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An improved typhoon monitoring model based on precipitable water vapor and pressure

Geodesy and Geodynamics 2024年第3期15卷 276-290页

作者： Junyu li Haojie li lilong liu jiaqing Chen Yibin Yao Mingyun Hu liangke Huang Fade Chen Tengxu Zhang Lv Zhou College of Geomatics and Geoinformation Guilin University of TechnologyGuilin 541006China Guangxi Key Laboratory of Spatial Information and Geomatics Guilin 541006China Qinzhou Institute of Surveying and Mapping for Housing and Urban-Rural Development Co. Ltd.Qinzhou 535000China School of Geodesy and Geomatics Wuhan UniversityWuhan 430079China School of Resources and Environmental Science and Engineering Hubei University of Science and TechnologyXianning 437100China

The potential of monitoring the movement of typhoons using the precipitable water vapor(PWV) has been confirmed. However, monitoring the movement of typhoon is focused on PWV, making it difficult to describe the movement of a typhoon in detail minutely and resulting in insufficient accuracy. Hence,based on PWV and meteorological data, we propose an improved typhoon monitoring mode. First, the European Centre for Medium-Range Weather Forecasts Reanalysis 5-derived PWV(ERA5-PWV) and the Global Navigation Satellite System-derived PWV(GNSS-PWV) were compared with the reference radiosonde PWV(RS-PWV). Then, using the PWV and atmospheric parameters derived from ERA5, we discussed the anomalous variations of PWV, pressure(P), precipitation, and wind speed during different typhoons. Finally, we compiled a list of critical factors related to typhoon movement, PWV and P. We developed an improved multi-factor typhoon monitoring mode(IMTM) with different models(i.e.,IMTM-I and IMTM-II) in different cases with a higher density of GNSS observation or only Numerical Weather Prediction(NWP) data. The IMTM was evaluated through the reference movement speeds of HATO and Mangkhut from the China Meteorological Observatory Typhoon Network(CMOTN). The results show that the root mean square(RMS) of the IMTM-I is 1.26 km/h based on ERA5-P and ERA5-PWV,and the absolute bias values are mostly within 2 km/h. Compared with the models considering the single factor ERA5-P/ERA5-PWV, the RMS of the IMTM-I is improved by 26.3% and 38.5%, respectively. The IMTM-II model manifests a residual of only 0.35 km/h. Compared with the single-factor model based on GNSS-PWV/P, the residual of the IMTM-II model is reduced by 90.8% and 84.1%, respectively. These results propose that the typhoon movement monitoring approach combining PWV and P has evident advantages over the single-factor model and is expected to supplement traditional typhoon monitoring.

关键词： Typhoon GNSS/ERA5 PWV Pressure Monitoring Improved model

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Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties

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Military Medical Research 2024年第4期11卷 543-566页

作者： ying Chen Xing Wang Sheng Tao Qi Wang Pan-Qin Ma Zi-Biao li Yun-Long Wu Da-Wei li Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology School of Pharmaceutical SciencesXiamen UniversityXiamen 361102FujianChina Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100090China University of Chinese Academy of Sciences Beijing 100049China Senior Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijing 100091China Institute of Materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)Singapore 138634Singapore

The treatment of chronic and non-healing wounds in diabetic patients remains a major medical *** reports have shown that hydrogel wound dressings might be an effective strategy for treating diabetic wounds due to their excellent hydrophilicity,good drug-loading ability and sustained drug release *** a typical example,hyaluronic acid dressing(Healoderm)has been demonstrated in clinical trials to improve wound-healing efficiency and healing rates for diabetic foot ***,the drug release and degradation behavior of clinically-used hydrogel wound dressings cannot be adjusted according to the wound *** to the intricacy of diabetic wounds,antibiotics and other medications are frequently combined with hydrogel dressings in clinical practice,although these medications are easily hindered by the hostile *** this case,scientists have created responsive-hydrogel dressings based on the microenvironment features of diabetic wounds(such as high glucose and low pH)or combined with external stimuli(such as light or magnetic field)to achieve controllable drug release,gel degradation,and microenvironment improvements in order to overcome these clinical *** responsive-hydrogel dressings are anticipated to play a significant role in diabetic therapeutic wound ***,we review recent advances on responsive-hydrogel dressings towards diabetic wound healing,with focus on hydrogel structure design,the principle of responsiveness,and the behavior of *** but not least,the advantages and limitations of these responsive-hydrogels in clinical applications will also be *** hope that this review will contribute to furthering progress on hydrogels as an improved dressing for diabetic wound healing and practical clinical application.

关键词： Responsive-hydrogel Diabetic wound Anti-inflammation Tissue remodeling

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Toeless and reversible DNA strand displacement based on Hoogsteen-bond triplex

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Chinese Chemical Letters 2024年第5期35卷 330-337页

作者： Yang Qin jiangtian li Xuehao Zhang Kaixuan Wan Heao Zhang Feiyang Huang limei Wang Hongxun Wang Longjie li Xianjin Xiao Institute of Reproductive Health Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Pancreatic Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Wuhan Polytechnic University Wuhan 430023China

Strand displacement reaction is a crucial component in the assembly of diverse DNA-based nanodevices,with the toehold-mediated strand displacement reaction representing the prevailing ***,the single-stranded Watson-Crick sticky region that serves as the trigger for strand displacement can also cause leakage reactions by introducing crosstalk in complex DNA ***,we proposed the toeless and reversible DNA strand displacement reaction based on the Hoogsteen-bond triplex,which is compatible with most of the existing DNA *** demonstrated that our proposed reaction can occur at pH 5 and can be reversed at pH *** also observed an approximately linear relationship between the degree of reaction and pH within the range of pH 5-6,providing the potential for precise regulation of the ***,by altering the sequence orientation,we have demonstrated that our proposed reaction can be initiated or regulated through the same toeless mechanism without the requirement for protonation in low pH *** on the proposed reaction principle,we further constructed a variety of DNA nanodevices,including two types of DNA logic gates that rely on pH 5/pH 9 changes for initiating and reversing:the AND gate and the OR *** also successfully constructed a DNA Walker based on our proposed reaction modes,which can move along a given track after the introduction of a programmable DNA sequence and complete a cycle after 4 *** findings suggest that this innovative approach will have broad utility in the development of DNA circuits,molecular sensors,and other complex biological systems.

关键词： DNA strand displacement Toeless Triplex DNA strands Reversible DNA circuit DNA walker

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Exploring the role of iron in Fe_(5)Ni_(4)S_(8)toward oxygen evolution through modulation of electronic orbital occupancy

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Journal of Energy Chemistry 2024年第5期92卷 52-62页

作者： Zhengyan Du Zeshuo Meng Haoteng Sun Yifan li Chao jiang Yaxin li Xiaoying Hu Yi Cui Shansheng Yu Hongwei Tian Key Laboratory of Automobile Materials of MOE School of Materials Science and EngineeringJilin UniversityChangchun 130012JilinChina College of Science and Laboratory of Materials Design and Quantum Simulation Changchun UniversityChangchun 130022JilinChina i-lab Vacuum Interconnected Nanotech Workstation(Nano-X)Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123JiangsuChina Department of Chemistry Brown UniversityRI 02912United States

Ni-Fe-based catalysts are considered to be among the most active catalysts for the oxygen evolution reaction(OER)under alkaline conditions,with Fe playing a crucial ***,Fe leaching occurs during the reaction due to thermodynamic instability,which has resulted in conflicting reports within the literature regarding its *** clarify this point,we propose a strategy consisting of modulating the electronic orbital occupancy to suppress the extensive loss of Fe atoms during the OER *** calculations,in-situ X-ray photoelectron spectroscopy,molecular dynamics simulations,and a series of characterization showed that the stable presence of Fe not only accelerates the electron transfer process but also optimizes the reaction barriers of the oxygen evolution intermediates,promoting the phase transition of Fe_(5)Ni_(4)S_(8)to highly active catalytic *** modulated Fe_(5)Ni_(4)S_(8)-based pre-catalysts exhibit improved OER activity and long-term *** study provides a novel perspective for understanding the role of Fe in the OER process.

关键词： Oxygenevolution Fe_(5)Ni_(4)S_(8) Electronic orbital occupancy modulation Reconstruction dynamics

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Magmatic-tectonic response of the South China Craton to the Paleo-Pacific subduction during the Triassic:a new viewpoint based on Well NK-1

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Journal of Oceanology and limnology 2024年第1期42卷 58-89页

作者： Chan WANG Hao liU Gang li Zhen SUN Tingting GONG li MIAO Xiaowei ZHU Yunying ZHANG Weihai XU Wen YAN Key Laboratory of Ocean and Marginal Sea Geology South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China Key Laboratory of Tectonic Controlled Mineralization and Oil Reservoir of Ministry of Natural Resources Chengdu University of TechnologyChengdu 610059China School of Earth Sciences and Resources China University of Geosciences(Beijing)Beijing 100083China College of Earth Science Chengdu University of TechnologyChengdu 610059China University of Chinese Academy of Sciences Beijing 100049China

The Nansha Block(NB)is one of the blocks separated from the southern margin of the South China Craton(SCC)by the western Pacific subduction,which contains rich information of geodynamic and tectonic *** reveal the essence of western Paleo-Pacific subduction during the Triassic period,Well NK-1 in this block was selected for petrographic study,and published research data from other cooperative teams were compared.A double-cycle pattern of basic to neutral magmatic volcanism was established,and 36 lithological rhythmic layers and representative cryptoexplosive breccia facies and welded tuff bands were *** with a reanalysis of published geochronological data,geochemical elements,and isotope geochemistry,we found that the rock assemblages could be divided into an intermediate-acid dacite(DA)series(SiO_(2)>65%)and basaltic(BA)series(Coline island-arc magmatic properties:(^(87)Sr/^(86)Sr)_i ratio ranging 0.70377–0.71118(average:0.70645),^(147)Sm/^(144)Nd ratio ranging 0.119–0.193(average:0.168),and chondrite-normalized rare earth element(REE)curves being flat,while DA exhibits remarkable characteristics of subducted island-arc andesitic magma:(^(87)Sr/^(86)Sr)_i ratio(0.70939–0.71129;average:0.71035),εNd(t)value(-6.2–-4.8;average:-5.6)andε_(Hf)(t)value(-2.9–-1.7,average:-2.2)show obvious crust-mantle mixing *** and DA reveal typical characteristics of island-arc magma systems and typeⅡenriched mantle(EM-Ⅱ)*** magma was likely resulted from the process whereby the continental crust frontal accretionary wedge was driven by the Paleo-Pacific slab subduction into the deep and began to melt,resulting in a large amount of melt(fluid)joined the asthenosphere on the side of the continental *** contrast,DA magma was likely resulted from the process whereby the plate front was forced to bend with increasing subducti

关键词： Paleo-Pacific tectonic domain tectonic evolution rift volcanic rock Nansha Block South China Craton

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Correlation between circulating T follicular helper cell levels after infection and a decreased risk of COVID-19 re-infection

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Virologica Sinica 2024年第4期39卷 699-701页

作者： Jinzhu Feng Zeyu Pu Rong li Yuzhuang li Xuewen Qin Hui Zhang Yiwen Zhang Institute of Human Virology Department of Pathogen Biology and BiosecurityKey Laboratory of Tropical Disease Control of Ministry of EducationZhongshan School of MedicineSun Yat-sen UniversityGuangzhou510080China

Dear Editor,As mass vaccination has been accomplished worldwide and a growing number of individuals have already been infected by SARS-CoV-2,understanding the incidence of subsequent re-infection is urgently required for comprehending the transmission dynamics of COVID-19(Bobrovitz et al.,2023).Additionally,current SARS-CoV-2 variants cause widespread escape from the neutralizing antibody(nAb)elicited by current ***,durable neutralization and memory B cell responses can be predicted by rapid CD4t T cell responses,particularly strong circulating T follicular helper(cTfh)cell responses,in individuals infected with SARS-CoV-2(Gong et al.,2020;Boppana et al.,2021;Narowski et al.,2022).Although nAb titers are known as predictors of protection against SARS-CoV-2 variants(Khoury et al.,2021),identifying more potential factors that could predict the risk of re-infection following primary infection and vaccination has become quite important in shaping prevention strategies(Chemaitelly et al.,2023).

关键词： infection prevention subsequent

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鲜人参中丙二酰基人参皂苷-Ra_(1)、-Ra_(2)的分离及结构鉴定

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中国中药杂志 2024年第12期49卷 3252-3257页

作者：李泽文李丹李嘉星崔颖陆雅倩刘志吉林农业大学中药材学院吉林长春130118

该文旨在对鲜人参Panax ginseng根中的丙二酰基人参皂苷类化学成分进行研究。通过D101大孔吸附树脂柱、ODS柱色谱及高效液相色谱制备分离技术等方法,对鲜人参根中70%乙醇提取物的化学成分进行分离纯化,并通过高分辨质谱和核磁共振波谱... 详细信息

该文旨在对鲜人参Panax ginseng根中的丙二酰基人参皂苷类化学成分进行研究。通过D101大孔吸附树脂柱、ODS柱色谱及高效液相色谱制备分离技术等方法,对鲜人参根中70%乙醇提取物的化学成分进行分离纯化,并通过高分辨质谱和核磁共振波谱相结合的方法对化合物进行结构鉴定。从鲜人参提取物中分离得到2个丙二酰基人参皂苷,分别鉴定为3-O-[6-O-丙二酰基-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃木糖基-(1→4)-α-L-吡喃阿拉伯糖基-(1→6)-β-D-吡喃葡萄糖基]-达玛-24-烯-3β,12β,20S-三醇(1)和3-O-[6-O-丙二酰基-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基]-20-O-[β-D-吡喃木糖基-(1→2)-α-L-呋喃阿拉伯糖基-(1→6)-β-D-吡喃葡萄糖基]-达玛-24-烯-3β,12β,20S-三醇(2)。化合物1和2为首次从人参根中分离得到的新化合物,分别命名为丙二酰基人参皂苷-Ra_(1)(malonyl ginsenoside-Ra_(1))和丙二酰基人参皂苷-Ra_(2)(malonyl ginsenoside-Ra_(2))。

关键词：人参丙二酰基人参皂苷-Ra_(1) 丙二酰基人参皂苷-Ra_(2) 结构鉴定

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Review of the SiC LDMOS power device

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Journal of Semiconductors 2024年第8期45卷 4-17页

作者： Ziwei Hu jiafei Yao Ang li Qi Sun Man li Kemeng Yang Jun Zhang Jing Chen Maolin Zhang Yufeng Guo College of Integrated Circuit Science and Engineering(Industry-Education Integration School) Nanjing University of Posts andT elecommunicationsNanjing 210023China National and Local Joint Engineering Laboratory of RF Integration and Micro-Assembly Technology Nanjing 210023China Nantong Institute of Nanjing University of Posts and Telecommunications Nantong 226000China

Silicon carbide(SiC),as a third-generation semiconductor material,possesses exceptional material properties that significantly enhance the performance of power *** SiC lateral double-diffused metal–oxide–semiconductor(LDMOS)power devices have undergone continuous optimization,resulting in an increase in breakdown voltage(BV)and ultra-low specific on-resistance(Ron,sp).This paper has summarized the structural optimizations and experimental progress of SiC LDMOS power devices,including the trench-gate technology,reduced surface field(RESURF)technology,doping technology,junction termination techniques and so *** paper is aimed at enhancing the understanding of the operational mechanisms and providing guidelines for the further development of SiC LDMOS power devices.

关键词： SiC LDMOS specific on-resistance breakdown voltage

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GmSTF accumulation mediated by DELLA protein GmRGAs contributes to coordinating light and gibberellin signaling to reduce plant height in soybean

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The Crop Journal 2024年第2期12卷 432-442页

作者： Zhuang li Qichao Tu Xiangguang Lyu Qican Cheng Ronghuan Ji Chao Qin Jun liu Bin liu Hongyu li Tao Zhao State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China

Plant height influences plant architecture,lodging resistance,and yield *** is modulated by gibberellic acid(GA)metabolism and *** proteins,acting as central repressors of GA signaling,integrate various environmental and hormonal signals to regulate plant growth and development in *** examined the role of two DELLA proteins,GmRGAa and GmRGAb,in soybean plant height *** of these proteins led to longer internodes and increased plant height,primarily by increasing cell *** functioned under different light conditions,including red,blue,and far-red light,to repress plant *** studies revealed that GmRGAs interacted with the blue light receptor *** with this,GmCRY1b partially regulated plant height via ***,DELLA proteins were found to stabilize the protein GmSTF1/2,a key positive regulator of *** stabilization led to increased transcription of GmGA2ox-7b and subsequent reduction in plant *** study enhances our understanding of DELLA-mediated plant height control,offering Gmrgaab mutants for soybean structure and yield optimization.

关键词： DELLA protein GmRGAs GmSTFs Plant height Soybean

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Improved genome annotation of Brassica oleracea highlights the importance of alternative splicing

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Horticultural Plant Journal 2024年第4期10卷 961-970页

作者： yinqing Yang Lei Zhang Qi Tang lingkui Zhang Xing li Shumin Chen Kang Zhang ying li Xilin Hou Feng Cheng State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjing 210095China State Key Laboratory of Vegetable Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesKey Laboratory of Biology and Genetic Improvement of Horticultural Crops of the Ministry of Agriculture and Rural AffairsSino-Dutch Joint Laboratory of Horticultural GenomicsBeijing 100081China

Brassica oleracea has been developed into many important crops,including cabbage,kale,cauliflower,broccoli and so *** genome and gene annotation of cabbage(cultivar JZS),a representative morphotype of ***,has been widely used as a common reference in biological *** its genome assembly has been updated twice,the current gene annotation still lacks information on untranslated regions(UTRs)and alternative splicing(AS).Here,we constructed a high-quality gene annotation(JZSv3)using a full-length transcriptome acquired by nanopore sequencing,yielding a total of 59452 genes and 75684 ***,we re-analyzed the previously reported transcriptome data related to the development of different tissues and cold response using JZSv3 as a reference,and found that 3843 out of 11908 differentially expressed genes(DEGs)underwent AS during the development of different tissues and 309 out of 903 cold-related genes underwent AS in response to cold ***,we also identified many AS genes,including BolLHCB5 and BolHSP70,that displayed distinct expression patterns within variant transcripts of the same gene,highlighting the importance of JZSv3 as a pivotal reference for AS ***,JZSv3 provides a valuable resource for exploring gene function,especially for obtaining a deeper understanding of AS regulation mechanisms.

关键词： Brassica oleracea Oxford nanopore technologies Gene annotation Alternative splicing

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