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Comparative detection of syndecan-2 methylation in preoperative and postoperative stool DNA in patients with colorectal cancer

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World Journal of Gastrointestinal Surgery 2023年第9期15卷 2032-2041页

作者： ji hyeong song Tae Jeong Oh Sungwhan An Kyung Ha Lee ji Yeon Kim jin Soo Kim Department of Surgery Chungnam National University Sejong HospitalSejong 30099South Korea Genomictree Inc.Daejeon 34027South Korea Department of Surgery College of MedicineChungnam National UniversityDaejeon 35015South Korea

BACKGROUND Early detection of colorectal cancer(CRC)is essential to reduce cancer-related morbidity and *** DNA(sDNA)testing is an emerging method for early CRC ***-2(SDC2)methylation is a potential biomarker for the sDNA *** DNA methylation is an early epigenetic event during tumorigenesis and can occur in the normal colonic mucosa during aging,which can compromise the sDNA test *** In this prospective study,we enrolled 151 patients with CRC who underwent curative surgical resection between September 2016 and May *** stool samples were collected from 123 patients and postoperative samples were collected from 122 patients.A total of 104 samples were collected from both preoperative and postoperative *** promoter methylation of SDC2 in sDNA was assessed using linear target enrichment quantitative methylation-specific real-time polymerase chain *** parameters were analyzed using the results of SDC2 *** Detection rates of SDC2 methylation in the preoperative and postoperative stool samples were 88.6%and 19.7%,*** tumor size(3 cm,P=0.019)and advanced T stage(T3–T4,P=0.033)were positively associated with the detection rate of SDC2 methylation before *** sex was associated with false positives after surgery(P=0.030).Cycle threshold(CT)values were significantly decreased postoperatively compared with preoperative values(P<0.001).The postoperative negative conversion rate for preoperatively methylated SDC2 was 79.3%(73/92).CONCLUSION Our results suggested that the SDC2 methylation test for sDNA has acceptable sensitivity and ***,small size and early T stage tumors are associated with a low detection rate of SDC2 *** the cycle threshold values significantly decreased after surgery,SDC2 methylation test for sDNA might have a diagnostic value for CRC.

关键词： Biomarkers DNA methylation Syndecan-2 Colorectal cancer

Exciton radiative lifetime in CdSe quantum dots

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Journal of Semiconductors 2023年第3期44卷 104-113页

作者： Zhimin ji Zhigang song State Key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Colloidal CdSe quantum dots(QDs)are promising materials for solar cells because of their simple preparation pro-cess and compatibility with flexible *** QD radiative recombination lifetime has attracted enormous attention as it affects the probability of photogenerated charges leaving the QDs and being collected at the battery ***,the scaling law for the exciton radiative lifetime in CdSe QDs is still a *** article presents a novel explanation that recon-ciles this *** calculations agree with the experimental measurements of all three divergent trends in a broadened energy ***,we proved that the exciton radiative lifetime is a consequence of the thermal average of decays for all thermally accessible exciton *** of the contradictory size-dependent patterns reflects this trend in a specific size *** the optical band gap increases,the radiative lifetime decreases in larger QDs,increases in smaller QDs,and is weakly depend-ent on size in the intermediate energy *** study addresses the inconsistencies in the scaling law of the exciton life-time and gives a unified interpretation over a widened ***,it provides valuable guidance for carrier separa-tion in the thin film solar cell of CdSe QDs.

关键词： solar cells CdSe quantum dot radiative lifetime scaling law optical band gap exciton fine structure room temperat-ure

Practical Privacy-Preserving ROI Encryption System for Surveillance Videos Supporting Selective Decryption

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Computer Modeling in Engineering & Sciences 2024年第12期141卷 1911-1931页

作者： Chan hyeong Cho Hyun Min song Taek-Young Youn Department of Cyber Security Dankook UniversityYonginGyeonggi-Do16890Republic of Korea

With the advancement of video recording devices and network infrastructure,we use surveillance cameras to protect our valuable *** paper proposes a novel system for encrypting personal information within recorded surveillance videos to enhance efficiency and *** proposed method leverages Dlib’s CNN-based facial recognition technology to identify Regions of Interest(ROIs)within the video,linking these ROIs to generate unique *** IDs are then combined with a master key to create entity-specific keys,which are used to encrypt the ROIs within the *** system supports selective decryption,effectively protecting personal information using surveillance ***,the system overcomes the limitations of existing ROI recognition technologies by predicting unrecognized frames through *** research validates the proposed technology through experimental evaluations of execution time and post-processing techniques,ensuring comprehensive personal information *** for setting the thresholds used in this process are also *** the proposed method could serve as an effective solution to security vulnerabilities that traditional approaches fail to address.

关键词： Privacy de-identification selective decryption surveillance video

Natural nematicidal active compounds:Recent research progress and outlook

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Journal of Integrative Agriculture 2021年第8期20卷 2015-2031页

作者： CHEN ji-xiang song Bao-an State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering/Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education/Guizhou UniversityGuiyang 550025P.R.China

Plant-parasitic nematodes cause substantial economic losses to global agriculture *** use of nematicides is an effective way of controlling plant-parasitic ***,the long-term use of traditional organophosphorus and carbamate chemical nematicides can lead to increased nematode *** the increasing awareness of the necessity for the protection of the environment and human health,highly toxic nematicides no longer meet the developmental requirements of modern ***,many studies have been undertaken on the isolation and nematicidal activity of natural products against plant-parasitic nematodes and Caenorhabditis *** an important model nematode,*** plays a vital reference role in studying plant-parasitic nematodes regarding nematicidal activity,metabolic mechanism,and modes of action and *** reviewed the latest research progress of natural nematicidal active compounds against plantparasitic nematodes and *** over the past ten years,discussed the structure-activity relationship and mechanism of action,and examined the development and application of natural nematicidal active compounds.

关键词： natural products nematicides research progress plant-parasitic nematodes

Adaptive waveform design based on Morlet wavelet for ultra-wideband MIMO radar

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Journal of Systems Engineering and Electronics 2016年第2期27卷 362-369页

作者： Chenhe ji Yaoliang song Qiang Du School of Electronic and Optical Engineering Nanjing University of Science and Technology

For the issue of deterioration in detection performance caused by dynamically changing environment in ultra-wideband（UWB） multiple input multiple output（MIMO） radar, this paper proposes a novel adaptive waveform design which is aimed to improve the ability of discriminating target and clutter from the radar scene. Firstly, a sequence of Morlet wavelet pulses with frequency hopping and pulse position modulation by Welch-Costas array is designed. Then a waveform optimization solution is proposed which is achieved by applying the minimization mutual-information（MI） strategy. After that, with subsequent iterations of the algorithm, simulation results demonstrate that the optimal waveform design method brings an improvement in the target detection ability in the presence of noise and clutter.

关键词： ultra-wideband(UWB) radar multiple input multiple output(MIMO) waveform design Morlet wavelet mutual information(MI)

Infinitesimal dividing modeling method for dual suppliers inventory model with random lead times

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Journal of Systems Engineering and Electronics 2009年第3期20卷 527-536页

作者： ji Pengcheng song Shiji Wu Cheng Dept. of Automation Tsinghua Univ. Beijing 100084 P. R. China

As one of the basic inventory cost models, the （Q, τ）inventory cost model of dual suppliers with random procurement lead time is mostly formulated by using the concepts of ＂effective lead time＂ and ＂lead time demand＂, which may lead to an imprecise inventory cost. Through the real-time statistic of the inventory quantities, this paper considers the precise （Q, τ） inventory cost model of dual supplier procurement by using an infinitesimal dividing method. The traditional modeling method of the inventory cost for dual supplier procurement includes complex procedures. To reduce the complexity effectively, the presented method investigates the statistics properties in real-time of the inventory quantities with the application of the infinitesimal dividing method. It is proved that the optimal holding and shortage costs of dual supplier procurement are less than those of single supplier procurement respectively. With the assumption that both suppliers have the same distribution of lead times, the convexity of the cost function per unit time is proved. So the optimal solution can be easily obtained by applying the classical convex optimization methods. The numerical examples are given to verify the main conclusions.

关键词： inventory precise model random lead times dual supplier infinitesimal dividing method optimiza- tion.

Numerical simulation of humping phenomenon in high speed gas metal arc welding

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Frontiers of Materials Science 2011年第2期5卷 90-97页

作者： ji CHEN Chuan-song WU State Key Lab of Advanced Welding Production Technology Harbin Institute of Technology Harbin 150001 China Institute of Materials Joining Shandong University Jinan 250061 China

It is of great significance to obtain a thorough understanding of the physical mechanisms responsible for humping bead phenomenon in high speed gas metal arc welding （GMAW） in order to raise welding efficiency. Experiments were conducted to observe the weld pool behaviors in high speed GMAW, and it was found that both the severely deformed weld pool surface and strong backward flowing play a dominant role in humping bead formation. In this study, a mathematical model is developed to quantitatively analyze the forming mechanism of humping beads for high speed GMAW through considering both the momentum and heat content distribution of the backward flowing molten metal inside the weld pool. The transient development of temperature profiles in the weld pool with severe deformation demonstrates the humping bead forming process under some welding conditions. The predicted and measured humping bead dimensions are in agreement.

关键词： numerical simulation humping weld bead high-speed GMAW

Metal@Silica Yolk-Shell Nanostructures as Versatile Bifunctional Nanocatalysts

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Nano Research 2011年第1期4卷 33-49页

作者： ji Chan Park Hyunjoon song Department of Chemistry Korea Advanced Institute of Science and Technology （KAIST） Daejeon 305-701 Republic of Korea

Recent developments in nanochemistry offer precise morphology control of nanomaterials, which has significant impacts in the field of heterogeneous catalysis. Rational design of bifunctional catalysts can influence various aspects of catalytic properties. In this review, a new class of bifunctional catalysts with a metal@silica yolk-shell nanostructure is introduced. This structure has many advantages as a heterogeneous catalyst since it ensures a homogeneous environment around each metal core, and particle sintering is effectively eliminated during high temperature reactions. The catalysts exhibit high activity and recyclability in gas- and solution-phase reactions. It is anticipated that appropriate selection of bifunctional components and optimal structural control will significantly further enhance the catalytic properties, and enable target reaction-oriented development of new catalysts.

关键词： Yolk-shell nanostructure nanocatalyst bifunctionality metal nanoparticles heterogeneous catalytic reactions

A Free Surface Sharpening Strategy Using Optimization Method

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Journal of Thermal Science 2015年第6期24卷 544-548页

作者： song Hongchao ji Lucheng TU Shuangzhang School of Aerospace Engineering Beijing Institute of Technology Department of Computer Engineering Jackson State University

VOF method which consists in transporting a discontinuous marker variable is widely used to capture the free surface in computational fluid *** is numerical dissipation in simulations involving the transport of the *** dissipation makes the free surface lose its physical nature.A free surface sharpening strategy based on optimization method is presented in the *** strategy can keep the location of the free surface and local mass conservation at both time,and can also keep free surface in a constant *** is independent on the types of solvers and *** famous cases were chosen for verifying the free surface sharpening strategy *** show that the strategy has a very good performance on keeping local mass *** efficiency of prediction of the free surface is improved by applying the *** modeling of flow details such as drops can also be captured by this method.

关键词： VOF free surface sharpening optimization method local mass conservation