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Corrosion behavior of steel rebar in coal gangue-based mortars

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第5期11卷 382-388页

作者： ji-xiu zhang Heng-hu SUN Yin-ming SUN Na zhang Department of Materials Science and Engineering Tsinghua University Beijing 100084 China

Corrosion of steel rebar is the most important durability problem of reinforced concrete. The aim of this research was to investigate the corrosion behavior of steel rebar in simulated pore solutions and gangue-blended cement mortar. The simulated pore solutions were based on the pore solution composition of gangue-blended cement. The pH and Cl-concentration of simulated pore solutions had significant effects on corrosion potential. However,an increase in pH reduced the influence of Cl-concentra-tion on corrosion potential. The corrosion behavior of steel rebar in gangue-blended cement is different from that in simulated solutions. The gangue cementitious mortar surrounding steel rebar provides stable passivity environments for steel,leading to a decrease in ion diffusion coefficients. Alternating current impedance (ACI) analysis results indicated that the indicator Rc for concrete resistivity is higher for gangue mortar than for ordinary Portland cement (OPC),which improves its corrosion potential. The results from energy dispersive X-ray analysis (EDX) showed more aluminates and silicates at the rebar interface for gangue-blended cement. These aluminates improve the chloride binding capacity of hydrates in mortar,and increase the corrosion protection of steel rebar.

关键词： Steel rebar Corrosion Coal gangue Electrochemical

Progression and Regression of Abdominal Aortic Aneurysms in Mice

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Current Medical Science 2021年第5期41卷 901-908页

作者： Yu-chao DING Xian-jing zhang ji-xiu zhang Zi-yi ZHAI Mei-xia zhang Bao-hong jiANG Shanghai Institute of Materia Medica Chinese Academy of SciencesShanghai 201203China The College of Basic Medical Science China Medical UniversityShenyang 110122China

Objective:Abdominal aortic aneurysm(AAA)is a significant medical problem with a high mortality ***,the underlying mechanism for the progression and regression of AAA is ***:Experimental model of AAA was first created by porcine pancreatic elastase incubation around the infrarenal aorta of C57BL/6 ***,AAA progression and regression were evaluated based on the diameter and volume of *** aortas were harvested for hematoxylin-eosin staining(HE),orcein staining,sirius red staining,immunofluorescence analysis and peris’prussian blue staining at the indicated time ***,P-aminopropionitrile monofumarate(BAPN)was used to explore the underlying mechanism of the regression of ***:When we extended the observation period to 100 days,we not only observed an increase in the AAA diameter and volume in the early stage,but also a decrease in the late *** with AAA diameter and volume,the aortic thickness showed the same tendency based on HE *** elastin and collagen content first degraded and then regenerated,which corresponds to the early deterioration and late regression of ***,endogenous up-regulation of lysyl oxidase(LOX)was detected,accompanying the regression of AAA,as detected by an immunofluorescent *** and LOX inhibitor considerably inhibited the regression of AAA,paralleling the degradation of elastin lamella and ***:Taken together,we tentatively conclude that endogenous re-generation of LOX played an influential role in the regression of ***,regulatory factors on the generation of LOX exhibit promising therapeutic potential against AAA.

关键词： abdominal aortic aneurysm disease progression disease regression elastogenesis lysyl oxidase

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： xiu-Yun Zhao De-En Xu Ming-Lei Wu ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

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Nano-Micro Letters 2025年第2期17卷 401-416页

作者： Chen Li Leilei Liang Baoshan zhang Yi Yang Guangbin ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

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文明叙事:习近平文化思想的方法论审视

新疆师范大学学报（哲学社会科学版） 2025年第1期46卷 34-42页

作者：张明谷生秀南京大学马克思主义学院江苏南京210023

文明是中国共产党百余年推进马克思主义中国化时代化的核心线索,文明叙事是中国共产党历史叙事的重要维度,也是习近平文化思想的重要方法论。习近平文化思想的深厚文明意蕴体现在四个方面:一是从历史纵深出发把握“走自己的路”的文明基... 详细信息

文明是中国共产党百余年推进马克思主义中国化时代化的核心线索,文明叙事是中国共产党历史叙事的重要维度,也是习近平文化思想的重要方法论。习近平文化思想的深厚文明意蕴体现在四个方面:一是从历史纵深出发把握“走自己的路”的文明基因,即从中华5000多年文明的历史传承中把握中国道路的来龙去脉及其内在逻辑必然;二是以“第二个结合”为根本方法,重塑发展中华文明的使命担当,不断推动建设中华民族现代文明实现传统文明的现代新生;三是坚守文明超越理念,将新文明的建构与中国式现代化的现实实践相互关联,以中国式现代化创造人类文明新形态,打破西方以资本逻辑为核心的形而上学抽象文明观的历史困境;四是坚持文明交流互鉴,推动落实全球文明倡议,构建人类文明交往新范式。

关键词：习近平文化思想文明叙事 “走自己的路” “第二个结合” 文明交流互鉴

Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao jianjian Chu Tinglin zhang Tong Yin Yuankai Gu Wendanqi Liang Wenbo ji jianhua Zhuang Yan Liu jie Gao You Yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao zhang Li jia xiu-Jun Zhan Charity Ngina Qing-Rui zhang Xiao-Ge Li Qi-Bao jiang Shi Bai Miao-Miao jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-jie Quan Hao Liang Yong-Hong Tang Li jiang Xiong-Ying ji Feng-Ying zhang Ping zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

In situ observation and modeling of austenite grain growth in a Nb-Ti-bearing high carbon steel

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Journal of Iron and Steel Research International 2019年第3期26卷 292-300页

作者： Guang ji xiu-hua Gao Zhen-guang Liu Ke zhang State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina jiangsu Shagang Group Huaigang Special Steel Co. Ltd.Huaian 223002JiangsuChina School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003JiangsuChina Institute of Research of Iron and Steel ShasteelZhangjiagang 215625JiangsuChina

In situ measurements of austenite grain growth were made at various temperatures in the range of 1273-1473 K with subsequent isothermal holding time of 3600 s for the Nb-Ti-bearing and Nb-Ti-free high carb on steel by using a confocal laser scanning *** solid solute behavior of Nb-Ti carbides during austenitizing process was *** experimental results indicate that the austenite grains of both steels grow up gradually with increasing the heating temperature and holding time;the size and growth rate of austenite grain of Nb-Ti-bearing high carbon steel are much lower than those of Nb-Ti-free high carbon steel.A large amount of(Nb,Ti)(C,N)nanoparticles are observed in Nb-Tibearing steel,which retain the strong pinning effect on austenite grain *** kinetics model of austenite grain growth of Nb-Ti-bearing steel during isothermal heat treatment is obtained and the predicted values calculated by using the model meet the experimental values very well.

关键词： Con focal laser scanning microscope Nb-Ti microalloying High carb on steel Grain growth Nanoparticle Grain growth model