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Mechanical Properties of Lime-Fly Ash-Sulphate Aluminum Cement Stabilized Loess

Journal of Renewable Materials 2020年第10期8卷 1357-1373页

作者： liang jia Chunxiang Li jian Guo College of Civil Engineering Lanzhou University of TechnologyLanzhou730050China

Lime-fly ash stabilized loess has a poor early strength,which results in a later traffic opening time when it is used as road-base *** of the significant early strength characteristics of sulphate aluminum cement(SAC),it is always added into the lime-fly ash mixtures to improve the early strength of stabilized ***,there is a scarcity of research on the mechanical behavior of lime-fly ash-SAC stabilized loess and there is a lack of quantitative evaluation of loess stabilized with binder *** research explored the effects of the amount of binder materials,curing time and porosity on the unconfined compressive strength(UCS),splitting tensile strength(STS),cohesion(c)and friction angle(φ)of lime-fly ash-SAC stabilized loess by a series of unconfined compressive tests(UCT)and splitting tensile tests(STT).The results indicate that an increase in curing time and a decrease in porosity lead to a continuous increase in the UCS and STS for lime-fly ash-SAC stabilized *** addition of SAC has a prominent enhancement in the early strength of lime-fly ash-SAC stabilized *** the curing time,porosity,and binder content were constant,the UCS and STS increase with increasing SAC content;For a stabilized loess with 30%binder content and 5%SAC content after 1 day of curing,the UCS was greater than 0.7 MPa,which meets the requirement of opening traffic,so lime-fly ash-SAC stabilized loess could be used as an excellent maintenance material for road-base;In accordance with the analysis of testing data,empirical relationships between the UCS and STS of lime-fly-SAC stabilized loess and key effect factors(binder materials content,curing time and porosity)were developed,which can provide references for reasonably selecting the amount of binder materials,compaction degree and curing period to meet the required strength of practical ***,based on the Mohr-Coulomb theory and the above empirical relationships,a simpler method f

关键词： Loess sulphate aluminum cement unconfined compressive strength splitting tensile strength

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车用高功率密度电机扩速拓矩研究

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重庆理工大学学报(自然科学) 2025年第1期39卷 140-147页

作者：梁栋陶健陈星重庆交通大学机电与车辆工程学院重庆400074 重庆文理学院智能制造工程学院重庆402160

基于车用电机扩速拓矩的性能需求设计了一种采用永磁体分段结构的优化反凸极永磁同步电机。介绍了反凸极电机的结构和设计原则;以扩宽恒功率转速范围和提升电磁拓矩为目标,以凸极率为约束,利用粒子群算法(PSO)对电机进行多目标优化,并... 详细信息

基于车用电机扩速拓矩的性能需求设计了一种采用永磁体分段结构的优化反凸极永磁同步电机。介绍了反凸极电机的结构和设计原则;以扩宽恒功率转速范围和提升电磁拓矩为目标,以凸极率为约束,利用粒子群算法(PSO)对电机进行多目标优化,并对比分析优化前后电机的性能。有限元仿真分析结果表明:结构优化后,相比于优化前转矩提升了16%,转速范围由5:1提升到6.5:1,验证了优化电机提升转矩和扩宽转速范围的有效性。

关键词：永磁同步电机反凸极多目标优化恒功率转速范围

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底部斜升角和浮心位置对高速滑行艇水动力的影响分析

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船海工程 2025年第1期54卷 60-65,70页

作者：梁家健程红蓉陈京普中国船舶科学研究中心江苏无锡214082 深海技术科学太湖实验室连云港中心江苏连云港222000

基于CFD技术,利用DFBI运动模型,结合重叠网格技术,在保证排水体积相同的前提下,对某滑行艇开展底部斜升角、浮心位置对水动力性能的影响研究。根据阻力、升沉、纵倾及自由液面兴波云图等选取较优的底部斜升角及浮心位置方案,开展模型试... 详细信息

基于CFD技术,利用DFBI运动模型,结合重叠网格技术,在保证排水体积相同的前提下,对某滑行艇开展底部斜升角、浮心位置对水动力性能的影响研究。根据阻力、升沉、纵倾及自由液面兴波云图等选取较优的底部斜升角及浮心位置方案,开展模型试验研究。对比最终线型在不同航速下、模型试验与数值计算的结果表明,利用CFD方法能够准确预估滑行艇的阻力与运动状态,为滑行艇底部斜升角及浮心纵向位置等参数选取及艇型设计提供借鉴。

关键词：滑行艇 DFBI运动重叠网格参数设计模型试验

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Oxidative stress-induced circSOD2 inhibits osteogenesis through sponging miR-29b in metabolic-associated fatty liver disease

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World Journal of Gastroenterology 2025年第9期31卷 68-82页

作者： liang-Ping Li Xiao-Ying Chen Hong-Bo Liu Yi Zhu Min-Jie Xie Yong-jian Li Meng Luo Mugahed Albahde Hong-Yu Zhang jian-Ying Lou Department of Hepatobiliary and Pancreatic Surgery The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Emergency Medicine The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of General Surgery The People’s Hospital of SongyangLishui 323400Zhejiang ProvinceChina

BACKGROUND Metabolic-associated fatty liver disease(MAFLD)is characterized by lipid accumulation in hepatocytes and is closely associated with oxidative *** clinical evidence indicates that MAFLD is linked to bone metabolic disorders,including *** studies indicate that the expression profiles of liver circular RNAs(circRNAs)are altered in ***,the effects of these changes on bone metabolism remain poorly *** To investigate the effects and mechanism of differently expressed circRNAs secreted by the liver on osteogenic differentiation in *** RNA sequencing was performed to identify highly expressed circRNAs in the liver,validated by quantitative real-time reverse transcription polymerase chain reaction,and localized using fluorescence in situ hybridization(FISH).A mouse model induced by a high-fat diet was used to simulate *** CircSOD2 was significantly upregulated in liver tissues and primary hepatocytes from subjects with ***2 was induced by oxidative stress and attenuated by antioxidants in the mouse *** addition,circSOD2 was delivered from hepatocytes to bone marrow mesenchymal stem cells(BMSCs).Furthermore,circSOD2 inhibited the osteogenic differentiation of BMSCs and in vivo bone formation by sponging ***,miR-29b inhibition reversed the stimulatory effect of circSOD2 silencing on osteogenic differentiation of BMSCs and in vivo bone ***,the interaction between circSOD2 and miR-29b confirmed through a luciferase reporter assay and the co-localization in the cytoplasm evidenced by FISH indicated that circSOD2 acted as a sponge for *** This study provides a novel mechanism underlying the liver-bone crosstalk,demonstrating that circSOD2 upregulation in hepatocytes,induced by oxidative stress,inhibits osteogenic differentiation of BMSCs by sponging *** findings offer a better understanding of the relationship between MAFLD an

关键词： Circular RNAs MicroRNAs Oxidative stress Osteogenesis Non-alcoholic fatty liver disease Osteoporosis

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声波曲线分层重构反演在岩性预测中的应用

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大庆石油地质与开发 2010年第4期29卷 167-170页

作者：林东成张宏贾建亮李润琪刘招君方石大庆油田有限责任公司勘探开发研究院黑龙江大庆163712 吉林大学地球科学学院吉林长春130061 北京大学北京100871

塔南凹陷属于断、坳叠置盆地，不适合对全井段或大范围数据进行声波曲线重构。为了提高塔南凹陷岩性预测精度，分析了地层岩石物理性质及测井响应、地震响应特征；从反映岩性能力较强的伽马、声波曲线中分别获取高、低频信息，在对其进... 详细信息

塔南凹陷属于断、坳叠置盆地，不适合对全井段或大范围数据进行声波曲线重构。为了提高塔南凹陷岩性预测精度，分析了地层岩石物理性质及测井响应、地震响应特征；从反映岩性能力较强的伽马、声波曲线中分别获取高、低频信息，在对其进行融合的基础上获得了拟声波曲线并用于井约束反演。应用结果表明，拟声波曲线提高了岩性分辨能力，声波曲线分层重构反演技术能够提高反演的分辨率和精度，反演成果符合率从78％提高到86％。

关键词：塔南凹陷声波曲线分层重构井约束反演岩性预测

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Analysis of PM2.5 and O3 Pollution Causes in Hangzhou Based on High-resolution Enhanced Observation During the Asian Games

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Huanjing Kexue/Environmental Science 2025年第3期46卷 1302-1313页

作者： Yan, Ren-Chang Lai, Yong Zhang, Tian Jin, jia-jia Lin, Xu Wang, Yun-Yun Shuai, Qi-Fan Fei, Luo-Lan Shen, jian-Dong Ye, Xuhong Zhu, Shu-Hui Hangzhou Ecological Environment Monitoring Center of Zhejiang Hangzhou310007 China Shanghai Academy of Environmental Sciences Shanghai200003 China

Based on the high-resolution enhanced observation data of PM2.5 organic molecular tracers,aldehydes and ketone OVOC components,long-chain alkane IVOC components,and key species of atmospheric oxidation during September 1 to October 27,2023,the causes of PM2.5 and O3 pollution in Hangzhou were analyzed. Seven pollution processes were selected with the average daily concentration of PM2.5 exceeding 35 µg·m-3 or the maximum 8-hour concentration of O3 exceeding 160 µg·m-3. Then,these pollution processes were divided into four types:north-northeast transmission type(T1),east-southeast transmission type(T2),north-northwest transmission type(T3),and statically stable type(T4)by airflow trajectory. The research results indicated that the T2 pollution process exhibited strong PM2.5 and O3 composite pollution characteristics and the photochemical oxidation reaction of active VOC components,such as long-chain alkanes and terpenes in the atmospheric environment was the major pollution cause of this type. In the process of T1 and T3 pollution,the overall reactivity of VOCs was low,resulting in relatively weak O3 generation. However,the causes of PM2.5 in these two types of pollution processes were different. T1 pollution was affected by low temperature and high humidity meteorological conditions and the enhanced liquid-phase oxidation process led to a significant increase in nitrate concentration. T3 pollution was significantly affected by emissions from coal combustion,biomass combustion,and other sources,with a relatively high proportion of primary components in PM2.5. The T4 pollution process was significantly affected by local primary anthropogenic emissions,thus the control of local catering source and mobile source emissions must be strengthened. © 2025 Science Press. All rights reserved.

关键词： Coal combustion

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Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer‑like social memory loss

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Military Medical Research 2025年第1期12卷 48-71页

作者： Hui-Yang Lei Gui-Lin Pi Ting He Rui Xiong Jing-Ru Lv jia-Le Liu Dong-Qin Wu Meng-Zhu Li Kun Shi Shi-Hong Li Na-Na Yu Yang Gao Hui-Ling Yu Lin-Yu Wei Xin Wang Qiu-Zhi Zhou Pei-Lin Zou jia-Yang Zhou Ying-Zhou Liu Nai-Ting Shen Jie Yang Dan Ke Qun Wang Gong-Ping Liu Xi-Fei Yang jian-Zhi Wang Ying Yang Department of Pathophysiology School of Basic MedicineKey Laboratory of Education Ministry of China/Hubei Province for Neurological DisordersTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Traditional Chinese Medicine the Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430014China Key Laboratory of Modern Toxicology of Shenzhen Shenzhen Center for Disease Control and PreventionShenzhen 518055GuangdongChina Co‑Innovation Center of Neuroregeneration Nantong UniversityNantong 226000JiangsuChina

Background:Episodic memory loss is a prominent clinical manifestation of Alzheimer’s disease(AD),which is closely related to tau pathology and hippocampal *** to the heterogeneity of brain neurons,the specific roles of different brain neurons in terms of their sensitivity to tau accumulation and their contribution to AD-like social memory loss remain ***,further investigation is ***:We investigated the effects of AD-like tau pathology by Tandem mass tag proteomic and phosphoproteomic analysis,social behavioural tests,hippocampal electrophysiology,immunofluorescence staining and in vivo optical fibre recording of GCaMP6f and ***,we utilized optogenetics and administered ursolic acid(UA)via oral gavage to examine the effects of these agents on social memory in ***:The results of proteomic and phosphoproteomic analyses revealed the characteristics of ventral hippocampal CA1(vCA1)under both physiological conditions and AD-like tau *** tau progressively accumulated,vCA1,especially its excitatory and parvalbumin(PV)neurons,were fully filled with mislocated and phosphorylated tau(p-Tau).This finding was not observed for dorsal hippocampal CA1(dCA1).The overexpression of human tau(hTau)in excitatory and PV neurons mimicked AD-like tau accumulation,significantly inhibited neuronal excitability and suppressed distinct discrimination-associated firings of these neurons within *** excitatory and PV neurons in vCA1 at specific rhythms and time windows efficiently ameliorated tau-impaired social ***,1 month of UA administration efficiently decreased tau accumulation via autophagy in a transcription factor EB(TFEB)-dependent manner and restored the vCA1 microcircuit to ameliorate tau-impaired social ***:This study elucidated distinct protein and phosphoprotein networks between dCA1 and vCA1 and highlighted the susceptibility of the vCA1 microcircuit to AD-like tau

关键词： Alzheimer’s disease Tau protein Ventral hippocampus Social memory Ursolic acid Transcription factor EB(TFEB)

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数字技术创新赋能开源社区知识产权治理的生发逻辑、体系构建与实践路径

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科学管理研究 2025年第1期43卷 59-68页

作者：胡剑贾怡炜戚湧南京理工大学知识产权学院江苏南京210094 南京理工大学经济管理学院江苏南京210094

伴随大数据、区块链和人工智能等新一代数字技术的加速创新,数字技术成为开源社区知识产权治理的有效工具,对推动开源生态高质量发展具有重要意义。立足中国式现代化背景,分析数字创新和开放式创新发展下开源社区存在的知识产权问题和... 详细信息

伴随大数据、区块链和人工智能等新一代数字技术的加速创新,数字技术成为开源社区知识产权治理的有效工具,对推动开源生态高质量发展具有重要意义。立足中国式现代化背景,分析数字创新和开放式创新发展下开源社区存在的知识产权问题和治理需求,探究在数字技术创新外部契机下开源社区知识产权治理的生发逻辑。基于系统论和活动理论三角形模型,建构数字技术创新赋能开源社区知识产权治理体系框架,明确治理目标、治理客体、治理主体和治理方式。结合危机三阶段理论提出数字技术创新赋能开源社区知识产权事前、事中和事后治理运行流程。结合活动理论下的体系要素互动特征和子系统,提出发挥制度优势夯实基础、革新数字技术提升动能和协同共治凝聚主体的不同实践路径。研究旨为开源创新体系建设和知识产权治理现代化提供理论参考和实践借鉴。

关键词：开源社区知识产权治理数字技术创新治理体系活动理论

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Short-term efficacy of early percutaneous cholecystostomy for pancreatitis and factors associated with recurrence and mortality

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World Journal of Gastroenterology 2025年第6期31卷 20-33页

作者： Xin Yan Feng Xie Xiao-Dan Zhao liang Li jia-Xian Meng Department of Nuclear Medicine The People’s Hospital of Liaoning ProvinceShenyang 110016Liaoning ProvinceChina Department of Interventional Medicine Jin Qiu Hospital of Liaoning ProvinceShenyang 110016Liaoning ProvinceChina Department of General Surgery The People’s Hospital of Liaoning ProvinceShenyang 110016Liaoning ProvinceChina Department of Science and Education The People’s Hospital of Liaoning ProvinceShenyang 110016Liaoning ProvinceChina

BACKGROUND Percutaneous cholecystostomy(PC)can be used as a bridging therapy for moderately severe acute biliary pancreatitis(MSABP).Currently,there are only a limited number of reports of MSABP using *** To assess the short-term outcomes of early PC in MSABP and factors associated with recurrence and death in *** Patients who received conservative treatment or PC for acute biliary pancreatitis(ABP)in Liaoning Provincial People’s Hospital from January 2017 to July 2022 were collected.A total of 54 patients with MSABP who received early-stage PC and 29 patients who received conservative *** short-term efficacy of PC was *** on whether there is a recurrence,compare the characteristics of the pre-PC and explore the factors of ***-PC features were compared and predictors were discussed,depending on the *** After 3 days of PC treatment,patients experienced a reduction in inflammatory markers compared to the conservative *** PC,patients were divided into non-recurrence(n=37)and recurrence(n=10)groups,and the results showed that age was an independent correlation affecting ABP recurrence[odds ratio(OR)=0.937,95%confidence interval(CI):0.878-0.999;P=0.0470.7).When the Youden index maximum was 0.565,the cut-off value was 5.5,the sensitivity was 71.4%,and the specificity was 85.1%.CONCLUSION PC is an important method in the early years(<72 hours)of *** is a protective factor against recurrence of *** pre-PC CCI is significantly associated with mortality.

关键词： Acute biliary pancreatitis Percutaneous cholecystostomy The revised Atlanta classification Charleson Comorbidity Index Yoden index

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Correction:A novel method for simultaneous measurement of ^(222)Rn and ^(220)Rn progeny concentrations measured by an alpha spectrometer

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Nuclear Science and Techniques 2025年第2期36卷 157-157页

作者： Zhong-Kai Fan jia-Le Sun Hao-Xuan Li Xiang-Ming Cai Hui Yang Shou-Kang Qiu Yan-liang Tan jian Shan School of Nuclear Science and Technology University of South ChinaHengyang 421001China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421008China

Correction to:Nuclear Science and Techniques(2024)36:8 https://***/10.1007/s41365-024-01570-7 In this article the affiliation details for Author jian Shan were incorrectly given as‘College of Physics and Electronic Engi-neering,Hengyang Normal University,Hengyang 421008,China’but should have been‘School of Nuclear Science and Technology,University of South China,Hengyang 421001,China’.The original article has been corrected.

关键词： details simultaneous corrected

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