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基于NFC的主动配电网与微网协同经济调度系统设计

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通信电源技术 2024年第15期41卷 119-121页

作者：罗通季晓力国电南瑞南京控制系统有限公司江苏南京211106

为应对主动配电网和微电网带来的挑战,文章提出一种基于近场通信(Near Field Communication,NFC)的协同经济调度系统。该系统采用分层架构,包括用户层、调度层、通信层以及设备层,实现用户友好的人机交互、高效的资源优化调度以及可靠... 详细信息

为应对主动配电网和微电网带来的挑战,文章提出一种基于近场通信(Near Field Communication,NFC)的协同经济调度系统。该系统采用分层架构,包括用户层、调度层、通信层以及设备层,实现用户友好的人机交互、高效的资源优化调度以及可靠的数据传输。实验结果表明,该系统能够显著提高负荷满足率、可再生能源消纳率、储能利用率以及通信成功率。

关键词：主动配电网微网协同经济调度

基于TLR4/MyD88/NF-κB信号通路探讨刺芒柄花素对LPS诱导的大鼠子宫内膜上皮细胞损伤的影响

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中药药理与临床 2024年第2期40卷 62-67页

作者：季晓黎杨成成黄利张永青宋晓庆成都中医药大学附属医院成都610072

目的:探讨刺芒柄花素通过调控Toll样受体4(TLR4)/髓样分化因子88(MyD88)/核转录因子κB(NF-κB)信号通路对脂多糖(LPS)诱导的大鼠子宫内膜上皮细胞损伤的影响。方法:以LPS诱导大鼠子宫内膜上皮细胞损伤,采用CCK8法检测细胞活性;采用RT-q... 详细信息

目的:探讨刺芒柄花素通过调控Toll样受体4(TLR4)/髓样分化因子88(MyD88)/核转录因子κB(NF-κB)信号通路对脂多糖(LPS)诱导的大鼠子宫内膜上皮细胞损伤的影响。方法:以LPS诱导大鼠子宫内膜上皮细胞损伤,采用CCK8法检测细胞活性;采用RT-qPCR法检测TLR4过表达效率;流式细胞术检测细胞凋亡;ELISA法检测肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)和IL-6含量;Western Blot法检测TLR4/MyD88/NF-κB通路相关蛋白的表达。结果:与空白对照组比较,模型对照组细胞抑制率、细胞凋亡率、炎症因子TNF-α、IL-1β和IL-6的含量明显增加,p-P65/P65、p-IκBα/IκBα、MyD88和TLR4蛋白表达明显上调(P<0.05或P<0.01);与模型对照组相比,刺芒柄花素12μmol/L组细胞抑制率、细胞凋亡率、炎症因子TNF-α、IL-1β和IL-6的含量明显降低,p-P65/P65、p-IκBα/IκBα、MyD88和TLR4蛋白表达明显下调(P<0.05或P<0.01);TLR4过表达对刺芒柄花素作用的影响结果显示,与刺芒柄花素+Ov-NC组相比,刺芒柄花素+Ov-TLR4组细胞抑制率、细胞凋亡率、炎症因子TNF-α、IL-1β和IL-6含量明显增加,p-P65/P65、p-IκBα/IκBα、MyD88和TLR4蛋白表达明显上调(P<0.05或P<0.01)。结论:刺芒柄花素能够抑制TLR4的表达,从而抑制TLR4/MyD88/NF-κB信号通路的激活,以减轻LPS诱导的大鼠子宫内膜上皮细胞凋亡及炎症损伤。

关键词：刺芒柄花素子宫内膜上皮细胞脂多糖 Toll样受体4/髓样分化因子88/核转录因子κB信号通路

酶联免疫法和金标法对HIV抗体的检测结果比较

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临床医学工程 2024年第3期31卷 337-338页

作者：季晓丽卢莹莹赵小瑞南阳市卧龙区疾病预防控制中心卫生检验检测中心河南南阳473000 南阳市卧龙区妇幼保健院检验科河南南阳473000

目的探讨酶联免疫法和金标法对HIV抗体的检测结果,明确针对艾滋病更为有效的临床筛查手段。方法选取264例疑似艾滋病患者,采集入组患者静脉血并进行酶联免疫法与金标法检测HIV抗体。以临床诊断结果为准,比较酶联免疫法和金标法与临床... 详细信息

目的探讨酶联免疫法和金标法对HIV抗体的检测结果,明确针对艾滋病更为有效的临床筛查手段。方法选取264例疑似艾滋病患者,采集入组患者静脉血并进行酶联免疫法与金标法检测HIV抗体。以临床诊断结果为准,比较酶联免疫法和金标法与临床检查结果的一致性;比较酶联免疫法和金标法对艾滋病的诊断效能。结果 264例疑似艾滋病患者中,经临床筛查试验和确证试验确诊225例。κ检验分析结果显示,酶联免疫法检查结果与临床诊断结果具有高度一致性(κ=0.897, P 0.05)。结论酶联免疫法和金标法对HIV抗体均具有较好的检出效果,可为艾滋病临床诊断提供较为准确的数据参考,临床检测中可根据患者自身情况选择相应的检测方法,必要时还可进行联合检测。

关键词：酶联免疫法金标法艾滋病 HIV抗体

陕西佛坪国家级自然保护区生态环境保护成效评估

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绿色科技 2024年第10期26卷 186-191页

作者：陈原玉冀晓丽曹庆朱琳王兰宁杨丽陕西佛坪国家级自然保护区管理局陕西佛坪723400

2023年陕西佛坪国家级自然保护区(以下简称佛坪保护区)采用量化分析评估方式,对生物多样性保护和生态系统服务功能的综合成效进行评估。本次评估能够科学直观地反映佛坪保护区的保护成效,并促进生态环境质量持续改善和升级。结果表明:... 详细信息

2023年陕西佛坪国家级自然保护区(以下简称佛坪保护区)采用量化分析评估方式,对生物多样性保护和生态系统服务功能的综合成效进行评估。本次评估能够科学直观地反映佛坪保护区的保护成效,并促进生态环境质量持续改善和升级。结果表明:生态环境变化评分(E_(C))为69.38,评估等级变好(65≤E_(C)<85);生态环境状况评分(E_(S))为96.75,等级为I级(E_(S)≥85),总体判定为优。基于评估结果,提出了运用先进技术、加大人才培养等对策。以期为自然保护区生态环境保护成效评估提供现实案例,并为今后同类型自然保护区生态环境保护提供参考。

关键词：佛坪国家级自然保护区生物多样性生态系统服务生态环境保护成效

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基于“血不利则为水”从湿瘀论治子宫腺肌病

成都中医药大学学报 2024年第2期47卷 55-58页

作者：李若楠杨成成黄利李茂雅李斌文怡季晓黎成都中医药大学附属医院四川成都610072

“血不利则为水”出自《金匮要略》,是张仲景提出的一种关于血水之间病理关系的论述。瘀血阻滞是子宫腺肌病的核心病机,湿瘀互结型是其较为多见的临床证型。本文通过探讨血水之间互化互病的关系,以“血不利则为水”为切入点论治湿瘀互... 详细信息

“血不利则为水”出自《金匮要略》,是张仲景提出的一种关于血水之间病理关系的论述。瘀血阻滞是子宫腺肌病的核心病机,湿瘀互结型是其较为多见的临床证型。本文通过探讨血水之间互化互病的关系,以“血不利则为水”为切入点论治湿瘀互结型子宫腺肌病,提出瘀血是子宫腺肌病发病之源,瘀血阻滞进而引发津液运行代谢失常产生病理水湿,水湿停滞又加重瘀血的阻滞,瘀血与水湿互为因果、相互胶结而发病,故治疗应调治津血,可选择祛瘀与除湿并行的血水同治法,为子宫腺肌病的临床治疗提供理论依据。

关键词：血不利则为水子宫腺肌病瘀血水湿血水同治当归芍药散

顺阿曲库铵用于输尿管镜下激光碎石术患者喉罩置入的剂量研究

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国际泌尿系统杂志 2024年第1期44卷 69-73页

作者：薛原吴晓晨吉晓丽王梅许志斌郭毛毛李小静姜琳泰州市人民医院麻醉科泰州225300 兖矿新里程总医院内科邹城273500 泰州市人民医院泌尿科泰州225300

目的探讨顺阿曲库铵用于输尿管镜下激光碎石术患者喉罩置入的半数有效剂量(ED50)和95%有效剂量(ED95)。方法选取2020年1月至2021年2月拟于泰州市人民医院行输尿管镜下激光碎石术的50例患者。使用Dixon序贯法调整患者的顺阿曲库铵用药剂... 详细信息

目的探讨顺阿曲库铵用于输尿管镜下激光碎石术患者喉罩置入的半数有效剂量(ED50)和95%有效剂量(ED95)。方法选取2020年1月至2021年2月拟于泰州市人民医院行输尿管镜下激光碎石术的50例患者。使用Dixon序贯法调整患者的顺阿曲库铵用药剂量,药物剂量梯度依次为0.15、0.125、0.1、0.075、0.05、0.025、0.0125 mg/kg。若上一例患者成功置入喉罩,下一例患者顺阿曲库铵剂量下调一个梯度;若上一例患者置入喉罩失败,下一例患者顺阿曲库铵剂量上调一个梯度。依照上述规则,直至纳入50例患者为止。记录各剂量顺阿曲库铵的总人数及喉罩置入成功人数用于计算ED50和ED95。依据ED50和ED95具体值及各剂量样本量情况,将顺阿曲库铵剂量0.05、0.025、0.0125 mg/kg依次设为顺阿曲库铵0.05 mg/kg组(C0.05组,8例)、顺阿曲库铵0.025 mg/kg组(C0.0125组,22例)、顺阿曲库铵0.0125 mg/kg组(C0.0125组,15例)。记录患者注射顺阿曲库铵前(T0)、注射顺阿曲库铵后3 min(T1)、喉罩置入后即刻(T2)的四个成串刺激(TOF),以及T2时点的气道峰压。记录术中喉罩移位及拔除喉罩后咽痛、喉罩染血、声音嘶哑、喉痉挛等不良反应发生情况。结果使用Probit回归计算ED50和ED95,结果显示顺阿曲库铵用于输尿管镜下激光碎石术患者喉罩置入的ED50和ED95分别为0.025 mg/kg(95%CI:0.010~0.030)和0.045 mg/kg(95%CI:0.030~0.060)。C0.0125组T1时点的TOF(T4/T1值)明显高于C0.025组和C0.05组患者,差异有统计学意义(P0.05)。C0.05组的喉罩染血发生率低于C0.025组和C0.0125组,差异无统计学意义(P=0.063)。结论顺阿曲库铵用于输尿管镜下激光碎石术患者喉罩置入的ED50为0.025 mg/kg(95%CI:0.010~0.030)、ED95为0.045mg/kg(95%CI:0.030~0.060)。

关键词：输尿管结石顺阿曲库铵输尿管软镜碎石术喉罩

A drug-loaded flexible substrate improves the performance of conformal cortical electrodes

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Bio-Design and Manufacturing 2024年第4期7卷 399-412页

作者： Rongrong Qin Tian Li Yifu Tan Fanqi Sun Yuhao Zhou Ronghao Lv xiaoli You Bowen ji Peng Li Wei Huang Frontiers Science Center for Flexible Electronics(FSCFE) Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&Engineering(IBME)Northwestern Polytechnical UniversityXi’an 710072China Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China Ministry of Education Key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingbo 315103China

Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous ***,the inevitable wound caused by surgical implantation of electrodes presents bacterial infection and inflammatory reaction risks associated with foreign body ***,inflammation of the wound area can dramatically worsen in response to bacterial *** consequences can not only lead to the failure of cortical electrode implantation but also threaten the lives of ***,we prepared a hydrogel made of bacterial cellulose(BC),a flexible substrate for cortical electrodes,and further loaded antibiotic tetracycline(TC)and the anti-inflammatory drug dexamethasone(DEX)onto *** encapsulated drugs can be released from the BC hydrogel and effectively inhibit the growth of Gram-negative and Gram-positive ***,therapeutic cortical electrodes were developed by integrating the drug-loaded BC hydrogel and nine-channel serpentine arrays;these were used to record electrocorticography(ECoG)signals in a rat *** to the controlled release of TC and DEX from the BC hydrogel substrate,therapeutic cortical electrodes can alleviate or prevent symptoms associated with the bacterial infection and inflammation of brain *** approach facilitates the development of drug delivery electrodes for resolving complications caused by implantable electrodes.

关键词： Antibacterial Anti-inflammatory Drug loading Cortical electrodes Bacterial cellulose hydrogel

Ultrahigh quantum efficiency photodetector and ultrafast reversible surface wettability transition of square In2O3 nanowires

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Nano Research 2017年第8期10卷 2772-2781页

作者： Ming Meng Xinglong Wu xiaoli ji Zhixing Gan Lizhe Liu jiancang Shen Paul K. Chu School of Physics and Telecommunication Engineering Zhoukou Normal University Zhoukou 466001 China Key Laboratory of Modern Acoustics MOE Institute of Acoustics Collaborative Innovation Center of Advanced Microstructures Notional Laboratory of Solid State Microstructures Nanjing University Nonjing 210093 China School of Electronic Science and Engineering Nanjing University Nanjing 210093 China Key Laboratory of Optoelectronic Technology of jiangsu Province School of Physical Science and Technology Nanjing Normal University Nanjing 210023 China Department of Physics and Materials Science City University ofHong Kong Tat Chee Avenue Kowloon Hong Kong China

Due to a large surface-to-volume ratio, the optoelectronic performance of low- dimensional semiconductor nanostructure-based photodetectors depends in principle on chemisorption/photodesorption at the exposed surface, but practical examples that show such an effect are still unavailable. Some theoretical calculations have predicted that the {001} facets of In2O3 can effectively accumulate photogenerated holes under irradiation, providing a model material to examine whether the facet cutting of nanowires （NWs） can boost their optoelectronic performance. Herein, we present the design and construction of a novel nanowire-based photodetector using square In2O3 NWs with four exposed {001} crystal facets. The photodetector delivers excellent optoelectronic performance with excellent repeatability, fast response speed, high spectral responsivity （Rλ）, and high external quantum efficiency （EQE）. The Rλ and EQE values are as high as 4.8 × 10^6 A/W and 1.46 × 10^9%, respectively, which are larger than those of other popular semiconductor photodetectors. In addition, the square In2O3 NWs show hydrophobic wettability as manifested by a contact angle of 118° and a fast photoinduced reversible switching behavior is observed.

关键词： square In2O3 nanowires crystal facet photodetector reversible wettability transition

Progress in Mechanical Modeling of Implantable Flexible Neural Probes

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1205-1231页

作者： xiaoli You Ruiyu Bai Kai Xue Zimo Zhang Minghao Wang Xuanqi Wang jiahao Wang jinku Guo Qiang Shen Honglong Chang Xu Long Bowen ji Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an710072China National Key Laboratory of Unmanned Aerial Vehicle Technology Northwestern Polytechnical UniversityXi’an710072China Ministry of Education Key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an710072China School of Automobile Chang’an UniversityXi’an710018China MOE Engineering Research Center of Smart Microsensors and Microsystems College of Electronics and InformationHangzhou Dianzi UniversityHangzhou310018China School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi’an710129China

Implanted neural probes can detect weak discharges of neurons in the brain by piercing soft brain tissue,thus as important tools for brain science research,as well as diagnosis and treatment of brain ***,the rigid neural probes,such as Utah arrays,Michigan probes,and metal microfilament electrodes,are mechanically unmatched with brain tissue and are prone to rejection and glial scarring after implantation,which leads to a significant degradation in the signal quality with the implantation *** recent years,flexible neural electrodes are rapidly developed with less damage to biological tissues,excellent biocompatibility,and mechanical compliance to alleviate *** them,the mechanical modeling is important for the optimization of the structure and the implantation *** this review,the theoretical calculation of the flexible neural probes is firstly summarized with the processes of buckling,insertion,and relative interaction with soft brain tissue for flexible probes from outside to ***,the corresponding mechanical simulation methods are organized considering multiple impact factors to realize minimally invasive ***,the technical difficulties and future trends of mechanical modeling are discussed for the next-generation flexible neural probes,which is critical to realize low-invasiveness and long-term coexistence in vivo.

关键词： Mechanical modeling flexible neural probes invasive theoretical calculation simulation