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利用离子阻停对电子俘获致核激发的研究

物理学报 2024年第13期73卷 101-110页

作者：贾晨旭丁兵滑伟郭松强赟华陈红星韦锐周小红中国科学院近代物理研究所兰州730000 中国科学院大学核科学与技术学院北京100049 中山大学中法核工程与技术学院珠海519082 广西师范大学物理科学与技术学院桂林541004

当特定能量的自由电子被原子核外电子轨道俘获时,有可能导致原子核被共振激发,这就是电子俘获致核激发.该机制的一个应用愿景是通过操纵电子使同核异能态所储存的核能按照人们的需求释放出来.如果能够实现这种技术,有望为核能的储存和... 详细信息

当特定能量的自由电子被原子核外电子轨道俘获时,有可能导致原子核被共振激发,这就是电子俘获致核激发.该机制的一个应用愿景是通过操纵电子使同核异能态所储存的核能按照人们的需求释放出来.如果能够实现这种技术,有望为核能的储存和利用带来巨大变革.本文对比了近年来基于加速器装置,在高电荷态离子阻停过程中测量电子俘获致核激发几率的两次实验研究工作.对于两次测量结果的不一致,从误差水平评估这一个新的角度分析了可能的原因.此外,通过评估四种可能的熔合蒸发反应道,发现94Zr束流和氦气靶可能是利用次级束开展下一步实验工作的理想弹靶组合.

关键词：同核异能态电子俘获致核激发诱发退激次级束伽马谱学

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批判与建构:高兹的经济理性批判

哈尔滨学院学报 2024年第4期45卷 11-15页

作者：徐嘉晨李国锋山东农业大学马克思主义学院山东泰安271018

安德烈·高兹是生态学马克思主义学派的主要代表人物之一,他的经济理性批判理论对建设生态社会有着重要作用。高兹的经济理性批判理论深刻阐述了处于经济理性支配下的现代资本主义社会面临的生态问题和社会问题,提出破除经济理性、建立... 详细信息

安德烈·高兹是生态学马克思主义学派的主要代表人物之一,他的经济理性批判理论对建设生态社会有着重要作用。高兹的经济理性批判理论深刻阐述了处于经济理性支配下的现代资本主义社会面临的生态问题和社会问题,提出破除经济理性、建立生态理性的主张和“更少但是更好”的理念,并认为实现人与自然和谐统一的最佳路径就是建立生态社会主义制度。

关键词：安德烈·高兹生态社会主义经济理性批判

Quantitative Analysis of Frosting Characteristics on the Drip Tray of A Cryogenic Valve for LNG Ships

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China Ocean Engineering 2024年第4期38卷 572-585页

作者： BAI xu chen Guan-yu DU Yue xu Cao chen jia-jing School of Naval Architecture&Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

Cryogenic valves play a crucial role in the production and transportation of liquefied natural gas(LNG),and are primarily responsible for efficiently controlling the inflow and outflow of LNG and regulating ***,due to their operation in low-temperature and high-humidity environments,crucial components such as drip trays are susceptible to frosting,which may lead to LNG leakage,thereby causing severe safety *** this study,the user-defined function(UDF)is employed to redevelop Fluent,which integrates the frost growth model with the Eulerian multiphase flow model,to conduct a quantitative analysis of frosting on drip trays of cryogenic *** effects of environmental parameters,such as wind speed,ambient temperature,air humidity,and cold surface temperature on the growth of the frost layer were *** study reveals a limiting wind speed between 1 m/s and 2 m/*** reaching this limit speed,the growth of the frost layer reaches its maximum,and further increases in the wind speed have no significant effect on the growth of the frost ***,the influence of the change in the flow field on droplet impingement and freezing during the growth of the frost layer is considered through the coupling method of the kinematic characteristics of water droplets and the collection coefficient of water *** study identifies the influence of different parameters on the droplet impact efficiency,leading to the modification of the frost layer on the drip tray.

关键词： LNG carrier drip tray frost effective impact coefficient

Profiling B and T cell immune responses to co-infection of Mycobacterium tuberculosis and hookworm in humans

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Infectious Diseases of Poverty 2015年第1期4卷 133-142页

作者： Xin-xu Li jia-xu chen Li-Xia Wang Jun Sun Shao-Hong chen Jun-Hu chen Xiao-Yan Zhang Xiao-Nong Zhou National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionKey Laboratory of Parasite and Vector BiologyMinistry of HealthWHO Collaborating Centre for MalariaSchistosomiasis and Filariasis207 Rui Jin Er RoadHuangpu DistrictShanghai 200025PR China(PRC) National Center for Tuberculosis Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206PR China Shanghai Public Health Clinical Center Key Laboratory of Medical Molecular Virology of Ministry of EducationInstitutes of Biomedical SciencesFudan UniversityShanghai 201508PR China

Background:Humoral and cellular immune responses play protective roles against Mycobacterium tuberculosis(MTB)***,hookworm infection decreases the immune response to hookworm and bystander ***,immune responses to co-infection of MTB and hookworm are still unknown,although co-infection has been one of the public health problems in co-endemic areas of pulmonary tuberculosis(PTB)and hookworm ***,it is essential to evaluate B and T cell immune responses to the ***:Seventeen PTB cases co-infected with hookworm,26 PTB cases,15 patients with hookworm infection,and 24 healthy controls without PTB or hookworm infection were enrolled in the *** of CD3,CD4,CD8,CD10,CD19,CD20,CD21,CD25,CD27,CD38,FoxP3,and PD-1 were assessed on B and T cell subsets using multicolor flow ***:For the B cell(CD19+)subsets,naïve B cells(CD10−CD27−CD21+CD20+),plasma cells(CD10−CD27+CD21−CD20−),and tissue-like memory B cells(CD10−CD27−CD21−CD20+)had higher proportions,whilst resting memory B cells(CD10−CD27+CD21+CD20+)had lower proportions in the group co-infected with MTB and hookworm as compared to other *** of activated memory B cells(CD10−CD27+CD21−CD20+)did not differ among the four *** the T cell(CD3+)subsets,frequencies of regulatory T cells(CD4+CD25+Foxp3+)and exhausted CD4+and CD8+T cells(CD4+PD-1+and CD8+PD-1+)were higher,and frequencies of activated CD4+and CD8+T cells(CD4+CD38+and CD8+CD38+)were lower in the co-infected group as compared to the other ***:The change patterns of the cell profile of circulating lymphocytes were indentified in human co-infection of MTB and hookworm,which might indicate that the humoral and cellular immune responses are more suppressed.

关键词： Co-infection Mycobacterium tuberculosis Hookworm Immune response

Cross-strait parasitological research priorities arrived at by historical tracking and advanced dialogue

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Infectious Diseases of Poverty 2014年第1期3卷 367-373页

作者： Jyh-Wei Shin jia-xu chen Dong-Hui Zhang Wei-chen Lin Bo Shen Min-Jun Ji Department of Parasitology National Cheng Kung UniversityTainanTaiwanChina The National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghaiChina Department of Pathogen Biology Nanjing Medical UniversityNanjingJiangsuChina

To further enhance dialogue and promote cross-strait cooperation in the prevention and control of parasitic diseases,this paper reviewed the progress and current challenges in the cross-strait control and research of parasitic infections,based on three cross-strait meetings on parasitological research in the last *** major outcome of the 3rd Meeting of Cross-Strait Parasitological Research held in April 2013 was identifying the research priorities for parasitological research.

关键词： Cross-strait meeting Parasitological research priorities Epidemiology

A mutation in the promoter of the yellow stripe-like transporter gene in cucumber results in a yellow cotyledon phenotype

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Journal of Integrative Agriculture 2024年第3期23卷 849-862页

作者： jiawei Pan jia Song Rahat Sharif xuewen xu Shutong Li xuehao chen School of Horticulture and Landscape Architecture Yangzhou UniversityYangzhou 225009China Institute of Vegetables Tianjin Academy of Agricultural SciencesTianjin 300384China

Leaf color mutants in higher plants are considered to be ideal materials for studying the chlorophyll biosynthesis,photosynthesis mechanism and chloroplast ***,we identified a spontaneous mutant,yc412,in cultivated cucumber that exhibited yellow *** yellow-lethal mutant was diagnosed with an abnormal chloroplast ultrastructure,and reduced photosynthetic capacity and pigment *** bulked segregant analysis-based whole-genome sequencing and fine genetic mapping,we narrowed the yellow cotyledons (yc) locus to a 96.8 kb interval on chromosome *** resequencing and molecular cloning,we showed that Csyc is a potential candidate gene,which encodes a yellow stripe-like (YSL) *** T to C mutation in the promoter region of Csyc caused the yellow cotyledon phenotype in *** to YZU027A (WT),the expression of Csyc was significantly downregulated in the cotyledons of *** of Csyc in cucumber via virus-induced gene silencing resulted in chlorotic leaves,mainly by suppressing the chlorophyll ***,a comparative transcriptome analysis revealed that chloroplast-related genes and chlorophyll biosynthesis genes were significantly downregulated in yc412 *** results provide new insights into the molecular function of the YSL transporter in plant chloroplast development and chlorophyll synthesis.

关键词： cucumber yellow-lethal cotyledons chloroplast development yellow stripe-like transporter

Response characteristics of PWR primary circuit under SBLOCAs considering steam bypass discharging

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Nuclear Science and Techniques 2024年第6期35卷 189-201页

作者： Shuai Yang Xiang-Bin Li Yu-Sheng Liu jia-Ning xu De-chen Zhang School of Nuclear Science and Engineering North China Electric Power UniversityBeijing 102206China Beijing Key Laboratory of Passive Safety Technology for Nuclear Energy Beijing 102206China Nuclear and Radiation Safety Center MEPBeijing 100084China

Small-break superposed station blackout(SBO)accidents are the basic design accidents of nuclear power *** the condition of a small break in the cold leg,SBO further increases the severity of the accident,and the steam bypass discharg-ing system(GCT)in the second circuit can play an important role in guaranteeing core *** explore the influence of the GCT on the thermal-hydraulic characteristics of the primary circuit,RELAP5 software was used to establish a numerical model based on a typical pressurized water reactor nuclear power *** different small breaks in the cold-leg super-posed SBO were selected,and the impact of the GCT operation on the transient response characteristics of the primary and secondary circuit systems was *** results show that the GCT plays an indispensable role in core heat removal during an accident;otherwise,core safety cannot be *** GCT was used in conjunction with the primary safety injection system during the placement *** the break diameter was greater than a certain critical value,the core cooling rate could not be guaranteed to be less than 100 K/h;however,the core remained in a safe state.

关键词： Steam bypass discharging Pressurized water reactor SBLOCA Numerical simulation

Risk factors,prognostic factors,and nomograms for distant metastasis in patients with diagnosed duodenal cancer:A population-based study

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1384-1420页

作者： jia-Rong Shang chen-Yi xu Xiao-xue Zhai Zhe xu Jun Qian Department of Oncology Jiangsu Province Hospital of Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Proctology Nanjing Hospital of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Digestive Cancer Surgery Jiangsu Province Hospital of Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina

BACKGROUND Duodenal cancer is one of the most common subtypes of small intestinal cancer,and distant metastasis(DM)in this type of cancer still leads to poor *** nomograms have recently been used in tumor areas,no studies have focused on the diagnostic and prognostic evaluation of DM in patients with primary duodenal *** To develop and evaluate nomograms for predicting the risk of DM and person-alized prognosis in patients with duodenal *** Data on duodenal cancer patients diagnosed between 2010 and 2019 were extracted from the Surveillance,Epidemiology,and End Results *** and multivariate logistic regression analyses were used to identify independent risk factors for DM in patients with duodenal cancer,and univariate and multivariate Cox proportional hazards regression analyses were used to determine independent prognostic factors in duodenal cancer patients with *** novel nomograms were established,and the results were evaluated by receiver operating characteristic(ROC)curves,calibration curves,and decision curve analysis(DCA).RESULTS A total of 2603 patients with duodenal cancer were included,of whom 457 cases(17.56%)had DM at the time of *** analysis revealed independent risk factors for DM in duodenal cancer patients,including gender,grade,tumor size,T stage,and N stage(P<0.05).Univariate and multivariate COX analyses further identified independent prognostic factors for duodenal cancer patients with DM,including age,histological type,T stage,tumor grade,tumor size,bone metastasis,chemotherapy,and surgery(P<0.05).The accuracy of the nomograms was validated in the training set,validation set,and expanded testing set using ROC curves,calibration curves,and DCA *** results of Kaplan-Meier survival curves(P<0.001)indicated that both nomograms accurately predicted the occurrence and prognosis of DM in patients with duodenal *** The two nomograms are expected as effective tools fo

关键词： Duodenal cancer Distant metastasis Nomogram Risk factors Prognostic factors

Xiaoyao San,a Chinese herbal formula,ameliorates depression-like behavior in mice through the AdipoR1/AMPK/ACC pathway in hypothalamus

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Journal of Integrative Medicine 2022年第5期20卷 442-452页

作者： Kai-rui Tang Xiao-wei Mo Xing-yi Zhou Yue-yue chen Dong-dong Liu Liang-liang He Qing-yu Ma Xiao-juan Li jia-xu chen Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine School of Traditional Chinese MedicineJinan UniversityGuangzhou 510632Guangdong ProvinceChina College of Pharmacy Jinan UniversityGuangzhou 510632Guangdong ProvinceChina

Objective Depression and metabolic disorders have overlapping psychosocial and pathophysiological *** research is focused on the possible role of adiponectin in regulating common biological *** San(XYS),a classic Chinese medicine compound,has been widely used in the treatment of depression and can alleviate metabolic disorders such as lipid or glucose metabolism ***,the ability of XYS to ameliorate depression-like behavior as well as metabolic dysfunction in mice and the underlying mechanisms are *** An in vivo animal model of depression was established by chronic social defeat stress(CSDS).XYS and fluoxetine were administered by gavage to the drug intervention ***-like behaviors were analyzed by the social interaction test,open field test,forced swim test,and elevated plus maze *** levels were measured using the oral glucose tolerance *** involvement of certain molecules was validated by immunofluorescence,histopathology,and Western *** vitro,hypothalamic primary neurons were exposed to high glucose to induce neuronal damage,and the neuroprotective effect of XYS was evaluated by cell counting kit-8 *** and Western blotting were used to evaluate the influences of XYS on adiponectin receptor 1(AdipoR1),adenosine 5’-monophosphate-activated protein kinase(AMPK),acetyl-coenzyme A carboxylase(ACC)and other related *** XYS ameliorated CSDS-induced depression-like behaviors and glucose tolerance impairment in mice and increased the level of serum *** also restored Nissl bodies in hypothalamic neurons in mice that exhibited depression-like behaviors and decreased the degree of neuronal morphological *** vivo and in vitro studies indicated that XYS increased the expression of AdipoR1 in hypothalamic *** Adiponectin may be a key regulator linking depression and metabolic disorders;regulation of the hypothalamic AdipoR1/AMPK/

关键词： Depression Xiaoyao San Chronic social defeat stress Adiponectin Adiponectin receptor 1 Glucose metabolism disorders