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EXPERIMENTAL RESEARCH ON THE SHAPE CHARACTERS OF NATURAL AND VENTILATED SUPERCAVITATION

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Journal of Hydrodynamics 2007年第5期19卷 564-571页

作者： zhang Xue-wei wei ying-jie zhang jia-zhong wang cong yu kai-ping School of Astronautics Harbin Institute of Technology Harbin 150001 China

A series of projectile and water-tunnel experiments were conducted to investigate the shape characters of natural and ventilated supercavitation. It was found that the shape and dimensions of both the natural supercavitation and the ventilated supercavitation are similar through the comparison of them when the cavitation number is small and equal, and the contour of both the natural supercavitation and the ventilated supercavitation can be calculated effectively with the Savchenko formula. The gravity effect can induce the asymmetry of ventilated supercavitation, and the asymmetry is more apparent as the Froude number is smaller. The empirical formula for calculating the axial deformation of ventilated supercavitation was corrected and expanded based on experiment data. The evolution rules of both the natural supercavitation and the ventilated supercavitation were described, and the vortex frequency of natural cavitation was obtained. In addition, the hysteretic aspect was observed between the development and the fall process of ventilated cavitation.

关键词： natural cavitation ventilated cavitation shapecharacters water tunnel experiment projectile experiment

Association between Chinese Medicine Therapy and Survival Outcomes in Postoperative Patients with NSCLC: A Multicenter, Prospective, Cohort Study

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Chinese Journal of Integrative Medicine 2019年第11期25卷 812-819页

作者： wang Xue-qian zhang ying HOU wei wang ying-tian ZHENG jia-bin li jie liN li-zhu jiaNG Yi-lan wang Shen-yu XIE ying zhang Hong-liang SHU Qi-jin li ping wang wei YOU jian-liang li Ge liU jie FAN Hui-ting zhang Mei-ying liN Hong-sheng Department of Oncology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing (100053)China Department of Oncology Wuxi Hospital of Traditional Chinese MedicineWuxiJiangsu Province (214000)China Department of Oncology Dalian Hospital of Traditional Chinese MedicineDalianLiaoning Province (116000)China Department of Oncology The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou (510000)China Department of Oncology Hunan Academy of Traditional Chinese Medicine Affiliated HospitalChangsha (410000)China Department of Integrated TCM & Western Medicine Cancer Hospital of Liaoning ProvinceShenyang (110000)China Department of Traditional Chinese Medicine Cancer Hospital of Shanxi ProvinceTaiyuan (030000)China Department of Oncology The Xinjiang Uygur Autonomous Region Traditional Chinese Medicine HospitalUrumqi (830000)China Department of Oncology Zhejiang Provinee Traditional Chinese Medicine HospitalHangzhou (310000)China Oncology Department of Traditional Chinese Medicine Anhui Provincial HospitalHefei (230000)China Oncology Department of Traditional Chinese Medicine Chongqing Cancer HospitalChongqing (400000)China

Objective:To evaluate the association between Chinese medicine(CM)therapy and disease-free survival(DFS)outcomes in postoperative patients with non-small cell lung cancer(NSCLC).Methods:This multiple-center prospective cohort study was conducted in 13 medical centers in *** with stage I,II,or IDA NSCLC who had undergone radical resection and received conventional postoperative treatment according to the National Comprehensive Cancer Network(NCCN)guidelines were *** recruited patients were divided into a CM treatment group and a control group according to their *** in the CM treatment group received continuous CM therapy for more than 6 months or until disease *** in the control group received CM therapy for less than 1 ***-up was 8nducted over 3 *** primary outcome was DFS,with recurrence/metastasis rates as a secondary ***:Between May 2013 and August 2016,503 patients were enrolled into the cohort;266 were classified in the CM treatment group and 237 in the control *** for covariates,high exposure to CM was associated with better DFS[hazard ratio(HR)=0.417,95%confidential interval(Cl):0.307-0.567)].A longer duration of CM therapy(6-12 months,12-18 months,>24 months)was associated with lower recurrence and metastasis rates(HR=0.225,0.119 and 0.083,respectively).In a subgroup exploratory analysis,CM therapy was also a protective factor of cancer recurrence and metastasis in both stage n-MA(HR=0.50,95%Cl:0.37-0.67)and stage IDA NSCLC postoperative patients(HR=0.48,95%Cl:0.33-0.71),DFS was even longer among CM treatment group ***:Lon ger duration of CM therapy could be 8nsidered a protective factor of cancer recurrence and *** treatment is associated with improving survival outcomes of postoperative NSCLC patients in China.

关键词： Chinese medicine non-small cell lung cancer postoperative care cohort study disease-free survival

The effect of secondary phase on corrosion behaviors of the titanium–zirconium–molybdenum alloy

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Tungsten 2024年第2期6卷 342-354页

作者： Song-wei Ge ping Hu jie Deng Shi-Lei li hai-Rui Xing jia-yu Han Xing-jiang Hua li wang Jun-Zhou Yang Bo Jin Wen zhang Kuai-She wang School of Metallurgy Engineering Xi’an University of Architecture and TechnologyXi’an 710055China National and Local Joint Engineering Research Center for Functional Materials Processing Xi’an University of Architecture and TechnologyXi’an 710055China Western Xinxing Rare and Precious Metals Co. Ltd.Shangluo 726000China Northwest Institute for Non-Ferrous Metal Research Xi’an 710016China

As the range of applications for molybdenum and its alloys has expanded,the corrosive environment for molybdenum alloys has become more *** the past,the content of doping elements has been studied to investigate their infl uence on the corrosion performance of titanium–zirconium–molybdenum(TZM)*** this paper,it is considered that the second phase in the alloy is the main factor aff ecting the corrosion performance of TZM *** comparing the corrosion behavior of molybdenum metal and TZM alloy,the eff ect of the secondary phase on corrosion behaviors of TZM alloy has been *** results show that the second phase reduces the corrosion resistance of the TZM *** potential of the second phase is 73.7 mV higher than that of the Mo matrix,which contributes to the formation of microscopic electric *** the action of microscopic electric couples,pitting corrosion is preferentially formed at the interface between the second phase and the matrix,which accelerates the corrosion of the *** paper provides a theoretical basis for the application of TZM alloys in corrosive environments.

关键词： Secondary phase Electrochemical corrosion Titanium–zirconium–molybdenum(TZM) Galvanic corrosion Corrosion resistance

Wide-field auroral imager onboard the Fengyun satellite

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light(Science & Applications) 2019年第1期8卷 776-787页

作者： Xiao-Xin zhang Bo Chen Fei He Ke-Fei Song ling-ping He Shi-jie liu Quan-Feng Guo jia-wei li Xiao-Dong wang Hong-Ji zhang hai-Feng wang Zhen-wei Han liang Sun Pei-jie zhang Shuang Dai Guang-Xing Ding li-Heng Chen zhong-Su wang Guang-wei Shi Xin zhang Chao yu zhong-Dong Yang Peng zhang Jin-Song wang National Satellite Meteorological Center China Meteorological AdministrationBeijingChina Key Laboratory of Space Weather National Center for Space WeatherChina Meteorological AdministrationBeijingChina Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchunChina State Key Laboratory of Applied Optics Chinese Academy of SciencesChangchunChina Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijingChina Institutions of Earth Science Chinese Academy of SciencesBeijingChina

The newly launched Fengyun-3D(FY-3D)satellite carried a wide-field auroral imager(WAI)that was developed by Changchun Institute of Optics,Fine Mechanics and Physics,Chinese Academy of Sciences(CIOMP),which will provide a large field of view(FOV),high spatial resolution,and broadband ultraviolet images of the aurora and the ionosphere by imaging the N2 LBH bands of *** WAI consists of two identical cameras,each with an FOV of 68°in the along-track direction and 10°in the cross-track *** two cameras are tilted relative to each other to cover a fan-shaped field of size 130°×10°.Each camera consists of an unobstructed four-mirror anastigmatic optical system,a BaF2 filter,and a photon-counting imaging *** spatial resolution of WAI is ~10 km at the nadir point at a reference height of 110 km above the Earth’s *** sensitivity is>0.01 counts s^(−1) Rayleigh^(−1) pixel^(−1)(140-180 nm)for both cameras,which is sufficient for mapping the boundaries and the fine structures of the auroral oval during storms/*** on the tests and calibrations that were conducted prior to launch,the data processing algorithm includes photon signal decoding,geometric distortion correction,photometric correction,flatfield correction,line-of-sight projection and correction,and normalization between the two *** processed images are compared with DMSP SSUSI *** agreement between the images that were captured by two instruments demonstrates that the WAI and the data processing algorithm operate normally and can provide high-quality scientific data for future studies on auroral dynamics.

关键词： storm correction field

Three-dimensional super-resolution longitudinal magnetization spot arrays

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light(Science & Applications) 2017年第1期6卷 630-637页

作者： zhong-Quan Nie Han lin Xiao-Fei liu Ai-ping Zhai Yan-Ting Tian Wen-jie wang Dong-yu li wei-Qiang Ding Xue-Ru zhang ying-lin Song Bao-Hua jia Key Lab of Advanced Transducers and Intelligent Control Systems Ministry of Education of Shanxi ProvinceCollege of Physics and OptoelectronicsTaiyuan University of TechnologyTaiyuan 030024China Centre for Micro-Photonics Faculty of ScienceEngineering and TechnologySwinburne University of TechnologyHawthornVictoria 3122Australia Department of Science Taiyuan Institute of TechnologyTaiyuan 030008China Department of Physics Lingnan Normal UniversityZhanjiang 524048China Department of Physics Harbin Institute of TechnologyHarbin 150001China

We demonstrate an all-optical strategy for realizing spherical three-dimensional(3D)super-resolution(∼λ3/22)spot arrays of pure longitudinal magnetization by exploiting a 4πoptical microscopic setup with two high numerical aperture(NA)objective lenses,which focus and interfere two modulated vectorial *** phase filters(MPFs)are designed via an analytical approach derived from the vectorial Debye diffraction theory to modulate the two circularly polarized *** system is tailored to constructively interfere the longitudinal magnetization components,while simultaneously destructively interfering the azimuthal *** a result,the magnetization field is not only purely longitudinal but also super-resolved in all three ***,the MPFs can be designed analytically to control the number and locations of the super-resolved magnetization spots to produce both uniform and nonuniform arrays in a 3D ***,an all-optical control of all the properties of light-induced magnetization spot arrays has been demonstrated for the first *** results open up broad applications in magnetic-optical devices such as confocal and multifocal magnetic resonance microscopy,3D ultrahigh-density magneto-optic memory,and light-induced magneto-lithography.

关键词： inverse Faraday effect longitudinal magnetization magnetic-optical devices magneto-optics vectorial beams vectorial Debye diffraction theory

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空化器参数对通气超空泡形态影响的实验研究

工程力学 2007年第3期24卷 159-164页

作者：贾力平王聪于开平魏英杰王海斌张嘉钟哈尔滨工业大学航天学院哈尔滨150001

为了在低速下获取形态可控有效减阻的通气超空泡,利用中速可持续通气空泡水洞开展了空化器参数对通气超空泡形态影响的研究。研究结果表明:空化器直径与通气超空泡的形态密切相关,在相同流场参数条件下,较大直径的空化器易于空化且在较... 详细信息

为了在低速下获取形态可控有效减阻的通气超空泡,利用中速可持续通气空泡水洞开展了空化器参数对通气超空泡形态影响的研究。研究结果表明:空化器直径与通气超空泡的形态密切相关,在相同流场参数条件下,较大直径的空化器易于空化且在较低的通气率下即可形成较大的通气超空泡;通气超空泡的优良率与空化器直径密切相关;不易选取空化器直径与模型后体直径比值Dn/D<0.263的空化器;空化器线形同样也是一个重要的参数,例如,在相同流场参数条件下,平头倒角形空化器比圆锥形空化器形成的超空泡尺寸大,对于圆锥形空化器,锥角越小越不易产生通气超空泡。此外,还将圆盘形空化器超空泡形态的试验结果与理论结果进行了比较,其总的规律是相一致的。

关键词：空化器直径空化器线形通气超空泡通气流量水洞实验

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轴对称航行体通气超空泡的特性实验研究

工程力学 2007年第2期24卷 166-171页

作者：王海斌王聪魏英杰于开平张嘉钟贾力平哈尔滨工业大学航天学院哈尔滨150001

为了研究超空泡的减阻效果,保证在较低流速下生成超空泡,在水洞中开展了水下航行体通气超空泡的实验研究。采用通气的方法在较低水速下(V=7m/s～15m/s)生成人工通气超空泡,通过改变通气率和弗洛德数,获得了不同条件下通气空泡的长度,给... 详细信息

为了研究超空泡的减阻效果,保证在较低流速下生成超空泡,在水洞中开展了水下航行体通气超空泡的实验研究。采用通气的方法在较低水速下(V=7m/s～15m/s)生成人工通气超空泡,通过改变通气率和弗洛德数,获得了不同条件下通气空泡的长度,给出了不同空泡长度下的模型阻力系数。研究结果表明,来流速度不变时,空泡长度随通气率的增加而增加,阻力系数随空泡长度的增加先递增后递减;重力场造成了空泡形态的严重不对称,通过比较模型上下表面的空泡长度,定量的给出了弗洛德数对通气空泡长度的影响。当Fr>43.74时,重力场对通气空泡长度的影响几乎可以忽略。

关键词：水下航行体弗洛德数通气超空泡阻力系数水洞实验

Clinical Course and Outcome Patterns of Acute-on-chronic liver Failure:A Multicenter Retrospective Cohort Study

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Journal of Clinical and Translational Hepatology 2021年第5期9卷 626-634页

作者： Man-Man Xu Ming Kong Peng-Fei yu ying-ying Cao Fang liu bing Zhu Yi-Zhi zhang wang Lu Huai-bin Zou bin-wei Duan Shao-li You Shao-jie Xin Tao Han zhong-ping Duan yu Chen Fourth Department of liver Disease(Difficult&Complicated liver Diseases and Artificial liver Center) Beijing You’an Hospital Affiliated to Capital Medical UniversityBeijingChina Beijing Municipal Key Laboratory of liver Failure and Artificial liver Treatment Research BeijingChina Department of Hepatology The Third Central Clinical College of Tianjin Medical UniversityTianjinChina liver Failure Treatment and Research Center The Fifth Medical Center of Chinese PLA General HospitalBeijingChina Department of General Surgery Beijing You’an Hospital Affiliated to Capital Medical UniversityBeijingChina

Background and Aims:Acute-on-chronic liver failure(ACLF)is acute decompensation of liver function in the setting of chronic liver disease,and characterized by high short-term *** this study,we sought to investigate the clinical course of patients at specific time points,and to propose dynamic prognostic ***:We assessed the clinical course of 453 patients with ACLF during a 12-week follow-up period in this retrospective multicenter *** clinical course of patients was defined as disease recovery,improvement,worsening or steady patterns based on the variation tendency in prothrombin activity(PTA)and total bilirubin(TB)at different time ***:Resolution of PTA was observed in 231 patients(51%)at 12 weeks after the diagnosis of *** the remaining patients,66(14.6%)showed improvement and 156(34.4%)showed a steady or worsening *** patients with resolved PTA,the clinical course of TB exhibited resolved pattern in 95.2%,improved in 3.9%,and steady or worse in 0.8%.Correspondingly,in patients with improved PTA,these values for TB were 28.8%,27.3%,and 43.9%,*** patients with steady or worsening PTA,these values for TB were 5.7%,32.3%,and 65.6%,*** prognostic criteria were developed by combining the clinical course of PTA/TB and the clinical outcomes at 4 and 12 weeks after diagnosis in ACLF ***:We propose the following dynamic prognostic criteria:rapid progression,slow progression,rapid recovery,slow recovery,and slow persistence,which lay the foundation for precise prediction of prognosis and the improvement of ACLF therapy.

关键词： Acute-on-chronic liver failure Clinical course Outcome patterns Retrospective cohort study

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

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Signal Transduction and Targeted Therapy 2023年第12期8卷 5919-5930页

作者： lin wang jia-Bao Cao bin-bin Xia yue-Juan li Xuan zhang Guo-Xin Mo Rui-Juan wang Si-Qi Guo yu-Qing zhang Kun Xiao Guang-Fa Zhu Peng-Fei liu li-Cheng Song Xi-Hui Ma ping-Chao Xiang jiang wang yu-Hong liu Fei Xie Xu-Dong zhang Xiang-Xin li Wan-Lu Sun Yan Cao kai-Fei wang Wen-Hui zhang wei-Chao Zhao Peng Yan Ji-Chao Chen yu-wei Yang zhong-Kuo yu Jing-Si Tang li Xiao jie-Min Zhou li-Xin Xie Jun wang College of Pulmonary&Critical Care Medicine 8th Medical Center of Chinese PLA General HospitalBeijing 100091China CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Faculty of Biological Science and Technology Baotou Teacher’s CollegeBaotou 014030China Department of Respiratory Medicine PLA Strategic Support Force Medical CenterBeijing 100101China Department of Respiratory and Critical Care Medicine Beijing Anzhen HospitalCapital Medical UniversityBeijing Institute of HeartLung and Blood Vessel DiseasesBeijing 100029China Respiratory Research Institute Department of Pulmonary&Critical Care MedicineBeijing Key Laboratory of OTIRthe 8th Medical Center of Chinese PLA General HospitalBeijing 100091China Shougang hospital of Peking University Beijing 100144China Department of Respiratory Medicine Beijing Changping HospitalBeijing 102200China Department of Respiratory and Critical Care Medicine Beijing Institute of Respiratory Medicine and Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China Pulmonary research institute Senior Department of Respiratory and Critical Care Medicinethe 8th medical center of Chinese PLA general hospitalBeijing 100091China College of Pulmonary&Critical Care Medicine Chinese PLA General HospitalBeijing 100853China China Aerospace Science&Industry Corporation 731 hospital Beijing 100074China Department of Respiratory and Critical Care Medicine Aerospace Center HospitalBeijing 100049China Vision Medicals Center for Infectious Diseases Guangzhou 510700China

The Omicron variant of the severe acute respiratory syndrome coronavirus 2(SARS‑CoV‑2)infected a substantial proportion of Chinese population,and understanding the factors underlying the severity of the disease and fatality is valuable for future prevention and clinical *** recruited 64 patients with invasive ventilation for COVID-19 and performed metatranscriptomic sequencing to profile host transcriptomic profiles,plus viral,bacterial,and fungal content,as well as virulence factors and examined their relationships to 28-day mortality were *** addition,the bronchoalveolar lavage fluid(BALF)samples from invasive ventilated hospital/community-acquired pneumonia patients(HAP/CAP)sampled in 2019 were included for *** analysis revealed that all Omicron strains belong to BA.5 and BF.7 sub-lineages,with no difference in 28-day mortality between *** to HAP/CAP cohort,invasive ventilated COVID-19 patients have distinct host transcriptomic and microbial signatures in the lower respiratory tract;and in the COVID-19 non-survivors,we found significantly lower gene expressions in pathways related viral processes and positive regulation of protein localization to plasma membrane,higher abundance of opportunistic pathogens including bacterial Alloprevotella,Caulobacter,Escherichia-Shigella,Ralstonia and fungal Aspergillus sydowii and Penicillium *** analysis further revealed significant associations between host immune responses and microbial compositions,besides synergy within viral,bacterial,and fungal *** study presents the relationships of lower respiratory tract microbiome and transcriptome in invasive ventilated COVID-19 patients,providing the basis for future clinical treatment and reduction of fatality.

关键词： patients mortality prevention