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functional hair follicle regeneration:an updated review

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Signal Transduction and Targeted Therapy 2021年第3期6卷 723-733页

作者： Shuaifei ji Ziying Zhu Xiaoyan Sun Xiaobing fu Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Department and 4th Medical Center PLA General Hospital and PLA Medical CollegePLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin InjuryRepair and RegenerationResearch Unit of Trauma CareTissue Repair and RegenerationChinese Academy of Medical Sciences2019RU051Beijing 100048People's Republic of China

The hair follicle(HF)is a highly conserved sensory organ associated with the immune response against pathogens,thermoregulation,sebum production,angiogenesis,neurogenesis and wound *** recent advances in lineage-tracing techniques and the ability to profile gene expression in small populations of cells have increased the understanding of how stem cells operate during hair growth and regeneration,the construction of functional follicles with cycling activity is still a great challenge for the hair research field and for translational and clinical *** that hair formation and cycling rely on tightly coordinated epithelial-mesenchymal interactions,we thus review potential cell sources with HF-inducive capacities and summarize current bioengineering strategies for HF regeneration with functional restoration.

关键词： healing wound hair

Layout Design of Conductive Heat Channel by Emulating Natural Branch Systems

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Journal of Bionic Engineering 2018年第3期15卷 567-578页

作者： Yidong ji Xiaohong Ding Hao Li min Xiong School of Mechanical engineering University of Shanghai for Science and Technology Shanghai 200093 China

To design effective and easy-to-manufacture conductive heat channels, a heuristic method by emulating the natural branch systems is suggested. The design process of the method is divided into two steps, which are the principal channel design and the lateral channel design. During the process, the width of each channel is controlled by the bifurcation law, and the end point of the channel is located at the point with the maximum temperature while the start points of the principal channel and the lateral channel are respectively determined by the location of the heat sink and the law of the minimum thermal resistance. Four design examples with different boundary conditions are studied by the suggested method, and the design results are compared with that of the traditional structural topology optimization method. Not only lower maximum temperature and relatively uniform distribution of temperature are obtained by the suggested method, but also straight channels are achieved without gray element, which is easy to manufacture. The suggested method inspired by the natural branch systems can provide an effective solution for heat channel design in the heat dissipation structures.

关键词： conductive heat channel bionic layout design natural branch system thermal resistance bifurcation law

Non-Markovian Effect on the Classical and Quantum Correlations

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Chinese Physics Letters 2011年第6期28卷 44-47页

作者： XU Guo-fu TONG Dian-min Department of Physics Shandong UniversityJinan 250100

We evaluate the dynamics of quantum and classical correlations in the presence of non-Markovian *** considering an entangled pair of spins in the noise environment described by Ornstein–Uhlenbeck processes,we show that the quantum discord of some states is completely unaffected by independent Ornstein–Uhlenbeck noises for long intervals of time,and that the inevitable onset of the sudden decrease of the quantum discord can be substantially delayed by the decrease of the noise bandwidthγ,whereγ^(−1)=τc defines the environment's finite correlation time of the noise.

关键词： quantum Markovian finite

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Line Graph Links

Acta Mathematicae Applicatae Sinica 2021年第4期37卷 706-716页

作者： Wei-ling YANG Xian-an jiN fu-ji ZHANG School of Mathematical Sciences Xiamen UniversityXiamen361005China

It is well known that a shaded link diagram corresponds to a signed plane *** graph theory,line graph is an old and important concept originally introduced by *** in *** this paper we define the line graph link to be a link which has a diagram whose corresponding signed plane graph is a signed line *** main purpose of the paper is to illustrate the structure of planar line graphs,which permits us to deal with its signed Tutte polynomial and the Jones polynomials of line graph links.

关键词： line graphs planarity structure signed Tutte polynomial

Effect of Micro-Dimples on Hydrodynamic Lubrication of Textured Sinusoidal Roughness Surfaces

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Chinese Journal of Mechanical Engineering 2018年第4期31卷 160-167页

作者： jing-Hu ji Cai-Wei Guan Yong-Hong fu School of Mechanical Engineering Jiangsu University

Surface texturing has been applied to improving the tribological performance of mechanical components for many years. Currently, the researches simulate the film pressure distribution of textured rough surfaces on the basis of the average flow model, and however the influence of roughness on the film pressure distribution could not be precisely expressed. Therefore, in order to study the hydrodynamic lubrication of the rough textured surfaces, sinusoidal waves are employed to characterize untextured surfaces. A deterministic model for hydrodynamic lubrication of microdimple textured rough surfaces is developed to predict the distribution of hydrodynamic pressure. By supplementing with the JFO cavitation boundary, the load carrying capacity of the film produced by micro-dimples and roughness is obtained. And the geometric parameters of textured rough surface are optimized to obtain the maximum hydrodynamic lubrication by specifying an optimization goal of the load carrying capacity. The effect of roughness on the hydrodynamic pressure of surface texture is significant and the load carrying capacity decreases with the increase of the roughness ratio because the roughness greatly suppresses the hydrodynamic effect of dimples. It shows that the roughness ratio of surface may be as small as possible to suppress the effect of hydrodynamic lubrication. Additionally,there are the optimum values of the micro-dimple depth and area density to maximize the load carrying capacity for any given value of the roughness ratio. The proposed approach is capable of accurately reflects the influence of roughness on the hydrodynamic pressure, and developed a deterministic model to investigate the hydrodynamic lubrication of textured surfaces.

关键词： Hydrodynamic lubrication Surface texturing Micro-dimple Roughness surface Sinusoidal wave

FEM Analysis of Spring-backs in Age Forming of Aluminum Alloy Plates

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Chinese Journal of Aeronautics 2007年第6期20卷 564-569页

作者： Huang Lin Wan min Chi Cailou ji Xiusheng Department of Aircraft Manufacturing Engineering Beijing University of Aeronautics and Astronautics Beijing 100083 China Technology Research Institute Shenyang Aircraft Corporation Shenyang 100034 China

The age forming technology, characterized by huge spring-backs, has been developed to manufacture large integral wing-skin panel parts, which necessitates devising a method of predicting spring-backs. A 7B04-T7451 aluminum alloy creep test in tension is accomplished at 155 ℃, and the creep curves are obtained. The material constants of the mechanism-based creep constitutive equations are determined through experiments. The age forming process and the spring-backs of 7B04 aluminum alloy plates are analyzed using the commercial finite element software ABAQUS. The effects of plate thickness and forming time on spring-backs are researched. The spring-backs decrease with the increase of plate thickness and forming time. The test results verify the reliability of the finite element method （FEM） analysis.

关键词： aluminum alloy age forming constitutive equation FEM spring-back

Effects of Defocus Distance on Three-Beam Laser Internal Coaxial Wire Cladding

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Chinese Journal of Mechanical Engineering 2021年第4期34卷 56-77页

作者： Shaoshan ji Fan Liu Tuo Shi Geyan fu Shihong Shi School of Mechanical and Electrical Engineering Soochow UniversitySuzhou 215000China School of Optoelectronic Science and Engineering Soochow UniversitySuzhou 215000China.

Three-beam laser internal coaxial wire feeding cladding is regarded as a promising additive manufacturing technique because it is highly efficient and *** this study,the effects of the defocus distance on cladding using a three-beam laser with internal wire feeding are experimentally and numerically studied.A process map indicating the surface characteristics at different defocus distances with various parameter combinations was *** transmission characteristics including laser intensity,beam size,and laser spot distance of the three-beam laser at different defocus distances were analyzed using TracePro *** on the TracePro results as heat source,a three-dimensional transient finite element(FE)thermal model was formulated to predict the thermal field,temperature history and molten pool shape at different defocus distances.A molten pool with a flat bottom and low melting depth is generated when the defocus distance is−2.5 mm,whereas when this distance is−1.5 mm,a pool with a valley-shaped bond and high melting depth is *** simulated results of the temperature cycle and clad geometry are both validated and found to well agree with experimental *** influence of the defocus distance on the microstructure and microhardness are discussed based on the temperature history and cooling *** the increase in the absolute defocus distance,the height and dilution of the clad decreased,whereas the width *** addition,the effects of defocus distance with various parameter combinations on clad geometry were explored using the formulated FE model.

关键词： Three beams laser Wire cladding Finite element analysis Defocus distance

Estimation of plasma density perturbation from dusty plasma injection by laser irradiation on tungsten target in DiPS

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Plasma Science and Technology 2020年第4期22卷 90-96页

作者： In Je KANG min-Keun BAE In Sun PARK min ji LEE Kyu-Sun CHUNG Department of Electrical Engineering Hanyang UniversitySeoul 133791Republic of Korea Plasma Technology Research Center National Fusion Research InstituteGunsan 54004Republic of Korea

To investigate the interaction of dusty plasma with magnetized plasmas at divertor plasma simulator,radial profiles of plasma density(ne)and electron temperature were measured in terms of plasma discharge currents and magnetic flux intensity by using a fast scanning probes system with triple *** plasma with dusts(a generation rate of 3μg s-1 and a size of 1–10μm)was produced via interactions between a high-power laser beam and a full tungsten *** ne increases,the scale of the effects of dusty plasma injection on magnetized plasmas was ***,the duration of transient fluctuation was *** numerical estimation of plasma density perturbation due to dusty plasma injection,the result was 10%at a core region of the magnetized plasma with ne of(2–5)×10^11 cm^-3 at steady state condition.

关键词： plasma density perturbation dusty plasma tungsten dust DiPS

Liquid metal welding enabling high loading binder/carbon-free layered oxide cathode toward high-performance liquid and solid-state battery

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Rare Metals 2023年第5期42卷 1583-1593页

作者： Xiang Han Lan-Hui Gu min Xu min-Feng Chen ji-Zhang Chen College of Materials Science and Engineering Co-Innovation Center of Efficient Processing and Utilization of Forest ResourcesNanjing Forestry UniversityNanjing210037China

High loading cathode with high active material proportion is a practical demand but far below the desirable value to achieve high energy density lithium-ion batteries(LIBs).Normally,the Li^(+)/electron transport between active materials and electrolyte/c arbon,however,it is poor and areal resistance is extremely high for a high loading/thick *** this manuscript,taking high-voltage lithium cobalt oxide LiCoO_(2)(LCO)as an example,we design a facile liquid metal welding method enabled by a low melting-point indium-tin oxide In_(2)O_(3)/SnO_(2)(ITO)during a thermal treatment process,the strongly adhesion active particles show robust mechanical property for the free-standing LCO cathode with a pellet *** also demonstrate that the O_(2)atmosphere plays a critical role on the interfacial property,that is preventing the layered structure to rock-salt Co_(3)O_(4)as well as further enhancing the interfacial mechanical *** expected,the LCO-ITO free-standing cathode not only shows robust mechanical property with densely packed configuration but also provides a fast Li^(+)/electron pathway at the ***,the LCO-ITO composite cathode exhibits excellent electrochemical cycling performance in both liquid and solid-state *** example,even at a high active material mass of 56 mg·cm^(-2),the LCO cathode still delivers a specific capacity of 151 mAh·g^(-1)and maintains132.5 mAh·g^(-1)(corresponding to 7.4 mAh·cm^(-2))after *** LCO-ITO-O_(2)cathode is also applicable to a solidstate cell,which exhibits a high capacity of 100.4 mAh·g^(-1)after 200 cycles of long-term *** excellent electrochemical of the LCO-ITO-O_(2)reveals the successful engineering mechanical architecture and interfacial carriers transport,which may be expected as an alternative approach to achieve high energy density LIBs.

关键词： Lithium-ion battery(LIB) High loading cathode Liquid metal welding Mechanical property Interfacial carriers transport