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Percutaneous vertebroplasty in the treatment of malignant vertebral compression fractures with epidural involvement

Journal of Interventional Medicine 2018年第4期1卷 240-246页

作者： Yi-feng Gu Qing-Hua Tian Yong-Dong Li Chun-Gen wu Hong-Mei Song Cheng-jian He Department of Diagnostic and Interventional Radiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Purpose: To evaluate the safety and the clinical efficacy of percutaneous vertebroplasty(PVP) in treating malignant spinal tumors and malignant vertebral compression fractures with epidural involvement. Materials and methods: 43 patients with spinal metastatic tumors and malignant vertebral compression fractures with epidural involvement were treated using PVP. American Spinal Injury Association(ASIA) impairment scale results at presentation were used to divide patients into 2 groups. Patients in group A had no symptoms of neurological compression(n = 25); and patients in group B had symptoms of neurological compression(n = 28). A 13 G bone puncture needle was placed across the pedicle of the fractured vertebra, and polymethyl methacrylate(PMMA) was injected into the fractured vertebral body under fluoroscopic control. Patients were seen in follow-up at 1, 3, and 6 months after the procedure and every six months thereafter. Results: PVP was technically successful and well-tolerated in all patients. Clinical assessment at the final follow-up found complete pain relief(n = 19) or good pain relief(n = 14) in 33 patients(62.3%, 95% CI: 49%, 76%). ASIA impairment scale assessment at the final follow-up demonstrated symptoms of neurologic compression in 31 patients and no symptoms of neurologic compression in 22 patients. Symptoms of neurologic compression were found in five group A patients and eight group B patients. Conclusions: PVP was a safe and moderately effective procedure in the treatment of malignant vertebral compression fractures with epidural involvement.

关键词： percutaneous vertebroplasty pain malignant spinal tumor metastasis

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In situ studies of energy-related electrochemical reactions using Raman and X-ray absorption spectroscopy

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Chinese Journal of Catalysis 2022年第1期43卷 33-46页

作者： Heng‐Quan Chen Lie Zou Di‐Ye Wei Ling‐Ling Zheng Yuan‐Fei wu Hua Zhang jian‐feng Li College of Energy State Key Laboratory of Physical Chemistry of Solid SurfacesiChEMCollege of Chemistry and Chemical EngineeringCollege of MaterialsFujian Key Laboratory of Advanced MaterialsXiamen UniversityXiamen 361005FujianChina

Electrochemical energy conversion technologies involving processes such as water splitting and O_(2)/CO_(2) reduction,provide promising solutions for addressing global energy scarcity and minimizing adverse environmental ***,due to a lack of an in-depth understanding of the reaction mechanisms and the nature of the active sites,further advancement of these techniques has been limited by the development of efficient and robust ***,in situ characterization of these electrocatalytic processes under working conditions is *** this review,recent applications of in situ Raman spectroscopy and X-ray absorption spectroscopy for various nano-and single-atom catalysts in energy-related reactions are *** cases are highlighted,including the capture of oxygen-containing intermediate species formed during the reduction of oxygen and oxidation of hydrogen,and the detection of catalyst structural transformations occurring with the change in potential during the evolution of oxygen and reduction of CO_(2).Finally,the challenges and outlook for advancing in situ spectroscopic technologies to gain a deeper fundamental understanding of these energy-related electrocatalytic processes are discussed.

关键词： Raman spectroscopy X-ray absorption spectroscopy In situ characterization Electrocatalysis Energy conversion and storage

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The program structure designing and optimizing tests of GRAPES physics

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Chinese Science Bulletin 2008年第22期53卷 3470-3476页

作者： XU GuoQiang CHEN DeHui XUE JiShan SUN jian SHEN XueShun SHEN YuanFang HUANG LiPing wu XiangJun ZHANG HongLiang WANG ShiYu State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences Beijing 100081 China National Meteorological Centre Beijing 100081

According to the modularization and standardization of program structure in Global/Regional Assimilation and Prediction System (GRAPES), the plug-compatible and transplantable regional meso-scale and global middle-range physics software package is established. The package's component integrality is comparative with the other advanced models physics. A three-level structure of connecting GRAPES physics and dynamic frame has been constructed. The friendly interface is designed for users to plug in their own physics packages. Phenomenon of grid-point storm rainfall in numerical prediction is analyzed with the numerical tests. The scheme of air vertical velocity calculation is improved. Optimizing tests of physics schemes are performed with the correlative parameters adjusting. The results show that the false grid-point storm rainfall is removed by precipitation scheme improving. Then the score of precipitation forecast is enhanced.

关键词：数值天气预报天气预测气象分析暴雨

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基于支持向量机的柴油机排气阀智能故障诊断研究

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内燃机学报 2006年第5期24卷 465-469页

作者：武华锋李信伍建林苏毅后勤工程学院军事供油系

排气阀是柴油机的重要部件之一,其故障诊断一直受到研究者的关注,传统的学习机器在小样本学习时不具有良好的泛化能力,其现场效果与实验室精度差距较大。建立在统计学习理论基础之上的支持向量机具有和样本数相适应的最优泛化能力。利... 详细信息

排气阀是柴油机的重要部件之一,其故障诊断一直受到研究者的关注,传统的学习机器在小样本学习时不具有良好的泛化能力,其现场效果与实验室精度差距较大。建立在统计学习理论基础之上的支持向量机具有和样本数相适应的最优泛化能力。利用支持向量机适合处理高维数据以及具有良好泛化能力的特点,建立了排气阀故障诊断模型,将排气阀振动信号经过小波包分解后提取的特征指标在小样本时进行支持向量机学习,通过不同核函数的支持向量机和其它智能方法准确率的比较证明:支持向量机较其它智能方法有较大的优越性;准确率对核函数有一定的敏感性;在常用的3种核函数中,线性核的诊断准确率达到了100％,是柴油机排气阀智能故障诊断支持向量机的最佳核函数。

关键词：支持向量机排气阀故障诊断

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微生物组在乳腺肿瘤中的研究进展

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中国肿瘤外科杂志 2024年第1期16卷 89-92页

作者：张建苑书建周宏雷徐迪佘恬静吴怡吴雅茹王丹丹侯俊宸吴旸唐金海孙明明南京医科大学第一附属医院普外科江苏南京210029 南京农业大学土壤生态学实验室江苏南京210095

乳腺癌是女性最常见的恶性肿瘤,探索其发生发展的机制和治疗策略是目前研究的难点。该文重点综述了微生物群在乳腺癌发展及治疗中的研究进展。研究显示,乳腺肿瘤内微生物群对于促进肿瘤转移有着不可忽视的作用;同时,肠道微生物的变化不... 详细信息

乳腺癌是女性最常见的恶性肿瘤,探索其发生发展的机制和治疗策略是目前研究的难点。该文重点综述了微生物群在乳腺癌发展及治疗中的研究进展。研究显示,乳腺肿瘤内微生物群对于促进肿瘤转移有着不可忽视的作用;同时,肠道微生物的变化不仅与乳腺癌的发生密切相关,也对治疗效果有显著影响,尤其体现在药物作用机制及免疫治疗的响应性方面。此外,噬菌体展示技术通过筛选出肿瘤特异性蛋白质,为靶向治疗提供了新途径。微生物群和噬菌体作为潜在的诊断工具,已经在癌症风险评估方面展现出新的研究潜力。未来应深入研究微生物群对乳腺癌的调控机制及乳腺癌与肠道微生物的交互作用,以期为乳腺癌的进一步诊断和治疗提供更多新思路。

关键词：乳腺癌微生物群噬菌体研究进展

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Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels

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Journal of Animal Science and Biotechnology 2019年第1期10卷 172-182页

作者： Heju Zhong Peng Wang Yumo Song Xiaoling Zhang Lianqiang Che Bin feng Yan Lin Shengyu Xu jian Li De wu Qiaofeng wu Zhengfeng Fang Key Laboratory for Animal Disease Resistance Nutrition of the Ministry of Education Animal Nutrition InstituteSichuan Agricultural University Acupuncture and Moxibustion College Chengdu University of Traditional Chinese Medicine

Background: Persistent lactation,as the result of mammary cellular anabolism and secreting function,is dependent on substantial mobilization or catabolism of body reserves under nutritional ***,little is known about the biochemical mechanisms for nutrition-restricted lactating animals to simultaneously maintain the anabolism of mammary cells while catabolism of body *** present study,lactating sows with restricted feed allowance(RFA)(n = 6),24% feed restriction compared with the control(CON) group(n = 6),were used as the nutrition-restricted *** and mammary venous cannulas methods were used to monitor postprandial dynamic changes of metabolites in adipose and mammary ***: At lactation d 28,the RFA group showed higher(P 0.05) between ***,piglet performance and milk yield did not differ(P > 0.05) between *** would appear that activation of Notch signaling and adequate supply of glutamate might assist ***: Mammary cell proliferation and catabolism of adipose tissues i

关键词： Glutamate Insulin sensitivity Lipolysis Mammary cell proliferation

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Successful treatment of a pancreatic schwannoma by spleen-preserving distal pancreatectomy

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World Journal of Gastroenterology 2017年第20期23卷 3744-3751页

作者： Shao-Yan Xu Ying-Sheng wu jian-Hui Li Ke Sun Zhen-Hua Hu Shu-Sen Zheng Wei-Lin Wang Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryFirst Affiliated HospitalSchool of MedicineZhejiang University Key Laboratory of Combined Multi-organ Transplantation Ministry of Public HealthFirst Affiliated HospitalSchool of MedicineZhejiang University Key Laboratory of Organ Transplantation Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Zhejiang University Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province Department of Pathology First Affiliated HospitalSchool of MedicineZhejiang University

Schwannomas are neurogenic tumors that arise from the neural sheaths of peripheral nerves. These tumors can be located in any area of the human body; the most common locations are the head, neck, trunk and extremities. Pancreatic schwannomas are very rare. Over the past 40 years, only 67 cases of pancreatic schwannomas have been reported in the English literature. Here we present a case of pancreatic schwannoma in a 62-year-old male. The tumor was revealed by ultrasound and computed tomography in the neck and body of the pancreas. An accurate diagnosis was difficult to obtain preoperatively. The patient consented to the performance of a laparotomy, and the mass was found in the neck and body of the pancreas and successfully treated using a spleen-preserving distal pancreatectomy with splenic artery and vein preservation. The procedure has only been reported in one other case of pancreatic schwannoma; here we present the second reported case. Macroscopically, the tumor was well circumscribed, gray-white in color and 3.3 cm x 2.8 cm in size. Microscopically, the tumor cells were spindle-shaped and had a palisading arrangement with no atypia, which are results compatible with a benign tumor. Both hypercellular and hypocellular areas were visible. Immunohistochemically, the tumor cells were strongly positive for S-100 protein. The tumor was definitively diagnosed as a schwannoma of the pancreatic neck and body. The patient was followed for 72 mo and has been doing well without any complications.

关键词： Schwannoma Pancreas Spleen-preserving distal pancreatectomy S-100 Mesenchymal tumor

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A study on deep structure using teleseismic receiver function in Western Yunnan

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Acta Seismologica Sinica(English Edition) 2004年第3期17卷 262-271页

作者： HE Chuan-song(贺传松) WANG Chun-yong(王椿镛) wu jian-ping(吴建平) Institute of Geophysics China Earthquake AdministrationBeijing 100081China Institute of GeophysicsChina Earthquake AdministrationBeijing 100081China Institute of GeophysicsChina Earthquake AdministrationBeijing 100081China

s Western Yunnan is located at the boundary of collision or underthrusting zone of Eurasian plate and is influenced by many times tectonic movements. With very complex geological environment and tectonic background, it is one of the seismically active areas. In the paper, the teleseismic records were selected from 16 national, local and mo-bile stations, including 4 very-wide-band mobile stations of PASSCAL. And nearly 2 000 receiver functions were extracted. Two measuring lines are 650 km and 450 km, respectively and across some major tectonic units in Western Yunnan. It is indicated that Nujiang might be a seam characterized by underthrusting. The western and eastern boundaries of Sichuan-Yunnan rhombus block, i.e., Honghe and Xiaojiang faults, might be an erection seam or collision belt. Panxi tectonic zone still has the characteristics of continental rift valley, that is, the surface is hollow and the upper mantle is upwarping. The tectonic situation in Western Yunnan is of certain regulation with the interlacing distribution of orogenic zone and seam. The crustal thickness decreases gradually from the north to the south and the S wave velocity is globally lower here.

关键词： receiver function inversion S wave velocity structure tectonic relationship

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Identification of Novel Stress-responsive Transcription Factor Genes in Rice by cDNA Array Analysis

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Journal of Integrative Plant Biology 2006年第10期48卷 1216-1224页

作者： Cong-Qing wu Hong-Hong Hu Ya Zeng Da-Cheng Liang Ka-Bin Xie jian-Wei Zhang Zhao-Hui Chu Li-Zhong Xiong National Key Laboratory of Crop Genetic Improvement National Plant Gene Research Center Huazhong Agricultural University Wuhan 430070 China

Numerous studies have shown that array of transcription factors has a role in regulating plant responses to environmental stresses. Only a small portion of them however, have been Identified or characterized. More than 2 300 putative transcription factors were predicted In the rice genome and more than half of them were supported by expressed sequences. With an attempt to Identify novel transcription factors involved in the stress responses, a cDNA array containing 753 putative rice transcription factors was generated to analyze the transcript profiles of these genes under drought and salinity stresses and absclsic acid treatment at seedling stage of rice. About 80% of these transcription factors showed detectable levels of transcript in seedling leaves. A total of 18 up-regulated transcription factors and 29 down-regulated transcription factors were detected with the folds of changes from 2.0 to 20.5 in at least one stress treatment. Most of these stress-responsive genes have not been reported and the expression patterns for five genes under stress conditions were further analyzed by RNA gel blot analysis. These novel stress-responsive transcription factors provide new opportunities to study the regulation of gene expression In plants under stress conditions.

关键词： abiotic stress cDNA array Oryza sativa transcription factor

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Effects of Propofol on Respiratory Drive and Patient-ventilator Synchrony during Pressure Support Ventilation in Postoperative Patients： A Prospective Study

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Chinese Medical Journal 2017年第10期130卷 1155-1160页

作者： Ling Liu Ai-Ping wu Yi Yang Song-Qiao Liu Ying-Zi Huang jian-feng Xie Chun Pan Cong-Shan Yang Hai-Bo Qiu Department of Critical Care Medicine School of Medicine Nanjing Zhongda Hospital Southeast University Nanjing Jiangsu 210009 China

Background： Propofol is increasingly nsed during partial support mechanical ventilation such as pressure support ventilation （PSV） in postoperative patients. However breathing pattern, respiratory drive, and patient-ventilator synchrony are affected by the sedative used and the sedation depth. The present study aimed to evaluate the physiologic effects of varying depths ofpropofbl sedation oll respiratory drive and patient-ventilator synchrony during PSV in postoperative patients. Methods： Eight postoperative patients receiving PSV for 〈24 h were enrolled. Propofol was administered to achieve and maintain a Ramsay score of 4, and the inspiratory pressure support was titrated to obtain a tidal volume （VT） of 6-8 ml/kg. Then, tile propolbl dose was reduced to achieve and maintain a Ramsay score of 3 and then 2. At each Ramsay level, the patient underwent 30-rain trials of PSV. We measured the electrical activity of the diaphragm, flow, airway presstlre, neuro-ventilatory efficiency （NVE）, and patient-ventilator synchrony. Results： Increasing the depth of sedation reduced the peak and mean electrical activity of the diaphragm, which suggested a decrease in respiratory drive, while VT remained unchanged. The NVE increased with an increase in the depth of sedation. Minute ventilation and inspiratory duty cycle decreased with an increase in the depth of sedation, but this only achieved statistical significance between Ramsay 2 and both Ramsay 4 and 3 （P 〈 0.05）. The ineffective triggering index increased with increasing sedation depth （9.5 -4- 4.0%, 6.7 - 2.0%, and 4.2-2.1% for Ramsay 4, 3, and 2, respectively） and achieved statistical significance between each pair of depth of sedation （P 〈 0.05）. The depth of sedation did not affect gas exchange. Conclusions： Propofol inhibits respiratory drive and deteriorates patient-ventilator synchrony to tile extent that varies with tile depth of sedation. Propolbl has less effect on breathing pattern and has no effect on VT and ga

关键词： Electrical Activity of Diaphragm Patient-ventilator Synchrony Propofol Respiratory Drive

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