared with ANP ***： We conclude that correlation among NF-κB activation, serum amylase, reactive oxygen species level and tissue damage suggests a key role of NF-κB in the pathogenesis of ANP. Inhibition of NF-κB activation may reverse the pancreatic damage of rat ANP and the production

关键词： Pancreatitis Acute necrotizing Nuclear factorkappaB Reactive oxygen species