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《史记》《汉书》关系新议

海南热带海洋学院学报 2017年第6期24卷 31-36页

作者：潘铭基香港中文大学中国语言及文学系香港999077

司马迁《史记》载录五帝至汉武3000年史事,勒为一书,共52万多字,开纪传体史书之先。班固《汉书》约80万字,记前汉一代史事,其中汉高祖至武帝太初以前,内容多据《史记》。今考《汉书》参考《史记》之篇章多达61篇,因此,《史》《汉》对读... 详细信息

司马迁《史记》载录五帝至汉武3000年史事,勒为一书,共52万多字,开纪传体史书之先。班固《汉书》约80万字,记前汉一代史事,其中汉高祖至武帝太初以前,内容多据《史记》。今考《汉书》参考《史记》之篇章多达61篇,因此,《史》《汉》对读自《汉书》书成以后屡有出现。《史记》成书以后,流传不广,甚至因"微文刺讥"而号为"谤书"。至于《汉书》,极载汉之盛德,传习者众,评价似与《史记》迥异。其实,二书内容相同之处甚多,何以一为"谤书",一为歌功颂德之文?据二书互见之文,可见其中之《春秋》笔法,以及班固《汉书》之史家精神与微言大义。

关键词：史记汉书微言大义

DPHL:A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

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Genomics, Proteomics & Bioinformatics 2020年第2期18卷 104-119页

作者： Tiansheng Zhu Yi Zhu Yue Xuan Huanhuan Gao Xue Cai Sander R.Piersma Thang V.Pham Tim Schelfhorst Richard R.G.D.Haas Irene V.Bijnsdorp Rui Sun Liang Yue Guan Ruan Qiushi Zhang Mo Hu Yue Zhou Winan J.Van Houdt Tessa Y.S.Le Large Jacqueline Cloos Anna Wojtuszkiewicz Danijela Koppers-Lalic Franziska Bottger Chantal Scheepbouwer Ruud H.Brakenhoff Geert J.L.H.van Leenders Jan N.M.Ijzermans John W.M.Martens Renske D.M.Steenbergen Nicole C.Grieken Sathiyamoorthy Selvarajan Sangeeta Mantoo Sze S.Lee Serene J.Y.Yeow Syed M.F.Alkaff Nan Xiang Yaoting Sun Xiao Yi Shaozheng Dai Wei Liu Tian Lu Zhicheng Wu Xiao Liang Man Wang Yingkuan Shao Xi Zheng Kailun Xu Qin Yang Yifan Meng Cong Lu jiang Zhu jin'e Zheng Bo Wang Sai Lou Yibei Dai Chao Xu Chenhuan Yu Huazhong Ying Tony K.Lim jianmin Wu Xiaofei Gao Zhongzhi Luan Xiaodong Teng Peng Wu Shi'ang Huang Zhihua Tao Narayanan G.Iyer Shuigeng Zhou Wenguang Shao Henry Lam Ding Ma jiafu ji Oi L.kon Shu Zheng Ruedi Aebersold Connie R.jimenez Tiannan Guo Zhejiang Provincial Laboratory of Life Sciences and Biomedicine Westlake UniversityHangzhou 310024China Key Laboratory of Structural Biology of Zhejiang Province School of Life SciencesWestlake UniversityHangzhou 310024China Institute of Basic Medical Sciences Westlake Institute for Advanced StudyHangzhou 310024China School of Computer Science Shanghai Key Laboratory of Intelligent Information ProcessingFudan UniversityShanghai 200433China Thermo Fisher Scientific(BREMEN)GmbH Bremen 28195Germany OncoProteomics Laboratory Department of Medical OncologyVU University Medical CenterVU UniversityAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamUrologyCancer Center AmsterdamAmsterdam 1011The Netherlands Thermo Fisher Scientific Shanghai 201206China The Netherlands Cancer Institute Surgical OncologyAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamSurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamPediatric Oncology/HematologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamHematologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamMedical OncologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamNeurosurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamPathologyCancer Center AmsterdamAmsterdam 1011The Netherlands Amsterdam UMC Vrije Universiteit AmsterdamOtolaryngology/Head and Neck SurgeryCancer Center AmsterdamAmsterdam 1011The Netherlands Erasmus MC University Medical Center PathologyRotterdam 1016LVThe Netherlands Erasmus MC University Medical Center SurgeryRotterdam 1016LVThe Netherlands Erasmus MC University Medical Center Medical OncologyRotterdam 1016LVThe Netherlands Department of Anatomical Pathology Singapore General HospitalSingapore 169608Singapore Division of Medical Scie

To address the increasing need for detecting and validating protein biomarkers in clinical specimens,mass spectrometry(MS)-based targeted proteomic techniques,including the selected reaction monitoring(SRM),parallel reaction monitoring(PRM),and massively parallel dataindependent acquisition(DIA),have been *** optimal performance,they require the fragment ion spectra of targeted peptides as prior *** this report,we describe a MS pipeline and spectral resource to support targeted proteomics studies for human tissue *** build the spectral resource,we integrated common open-source MS computational tools to assemble a freely accessible computational workflow based on *** then applied the workflow to generate DPHL,a comprehensive DIA pan-human library,from 1096 data-dependent acquisition(DDA)MS raw files for 16 types of cancer *** extensive spectral resource was then applied to a proteomic study of 17 prostate cancer(PCa)***,PRM validation was applied to a larger study of 57 PCa patients and the differential expression of three proteins in prostate tumor was *** a second application,the DPHL spectral resource was applied to a study consisting of plasma samples from 19 diffuse large B cell lymphoma(DLBCL)patients and 18 healthy control *** expressed proteins between DLBCL patients and healthy control subjects were detected by DIA-MS and confirmed by *** data demonstrate that the DPHL supports DIA and PRM MS pipelines for robust protein biomarker *** is freely accessible at https://***/page/***?id=IPX0001400000.

关键词： Data-independent acquisition Parallel reaction monitoring Spectral library Prostate cancer Diffuse large B cell lymphoma

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魔芋种植对两种梨树林土壤养分的影响

四川林业科技 2015年第1期36卷 48-52页

作者：兰吉萍陈建国内江市林业局四川内江641000 四川省林业科学研究院四川成都610081

林下种植是一种较有发展前景的,具有生态和经济的双重优势的农林复合经济模式。为研究梨树林+魔芋种植模式对林下土壤养分的影响,本试验对内江地区两种梨树(丰水梨和昌吉梨)林下的土壤进行了研究测定。结果表明:种植魔芋显著增加了丰水... 详细信息

林下种植是一种较有发展前景的,具有生态和经济的双重优势的农林复合经济模式。为研究梨树林+魔芋种植模式对林下土壤养分的影响,本试验对内江地区两种梨树(丰水梨和昌吉梨)林下的土壤进行了研究测定。结果表明:种植魔芋显著增加了丰水梨林下土壤全钙(TCa)含量,但对其余土壤养分无显著影响;而种植魔芋显著增加了昌吉梨林下土壤有效磷(AP)和全钾(TK)含量,土壤TCa含量则显著减少。可以看出,梨树林下种植魔芋对土壤某些养分有一定促进作用,在某种程度上改善了林下土壤,同时魔芋还能带来一定的经济效益。因此,梨树林下种植魔芋是一种可行的种植模式。

关键词：丰水梨昌吉梨魔芋土壤养分

定量亲和色谱-质谱研究美洛昔康与β-环糊精的相互作用

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药学学报 2015年第9期50卷 1167-1173页

作者：王彩芬李卓王小波李海燕张继稳孙立新沈阳药科大学辽宁沈阳110016 中国科学院上海药物研究所上海201203

药物与环糊精的结合速率常数、解离速率常数是药物从给药系统中解离、吸收的基本动力学常数,但现有研究多集中于结合平衡常数K。本文基于定量亲和色谱技术(quantitative high-performance affinity chromatography),发展了测定药物-环... 详细信息

药物与环糊精的结合速率常数、解离速率常数是药物从给药系统中解离、吸收的基本动力学常数,但现有研究多集中于结合平衡常数K。本文基于定量亲和色谱技术(quantitative high-performance affinity chromatography),发展了测定药物-环糊精超分子表观解离速率常数(koff,app)的定量亲和色谱-质谱方法。采用质谱检测器,经色谱峰拟合获得不同流速下药物和不保留物质尿嘧啶在β-环糊精柱上的保留时间与半峰宽,计算药物与不保留物质尿嘧啶的塔板高度(HR与HM,C);根据药物和不保留物质尿嘧啶的扩散系数差异与静态流动相传质阻抗,计算获得理论不保留物质的塔板高度HM,T。以(HR-HM,T)对uk/(1+k)2进行线性回归,根据斜率计算得到多流速条件下美洛昔康和对照药物(对乙酰氨基酚)的koff,app分别为0.13±0.00和4.83±0.10 s-1。根据美洛昔康的结合平衡常数K(12.53 L·mol-1),计算得到表观结合速率常数kon,app为1.63 L·mol-1·s-1。本法简便快速、重复性好,为评价药物与β-环糊精相互作用动力学提供了新的方法。

关键词：定量亲和色谱-质谱美洛昔康 β-环糊精解离速率常数

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大湄公河次地区构造单元划分

沉积与特提斯地质 2004年第4期24卷 13-20页

作者：李兴振刘朝基丁俊成都地质矿产研究所四川成都610082

大湄公河次地区在地质构造上是西南三江构造带和华南加里东褶皱带的向南或南西的延伸。在理清了各构造单元的延伸趋势及其相互关系的基础上,对该区大地构造单元作了统一划分和对比。以印缅山脉结合带、澜沧江文冬劳勿结合带、金沙江 ... 详细信息

大湄公河次地区在地质构造上是西南三江构造带和华南加里东褶皱带的向南或南西的延伸。在理清了各构造单元的延伸趋势及其相互关系的基础上,对该区大地构造单元作了统一划分和对比。以印缅山脉结合带、澜沧江文冬劳勿结合带、金沙江哀牢山马江结合带作为主结合带,将该区划分为印澳板块、中缅马陆块、印支陆块和华南陆块4个一级单元。然后在亲冈瓦纳的中缅马陆块和亲华南型的印支陆块内再以次级结合带分别划分出4个二级构造单元:亲冈瓦纳型的西缅微陆块、腾冲毛淡棉微陆块,保山掸泰微陆块、临沧景栋微陆块,亲华南型的景洪帕府东马来西亚微陆块、思茅大叻微陆块、昆嵩微陆块和长山微陆块;华南陆块以越北斋江结合带为界分为扬子和华夏两微陆块。简要论述了各构造单元的基本地质特征,提出将可可西里澜沧江文冬劳勿结合带作为南部冈瓦纳大陆和北部劳亚大陆的分界,指出昆嵩微陆块和长山微陆块是华夏微陆块的南西延伸,其西部的对应体可能是昌都微陆块。

关键词：大湄公河次地区构造单元划分陆块

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一主多备集群式控制器设计与实现

福建电脑 2020年第10期36卷 9-13页

作者：董文文郭志亮吉祥钻杨宝军 63780部队海南三亚572000

针对软件定义网络中控制器单点(Software Defined Network,SDN)运行隐患的问题,本文设计一种基于ryu控制器的一主多备集群式控制器(Cluster ryu Controller,CRC),实现自定义OVS交换机(OpenVSwitch)连接、事件上报、状态查看、流表下发... 详细信息

针对软件定义网络中控制器单点(Software Defined Network,SDN)运行隐患的问题,本文设计一种基于ryu控制器的一主多备集群式控制器(Cluster ryu Controller,CRC),实现自定义OVS交换机(OpenVSwitch)连接、事件上报、状态查看、流表下发等功能。通过ryu+mininet工具进行仿真实验,结果表明,当CRC中某一控制器出现故障时,不会影响到CRC与整个网络的稳定运行,有效提升SDN网络的健壮性与可靠性。

关键词： SDN ryu控制器 OVS交换机集群式

2010年中国CHINET尿液标本中细菌的分布和耐药性监测

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中国感染与化疗杂志 2012年第4期12卷 241-250页

作者：朱德妹汪复胡付品倪语星孙景勇王传清王爱敏俞云松杨青徐元宏沈继录孙自镛陈中举徐英春张小江单斌杜艳卓超苏丹虹胡云建艾效曼张朝霞季萍贾蓓黄文祥张泓孔菁魏莲花吴玲复旦大学附属华山医院上海200040 中国医学科学院附属协和医院浙江大学医学院附属第一医院上海交通大学医学院附属瑞金医院华中科技大学同济医学院附属同济医院复旦大学附属儿科医院安徽医科大学第一附属医院上海交通大学附属上海儿童医院新疆医科大学附属第一医院昆明医学院第一附属医院广州医学院第一附属医院呼吸疾病研究所卫生部北京医院重庆医科大学附属第一医院甘肃省人民医院

目的了解国内主要地区14所教学医院尿标本中的临床分离菌及其对常用抗菌药物的耐药性。方法采用K-B法按统一方案进行细菌药物敏感试验。按CLSI 2010版标准判断结果。结果 2010年1—12月各医院尿标本临床分离菌共9 301株;占临床分离菌株... 详细信息

目的了解国内主要地区14所教学医院尿标本中的临床分离菌及其对常用抗菌药物的耐药性。方法采用K-B法按统一方案进行细菌药物敏感试验。按CLSI 2010版标准判断结果。结果 2010年1—12月各医院尿标本临床分离菌共9 301株;占临床分离菌株的19.4%(9 301/47 850)。其中革兰阳性菌2 403株,占25.8%,革兰阴性菌6 898株,占74.2%。以大肠埃希菌最为多见,占49.0%;其次为肠球菌属细菌占22.1%。约68%的菌株分离自住院患者,32%的菌株分离自门急诊患者;约64%的菌株分离自女性患者,36%的菌株分离自男性患者。大肠埃希菌、克雷伯菌属细菌(肺炎克雷伯菌+产酸克雷伯菌)以及奇异变形杆菌中的ESBLs的检出率(58.4%、59.8%和14.4%)与同期CHINET监测的检出率相仿。粪肠球菌和屎肠球菌中均有少数万古霉素耐药株,万古霉素耐药肠球菌(VRE)的检出率粪肠球菌为0.5%(5株),屎肠球菌为2.4%(24株)。粪肠球菌对呋喃妥因、磷霉素和氨苄西林的耐药率≤10%;屎肠球菌除对糖肽类抗生素、利奈唑胺和磷霉素外,对其他测试药的耐药率在40%～94%。大肠埃希菌对碳青霉烯类抗生素的耐药率较同期其他标本分离株略低,铜绿假单胞菌和不动杆菌属细菌对之耐药率则较低。在部分肠杆菌科细菌和不发酵糖革兰阴性杆菌中检出少数泛耐药菌株。结论尿标本分离菌主要为大肠埃希菌、其次为肠球菌属细菌,两者约占70%。VRE的检出率为2.4%。与其他标本分离菌相比,尿标本中分离的大肠埃希菌、铜绿假单胞菌和不动杆菌属细菌对碳青霉烯类抗生素的耐药率较低。不同医院尿培养分离菌对常用抗菌药的耐药率较低,且有很大差异,提示治疗尿路感染应根据本单位细菌耐药性监测资料选用抗菌药物。

关键词：尿液标本细菌耐药性监测细菌药物敏感试验大肠埃希菌泛耐药革兰阴性杆菌万古霉素耐药肠球菌

基于药-靶结合动力学的胰脂肪酶靶点占有率模型建立研究

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中国医院药学杂志 2019年第23期39卷 2391-2396页

作者：冀艳华刘洋杨婷婷杨嘉杨海洋李雪岩潘艳丽汪国鹏北京中医药大学北京102488 中国中医科学院中医药信息研究所北京100700 中财瀚熙生物科技发展有限公司北京101503

目的:建立以胰脂肪酶和已上市药物为媒介的药-靶结合动力学模型,依据动力学参数与肠腔药动学构建靶点占有率模型,以评估药-靶结合动力学参数对体内药效的影响。方法:采用体外酶促反应体系测定胰脂肪酶抑制剂奥利司他和新利司他的半抑制... 详细信息

目的:建立以胰脂肪酶和已上市药物为媒介的药-靶结合动力学模型,依据动力学参数与肠腔药动学构建靶点占有率模型,以评估药-靶结合动力学参数对体内药效的影响。方法:采用体外酶促反应体系测定胰脂肪酶抑制剂奥利司他和新利司他的半抑制浓度(IC50);通过反应进度曲线测定求解表观速率常数(kobs);采用快速稀释法测定药物-酶解离速率常数(koff);采用非线性拟合求解其他关键结合动力学参数;应用药物肠腔药代动力学模型,计算肠道中不同时间药物浓度;构建体内靶点占有率模型,并计算体内不同时间的靶点占有率。结果:测得奥利司他的IC50为19.1 nmol·L^-1,新利司他的IC50为76 nmol·L^-1;2个药物与胰脂肪酶呈时间、浓度依赖的缓慢结合反应,且结合反应属于两步结合模式,结合类型为机制B;可逆性研究结果显示奥利司他和新利司他为不可逆抑制;两药的结合速率常数(kon)分别为76.5×10^4和1.7×10^4 M^-1S^-1,koff分别为0.33×10^-6和8.4×10^-6 S^-1。奥利司他对脂肪酶的靶点占有率在24 h大于90%,新利司他对脂肪酶的靶点占有率在21 h时大于60%。结论:本研究所建立的基于药-靶结合动力学胰脂肪酶靶点占有率模型可用于评估动力学参数对体内药效的影响。

关键词：胰脂肪酶药-靶结合动力学药物肠道药动学模型靶点占有率模型

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen jinhui Chen ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jiNR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise