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Gastrointestinal Microbiome and related metabolites in Depression and Antidepressants - a comprehensive review

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Life Research 2023年第3期6卷 47-58页

作者： Yan-Li Lu Tao jiang jia-jia duan College of Basic Medicine and Forensic Medicine Henan University of Science and TechnologyLuoyang 471003China Department of Clinical Laboratory The First Affiliated Hospitaland College of Clinical Medicine of Henan University of Science and TechnologyLuoyang 471003China

Depression,a prevalent mood disorder,has emerged as a significant health concern in *** the exact cause of depression remains incompletely understood,there is substantial evidence linking the gastrointestinal microbiome and its metabolites to this *** combined multi-omics analysis,it has been observed that the composition of the gastrointestinal microbiome,including Firmicutes,Bacteroidetes,and Actinobacteria,undergoes significant alterations in depressed ***,the production of short-chain fatty acids,tryptophan,and bile acids by these gut microbes is also found to be modified in ***,studies have demonstrated that antidepressant medications exert their therapeutic effects by interacting with the gastrointestinal microbiome and their *** review provides an overview of the association between the gastrointestinal microbiome,related metabolites,and *** highlights the potential of these factors to serve as mechanisms of action for antidepressant ***,the review summarizes the commonly used technical tools in depression research.

关键词： Gastrointestinal microbiome Metabolomics Antidepressants Depressive disorder Traditional Chinese medicine

ViTAU:基于Vision transformer和面部动作单元的面瘫识别与分析

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工程科学学报 2025年第2期47卷 351-363页

作者：高嘉蔡文浩赵俊莉段福庆青岛大学计算机科学技术学院青岛266071 北京师范大学人工智能学院北京100875

面部神经麻痹(Facial nerve paralysis,FNP),通常称为贝尔氏麻痹或面瘫,对患者的日常生活和心理健康产生显著影响,面瘫的及时识别和诊断对于患者的早期治疗和康复至关重要.随着深度学习和计算机视觉技术的快速发展,面瘫的自动识别变得可... 详细信息

面部神经麻痹(Facial nerve paralysis,FNP),通常称为贝尔氏麻痹或面瘫,对患者的日常生活和心理健康产生显著影响,面瘫的及时识别和诊断对于患者的早期治疗和康复至关重要.随着深度学习和计算机视觉技术的快速发展,面瘫的自动识别变得可行,为诊断提供了一种更准确和客观的方式.目前的研究主要集中关注面部的整体变化,而忽略了面部细节的重要性.面部不同部位对识别结果的影响力并不相同,这些研究尚未对面部各个区域进行细致区分和分析.本项研究引入结合Vision transformer(ViT)模型和动作单元(Action unit,AU)区域检测网络的创新性方法用于面瘫的自动识别及区域分析.ViT模型通过自注意力机制精准识别是否面瘫,同时,基于AU的策略从StyleGAN2模型提取的特征图中,利用金字塔卷积神经网络分析受影响区域.这一综合方法在YouTube Facial Palsy(YFP)和经过扩展的Cohn Kanade(CK+)数据集上的实验中分别达到99.4%的面瘫识别准确率和81.36%的面瘫区域识别准确率.通过与最新方法的对比,实验结果展示了所提的自动面瘫识别方法的有效性.

关键词： Transformer 面部动作单元多分辨率特征图生成器热力图回归

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Two-dimensional ballistic transistors for advanced-node integrated circuits

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National Science Review 2024年第3期11卷 9-10页

作者： jia Li Xidong duan Hunan Provincial Key Laboratory of Two-Dimensional Materials State Key Laboratory for Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University

As the feature size of metal-oxide-semiconductor-field-effect-transistors(MOSFETs) in integrated circuits(ICs)is reduced to sub-10-nm, the traditional channel materials are plagued by enhanced scattering and short-channel effects, leading to the deterioration of switching characteristics and the increase of power consumption.

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Electron and configuration engineering of atomic Cu and multioxidated Cu_(2+1)O centers via gasifiable reductant strategy for efficient oxygen reduction toward Zn-air battery

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Nano Research 2023年第2期16卷 2383-2391页

作者： Hongbin Li jia-jia Zheng Mingfan Yang Jingui duan State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Laboratory of Theoretical and Computational Nanoscience National Center for Nanoscience and TechnologyChinese Academy of SciencesBeijing 100190China

Efforts in a large number of transition metal-carbon systems are devoted to the development of efficient catalysts for oxygen reduction reaction(ORR).However,unsatisfied O_(2)adsorption and slow reduction of OH*at the active centers hinder the further development of these *** here report a gasifiable reductant strategy,of which a new Cu-based metal organic framework(MOF:termed NTU-83)nanosheet was co-pyrolyzed with melamine to produce the N-coordinated atomic Cu and multi-oxidated Cu_(2+1)O active centers on the carbon foam with ultrathin *** engineered electrons and configuration of the active centers boost the catalyst(Cu/NC-1000)to show superior ORR activity(E_(1/2)=0.85 V),excellent stability,and methanol *** modeling calculation and controlled experiments reveal that the Cu_(2+1)O species play a crucial role in kinetically accelerated adsorption and activation of O_(2),while the N_(4)coordinated atomic Cu facilitates fast reduction of OH*.Such characteristics endow the Zn-air battery that containing Cu/NC-1000 as air cathode to show a high peak power density(138 mW·cm^(−2)),a high specific capacity of 763 mAh·gZn^(−1),and outstanding long-term cycle *** plausible mechanism and excellent performance show that gasifiable reductant strategy opens up a new route for regulation of the electronic of active sites but also provides a candidate for the practical application in energy conversion/storage devices.

关键词： metal organic framework nanosheet carbon foam atomic Cu Cu_(2+1)O nanosheet electron and configuration engineering

Efficient adsorption to hexavalent chromium by iron oxalate modified D301:Characterization,performance and mechanisms

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Chinese Journal of Chemical Engineering 2021年第5期34卷 61-69页

作者： Dongmei jia Huamin Cai Yongzheng duan jiangbao Xia jia Guo School of Chemical Engineering and Safety Binzhou UniversityBinzhou 256603China School of Chemical Engineering and Pharmaceutical Wuhan Institute of TechnologyWuhan 430073China Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta Binzhou UniversityBinzhou 256603China

Chromium is a common harmful pollutant with high toxicity and low bearing capacity of soil and *** salinity resistance,a wide pH range,and high regeneration capacity were essential for qualified adsorbents used in removing hexavalent chromium(Cr(VI))from polluted ***,iron oxalate modified weak basic resin(IO@D301)for the removal of Cr(VI)was prepared by the impregnation *** IO@D301 was characterized by scanning electron microscope(SEM),Fourier transform infrared spectroscopy(FTIR),X-Ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS).Owing to abundant amine,carboxyl groups and iron ions existing on the surface,IO@D301 possesses high adsorption and salinity resistance capacity for Cr(VI).The maximum adsorption capacity of IO301 towards Cr(VI)reached 201.30 mg·g^(-1) at 293 K and a pH of *** adsorption equilibrium was well fitted by the Freundlich model,and the adsorption process was described by the pseudofirst-order kinetics model as spontaneous and *** mechanism may be identified as electrostatic attraction,coordination,and reduction,which was confirmed by FT-IR and X-ray photoelectron spectroscopy.

关键词： D301 Iron oxalate Chromium Adsorption

Fixed-Time Cluster Optimization for Multi-Agent Systems Based on Piecewise Power-Law Design

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1301-1303页

作者： Suna duan Xinchun jia Xiaobo Chi School of Mathematical Sciences Shanxi UniversityTaiyuan 030006China School of Automation and Software Engineering Shanxi UniversityTaiyuan 030013China

Dear Editor,This letter focuses on the fixed-time(FXT)cluster optimization problem of first-order multi-agent systems(FOMASs)in an undirected network,in which the optimization objective is the sum of the objective functions of all clusters.A novel piecewise power-law control protocol with cooperative-competition relations is ***,a sufficient condition is obtained to ensure that the FOMASs achieve the cluster consensus within an FXT.

关键词： agent cluster optimization

Nanostructured lubricant additives for titanium alloy:Lubrication by the solid-liquid interface with Coulomb repulsion

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Friction 2024年第7期12卷 1564-1579页

作者： Linlin duan Dan jia jian LI jianfang LIU Haitao duan State Key Laboratory of Special Surface Protection Materials and Application Technology Wuhan Research Institute of Materials ProtectionWuhan 430030China Hubei Longzhong Laboratory Xiangyang 441000China College of Life Science and Technology Wuhan Polytechnic UniversityWuhan 430030China

In this work,the advantage of Coulomb repulsion in the intermolecular forces experienced by molecules on the solid–liquid nanosized contact interface is taken,and the superior friction-reducing property of Cu_(3)(PO_(4))2·3H_(2)O(CuP)oil-based additives has been confirmed for titanium ***-dimensional(3D)CuP nanoflowers(CuP-Fs)with a strong capillary absorption effect are prepared to achieve the homogeneous mixing of solid CuP and lubricating *** by CuP-Fs additives for titanium alloy,friction coefficient(COF)can be reduced by 73.68%,and wear rate(WR)reduced by 99.69%.It is demonstrated that the extraordinary friction-reducing property is due to the repulsive solid–liquid interface with low viscous shear force originating from Coulomb repulsion between polar water molecules in CuP and non-polar oil ***,any steric hindrance or connection between this repulsive solid–liquid interface will trigger the adhesion and increase the viscous shear force,for example,dispersant,hydrogen bondings,and shaky adsorbed water ***,the lamellar thickness of CuP and the molecular size of lubricant both have a great influence on tribological *** the lubrication mechanism based on interface Coulomb repulsion is proposed that may help broaden the scope of the exploration in low-friction nanomaterial design and new lubricant systems.

关键词： lubrication nanomaterial additive solid-liquid interface wear

Precipitation of α-Fe from Fe_(84-x)Si_(4)B_(12+x)(x=1,3) Amorphous Alloys Under High Magnetic Field Annealing

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Acta Metallurgica Sinica(English Letters) 2021年第8期34卷 1163-1172页

作者： Leipeng duan Kang Wang Engang Wang Peng jia Key Laboratory of Electromagnetic Processing of Materials(Ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China

This work aims to investigate the effects of high magnetic field annealing(HMFA) on the precipitation of α-Fe from Fe_(84-x)Si_(4)B_(12+ x)( x = 1, 3) amorphous precursors. Isothermal annealing process for Fe_(81)Si_(4)B_(15) and Fe_(83)Si_(4)B_(13) amorphous ribbons has been performed with and without the magnetic field. The magnetic field shows the effects of increasing the nucleation rate and decreasing the grain size of α-Fe crystals simultaneously, during the crystallization processes of the investigated amorphous alloys. By applying HMF, α-Fe crystals with more homogeneous distribution and smaller grain size are achieved in the amorphous matrix, which is crucial helpful to improve the magnetic properties for Fe–Si–B amorphous alloys. The mechanism of HMFA affecting the crystallization microstructure is also discussed in the present work.

关键词： High magnetic field Crystallization α-Fe Nucleation Grain size Atomic diffusion

Comparison of electrochemical behaviors of Ti-5Al-2Sn-4Zr-4Mo-2Cr-1Fe and Ti-6Al-4V titanium alloys in NaNO_(3) solution

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 750-763页

作者： jia Liu Shuanglu duan Xiaokang Yue Ningsong Qu College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

The Ti-5Al-2Sn-4Zr-4Mo-2Cr-1Fe(β-CEZ)alloy is considered as a potential structural material in the aviation industry due to its outstanding strength and corrosion *** machining(ECM)is an efficient and low-cost technology for manufacturing theβ-CEZ *** ECM,the machining parameter selection and tool design are based on the electrochemical dissolution behavior of the *** this study,the electrochemical dissolution behaviors of theβ-CEZ and Ti-6Al-4V(TC4)alloys in NaNO3solution are *** open circuit potential(OCP),Tafel polarization,potentiodynamic polarization,electrochemical impedance spectroscopy(EIS),and current efficiency curves of theβ-CEZ and TC4 alloys are *** results show that,compared to the TC4 alloy,the passivation film structure is denser and the charge transfer resistance in the dissolution process is greater for theβ-CEZ ***,the dissolved surface morphology of the two titanium-based alloys under different current densities are *** low current densities,theβ-CEZ alloy surface comprises dissolution pits and dissolved products,while the TC4 alloy surface comprises a porous honeycomb *** high current densities,the surface waviness of both the alloys improves and the TC4 alloy surface is flatter and smoother than theβ-CEZ alloy ***,the electrochemical dissolution models ofβ-CEZ and TC4 alloys are proposed.

关键词： electrochemical machining dissolution behavior β-CEZ titanium alloy polarization curve current efficiency