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Incidence characteristics of testicular microlithiasis and its association with risk of primary testicular tumors in children: a systematic review and meta-analysis

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World Journal of Pediatrics 2020年第6期16卷 585-597页

作者： Cheng-Jun Yu jian-Dong Lu Jie Zhao Yi Wei Tian-Xin Zhao Tao Lin •Da-Wei He Sheng-De wu Guang-Hui Wei Department of Urology Children's Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering ChongqingChina National Clinical Research Center for Child Health and Disorders ChongqingChina Chongqing Key Laboratory of Pediatrics Chongqing Room 806.Kejiao Building(No.6)No.136.Zhongshan 2nd RoadYuzhong DistrictChongqing.China China International Science and Technology Cooperation Base of Child Development and Critical Disorders ChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders ChongqingChina

Background To systematically evaluate the incidence characteristics of testicular microlithiasis(TM)in children and its association with primary testicular tumors(PTT).Methods A systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis(PRISMA)statement.A priori protocol was registered in the PROSPERO database(CRD42018111119),and a literature search of all relevant studies published until February 2019 was ***,retrospective cohort,or cross-sectional studies containing ultrasonography(US)data on the incidence of TM or the association between TM and PTT were eligible for *** Of the 102 identified articles,18 studies involving 58,195 children were included in the final *** overall incidence of TM in children with additional risk factors for FTT was 2.1%.In children,the proportion of left TM in unilateral cases was 55.7%,the frequency of bilateral TM was 69.0%,and proportion of classic TM was 71.8%[95%confidence interval(Cl)62.4-81.1%,P=0.0,72=0.0%].About 93.5%of TM remained unchanged,and newly detected PTT rate was very low(4/296)during *** overall risk ratio of TM in children with a concurrent diagnosis of PTT was 15.46(95%Cl 6.93-34.47,P<0.00001).Conclusions The incidence of TM in children is highly ***,TM is usually bilateral,of the classic type,and remains stable or unchanged at *** patients with TM and contributing factors for PTT have an increased risk for PTT;however,there is no evidence to support mandatory US surveillance of children with TM.

关键词： Children Incidence Primary testicular tumors Testicular microlithiasis

Enhanced figure of merit for famatinite Cu_(3)SbSe_(4)via band structure tuning and hierarchical architecture

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Journal of Materiomics 2023年第6期9卷 1263-1272页

作者： Lijun Zhao Haolin Ye Xinmeng wu jian Yang Lihua Yu Zhongqi Shi Shahid Hussain Guanjun Qiao Junhua Xu Bangzhi Ge Li Wang Chongjian Zhou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang212100JiangsuChina State Key Laboratory of Solidification Processing Key Laboratory of Radiation Detection Materials and DevicesMinistry of Industry and Information TechnologyNorthwestern Polytechnical UniversityXi'an710072ShaanxiChina School of Materials Science and Engineering Jiangsu UniversityZhenjiang212013JiangsuChina State Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong UniversityXi'an710049ShaanxiChina

The p-type Te-free Cu_(3)SbSe_(4)with famatinite structure is a potential candidate for thermoelectric materials due to the low cost and eco-friendly constituent ***,its strong bipolar effect and high lattice thermal conductivity(klat)are the main challenges for its performance ***,we report a new strategy to enhance its figure of merit zT~0.86 at 673 K for Cu_(3)Sb_(0.95)Fe_(0.05)Se_(2.8)S_(1.2)via band structure tuning and hierarchical ***,S substituted Se atoms in lattice can widen the band gap to alleviate the bipolar ***,Fe doping in Sb site significantly increases the density of states,thus increasing the carrier effective mass,and obtaining a remarkably high Seebeck coefficient of~560 mV/K at 300 ***,the induced hierarchical architecture defects resulting in a minimum klat of~0.48 W·m^(-1)·K^(-1)at 673 ***,the improved Seebeck coefficient combined with low thermal conductivity leads to an enhanced zT.

关键词： Cu3SbSe4-Based materials Defects Band gap Thermoelectric properties Solid solution

Soil temperature estimation at different depths,using remotely-sensed data

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Journal of Integrative Agriculture 2020年第1期19卷 277-290页

作者： HUANG Ran HUANG jian-xi ZHANG Chao MA Hong-yuan ZHUO Wen CHEN Ying-yi ZHU De-hai Qingling wu Lamin R.MANSARAY College of Land Science and Technology China Agricultural University/Key Laboratory of Remote Sensing for Agri-hazardsMinistry of Agriculture and Rural Affairs/Key Laboratory for Agricultural Land QualityMinistry of Natural ResourcesBeijing 100083P.R.China College of Information&Electrical Engineering China Agricultural UniversityBeijing 100083P.R.China Department of Geography University College LondonLondon WC1E 6BTUK Department of Agro-meteorology and Geo-informatics Magbosi LandWater and Environment Research Centre(MLWERC)Sierra Leone Agricultural Research Institute(SLARI)Freetown PMB 1313Sierra Leone

Soil temperatures at different depths down the soil profile are important agro-meteorological indicators which are necessary for ecological modeling and precision agricultural activities. In this paper, using time series of soil temperature(ST) measured at different depths(0, 5, 10, 20, and 40 cm) at agro-meteorological stations in northern China as reference data, ST was estimated from land surface temperature(LST) and normalized difference vegetation index(NDVI) derived from AQUA/TERRA MODIS data, and solar declination(Ds) in univariate and multivariate linear regression models. Results showed that when daytime LST is used as predictor, the coefficient of determination(R^2) values decrease from the 0 cm layer to the 40 cm layer. Additionally, with the use of nighttime LST as predictor, the R^2 values were relatively higher at 5, 10 and 15 cm depths than those at 0, 20 and 40 cm depths. It is further observed that the multiple linear regression models for soil temperature estimation outperform the univariate linear regression models based on the root mean squared errors(RMSEs) and R^2. These results have demonstrated the potential of MODIS data in tandem with the Ds parameter for soil temperature estimation at the upper layers of the soil profile where plant roots grow in. To the best of our knowledge, this is the first attempt at the synergistic use of LST, NDVI and Ds for soil temperature estimation at different depths of the upper layers of the soil profile, representing a significant contribution to soil remote sensing.

关键词： soil temperature land surface temperature normalized difference vegetation index solar declination

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新型透明黏土的配制及其基本特性研究

岩土工程学报 2020年第S1期42卷 141-145页

作者：吴跃东陈明建周云峰刘坚河海大学岩土力学与堤坝工程教育部重点实验室江苏南京210098 河海大学岩土工程科学研究所江苏南京210098

人工合成透明土是研究土体内部的变形及渗流情况的良好工具,传统透明土多针对砂土,且在量化透明度方面尚未形成统一的评价系统。针对上述问题,提出一种新型透明黏土——AVC透明土的配制方法,和一种透明土的透明度量化评价方法,并用该方... 详细信息

人工合成透明土是研究土体内部的变形及渗流情况的良好工具,传统透明土多针对砂土,且在量化透明度方面尚未形成统一的评价系统。针对上述问题,提出一种新型透明黏土——AVC透明土的配制方法,和一种透明土的透明度量化评价方法,并用该方法对比分析AVC透明土与传统透明土的透明度;开展固结试验与微型十字板剪切试验,得到该透明土的压缩固结特性与强度影响因素。试验结果表明:AVC透明黏土具有250mm可视厚度,透明度优于传统透明土;压缩特性与天然黏土十分相似,固结系数与淤泥相似;2.5%浓度AVC透明土比4.5%浓度LAPONITERD透明土的峰值强度更高。

关键词：透明黏土配制透明度强度压缩特性

毛竹林大小年经营模式对土壤有机碳组分含量的影响

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世界竹藤通讯 2024年第4期22卷 29-34页

作者：冷利松周熠董婉君吴兆维张小平张健万众安吉县林业局浙江安吉313300 浙江省安吉县竹产业协会浙江安吉313000 国家林业和草原局竹子研究开发中心/竹林生态与资源利用国家林业和草原局重点实验室杭州310012

毛竹林通常采用大小年经营,以实现更高的生产力。然而,有关大小年经营对土壤碳固存的影响知之甚少。比较研究了大年和小年毛竹林的土壤养分含量、有机碳组分。结果发现,与大年毛竹林相比,小年毛竹林土壤有机碳(TOC)、微生物量碳(MBC)、... 详细信息

毛竹林通常采用大小年经营,以实现更高的生产力。然而,有关大小年经营对土壤碳固存的影响知之甚少。比较研究了大年和小年毛竹林的土壤养分含量、有机碳组分。结果发现,与大年毛竹林相比,小年毛竹林土壤有机碳(TOC)、微生物量碳(MBC)、易可溶性有机碳(DOC)、易氧化有机碳(EOC)、铁铝结合态有机碳[Fe(Al)-SOC]和钙结合态有机碳(Ca-SOC)含量以及碳库管理指数显著增加,而pH值、速效氮(NH_(4)-N+NO_(3)-N)和有效磷(AP)含量显著降低。相关性分析结果显示,土壤TOC、DOC、EOC、Ca-SOC与Fe(Al)-SOC与pH值、NO_(3)-N和AP呈显著负相关(P<0.05),与NH_(4)-N呈显著正相关(P<0.05)。研究结果表明,小年毛竹林提高了土壤有机碳及其组分的含量和碳库管理指数,可以弥补大年的碳和养分消耗,维持土壤固碳和保肥能力。

关键词：毛竹大小年土壤有机碳组分经营方式浙江安吉

The Arabidopsis NuA4 histone acetyltransferase complex is required for chlorophyll biosynthesis and photosynthesis

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Journal of Integrative Plant Biology 2022年第4期64卷 901-914页

作者： Jin-Xing Zhou Xiao-Min Su Si-Yao Zheng Chan-Juan wu Yin-Na Su Zhaodi jiang Lin Li She Chen Xin-jian He College of Life Sciences Beijing Normal UniversityBeijing 100091China National Institute of Biological Sciences Beijing 102206China Tsinghua Institute of Multidisciplinary Biomedical Research Tsinghua UniversityBeijing 100084China

Although two Enhancer of Polycomb-like proteins,EPL1 A and EPL1 B(EPL1 A/B),are known to be conserved and characteristic subunits of the Nu A4-type histone acetyltransferase complex in Arabidopsis thaliana,the biological function of EPL1 A/B and the mechanism by which EPL1 A/B function in the complex remain ***,we report that EPL1 A/B are required for the histone acetyltransferase activity of the Nu A4 complex on the nucleosomal histone H4 in vitro and for the enrichment of histone H4 K5 acetylation at thousands of protein-coding genes in *** results suggest that EPL1 A/B are required for linking the Nu A4 catalytic subunits HISTONE ACETYLTRANSFERASE OF THE MYST FAMILY 1(HAM1)and HAM2 with accessory subunits in the Nu A4 ***1 A/B function redundantly in regulating plant development especially in chlorophyll biosynthesis and *** EPL1 A/B-dependent transcription and H4 K5 Ac are enriched at genes involved in chlorophyll biosynthesis and *** also find that EAF6,another characteristic subunit of the Nu A4 complex,contributes to *** results suggest that the Arabidopsis Nu A4 complex components function as a whole to mediate histone acetylation and transcriptional activation specifically at light-responsive genes and are critical for photomorphogenesis.

关键词： chlorophyll EPL1A HAM1 histone acetyltransferase NuA4 photosynthesis transcription

2017、2022年青岛市市北区居民健康素养水平比较及其影响因素分析

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预防医学论坛 2024年第2期30卷 142-147页

作者：孟铃洁李玉华吴若男赵绪建辛乐忠青岛市市北区疾病预防控制中心健康教育科山东266011 青岛市市北区疾病预防控制中心

目的调查2017、2022年青岛市市北区居民的健康素养水平,比较两个年度居民的健康素养水平差异,并分析其影响因素。方法用《全国居民健康素养监测调查问卷》,按多阶段分层随机抽样法,于2017、2022年分别对青岛市市北区15~69岁常住居民进... 详细信息

目的调查2017、2022年青岛市市北区居民的健康素养水平,比较两个年度居民的健康素养水平差异,并分析其影响因素。方法用《全国居民健康素养监测调查问卷》,按多阶段分层随机抽样法,于2017、2022年分别对青岛市市北区15~69岁常住居民进行健康素养问卷调查,分析居民的健康素养水平,建立二分类logistic回归模型分析性别、年龄、文化程度等对居民健康素养水平的影响。结果2017年调查1515人,2022年调查911人。2017年居民的健康素养水平为21.30%,2022年为35.74%;35~44岁年龄居民的健康素养水平提升幅度大。2017、2022年居民的基本知识和理念素养分别为39.70%、46.59%,健康生活方式与行为素养分别为26.00%、37.39%,健康技能素养分别为27.30%、35.80%,科学健康观素养分别为46.80%、57.08%,传染病防治素养分别为21.85%、39.91%;慢性病防治素养分别为30.00%、39.38%,安全与急救素养分别为45.80%、64.82%,基本医疗素养分别为23.10%、29.96%,健康信息素养分别为45.80%、60.51%。2017年青岛市市北区健康素养水平的影响因素有文化程度、职业、家庭年收入,其中文化程度方面以大专/本科及以上O R值最高(O R=0.510,95%CI:0.357~0.728,P<0.01),职业方面以其他组O R值最高(O R=0.643,95%CI:0.440~0.940,P<0.05),家庭年收入方面1~2万元组差异有统计学意义(O R=0.086,95%CI:0.020~0.374,P<0.01)。2022年的影响因素仅有文化程度,大专/本科及以上组差异有统计学意义(O R=4.944,95%CI:1.071~22.826,P<0.05)。结论与2017年比较,2022年青岛市市北区居民健康素养提升较快;文化程度、职业、家庭年收入是居民健康素养水平的影响因素。

关键词：居民健康素养临界健康素养健康教育

肿瘤恶病质小鼠模型的建立及其相关分子机制研究进展

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国际呼吸杂志 2024年第5期44卷 598-604页

作者：高晨曦钟海林秋琪武良权杨健张允雷张秀伟南京医科大学附属江宁医院呼吸与危重症医学科南京211100

恶病质是肿瘤患者常见的临床并发症,表现为持续性体重下降、肌肉萎缩、乏力、贫血、营养不良等症状。建立肿瘤恶病质动物模型是探究其发病机制和寻找潜在治疗方法的重要策略之一。该类模型的建立有助于加深人们对恶病质发病机制的了解,... 详细信息

恶病质是肿瘤患者常见的临床并发症,表现为持续性体重下降、肌肉萎缩、乏力、贫血、营养不良等症状。建立肿瘤恶病质动物模型是探究其发病机制和寻找潜在治疗方法的重要策略之一。该类模型的建立有助于加深人们对恶病质发病机制的了解,以及肿瘤细胞与机体之间的相互作用,同时用于评估恶病质治疗药物的疗效和安全性。本文综述了肿瘤恶病质小鼠模型的建立及其相关分子机制的研究进展,并对肿瘤恶病质模型的构建和应用进行了讨论和展望。

关键词：肿瘤恶病质模型,动物发病机制

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矿柱稳定性影响因素敏感性分析及其应用研究

岩土力学 2014年第S1期35卷 271-277页

作者：宋卫东曹帅付建新江国建吴锋北京科技大学金属矿山高效开采与安全教育部重点实验室北京100083 北京科技大学土木与环境工程学院北京100083 招金矿业股份有限公司尹格庄金矿山东招远265414

为研究矿柱稳定性影响因素的敏感程度,以招金大尹格庄金矿为研究背景,从矿柱载荷、强度、失稳形式及影响因素确定四方面推导出两种矿柱形式的安全系数计算公式,设计采用6因素5水平正交试验对矿柱稳定性影响因素敏感性进行分析,并研究主... 详细信息

为研究矿柱稳定性影响因素的敏感程度,以招金大尹格庄金矿为研究背景,从矿柱载荷、强度、失稳形式及影响因素确定四方面推导出两种矿柱形式的安全系数计算公式,设计采用6因素5水平正交试验对矿柱稳定性影响因素敏感性进行分析,并研究主要影响因素与矿柱安全系数之间的函数关系。研究表明,矿柱宽度、矿体开采深度和矿房宽度3个主要因素对矿柱稳定性影响程度是最为剧烈的;矿柱安全系数随着矿柱宽度地增加呈指数形式递增且递增速率不断加大,随矿体开采深度地增加呈幂函数形式递减且递减速率逐渐变缓,随矿房宽度地增加呈负指数形式递减且降低速率逐渐变慢。利用DPS和Matlab建立的矿柱安全系数回归方程得出保证安全生产的合理矿柱尺寸,矿房宽度应不超过8 m,布置条形矿柱宽度应不小于3.6 m,布置方形矿柱宽度应不小于5.9 m。结合采场矿柱布置实际,应用效果较为理想,可为下中段矿体回采矿块布置提供较好的依据。

关键词：正交试验法敏感性分析矿柱稳定性安全系数法回归方程