检索结果-南通市图书馆

Earth and Planetary Physics 2024年第2期8卷 408-414页

作者： Jun wu jian wu Jie Feng QingLiang Li ShuJi hao ZhengWen Xu HaiSheng Zhao YaBin Zhang National Key Laboratory of Electromagnetic Environment China Research Institute of Radio Wave PropagationBeijing 102206China School of Physics Xidian UniversityXi’an 710071China

During the course of ionospheric heating experiments, researchers at the European Incoherent Scatter Scientific Association (EISCAT) observed an apparent electron density enhancement. The enhancement extended over a wide range of altitudes, above the reflection altitude of the high-frequency pump wave. However, whether this enhancement actually corresponds to a true enhancement in electron density remains an open question. When the dispersion relation of ion acoustic waves is followed, the frequency ratio of the enhanced ion line to the background ion line suggests that the profile of the effective ion mass may have remained unchanged. Furthermore, the solar radio flux and ion drift velocity indicate no significant changes in the ion species and their densities. In conclusion, the electron density enhancement observed at EISCAT should not, in fact, be considered a true enhancement.

关键词： incoherent scatter radar(ISR) ionospheric heating electron density ion acoustic wave

维普期刊数据库

Diagnosis of poorly differentiated adenocarcinoma of the stomach by confocal laser endomicroscopy:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第8期12卷 1481-1486页

作者： jia-Xin Lou Yong wu Muren Huhe Jing-Jie Zhang Dong-wu jia Zhen-Yu jiang Department of Gastroenterology The Second Affiliated Hospital of Baotou Medical CollegeInner Mongolia University of Science and TechnologyBaotou 014030Inner Mongolia Autonomous RegionChina Medical Innovation Center The Fourth Military Medical UniversityXi'an 710000Shaanxi ProvinceChina

BACKGROUND In recent years,confocal laser endomicroscopy(CLE)has become a new endoscopic imaging technology at the microscopic level,which is extensively performed for real-time in vivo histological *** can be performed to distinguish benign from malignant *** this study,we diagnosed using CLE an asymptomatic patient with poorly differentiated gastric *** SUMMARY A 63-year-old woman was diagnosed with gastric mucosal lesions,which may be gastric cancer,in the small curvature of the stomach by *** consented to undergo CLE for morphological observation of the gastric *** the combination of CLE diagnosis and postoperative pathology,the intraoperative CLE diagnosis was considered to be *** to our experience,CLE can be performed as the first choice for the diagnosis of gastric *** CLE has several advantages over pathological *** believe that CLE has great potential in the diagnosis of benign and malignant gastric lesions.

关键词： Confocal laser endomicroscopy Poorly differentiated gastric adenocarcinoma Diagnosis Early stage Case report

Unlocking single-atom catalysts via amorphous substrates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第5期17卷 3533-3546页

作者： Bohua Sun Mingyuan Xu Xiaoxia Li Baohong Zhang Rui hao Xiaoyu Fan Binbin jia Dingshun She School of Engineering and Technology China University of Geosciences(Beijing)Beijing 100083China Zhengzhou Institute China University of Geosciences(Beijing)Zhengzhou 451283China College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China School of Chemistry Beihang UniversityBeijing 100191China Chinese Academy of Sciences(CAS)Key Laboratory of Nanosystem and Hierarchy Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China National Engineering Research Center of Nonferrous Metals Materials and Products for New EnergyChina GRINM Group Co.Ltd.Beijing 100088China

Single-atom catalysts(SACs)reveal great potential for application in catalysis due to their fully exposed active *** general,single atoms(SAs)and the coordination substrates need to have strong interactions or charge transfer to ensure the atomic dispersion,which requires the selection of a suitable substrate to stabilize the target *** studies have demonstrated that amorphous materials with abundant defects and coordinatively unsaturated sites can be used as substrates for more efficient capturing SAs,further enhancing the catalytic *** this review,we discuss recent research progress of SAs loaded on amorphous substrates for enhanced catalytic ***,we summarize the commonly used amorphous substrates for stabilizing ***,we present several advanced applications of amorphous SACs in the field of catalysis,including electrocatalysis and *** then,we also clarify the synergistic mechanism between SAs and amorphous substrate on catalytic ***,we summarize the challenges with our personal views and provide a critical outlook on how amorphous SACs continue to evolve.

关键词： single-atoms amorphous substrate synthetic strategy catalysis

Gigantic occipital epidermal cyst in a 56-year-old female:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第6期12卷 1169-1173页

作者： Yao Wei Peng Chen hao wu Department of Neurosurgery The Second Affiliated Hospital of Xi’an Medical UniversityXi'an 710038Shaanxi ProvinceChina

BACKGROUND Gigantic epidermal cysts(GECs)are rare benign skin appendicular tumours also known as *** have a high incidence and their wall is made up of *** cysts can occur in any part of the skin;clinical manifestations include skin colour hemispherical swelling;cystic;mobile;0.5 cm to several centimetres in diameter;and slow *** SUMMARY Herein,we report a case involving a 56-year-old female with a GEC in the *** July 25,2023,a patient with a GEC was admitted to the neurosurgery Department of the Second Affiliated Hospital of Xi'an Medical *** phyma was shown to be a solid mass during the operation and was confirmed to be a GEC based on pathological *** Epidermal cysts are common cystic nodules on the surface of the body,the aetiology is unclear,the clinical manifestations can vary,and the misdiagnosis rate is ***,giant epidermal cysts are *** most cases,however,the prognosis is *** paper analyses and summarizes the population,location,clinical and pathological characteristics and pathogenesis of the disease to strengthen the understanding of this disease and improve the accuracy of clinical diagnosis.

关键词： Epidermal cyst Occipital Brain Cyst Case report

A universal calibration method for eliminating topographydependent current in conductive AFM and its application in nanoscale imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第7期17卷 6509-6517页

作者： Chunlin hao hao Xu Shiquan Lin Yaju Zhang Jinmiao He Bei Liu Yuanzheng Zhang Banghao wu Guozhen Shen Haiwu Zheng Henan Province Engineering Research Center of Smart Micro-nano Sensing Technology and Application School of Physics and ElectronicsHenan UniversityKaifeng 475004China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 100083China

The topography and electrical properties are two crucial characteristics that determine the roles and functionalities of *** atomic force microscopy(CAFM)is widely recognized for its ability to independently measure the topography and *** increasing trend towards miniaturization in electrical devices and sensors has encouraged an urgent demand for enhancing the accuracy of CAFM ***,when performing CAFM tests on Bi_(0.5)Na_(0.5)TiO_(3)bulk ceramic,it is interesting to observe significant currents related to the *** do insulators exhibit“conductivity”in CAFM testing?Herein,we thoroughly investigated the topography-dependent current during CAFM testing for the first *** on the linear dependence between the current and the first derivative of topography,the calibration method has been proposed to eliminate the topographic *** method is evaluated on Bi_(0.5)Na_(0.5)TiO_(3)bulk ceramic,one-dimensional(1D)ZnO nanowire,twodimensional(2D)NbOI_(2)flake,and biological lotus *** corresponding results of negligible topography-interference current affirm the feasibility and universality of this calibration *** work effectively addresses the challenge of topographic crosstalk in CAFM characterization,thereby preventing the erroneous estimation of the conductivity of any unknown sample.

关键词： conductive atomic force microscopy topographic crosstalk current error calibration method

LncRNA HOTAIR promotes DNA damage repair and radioresistance by targeting ATR in colorectal cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第8期32卷 1335-1346页

作者： HAIQING HU hao YANG SHUAISHUAI FAN XUE jia YING Zhao HONGRUI LI Department of Endoscopic Center Peking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityHuhhot010020China Department of Radiation Oncology Peking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityKey Laboratory of Radiation Physics and Biology of Inner Mongolia Medical UniversityPeking University Cancer Hospital(Inner Mongolia Campus)&Affiliated Cancer Hospital of Inner Mongolia Medical UniversityHuhhot010020China Graduate School Inner Mongolia Medical UniversityHuhhot010020China

Long non-coding RNAs(lncRNAs)have been implicated in cancer progression and drug resistance ***,there is evidence that lncRNA HOX transcript antisense intergenic RNA(HOTAIR)is involved in colorectal cancer(CRC)*** present study aimed to examine the functional role of lncRNA HOTAIR in conferring radiotherapy resistance in CRC cells,as well as the underlying *** relative expression levels of HOTAIR were examined in 70 pairs of CRC tumor and para-cancerous tissues,as well as in radiosensitive and radioresistant *** correlations between HOTAIR expression levels and clinical features of patients with CRC were assessed using the Chi-square *** assays such as cell proliferation,colony formation and apoptosis assays were conducted to determine the radiosensitivity in CRC cells with HOTAIR silencing after treatment with different doses of *** pull-down assay andﬂuorescence in situ hybridization(FISH)were used to determine the interaction between HOTAIR and DNA damage response mediator ataxia-telangiectasia mutated-and Rad3-related(ATR).HOTAIR was signiﬁcantly upregulated in CRC tumor tissues,especially in radioresistant tumor *** elevated expression of HOTAIR was correlated with more advanced histological grades,distance metastasis and the poor prognosis in patients with *** HOTAIR suppressed the proliferation and promoted apoptosis and radiosensitivity in CRC *** knockdown also inhibited the tumorigenesis of CRC cells and enhanced the sensitivity to radiotherapy in a mouse xenograft ***,the data showed that HOTAIR could interact with ATR to regulate the DNA damage repair signaling *** HOTAIR impaired the ATR-ATR interacting protein(ATRIP)complex and signaling in cell cycle ***,the present results indicate that lncRNA HOTAIR facilitates the DNA damage response pathway and promotes radioresistance in CRC cells by targeting ATR.

关键词： LncRNA HOTAIR CRC radioresistance DNA damage repair ATR

Multiple types of disease-associated RNAs identification for disease prognosis and therapy using heterogeneous graph learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第8期67卷 341-342页

作者： Wenxiang ZHANG Hang WEI Wenjing ZHANG hao wu Bin LIU School of Computer Science and Technology Beijing Institute of Technology School of Computer Science and Technology Xidian University Department of Teaching and Research Shenzhen University General Hospital Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging National-Regional Key Technology Engineering Laboratory for Medical UltrasoundSchool of Biomedical Engineering Shenzhen University Medical School Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology

Identifying disease-associated RNAs is crucial in revealing the pathogenic mechanisms of diseases [1], and biologists have made notable progress in this field [2]. However, more effective computational methods are needed to provide reference disease-associated RNAs, reducing the manpower and material resources required for biological experiments.

关键词：

同方期刊数据库

Prognostic analysis of related factors of adverse reactions to immunotherapy in advanced gastric cancer and establishment of a nomogram model

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1268-1280页

作者： Xu-Xu He Bang Du Tao wu hao Shen Department of Surgery Fudan University Affiliated Zhongshan Hospital(Qingpu Branch)Shanghai 201700China Department of Surgery Anhui Provincial Red Cross Society HospitalHefei 230031Anhui ProvinceChina Department of General Surgery West China Hospital of Sichuan UniversityChengdu 610044Sichuan ProvinceChina

BACKGROUND Immunotherapy for advanced gastric cancer has attracted widespread attention in recent ***,the adverse reactions of immunotherapy and its relationship with patient prognosis still need further *** order to determine the association between adverse reaction factors and prognosis,the aim of this study was to conduct a systematic prognostic *** comprehensively evaluating the clinical data of patients with advanced gastric cancer treated by immunotherapy,a nomogram model will be established to predict the survival status of patients more *** To explore the characteristics and predictors of immune-related adverse reactions(irAEs)in advanced gastric cancer patients receiving immunotherapy with programmed death protein-1(PD-1)inhibitors and to analyze the correlation between irAEs and patient *** A total of 140 patients with advanced gastric cancer who were treated with PD-1 inhibitors in our hospital from June 2021 to October 2023 were *** were divided into the irAEs group and the non-irAEs group according to whether or not irAEs *** features,manifestations,and prognosis of irAEs in the two groups were collected and analyzed.A multivariate logistic regression model was used to analyze the related factors affecting the occurrence of irAEs,and the prediction model of irAEs was *** receiver operating characteristic(ROC)curve was used to evaluate the ability of different indicators to predict irAEs.A Kaplan-Meier survival curve was used to analyze the correlation between irAEs and *** Cox proportional risk model was used to analyze the related factors affecting the prognosis of *** A total of 132 patients were followed up,of whom 63(47.7%)developed *** looked at the two groups’clinical features and found that the two groups were statistically different in age≥65 years,Ki-67 index,white blood cell count,neutrophil count,and regulatory T cell(Treg)count

关键词： Advanced gastric cancer Prognostic analysis Immunotherapy Nomogram model

Assessing target optical camouflage effects using brain functional networks:A feasibility study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第4期34卷 69-77页

作者： Zhou Yu Li Xue Weidong Xu Jun Liu Qi jia jianghua Hu Jidong wu National Key Laboratory of Lightning Protection and Electromagnetic Camouflage Army Engineering University Nanjing 210007JiangsuChina Unit 31608 of PLA Xiamen 361000FujianChina School of Biological Sciences&Medical Engineering Southeast UniversityNanjing 210096JiangsuChina

Brain functional networks model the brain's ability to exchange information across different regions,aiding in the understanding of the cognitive process of human visual attention during target searching,thereby contributing to the advancement of camouflage *** this study,images with various camouflage effects were presented to observers to generate electroencephalography(EEG)signals,which were then used to construct a brain functional *** topological parameters of the network were subsequently extracted and input into a machine learning model for *** results indicate that most of the classifiers achieved accuracy rates exceeding 70%.Specifically,the Logistic algorithm achieved an accuracy of 81.67%.Therefore,it is possible to predict target camouflage effectiveness with high accuracy without the need to calculate discovery *** proposed method fully considers the aspects of human visual and cognitive processes,overcomes the subjectivity of human interpretation,and achieves stable and reliable accuracy.

关键词： Camouflage effect evaluation Electroencephalography(EEG) Brain functional networks Machine learning

维普期刊数据库

Numerical investigation of hydro-morphodynamic characteristics of a cascading failure of landslide dams

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第6期21卷 1868-1885页

作者： ZHONG Qiming CHEN Lingchun MEI Shengyao SHAN Yibo wu hao Zhao Kunpeng Department of Geotechnical Engineering Nanjing Hydraulic Research InstituteNanjing 210024China National Key Laboratory of Water Disaster Prevention Nanjing 210098China Key Laboratory of Reservoir and Dam Safety of the Ministry of Water Resources Nanjing 210029China

A cascading failure of landslide dams caused by strong earthquakes or torrential rains in mountainous river valleys can pose great threats to people’s lives,properties,and *** this study,based on the three-dimensional Reynoldsaveraged Navier-Stokes equations(RANS),the renormalization group(RNG)k-εturbulence model,suspended and bed load transport equations,and the instability discriminant formula of dam breach side slope,and the explicit finite volume method(FVM),a detailed numerical simulation model for calculating the hydro-morphodynamic characteristics of cascading dam breach process has been *** developed numerical model can simulate the breach hydrograph and the dam breach morphology evolution during the cascading failure process of landslide dams.A model test of the breaches of two cascading landslide dams has been used as the validation *** comparison of the calculated and measured results indicates that the breach hydrograph and the breach morphology evolution process of the upstream and downstream dams are generally consistent with each other,and the relative errors of the key breaching parameters,i.e.,the peak breach flow and the time to peak of each dam,are less than±5%.Further,the comparison of the breach hydrographs of the upstream and downstream dams shows that there is an amplification effect of the breach flood on the cascading landslide dam *** key parameters,i.e.,the distance between the upstream and the downstream dams,the river channel slope,and the downstream dam height,have been used to study the flood amplification *** parameter sensitivity analyses show that the peak breach flow at the downstream dam decreases with increasing distance between the upstream and the downstream dams,and the downstream dam ***,the peak breach flow at the downstream dam first increases and then decreases with steepening of the river channel *** the flood caused by the upstream dam failure flows to the

关键词： Cascading landslide dams Cascading dam failure process Detailed numerical simulation model Flood amplification effect Parameter sensitivity analyses

维普期刊数据库